• Parasites, Hosts and Diseases
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• v.56 no.5
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• pp.491-494
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• 2018

Multipurpose contact lens disinfecting solutions (MPDS) are widely used to cleanse and disinfect microorganisms. However, disinfection efficacy of these MPDS against Acanthamoeba cyst remain insufficient. 2, 6-dichlorobenzonitrile (DCB), a cellulose synthesis inhibitor, is capable of increasing the amoebical effect against Acanthamoeba by inhibiting its encystation. In this study, we investigated the possibility of DCB as a disinfecting agent to improve the amoebicidal activity of MPDS against Acanthamoeba cyst. Eight commercial MPDS (from a to h) were assessed, all of which displayed insufficient amoebicidal activity against the mature cysts. Solution e, f, and h showed strong amoebicidal effect on the immature cysts. Amoebicidal efficacy against mature cysts remained inadequate even when the 8 MPDS were combined with $100{\mu}M$ DCB. However, 4 kinds of MPDS (solution d, e, f, and h) including $100{\mu}M$ DCB demonstrated strong amoebicidal activity against the immature cysts. The amoebicidal activity of solution d was increased by addition of DCB. Cytotoxicity was absent in human corneal epithelial cells treated with either DCB or mixture of DCB with MPDS. These results suggested that DCB can enhance the amoebicical activity of MPDS against Acanthamoeba immature cyst in vitro.

• Journal of Oral Medicine and Pain
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• v.8 no.1
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• pp.97-106
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• 1983

A reserch scale of 48 items selected from MMPI by McCall et al. was used to compare psychologic aspects of 80 patients with MPDS to control I subjects and control II subjects. For this, study subjects were selected 80 patients of MPDS who visited the Dept. of Dentistry. K.N.U.H., from December in 1982 to September in 1983. Control I subjects were selected 80 outpatients without MPDS who required dental treatment from December in 1982 to September in 1983. And control II subjects were selected 80 persons without MPDS who required no dental treatment and lived in Taegu. The results were as follow : In study subjects,somatic gruop and behavioral group are markedly high than control (I,II)subjects. In somatic group and behavioral group, there was no significant differencd between control I subjects and control II subjects. In somatics group and begavioral group, there was no significant difference between male and female in each subjects: In study subject, general nature somatic category was higher than head, neck, throat and GIT somatic category.(P<0.05) In study subjects, somatic group and behavioral group gradually increased according to increase in number of MPDS symptom.

• Food Science of Animal Resources
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• v.41 no.5
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• pp.894-904
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• 2021

Microencapsulation is a protective process for materials that are sensitive to harsh conditions encounted during food manufacture and storage. The objectives of this research were to manufacture a milk protein-based delivery system (MPDS) containing Lactobacillus rhamnosus GG (LGG) using skim milk powder and to investigate the effects of manufacturing variables, such as reaction temerpature and holding time, on the physiccohemical properties of MPDS and viability of LGG under dairy food processing and storage conditions. MPDS was prepared using chymosin at varing reaction temperatures from 25℃ to 40℃ for 10 min and holding times from 5 to 30 min at 25℃. The morphological and physicochemical properties of MPDS were evaluated using a confocal laser scanning microscope and a particle size analyzer, respectively. The number of viable cells were determined using the standard plate method. Spherical-shaped MPDS particles were successfully manufactured. The particle size of MPDS was increased with a decrease in reaction temperature and an increase in holding time. As reaction temperature and holding time were increased, the encapsulation efficiency of LGG in MPDS was increased. During pasteurization, the use of MPDS resulted in an increase in the LGG viability. The encapsulation of LGG in MPDS led to an increase in the viability of LGG in simulated gastric fluid. In addition, the LGG viability was enhanced with an increase in reaction temperature and holding time. In conclusions, the encapsulation of LGG in MPDS could be an effective way of improving the viability of LGG during pasturization process in various foods.

• Parasites, Hosts and Diseases
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• v.54 no.6
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• pp.697-702
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• 2016

Acanthamoeba keratitis has been increasing in recent years. Main risk factors are contact lens wear and their cleaning solutions. Most contact lens wearers use multipurpose disinfecting solutions (MPDS) for cleansing and disinfecting microorganisms because of its convenience. We determined amoebicidal effects of MPDS made in Korea and their cytotoxicity on human corneal epithelium cells. Fifteen commercial MPDS (A to O) were tested for their amoebicidal effects on Acanthamoeba castellanii trophozoites and cysts by using a most probable number (MPN) technique. Among them, 7 kinds of MPDS showed little or no amoebicidal effects for 24 hr exposure. Solutions A, B, G, H, L, and O showed positive amoebicidal effects, and solutions M and N killed almost all trophozoites and cysts after 24 hr exposure. However, 50%-N solution showed 56% cytotoxicity on human corneal epithelial cells within 4 hr exposure, and 50%-O solution also showed 62% cytotoxicity on human cells within 4 hr exposure. Solution A did not show any cytotoxicity on human cells. These results revealed that most MPDS made in Korea were ineffective to kill Acanthamoeba. The solutions having amoebicidal activity also showed high levels of cytotoxicity on human corneal epithelial cells. New formulations for improved MPDS that are amoebicidal but safe for host cells are needed to prevent Acanthamoeba keratitis.

• The Korean Journal of Pain
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• v.27 no.1
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• pp.30-34
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• 2014

Background: Myofascial pain dysfunction syndrome (MPDS), otherwise called myofascial pain is one of the most common temporomandibular disorders, which in turn is the most common cause of orofacial pain of non-dental origin. Its etiology is multifactorial and still poorly understood. Psychological factors have been shown to play a role in the etiology. The aim of the study was to evaluate the association between anxiety and salivary cortisol levels in patients with myofascial pain. Methods: Twenty patients suffering from myofascial pain were recruited as the study group. The same number of age and sex matched healthy individuals were taken as the control group. The salivary samples collected between 9-9:15 am from both groups were analyzed for cortisol levels with the competitive enzyme-linked immunosorbent assay method. Anxiety levels of 40 patients were measured using Hamilton's anxiety scale. Results: The mean serum cortisol level of the MPDS group showed a highly significant difference (P < 0.001) from the controls. The mean anxiety scores of the MPDS group showed a highly significant difference (P < 0.001) from the controls. A positive correlation was found between anxiety and the salivary cortisol levels in MPDS patients. Conclusions: These findings suggest that anxiety plays a vital role in the etio-pathogenesis of MPDS; thus, besides pharmacological treatment, psychological support is also needed.

• Proceedings of the Korean Information Science Society Conference
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• 1999.10c
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• pp.700-702
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• 1999

본 논문에서는 개인 휴대통신 시스템에서 다수 기지국에 대해서 동시 진단 및 진단 이력 관리 기능을 가지는 Multi-Position 진단 시스템(MPDS)의 설계 및 구현 방법을 기술하고 앞으로의 발전 방향을 제시한다. MPDS는 Network을 통한 진단 기능의 분산 처리가 가능하고, 그에 따른 진단 결과 Message를 각 Client별로 실시간 분리 전달 기능을 가지며, RDBMS를 이용한 진단 결과 이력 관리 및 Graphic을 사용한 운용자 정합 기능을 수행한다.

• Journal of Oral Medicine and Pain
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• v.7 no.1
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• pp.47-58
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• 1982

The author has studied on the clinical features and symptomatology of 97 MPDS patients, who visited the Dept. of Dentistry, Kyungpook National University, from January to September in 1982. The results were as follow : In age and sex distribution of patients in this population, the third decades appeared to have the highest prevalence and the male to female ratio was almost 1 to 2.23. As to occupation, students and housewives were revealed to have the highest incidence of MPDS. The chief complaints of patients were pains, TMJ noises, and limitation of mouth opening in order of frequency, and the most prevalent site of symptom was that of preauricular area. In symptom sequence, the majority of initial symptoms were TMJ noise and pain but limitation of mandibular movement was progressively developed, regardless of nature of early symptoms. Chronic unfavorable oral habits were found to be the most possible predisposing factors in this study. The average maximum interincisal distance was $38.13\pm10.00mm$ in males and $30.73\pm8.75mm$ in females, and a deviation of mandible during mouth opening was observed in 60.8% of patients. In TMJ signs, tenderness of the TMJ to palpation was found in 60.8% of patients and TMJ noise was audible in 50.5% of patients with a stethoscope. The muscles of masticatory system were palpated according to usual methods, and a significant indidence of muscular tenderness was present, with the lateral pteygoid muscles being most frequently involved, followed by masseter, medical pterygoid and temporalis muscles.

• Journal of Dental Anesthesia and Pain Medicine
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• v.22 no.1
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• pp.19-27
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• 2022

Background: Myofascial pain dysfunction syndrome (MPDS) is the most common type of temporomandibular disorder. This study compared the efficacies of low-level diode laser therapy (LLLT) and laser acupuncture therapy (LAT) in the treatment of MPDS. Methods: This double-blind randomized controlled clinical trial included 24 patients with MPDS who were randomly divided into two equally sized groups. Patients in the LLLT group received 12 sessions of low-level diode laser irradiation applied to the trigger points of the masticatory muscles during 1 month. The same protocol was also used in the LAT group according to the specific trigger points. We measured pain intensity and maximum mouth opening in both groups at baseline, during treatment, and 2 months after treatment completion. Results: The pain intensities decreased from 6.58±1.31 to 0.33±0.65 and from 7.08 ± 1.37 to 0 in the LLLT and LAT groups, respectively. The maximum mouth openings increased from 32.25 ± 8.78 mm to 42.58 ± 4.75 mm and from 33 ± 6.57 mm to 45.67 ± 3.86 mm in the LLLT and LAT groups, respectively. Pain intensity (P = 0.839) and level of maximum mouth opening (P = 0.790) did not differ significantly between the groups. Conclusion: Our results showed similar efficacy between LLLT and LAT in the treatment of MPDS signs and symptoms.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2009.06a
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• pp.731-732
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• 2009

• Journal of Oral Medicine and Pain
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• v.20 no.1
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• pp.79-87
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• 1995

Personality characteristics of third decade female TMD patients was studied by means of SCL-90-R test. 112 TMD patients and 96 dental controls were subjected at the department of Oral medicine, Kyungpook National University Hospital. All the patients were divided into 3 groups according to their pain profile namely, MPDS, ID with Pain and ID with out Pain, and dental controls were divided into 2 groups manely, Dental Controls with Pain and Dental Controls without Pain for comparison. The obtained results were as follows : 1. Mean T-scores of SCL-90-R primary scales and global indexes in the patient and control group were within normal range. 2. When compared between groups with pain, MPDS group were significantly higher in scales of SOM, 0-C, I-S, HOS and PHOB than ID with Pain group and in scales of SOM, I-S. DEP, HOS and PHOM than Dental Controls with Pain group. 3. When compared with ID and Control groups in same pain condition, there were no significant differences between ID without pain and Dental Controls without Pain group. 4. When compared between groups with pain and groups without pain, there were significant differences in scales of SOM and O-C between Dental Controls with Pain and Dental controls without Pain group.