• Korean Journal of Schizophrenia Research
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• v.22 no.2
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• pp.42-50
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• 2019

Objectives: In this preliminary study, we investigated the clinical characteristics of patients who were first diagnosed with psychotic disorder and explored the impact of the adherence to antipsychotics on long-term medical use. Methods: All national health insurance claims related to psychotic disorders including gender, age, income, and drug compliance, from January 1, 2008 to December 31, 2015, were examined. With trend test using Medication Possession Ratio (MPR), we compared the medical use between the compliant group (MRP≥0.8) and the comparative non-compliant group (0.2≤MPR<0.8). Results: Among 28,095 participants in total, 16,239 patients (57.8%) were diagnosed as schizophrenia; the 30s were the most common (n=7,151, 25.5%). Drug compliance was generally low regardless of the diagnosis and was the lowest among 20s with the 40-60% range of income. The compliant group showed lower psychiatric and medical use than the comparative group in the following years (p<0.0001). Conclusion: These findings suggest that patients in the 20s and 30s with the 40-60% range of income, who are diagnosed with schizophrenia at the first psychiatric visit, may need more clinical and political attention. The results also emphasize the importance of initial drug adherence to antipsychotics in reducing long-term psychiatric costs.

• Investigative Magnetic Resonance Imaging
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• v.1 no.1
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• pp.94-102
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• 1997

Purpose: There have been some efforts to diagnose intracranial aneurysm through a non-invasive method using MRA, although the process may be difficult when the lesion is less than 3mm. The present study prospectively compares the results of high resolution, fast speed slice interpolation MRA and DSA thereby examing the potentiality of primary non-invasive screening test. Materials and Methods: A total of 26 cerebral aneurysm lesions from 14 patients with subarachnoid hemorrhage from ruptured aneurysm (RA) and 5 patients with unruptured aneurysm(UA). In all subjects, MRA was taken to confirm the vessel of origin, definition of aneurysm neck and the relationship of the aneurysm to nearby small vessels, and the results were compared with the results of DSA. The images were obtained with 1.5T superconductive machine (Vision, Siemens, Erlangen, Germany) on 4 slabs of MRA using slice interpolation. The settings include TR/TE/FA=30/6.4/25, matrix $160{\times}512$, FOV $150{\times}200$, 7minutes 42 seconds of scan time, effective thickness of 0.7 mm and an entire thickness of 102. 2mm. The images included structures from foramen magnum to A3 portion of anterior cerebral artery. MIP was used for the image analysis, and multiplanar reconstruction (MPR) technique was used in cases of intracranial aneurysm. Results: A total of 26 intracranial aneurysm lesions from 19 patients with 2 patients having 3 lesion, 3 patients having 2 lesions and the rest of 14 patients having 1 lesion each were examined. Among those, 14 were RA and 12 were UA. Eight lesions were less than 2mm in size, 9 lesions were 3-5mm, 7 were 6-9mm and 2 were larger than IOmm. On initial exams, 25 out of 26 aneurysm lesions were detected in either MRA or DSA showing 96% sensitivity. Specificity cannot be estimated since there was no true negative of false positive findings. When MRA and MPR were used concurrently for the confirmation of size and shape, the results were equivalent to those of DSA, while in the confirmation of aneurysm neck and parent vessels, the concurrent use of MRA and MPR was far superior to the sole use of either MRA or DSA. Conclusion: High resolution MRA using slice interpolation technique showed equal results as those of DSA for the detection of intracranial aneurysm, and may be used as a primary non-invasive screening test in the future.

• BMB Reports
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• v.31 no.3
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• pp.209-220
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• 1998

How did nature create the first set of genes at the beginning of life on Earth? One of the goals of molecular biology is to elucidate the fundamental rules governing how genes and, therefore, proteins were created. Through experiments carried out in the emerging field of "in vitro" or "benchtop" evolution studies, we are gaining new insights into the origins of genes and proteins as well as the origins of their functions (e.g., catalysis). In this review, I present an overview of recent experimental approaches to the question of the origin and evolution of genes. In addition, I will introduce a novel in vitro protein emergence system that was recently developed in my laboratory.

• Journal of KIISE:Software and Applications
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• v.30 no.3_4
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• pp.285-292
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• 2003

Existing MPEG-4 players have limitation of screen blinks and drops of object rendering speed when user insert, delete, and replace objects on scenes. In this paper, an Object Priority Order Composition operated through the MPEG-4 player is proposed. This composition is the method for presentation user can insert, delete, and replace scene objects more efficiently. Therefore, this composition can show the MPEG-4 multimedia scenes without blinks and delays on MPR-4 player may seem random and natural.

• The KIPS Transactions:PartB
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• v.8B no.2
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• pp.164-172
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• 2001

본 논문에서는 시각화와 공간적, 속성 혼합 쿼리를 수행할 수 있는 관계형 데이터베이스를 설계하고 구현하였다. 쿼리에 사용되는 데이터형은 슬라이스, MPR, 볼륨 렌더링으로 시각화할 수 있으며, 쿼리는 아탈라스를 이용하는 경우와 그렇지 않는 경우를모두 고려하였다. 영상 데이터는 공간충전 곡선으로 공간적으로 클러스트링한 후 무손실 압축하여 데이터베이스에 저장된다. 본 논문은 저장 데이터의 양을 줄이기 위하여 관심영역의 크기에 따라 창의 크기가 변하는 적응적 Hibert 곡선을 제안하였으며, 실험에서 Hibert 곡선의 적용한 데이터보다 약 1.15배 높은 압축율을 보였다. 또한 아틀라스에 대한 뇌종양의 공간적 쿼리 결과를 통하여 본 의료 영상 데이터베이스의 유용성을 보였다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.1
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• pp.50-67
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• 2015

The Cognitive Radio (CR) paradigm in tactical ad hoc networks is an important element of future military communications for network-centric warfare. This paper presents a novel Cognitive Link State Routing protocol for CR-based tactical ad hoc networks. The proposed scheme provides prompt and reliable routes for Primary User (PU) activity through procedures that incorporate two main functions: PU-aware power adaptation and channel switching. For the PU-aware power adaptation, closer multipoint relay nodes are selected to prevent network partition and ensure successful PU communication. The PU-aware channel switching is proactively conducted using control messages to switch to a new available channel based on a common channel list. Our simulation study based on the ns-3 simulator demonstrates that the proposed routing scheme delivers significantly improved performance in terms of average end-to-end delay, jitter, and packet delivery ratio.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.5 no.1
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• pp.38-43
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• 2004

We designed and implemented a medical image query system, including a relational database and DBMS (database management system), which can visualize image data and can achieve spatial, attribute, and mixed queries. Image data used in querying can be visualized in slice, MPR(multi-planner reformat), volume rendering, and overlapping on the query system. To reduce spatial cost and processing time in the system. brain images are spatially clustered, by an adaptive Hilbert curve filling, encoded, and stored to its database without loss for spatial query. Because the query is often applied to small image regions of interest(ROI's), the technique provides higher compression rate and less processing time in the cases.

• Agribusiness and Information Management
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• v.4 no.2
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• pp.32-41
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• 2012

Studies have shown that the future of the wine market rests on the effective and efficient changes in technology to the supply chain used by most of the major global players. In today's wine industry, companies are faced with the ever-shifting demand for their products, strict regulation and increasing price competition. Even at that, mature companies in the wine industry are succeeding by scaling up production, streamlining their supply chains, expanding into new geographic areas, implementing more efficient processes, cleverly marketing products, and focusing on ever closer relationships with suppliers, partners and customers. However, this paper looks at supply chain challenges in the wine industry from a global perspective presented in the inbound, manufacturing and outbound processes as well as offer effective solutions in order for companies to gain a competitive advantage and succeed on a global level.

• Imaging Science in Dentistry
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• v.32 no.1
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• pp.35-39
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• 2002

Purpose: The altered gantry angle during scanning for some multiplanar reconstruction CT program (CT/MPR) may cause distortion of the image. The aim of this study was to ascertain whether there is a image distortion in a reformatted image when the gantry and the object are equally inclined using ToothPix and DentaScan program. Materials and Methods: A resin block model with four cylindrical holes and a human dry mandible were used. Two MPR software packages, ToothPix and DentaScan program, were used for reformatted panoramic images. The block and the gantry were equally inclined at 0°, 15°, and 30°. Results: With ToothPix program, a resin block model with empty holes and a dry mandible showed inclined images in the reformatted panoramic image. Increasing the gantry angle, the depth and inclination of the holes were increased in the reformatted central panoramic images. However, a resin block model with gutta perch a in its holes and a dry mandible with a wire in its mandibular canal didn't show image distortion. With DentaScan program, image distortion was not seen in any situation. Conclusion: ToothPix program may distort the reformatted image when the gantry angle is not at zero degrees. However, with DentaScan program, the patient may be positioned comfortably and the gantry can be adjusted to the patient positioning.

• Journal of Korean Society of Transportation
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• v.36 no.1
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• pp.38-50
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• 2018

Emerging automated driving environments will lead to a mixed traffic flow depending on the interaction between automated vehicles (AVs) and manually driven vehicles (MVs) because the market penetration rate (MPR) of AVs will gradually increase over time. Understanding the characteristics of mixed traffic conditions, and developing a method to control both AV and MV maneuverings smoothly is a backbone of the traffic management in the era of automated driving. To facilitate smooth vehicle interactions, the maneuvering of AVs should be properly determined by various traffic and road conditions, which motivates this study. This study investigated whether the aggressiveness of AV maneuvering, defined as automated driving aggressiveness (ADA), affect the performance of mixed traffic flow. VISSIM microscopic simulation experiments were conducted to derive proper ADAs for satisfying both the traffic safety and the operational efficiency. Traffic conflict rates and average travel speeds were used as indicators for the performance of safety and operations. While conducting simulations, level of service(LOS) and market penetration rate(MPR) of AVs were also taken into considerations. Results implies that an effective guideline to manage the ADA under various traffic and road conditions needs to be developed from the perspective of traffic operations to optimize traffic performances.