• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.45-45
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• 2003

To evaluate remodeling of infarcted myocardium with contrast-enhanced MRI (co-MRI) at true end-diastole (ED) MRI was performed with a Gyroscan Intera (1.5 Tesla, Philips, Netherlands) in 13 patients with acute subendocardial myocardial infarction. The First exam was done 0-15 days (mean 5.2days) after symptom onset and the second exam 28-88days (mean 49 days) after the first exam. Ce-MRI encompassing the entire left ventricle was performed with a multi-shot, turbo-field-echo, breath-hold sequence and a non-selective, inversion prepulse 10 minutes after the intravenous injection of Gd-DTPA at a dose of 0.2 mmol/kg body weight. To allow the long TD, ECG synchronization should use two RR-intervals for one acquisition of a segment of k-space by setting the heart rate to half that of the true heart rate. Trigger delay time (TD) was adjusted to the RR-interval for true end-diastolic imaging. The other typical parameters were TR=5.4ms, TE=1.6ms, voxel size=1.37${\times}$1.37${\times}$10mm, k-space data segmented into 8 segments with 32 lines of segment per two cycles over 16 cardiac circles. The thickness of hyperenhanced myocardium and epicardially nonenhanced myocardium were followed.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.92-92
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• 2003

To evaluate remodeling of infarcted myocardium with contrast-enhanced MRI (co-MRI) at true end-diastole (ED) MRI was performed with a Gyroscan Intera (1.5 Tesla, Philips, Netherlands) in 13 patients with acute subendocardial myocardial infarction. The First exam was done 0-15 days (mean 5.2days) after symptom onset and the second exam 28-88days (mean 49 days) after the first exam. Ce-MRI encompassing the entire left ventricle was peformed with a multi-shot, turbo-field-echo, breath-hold sequence and a non-selective, inversion prepulse 10 minutes after the intravenous injection of Gd-DTPA at a dose of 0.2 mmol/kg body weight. To allow the long TD, ECG synchronization should use two RR-intervals for one acquisition of a segment of k-space by setting the heart rate to half that of the true heart rate. Trigger delay time (TD) was adjusted to the RR-interval for true end-diastolic imaging. The other typical parameters were TR=5.4ms, TE=1.6ms, voxel size=1.37$\times$1.37$\times$10mm, k-space data segmented into 8 segments with 32 lines of segment per two cycles over 16 cardiac cycles. The thickness of hyperenhanced myocardium and epicardially nonenhanced myocardium were followed.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.223-224
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• 2015

We present the results of visual double stars speckle observations from 2013 using a Zeiss Double Refractor 60 cm with visual focal length f = 1,078 cm, and CCD SBIG ST-402 MEA. A Bessel V filter with ${\lambda}=550nm$ was placed in front of the CCD camera to reduce the chromatic aberration of the objective lens. The objects selected for this observation were calibration candidates and program stars with separations ranging from 0.9-6 arc second, and were located in both the northern and southern hemispheres. Seeing at Bosscha Observatory is generally 1-2 arc second, imposing a limit on visual double star separation below which the system cannot be resolved by long exposure imaging (longer than ~50 ms). Speckle interferometry methods are used to resolve double stars with separations below the typical size of seeing effects. A series of images were captured in fast short-time exposures (~50 ms) using a CCD camera. The result of our experiment shows that our system can be used to measure separations of 0.9 arc second (for systems with small ${\Delta}m$) and ${\Delta}m{\approx}3.7$ (for wide systems).

• Korean Journal of Digital Imaging in Medicine
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• v.15 no.2
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• pp.63-68
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• 2013

Purpose : The relaxation times of tissue in MRI depend on strength of magnetic field, morphology of nuclear, viscosity, size of molecules and temperature. This study intended to analyze quantitatively that materials' temperatures have effects on T1 and T2 relaxation times without changing of other conditions. Materials and Methods : The equipment was used MAGNETOM SKYRA of 3.0T(SIEMENS, Erlagen, Germany), 32 channel spine coil and Gd-DTPA water concentration phantom. To find out T1 relaxation time, Inversion Recovery Spin Echo sequences were used at 50, 400, 1100, 2500 ms of TI. To find out T2 relaxation time, Multi Echo Spin Echo sequences were used at 30, 60, 90, 120, 150, 180, 210, 240, 270 ms of TE. This experiment was scanned with 5 steps from 25 to $45^{\circ}C$. next, using MRmap(Messroghli, BMC Medical Imaging, 2012) T1 and T2 relaxation times were mapped. on the Piview STAR v5.0(Infinitt, Seoul, Korea) 5 steps were measured as the same ROI, and then mean values were calculated. Correlation between the temperatures and relaxation times were analyzed by SPSS(version 17.0, Chicago, IL, USA). Results : According to increase of temperatures, T1 relaxation times were $214.39{\pm}0.25$, $236.02{\pm}0.87$, $267.47{\pm}0.48$, $299.44{\pm}0.64$, $330.19{\pm}1.72$ ms. T2 relaxation times were $180.17{\pm}0.27$, $197.17{\pm}0.44$, $217.92{\pm}0.39$, $239.89{\pm}0.53$, $257.40{\pm}1.77$ ms. With the correlation analysis, the correlation coefficients of T1 and T2 relaxation times were statistically significant at 0.998 and 0.999 (p< 0.05). Conclusion : T1 and T2 relaxation times are increased as temperature of tissue goes up. In conclusion, we suggest to recognize errors of relaxation time caused local temperature's differences, and consider external factors as well in the quantitative analysis of relaxation time or clinical tests.

• Investigative Magnetic Resonance Imaging
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• v.15 no.1
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• pp.48-56
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• 2011

Purpose : The aim of this study is to measure the typical MR variables such as $T_1$- and $T_2$-relaxation times according to morphological characteristics of gold nanopartides as a preliminary study to perform theragnosis using local heating by gold nanopartides. Materials and Methods : Two types of gold nanoparticles were used. Spheres were synthesized by various methods and stirring speed. Rods were synthesized by adding various concentrations of sphere nanopartides. Gold nanopartides were mixed with 2% agarose gel at 1:1 ratio and then signals were acquired using a 1.5T MRI. For the measurements of $T_1$-and $T_2$-relaxation times, TR and TE were varied, respectively. The results were acquired through $T_1$ and $T_2$ curves based on the intensities of MR image using self-developed software. And Statistical analysis was performed. Results : $T_1$ times were measured 1.86 sec and 2.08 sec for sphere and rod, respectively. On the other hands, $T_2$ times were measured 57 ms and 35.45 ms for sphere and rod. Conclusion : The changes of the MR variables according to the morphological characteristics of the gold nanopartides were confirmed. Optimal MR imaging conditions can be obtained by choosing proper TR and TE according to the type of nanoparticles.

• Journal of the Korean Society of Radiology
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• v.13 no.1
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• pp.55-63
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• 2019

It was reported that there were some cases in which signal was not inhibited but high signal appeared in cerebrospinal fluid on FLAIR(fluid attenuated inversion recovery) of MRI(Magnetic Resonance Imaging) in case a person inhales high-concentration oxygen. This study was to prepare basic database. We produced a phantom fixed with agar gel and by using it, obtained the images of the signals of normal saline into which oxygen was injected and normal saline diluted with contrast media by changing the TI(Inversion Time) of FLAIR technique and analyzed them. In the result of FLAIR technique of MRI using Philips Achieva MR 3.0T in Busan P Hospital, the SNR(Signal to Noise Ratio) of normal saline into which oxygen was injected was higher than the SNR of normal saline into which oxygen was not injected. However, it was not higher than the SNR of normal saline diluted with contrast media. In the TI 1,800ms, we could obtain the images which do not have the rise of the signal due to oxygen. In the CNR(Contrast to Noise Ratio) of normal saline into which oxygen was injected and normal saline diluted with contrast media as well, it was higher in the TI 1,800ms than in the TI 2,800ms that is mainly used clinically. It is thought that the result of this study could be basic database for studies on change of signal of cerebrospinal fluid as a result of injection of oxygen in FLAIR technique of MRI.

• Korean Journal of Remote Sensing
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• v.25 no.6
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• pp.517-529
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• 2009

Many satellite image fusion techniques have been developed in order to produce a high resolution multispectral (MS) image by combining a high resolution panchromatic (PAN) image and a low resolution MS image. Heretofore, most high resolution image fusion techniques have used IKONOS and QuickBird images. Recently, GeoEye-1, offering the highest resolution of any commercial imaging system, was launched. In this study, we have experimented with GeoEye-1 images in order to evaluate which fusion algorithms are suitable for these images. This paper presents compares and evaluates the efficiency of five image fusion techniques, the $\grave{a}$ trous algorithm based additive wavelet transformation (AWT) fusion techniques, the Principal Component analysis (PCA) fusion technique, Gram-Schmidt (GS) spectral sharpening, Pansharp, and the Smoothing Filter based Intensity Modulation (SFIM) fusion technique, for the fusion of a GeoEye-1 image. The results of the experiment show that the AWT fusion techniques maintain more spatial detail of the PAN image and spectral information of the MS image than other image fusion techniques. Also, the Pansharp technique maintains information of the original PAN and MS images as well as the AWT fusion technique.

• Clinical and Experimental Pediatrics
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• v.54 no.6
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• pp.234-240
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• 2011

Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease of the central nervous system (CNS) that typically presents as a monophasic disorder associated with multifocal neurologic symptoms and encephalopathy. ADEM is considered an autoimmune disorder that is triggered by an environmental stimulus in genetically susceptible individuals. The diagnosis of ADEM is based on clinical and radiological features. Most children with ADEM initially present with fever, meningeal signs, and acute encephalopathy. The level of consciousness ranges from lethargy to frank coma. Deep and subcortical white-matter lesions and gray-matter lesions such as thalami and basal ganglia on magnetic resonance imaging (MRI) are associated with ADEM. In a child who presents with signs of encephalitis, bacterial and viral meningitis or encephalitis must be ruled out. Sequential MRI is required to confirm the diagnosis of ADEM, as relapses with the appearance of new lesions on MRI may suggest either multiphasic ADEM or multiple sclerosis (MS). Pediatric MS, defined as onset of MS before the age of 16, is being increasingly recognized. MS is characterized by recurrent episodes of demyelination in the CNS separated in space and time. The McDonald criteria for diagnosis of MS include evidence from MRI and allow the clinician to make a diagnosis of clinically definite MS on the basis of the interval preceding the development of new white matter lesions, even in the absence of new clinical findings. The most important alternative diagnosis to MS is ADEM. At the initial presentation, the 2 disorders cannot be distinguished with certainty. Therefore, prolonged follow-up is needed to establish a diagnosis.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.6-6
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• 2016

최근 전 지구적인 기후 변화에 따라 수문 순환을 이루고 있는 다양한 수문 기상 인자들의 변동성에 영향을 미치고 있다. 특히, 증발산은 수문순환을 구성하는 중요한 인자로서 대기와 지표간의 상호 작용을 파악하기 위해서는 이에 대한 정확한 이해 및 산정이 필수적이다. 일반적으로 증발산량을 산정하기 위해서 증발 접시 및 에디 공분산 기반 플럭스 타워에서 관측된 지점 자료만을 이용하여 증발산량의 변동성을 파악하는 연구들이 수행되어왔다. 그러나 지점 자료만을 이용하여 증발산량을 산출하게 되면 공간적인 변동성을 파악하는데 있어서 한계점이 발생하게 된다. 이러한 제약 사항을 해결하기 위해서, 인공위성 기반의 수문 기상인자를 물리식 기반 증발산량 산정식의 입력 자료로 구축하여 증발산량을 산정하고 이에 대한 시 간적인 변동성을 파악하는 연구들이 활발히 이루어지고 있다. 인공위성 기반 증발산량 산정 알고리즘의 대표적인 예로 공기동역학적 항과 에너지 수지 항들을 동시에 고려할 수 있는 Penman-Monteith 방법을 근간으로 수정하여 만들어낸 Remote Sensing based Penman-Monteith (RS-PM) 알고리즘이 있다. 그러나 RS-PM 기반의 증발산량 경우 태양복사열, 풍속, 온도, 습도와 같은 많은 수문기상인자들이 입력 자료를 요구한다. 이에 따라, 본 연구에서는 기존의 방법에 비해 상대적으로 적은 입력 자료를 사용하는 Modified Satellite-Based Priestley-Taylor (MS-PT) algorithm의 적용성을 평가하기 위해 MODerate-Resolution Imaging Spectroradiometer (MODIS) 자료를 이용하여 한반도에서 순복사에너지 (Net radiation) 및 실제 증발산량 (Actual evapotranspiration)을 산정하였다. 또한, 이에 대한 검증을 위해 청미천 유역에 설치되어있는 에디 공분산 기반 플럭스 타워에서 관측된 순복사 에너지 및 실제 증발산량에 대한 통계적 검증을 실시하였다.

• Korean Journal of Radiology
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• v.21 no.8
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• pp.978-986
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• 2020

Objective: To compare native and post-contrast T1 mapping with late gadolinium enhancement (LGE) imaging for detecting and measuring the microvascular obstruction (MVO) area in reperfused acute myocardial infarction (MI). Materials and Methods: This study included 20 patients with acute MI who had undergone 1.5T cardiovascular magnetic resonance imaging (CMR) after reperfusion therapy. CMR included cine imaging, LGE, and T1 mapping (modified look-locker inversion recovery). MI size was calculated from LGE by full-width at half-maximum technique. MVO was defined as an area with low signal intensity (LGE) or as a region of visually distinguishable T1 values (T1 maps) within infarcted myocardium. Regional T1 values were measured in MVO, infarcted, and remote myocardium on T1 maps. MVO area was measured on and compared among LGE, native, and post-contrast T1 maps. Results: The mean MI size was 27.1 ± 9.7% of the left ventricular mass. Of the 20 identified MVOs, 18 (90%) were detected on native T1 maps, while 10 (50%) were recognized on post-contrast T1 maps. The mean native T1 values of MVO, infarcted, and remote myocardium were 1013.5 ± 58.5, 1240.9 ± 55.8 (p < 0.001), and 1062.2 ± 55.8 ms (p = 0.169), respectively, while the mean post-contrast T1 values were 466.7 ± 26.8, 399.1 ± 21.3, and 585.2 ± 21.3 ms, respectively (p < 0.001). The mean MVO areas on LGE, native, and post-contrast T1 maps were 134.1 ± 81.2, 133.7 ± 80.4, and 117.1 ± 53.3 mm², respectively. The median (interquartile range) MVO areas on LGE, native, and post-contrast T1 maps were 128.0 (58.1-215.4), 110.5 (67.7-227.9), and 143.0 (76.7-155.3) mm², respectively (p = 0.002). Concordance correlation coefficients for the MVO area between LGE and native T1 maps, LGE and post-contrast T1 maps, and native and post-contrast T1 maps were 0.770, 0.375, and 0.565, respectively. Conclusion: MVO areas were accurately delineated on native T1 maps and showed high concordance with the areas measured on LGE. However, post-contrast T1 maps had low detection rates and underestimated MVO areas. Collectively, native T1 mapping is a useful tool for detecting MVO within the infarcted myocardium.