• Title/Summary/Keyword: MP

Search Result 1,991, Processing Time 0.03 seconds

Vasorelaxation Effect of Butanol Fraction of Crataegi Fructus due to LC20 dephosphorylation via increase of Myosin Phosphophatase activity (산사 Butaol 분획이 PGF2$\alpha$-유도 혈관평활근수축의 억제에 미치는 신호전달 연구)

  • Liang Liou Jia;Choi Ho Jeong;Kim Gil-Whon;Shin Heung Mook
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.17 no.2
    • /
    • pp.461-466
    • /
    • 2003
  • The primary mechanism of smooth muscle contraction is phosphorylation of the 20 kDa myosin light chains(LC20) by a myosin light chain kinase(MLCK). Relaxation, then, is generally the result of dephosphorylation of LC20 by myosin phosphatase(MP). Changes in MP activity is one of the important mechanisms in the regulation of Ca2+-sensitivity. Inhibition of MP activity is linked to an increase in phosphorylated myosin light chain(MLC) without an increase in [Ca/sup 2+/]i-levels. It is now generally accepted that Rho-kinase phosphorylates 130 kDa regulatory and myosin binding subunits(M130, MYPT) of MP, which results in an inhibition of MP activity. In addition Rho-kinase can also directly phosphorylate MLC. In the present study, LC20 phosphorylation and MP subunits translocation to the cell membrane were investigated in freshly isolated ferret portal vein smooth muscle single cells treated with PGF2α. We also examined the effect of Y27632(10-5mol/L), Rho-kinase inhibitor, in the MP subunits localization to compare with butanol fraction of Fructus Crataegi in its effect. Butanol fraction of Fructus Crataegi(BFFC; 1㎎/㎖) was more effective in PGF2α induced contraction than those of phenylephrine in its vasodilation effect. It significantly(P<0.05) dephosphorylated the LC20 at time indicated. In addition, the dissociation of subunits are inhibited by BFCF treatment. The results indicate that, in the smooth muscle cells, the relaxation effect of BFFC is associated with increase of MP activity based on inhibition of dissociation of the catalytic and targeting subunits of the phosphatase, and thus decrease the sensitivity of LC20 phosphorylation for Ca/sup 2+/.

An Optimal Algorithm for Stable Marriage Problem (안정된 결혼문제에 대한 최적화 알고리즘)

  • Lee, Sang-Un
    • The Journal of the Institute of Internet, Broadcasting and Communication
    • /
    • v.18 no.4
    • /
    • pp.149-154
    • /
    • 2018
  • There is well known algorithm is a Gale-Shapley algorithm(GSA) for stable marriage problem. The GSA is performed as each man propose to his most favorite woman(MP), then the woman accepts more than one proposal rejects all but her favorite from among those who have proposed to her. This algorithm always gets a stable set of marriages with man-optimal and woman-pessimal. But the woman proposal and man-accept/reject method(WP) is can be get the distinct result. Also, the optimal stable matching may be fail using MP or WP. This paper suggests always get the optimal stable matching on all occasions in order to overcome the shortcomings of MP and WP. The proposed algorithm perform k-opt, k-women exchange with each other for the result of delete at less preference in each woman from MP result. As a result of applied to various experimental data, this algorithm can be get the optimal stable matching that the MP or WP failed to it.

Differential Tolerance of Rice Cultivars to Mesotrione-Contained Herbicides (Mesotrione 함유 제초제에 대한 벼 생태형간 약해반응 차이)

  • Kim, Sang-Yeol;Lee, Ji-Yoon;Yeo, Un-Sang;Oh, Seong-Hwan;Park, Sung-Tae;Lee, Jong-Hee;Jeong, Kuk-Hyun;Cho, Jun-Hyeon;Song, You-Chun;Kang, Hang-Won
    • Korean Journal of Weed Science
    • /
    • v.30 no.3
    • /
    • pp.300-307
    • /
    • 2010
  • Greenhouse experiment was conducted to evaluate tolerance of six rice cultivars, three Indica${\times}$Japonica rice (long grain, cv. Dasanbyeo, Segejinmi and Hanareumbyeo) and three Japonica rice (short grain, Nampyung, Ilpumbyeo and Junamjosaeng) cultivars, to mesotrione+pretilachlor (MP) and bensulfuron-methyl+mesotrione+pretilachlor+pyriftalid (BMPP) in transplanting rice. Two herbicides were applied at 90 g and 180 g a.i. $ha^{-1}$ to three to four leaf stage rice at 5 and 15 days after transplanting, respectively. Related study was also conducted to compare $GR_{50}$ for Indica${\times}$Japonica and Japonica rice cultivars at different MP rates. Response to two herbicides varied with respect to rice cultivars and herbicide rates. All Indica${\times}$Japonica rice cultivars exhibited susceptible to both MP and BMPP as reflected by increased visual injury, shorter plant height and higher plant dry matter reduction when compared with nontreated rice cutlivars. The degree of foliar chlorosis by MP at 90 g a.i. $ha^{-1}$ was 5~6 at 7 days after treatment(DAT) but it was decreased to 3~6 at 14DAT. The degree of leaf chlorosis treated with 180 g a.i. $ha^{-1}$ MP was 6~7 at 7DAT and it was also decreased to 3~8 at 14 DAT. The plant hight of Indica${\times}$Japonica rices was inhibited by 18~43% at application of 90 g a.i. $ha^{-1}$ MP and 30~50% at 180 g a.i. $ha^{-1}$ MP. The dry matter reduction was greater than that of plant height inhibition, showing 46~73% at 90 g a.i. $ha^{-1}$ MP and 65~82% at 180 g a.i. $ha^{-1}$ MP. Similar leaf chlorosis injury and growth inhibition of rice cultivars was observed in the BMPP treatment. The injury and growth inhibition by MP and BMPP increased with increase in herbicide rate from 90 g a.i. $ha^{-1}$ to 180 g a.i. $ha^{-1}$. However, most of the Japonica cultivars are tolerant to MP and BMPP at both rates. There was no visible leaf chlorosis but plant height and dry matter production were slightly reduced at 180 g a.i. $ha^{-1}$. Based on $GR_{50}$ value determined in reduction of shoot dry weight for MP, the Indica${\times}$Japonica rice showed 12.9 fold lower compared with the Japonica rice. The result indicates that rice cultivars vary in tolerance to herbicides of MP and BMPP and Indica${\times}$Japonica rices were more susceptible than the Japonica rices to the MP and BMPP.

The Consumer Acceptance of MP3-playing Clothing and Bio-Signal Sensing Clothing Considered in the Technology Acceptance Model (혁신기술수용모델의 관점에서 고찰한 MP3-playing 의류와 생체신호 센싱 의류의 수용도)

  • Chae, Jin-Mie;Cho, Hyun-Seung;Lee, Joo-Hyeon
    • Science of Emotion and Sensibility
    • /
    • v.12 no.3
    • /
    • pp.289-298
    • /
    • 2009
  • An analysis was carried out for this study to figure out if there exists any differences in the model consumers accept for commercialized MP3-playing clothing and bio-signal sensing clothing. To analyze the differences of the structural variables of the products types, t-test was conducted with SPSS 15.0 package and multi-group analysis with AMOS 5.0 to find out the differences of each path goes with product types in structural equation model. In analytical results of effective sample of 557 copies of questionnaire, consumers' were highly aware of MP3-playing clothing in perceived ease of use, while they were aware relatively high of bio-signal sensing clothing in perceived usefulness, attitudes, consumer acceptance. The perceived value which was input to find out consumers awareness about sale price of commercialized products, was proven to do very important moderating role in forming consumers' attitudes and acceptance intention. Besides, consumers showed a difference in path in accepting model goes with product types. In bio-signal sensing clothing case, 'the perceived usefulness$\rightarrow$attitudes' path which was backed up in MP3-playing clothing was rejected, and 'perceived value$\rightarrow$attitudes' path appeared relatively high with moderating role of perceived value higher than MP3-playing clothing. Considering the results above, as the smart clothing is in the initiative commercialization stage while consumers were in the inquiry stage into awareness or information necessary in the course of purchase decision-making, and so an effective commercialization strategy seems to be necessary.

  • PDF

ISAR Imaging of Airplane-like Targets by Matrix Pencil Method (Matrix Pencil 방법에 의한 비행기 모형의 ISAR 영상화)

  • 유지희;권경일;이용희
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.12 no.2
    • /
    • pp.299-307
    • /
    • 2001
  • This paper presents a experimental study of Inverse Synthetic Aperture Radar(ISAR) imaging using Matrix Pencil(MP) method. A series of measurement for two types of target model was done in a Compact Range(CR)facility. The first target is a set of distributed slim cylinders to get a ISAR image of point-like scatterers. The second is UAV model representing a complex real target. The results show that ISAR images by MP method are better than by conventional FFT method under the realistic measurement conditions.

  • PDF

A Proposal on Analyzing Operational Mission Summary/Mission Profile and RAM Goal Setting from Operational Concepts on the Next-MILSATCOM (차기 군 위성통신체계 OMS/MP 분석 및 운용개념으로부터의 RAM 목표값 산출 제안)

  • Park, Heung-Soon;Kwon, Tae-Wook;Lee, Chul-Hwa;Park, Dae-Hyun
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.16 no.3
    • /
    • pp.295-303
    • /
    • 2013
  • The Operational Mode Summary/Mission Profile(OMS/MP) is a document which describes how a system or training device will be used in wartime and/or peacetime at the time it is field with focus on the future. OMS/MP is also typically used for the RAM goal setting in an early phase of weapon system development. This paper provides OMS/MP and RAM goal of the Next-MILSATCOM which is following military satellite system after ANASIS. We propose operational concepts, user-side OMS/MP model and RAM goal.

Phytochemical Studies on Reynoutriae Radix $('H\check{u}-Zh\grave{a}ng')$

  • Chi, Hyung-Joon;Kim, Hyun-Soo
    • Korean Journal of Pharmacognosy
    • /
    • v.17 no.1
    • /
    • pp.73-77
    • /
    • 1986
  • Anthraquinones, physcion (I), mp $204{\sim}205^{\circ}$ and emodin (II), mp $254{\sim}255^{\circ}$, and $emodin-8-O-{\beta}-{_D}-glucoside$ (IV), mp $191{\sim}192^{\circ}$ together with ${\beta}-sitosterol$ glucoside (III), mp $280{\sim}282^{\circ}$ were isolated from the roots of Polygonum ellipticum Migo and P. sachalinense Fr. Schm. (Polygonaccae). Stilbene derivatives, 3,5,4'-trihydroxystibene (V), mp $258{\sim}260^{\circ}$ and $3,5,4'-trihydroxystilbene-3-O-{\beta}-{_D}-glucoside$ (VI), mp $142{\sim}144^{\circ}$ were also isolated.

  • PDF

Nucleotide Sequence Analysis of Movement Protein Gene from Tobacco Mosaic Virus Korean Pepper (TMV-KP) Strain (담배 모자이크 바이러스 한국고추계통에서 분리한 이동 단백질 유전자의 염기서열 분석)

  • 이재열;정동수;장무웅;최장경
    • Korean Journal Plant Pathology
    • /
    • v.11 no.1
    • /
    • pp.87-90
    • /
    • 1995
  • Complementary DNA of the movement protein (MP) gene of tobacco mosaic virus Korean pepper strain (TMV-KP) was synthesized from purified TMV-KP RNA by using the reverse transcription and polymerase chain reaction (PCR) system. The synthesized double stranded cDNA was cloned into the plasmid pUC9 and transformed into Escherichia coli JM110. The movement protein gene of TMV-KP of the selected clones was subjected to sequence analysis by Sanger's dideoxy chain termination method. The complete sequence of viral MP gene from TMV-KP strain was 807 nucleotides long. The nucleotide of MP gene from TMV-KP has thirteen and two nucleotide differences from TMV vulgarae (TMV-OM) and Korean (TMV-K) strains, respectively. Thus, the nucleotide sequence of TMV-KP MP gene showed higher homology of 99% with that of TMV-K MP gene.

  • PDF

Development of User Interface Design for MP3 CDP based on User Sensibility Evaluation (사용자 감성평가를 통한 MP3 CDP의 사용자 인터페이스 디자인 개발)

  • 박정순;이상화
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
    • /
    • 2002.11a
    • /
    • pp.215-218
    • /
    • 2002
  • 감성정보를 디자인 활동에 필요한 정보로 활용하기 위해서는 전체 디자인 프로세스에서 사용자를 최초 컨셉 단계에서부터 참여시켜 관찰 및 평가에 적극 동참케 하는 사용자 참여 디자인이 매우 효과적이다. 이러한 감성 정보 수집 및 평가를 통한 상용자 인터페이스 디자인 개발 프로세스를 MP3 CDP를 대상으로 적용하여 연구를 진행하였다. 최근의 MP3CD Player들은 일반 음악 CD들이 10여곡에서 많게는 20여곡 정도의 분량을 가지고 있는 것에 비해 그 분량이 최고 100여곡 이상에 이르고 있다. 그럼에도 불구하고 MP3CD Player들은 기존의 일반 음악 CD Player의 UI를 소극적으로 수정, 변경하여 사용하고 있는 상황이다. 본 연구는 자체적인 곡 분류방법을 제시하고 있는 ‘H’사의 MP3CD Player를 선정하고 이를 기준으로 초기 디자인에 사용자를 참여시켜 사용자 감성 정보 및 요소들을 효과적으로 평가하여 사용자 중심 디자인을 극대화 시키는 방법을 모색하였다. 제품의 최초 기능 분석시에는 카드인덱스(Card Index)방식을 이용하여 기능을 그룹핑하고 인터페이스를 개선하였으며 이를 토대로 프로토타입을 완성하였다. 이를 사용자가 직접 조작하는 방식을 관찰 분석하여 평가 결과를 토대로 UI 디자인가이드라인을 제시하였다.

  • PDF

A Wartime·Peacetime OMS/MP Analysis Model for a Naval Ship and Case Study (함정 전·평시 OMS/MP 설정 방법론 연구 및 사례)

  • Ha, Sungchul;Kook, Jungho
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.15 no.5
    • /
    • pp.660-666
    • /
    • 2012
  • The weapon system is getting more and more expensive, complex and smarter. Therefore, efficiently and effectively, it is important to operate the weapon system. OMS/MP is a document to quantify operational factors like as environment, mission, mode etc. It is important data to perform RAM analysis in early weapon development phase and operate better a weapon system. This paper present a process and framework of OMS/MP for a naval ship with a deep analysis of relevant domestic and abroad case studies. It propose OMS/MP analysis framework based on wartime scenario and mission area analysis. This result will contribute not only improvement for the availability of a naval ship but also enhancement of RAM analysis process.