• YAKHAK HOEJI
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• v.41 no.1
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• pp.86-93
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• 1997

Even though both N-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) and 6-hydroxydopamine have been widely used to establish the experimental model for dopaminergic neuronal ce ll death. mechanisms underlying this phenomenon have not been firmly explored. To investigate how these dopaminergic neurotoxins induce neuronal cell death, murine dopaminergic neuronal cell line, MN9D cells were treated with various concentration of either 6-hydroxydopamine or active form of MPTP, N methyl-4-phenylpyridinium (MPP$^+$). Treatment of cells with 5-100 uM 6-hydroxydopamine resulted in apoptotic cell death whereas cell death induced by 5~50 uM MPP$^+$ was not demonstrated typical apoptotic characteristics such as cell shrinkage, apoptotic body and nuclear condensation. Cell death induced by 6-hydroxydopamine was partially blocked in the presence of antioxidants including soluble form of vitamin E or desferrioxamine suggesting that generation of oxidative stress may be associated with 6-hydroxydopamine-induced cell death in MN9D cells. In contrast, MPP$^+$-induced cell death was not blocked by treatment with any of antioxidants tested. As previously demonstrated that MPP$^+$ caused metabolic alterations such as glucose metabolism, removal of glucose from the medium partially inhibited MPP$^+$-induced cell death suggesting excessive cycles of glycolysis may be associated with MPP$^+$-induced cell death. Taken together, these studies demonstrate that two types of dopaminergic neurotoxins recruit distinct neuronal cell death pathways.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.21 no.5
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• pp.9-15
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• 2022

Discarded bio-wastes, such as seeds and rinds, cause environmental problems. Multiple studies have recycled bio-wastes as eco-friendly energy sources to solve these problems. This study uses bio-waste to fabricate a mandarin peel powder based triboelectric nanogenerator (MPP-TENG). The MPP-TENG is based on the contact separation mode. It generates an open-circuit voltage and short-circuit current of 156V and 2µA, respectively. In addition, MPP-TENG shows stable operation over continuous 3000s without any deviation in output. Also, the device exhibits maximum power density of 5.3㎼/cm² when connected to a resistance of 100MΩ. In an energy storage capacity test for 1000s, the MPP-TENG stores an energy of 171.6µJ in a 4.7µF capacitor. The MPP-TENG can power 9 blue LEDs and 54 green lettering LEDs. These results confirm that the MPP-TENG can provide a new avenue for eco-friendly energy harvesting device fabrication.

• The Journal of the Korea Contents Association
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• v.11 no.12
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• pp.586-596
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• 2011

In the IT industry, processing units of IT applications are getting smaller and high efficient. Furthermore, the realization of various smart functions is highly feasible now due to advances in sensing technology. The service infrastructures on high efficient and compact mobile devices are applied to various areas. These also could be possessed by users and is built into the devices. Currently, studies on the UX(User Experience) field to attempt an analysis and prediction of user's information are continuing with reference to the UI(User Interface). However, research on the common framework of classification and storing the user-information, and standardization of form has not been attempted yet. In this study, we proposed the AUX(Associative user Experience) model and process structure to store various empirical data by users. The AUX model expressed a diversity of user's empirical data using extended E-TCPN model. And also, we expressed the data structure using XML with reference to the application of AUX model. This expressed model and separation of process structure guarantee its specialty, productivity and flexibility through the humanistic characteristics of users and the independence of technical process structure. The AUX model maps out the AUX information process architecture and expressed the process with the improved MPP algorithm, to analyze of its performance. The simulation of movements applying to MPP traffic allocation of VOD is used to analyze of its performance. The playback deviation of MPP Graphic Allocation Algorism where the AUX model was applied was improved by 10.41% more than the one where it was not applied. As a result of that, playback performance has improved due to the conversion of AUX with accessing media, content of users and dynamic traffic allocation such as MPI and CPI.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.6
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• pp.105-113
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• 2013

In this paper a micro solar energy harvesting system with MPPT(Maximum Power Point Tracking) control using a miniature PV(photovoltaic) cell of which the output is less than 0.5V is proposed. The MPPT control is implemented using linear relationship between the open-circuit voltage of a PV cell and its MPP(Maximum Power Point) voltage such that a pilot PV cell can track the MPP of the main PV cell in real time. The proposed circuit is designed in 0.18um CMOS process. The designed chip area is $900um{\times}1370um$ including a load charge pump and pads. Measured results show that the designed system can track the MPP voltage changes with variations of light intensity. The designed circuit with MPPT control delivers MPP voltages to load even though the load is heavy such that it can supply more power when the MPPT control is applied. The proposed circuit does not require any precharged battery resulting in more suitability for miniaturized self-powered systems compared to the existing works.

• Korean Journal of Environment and Ecology
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• v.25 no.3
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• pp.421-431
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• 2011

This study examined visitors' perceptions and attitudes about establishing cable car in Mudeungsan Provincial Park (MPP). Data were collected from 401 respondents by a field questionnaire survey in MPP during the September of 2010. 61.7% of respondents opposed to establishing cable car in MPP while 20.6 percent supported it. Respondents showed high level of belief to possible consequences that establishing cable car will result in 'deterioration of ecosystem and natural landscape', 'crowding problem by increased number of visitors', 'disappearance of naturalness or previous nature experiences in MPP'. Respondents, however, presented low belief to 'positive effects on increasing economic income and local economic growth by attracting tourists'. 32.4 percent of the survey respondents evaluated the present MPP as a place of 'Nature Preservation Area (NPA)' and 10.5% as 'Developed Park Area (DPA)'. 48.8% of respondents answered that MPP should be managed as 'NPA' with only 2.5% as DPA. Respondents' socio-demographic characteristics (i.e., gender, age, education level, length of residence in Gwang-ju city), use patterns (number of visits to MPP or to Jungbong and surrounding areas), and normative place condition of MPP showed relationship with the overall support rates about establishing cable car. The results and their implications were discussed.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2003.10a
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• pp.185-185
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• 2003

• Proceedings of the KIEE Conference
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• 2006.07b
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• pp.1187-1188
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• 2006

This paper a new method which applies a genetic algorithm for determining which sectionalizing switch to operate in order to solve the distribution system loss minimization re-configuration problem. In addition, the proposed method introduces a ultra efficient MPP tracking in a solar power generation system.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.18 no.1
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• pp.51-59
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• 2005

SLSV (single loop single vector) method is to solve the excessive computational cost problem in RBDO (reliability-based design optimization) by decoupling the nested iteration loops. However, the practical use of SLSV method to RBDO case is limited by the instability or inaccuracy of the method since it often diverges or converges to a wrong solution. Thus, in this paper, a new modified SLSV method is proposed. This method improves its convergence capability effectively by utilizing Inactive Design and Active MPP Design together with modified HMV (hybrid mean value) method. The usefulness of the proposed method is also verified through numerical examples.

• The Journal of Korean Medicine
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• v.26 no.4
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• pp.74-86
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• 2005

Background: There are increasing neuro-degenerative disorders with aging. Paeoniae Radix(PR) possesses various pharmacological effects such as sedative, analgesic, anti-inflammatory, anti-stress and neuro-protective actions. Also antiaging and anti-cancer effects of PR were reported. Our purpose was to investigate whether PR is useful on the treatment of Parkinson's disease, one of the neuro-degenerative disorders. Objective: We investigated whether Paeonia Radix possesses a protective effect against 1-methyl-4 phenylpyridine(MPP+)-induced cytotoxicity in neuronal cells. Methods: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay, flow cytometry, DNA fragmentation assay, reverse transcription-polymerase chain reaction(RT-PCR), and Western blotting were performed on SK-N-MC neuroblastoma cells. Results: Cells treated with MPP+ exhibited several apoptotic features, while cells pre-treated with Paeonia Radix prior to MPP+ exposure showed s decrease in the occurrence of apoptotic features. Conclusions: These results suggest that Paeonia Radix may exert a protective effect against MPP+-induced apoptosis in SK-N-MC neuroblastoma cells.

• Journal of KIISE:Software and Applications
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• v.32 no.11
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• pp.1013-1020
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• 2005

This paper presents an effective and robust leaf image retrieval system based on shape feature. Specifically, we propose an improved MPP algorithm for more effective representation of leaf images and show a new dynamic matching algorithm that basically revises the Nearest Neighbor search to reduce the matching time. In particular, both leaf shape and leaf arrangement can be sketched in the query for better accuracy and efficiency. In the experiment, we compare our proposed method with other methods including Centroid Contour Distance(CCD), Fourier Descriptor, Curvature Scale Space Descriptor(CSSD), Moment Invariants, and MPP. Experimental results on one thousand leaf images show that our approach achieves a better performance than other methods.