• Title/Summary/Keyword: MMD

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A Recent Update of Clinical and Research Topics Concerning Adult Moyamoya Disease

  • Jeon, Jin Pyeong;Kim, Jeong Eun
    • Journal of Korean Neurosurgical Society
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    • v.59 no.6
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    • pp.537-543
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    • 2016
  • A better understanding of moyamoya disease (MMD), such as natural clinical course, surgical outcomes and research, has been obtained. This review article focuses on an giving an update for adult MMD in the Korean population. In this paper, we mainly discuss the results of our domestic investigations including meta-analysis, and related subjects from other countries.

Recurrent Bleeding in Hemorrhagic Moyamoya Disease : Prognostic Implications of the Perfusion Status

  • Jo, Kyung-Il;Kim, Min Soo;Yeon, Je Young;Kim, Jong-Soo;Hong, Seung-Chyul
    • Journal of Korean Neurosurgical Society
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    • v.59 no.2
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    • pp.117-121
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    • 2016
  • Objective : Hemorrhagic moyamoya disease (hMMD) is associated with a poor clinical course. Furthermore, poorer clinical outcomes occur in cases of recurrent bleeding. However, the effect of hemodynamic insufficiency on rebleeding risk has not been investigated yet. This study evaluated the prognostic implications of the perfusion status during the clinical course of adult hMMD. Methods : This retrospective study enrolled 52 adult hMMD patients between April 1995 and October 2010 from a single institute. Demographic data, clinical and radiologic characteristics, including hemodynamic status using single photon emission computed tomography (SPECT), and follow up data were obtained via a retrospective review of medical charts and imaging. Statistical analyses were performed to explore potential prognostic factors. Results : Hemodynamic abnormality was identified in 44 (84.6%) patients. Subsequent revascularization surgery was performed in 22 (42.3%) patients. During a 58-month (median, range 3-160) follow-up assessment period, 17 showed subsequent stroke (hemorrhagic n=12, ischemic n=5, Actuarial stroke rate $5.8{\pm}1.4%/year$). Recurrent hemorrhage was associated with decreased basal perfusion (HR 19.872; 95% CI=1.196-294.117) and omission of revascularization (10.218; 95%; CI=1.532-68.136). Conclusion : Decreased basal perfusion seems to be associated with recurrent bleeding. Revascularization might prevent recurrent stroke in hMMD by rectifying the perfusion abnormality. A larger-sized, controlled study is required to address this issue.

Resolution of Molecular Species of the Triacylglycerol Containing Petroselinic Acid $(cis-C_{18:1{\omega}12)$ by Silver Ion-HPLC

  • Joh, Yong-Goe;Kim, Seong-Jin
    • Journal of the Korean Applied Science and Technology
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    • v.22 no.4
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    • pp.339-348
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    • 2005
  • On the analysis of triacylglycerol (TG) from the kernels of Acanthopanax sessiliflorus by reversed phase-HPLC, it was separated into three main fractions of PN 44, 46 and 48, according to partition number (PN). On the contrary, it could be clearly classified into seven fractions of SMM, MMM, SMD, MMD, SDD, MDD and MDT by silver ion-HPLC by the number of double bond in the acyl chains of TG species. But resolution of so-called critical pairs of TG molecular species such as molecular pairs of $P_eLL$ $[C_{18:1{\omega}12}/(C_{18:2{\omega}6)2}]$ and OLL $[C_{18:1{\omega}9}/(C_{18:2{\omega}6)2}]$ and OOL $[(C_{18:1{\omega}9)2}/C_{18:2{\omega}6]$, and $P_eP_eL$ $[(C_{18:2{\omega}12)2}/C_{18:1{\omega}6]$ was not achieved $(P_e;$ petroselinic acid, L; linoleic acid, O; oleic acid). On the other hand, TG extracted from Aralia continentalis kernels were also fractionated into seven groups of SSM, SMM, MMM, SMD, MMD, SDD and MDD (S; saturated acid, M; monoenoic acid, D; dienoic acid) by silver ion-HPLC, although it's were classified into three groups of PN 44, 46 and 48 by reversed phase-HPLC. The fractions of SMM, MMM, MMD and MDD were divided into two subfractions, respectively; the fractions of SMM, MMM, MMD and MDD were resolved into the subfraction of $PP_e/P_e$ and POO (critical pairs from each other), that of $P_e/P_e/P_e$ and OOO, that of $P_e/P_e/L$ and OOL, and that of $P_e/L/L$ and OLL.

Preliminary Study of Neurocognitive Dysfunction in Adult Moyamoya Disease and Improvement after Superficial Temporal Artery-Middle Cerebral Artery Bypass

  • Baek, Hyun Joo;Chung, Seung Young;Park, Moon Sun;Kim, Seong Min;Park, Ki Suk;Son, Hee Un
    • Journal of Korean Neurosurgical Society
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    • v.56 no.3
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    • pp.188-193
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    • 2014
  • Objective : Moyamoya disease (MMD) is a chronic cerebrovascular occlusive disease of unknown etiology. In addition, the neurocognitive impairment of adults with MMD is infrequently reported and, to date, has not been well described. We attempted to determine both the neurocognitive profile of adult moyamoya disease and whether a superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis can improve the neurocognitive impairment in exhibiting hemodynamic disturbance without stroke. Methods : From September 2010 through November 2012, 12 patients with angiographically diagnosed MMD underwent STA-MCA anastomosis for hemodynamic impairment. Patients with hypoperfusion and impaired cerebrovascular reserve (CVR) capacity but without evidence of ischemic stroke underwent a cognitive function test, the Seoul Neuropsychological Screening Battery (SNSB). Five patients agreed to undergo a follow-up SNSB test. Data from preoperative and postoperative neurocognitive function tests were compared and analyzed. Results : Five of 12 patients were enrolled. The median age was 45 years (range, 24-55 years). A comparison of preoperative to postoperative status of SNSB, memory domain, especially delayed recall showed significant improvement. Although most of the domains showed improvement after surgery, the results were not statistically significant. Conclusion : In our preliminary study, large proportions of adult patients with MMD demonstrate disruption of cognitive function. This suggests the possibility of chronic hypoperfusion as a primary cause of the neurocognitive impairment. When preoperative and postoperative status of cognitive function was compared, memory domain showed remarkable improvement. Although further study is needed, neurocognitive impairment may be an indication for earlier intervention with reperfusion procedures that can improve cognitive function.

A Study on Visualization of Fine Dust Captured by FOG Droplet (미세액적에 의한 미세먼지 포집 가시화 연구)

  • Oh, Jinho;Kim, Hyun Dong;Lee, Jung-Eon;Yang, Jun Hwan;Kim, Kyung Chun
    • Journal of the Korean Society of Visualization
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    • v.19 no.3
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    • pp.39-45
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    • 2021
  • An experiment to visualize fine dust captured by FOG droplet is conducted. Coal dust with 23.56 MMD (Mean Median Diameter) and water with 17.02 MMD is used as fine dust and FOG droplet. Long distance microscope and high-speed camera are used to capture the images of micro-scale particles sprinkled by acrylic duct. After measuring and comparing the size of the coal dust and FOG droplet to MMD, process to seize the coal dust with FOG droplet is recorded in 2 conditions: Fixed and Floated coal dust in the floated FOG droplet flow. In both conditions, a coal dust particle is collided and captured by a FOG droplet particle. A FOG droplet particle attached at the surface of the coal dust particle does not break and remains spherical shape due to surface tension. Combined particles are rotated by momentum of the particle and fallen.

A Study of Conservative Treatment for Patients with Osteoarthritis of the TMJ (측두하악골관절염 환자의 보존적 치료에 관한 연구)

  • Son, Dae-Eun;Ok, Seung-Joon;Ko, Myung-Yun;Ahn, Yong-Woo
    • Journal of Oral Medicine and Pain
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    • v.32 no.2
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    • pp.227-239
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    • 2007
  • To evaluate the treatment outcome after conservative treatment in patients with osteoarthritis of the TMJ(OA), the subjects were chosen among the patients who presented to the Department of Oral Medicine of Pusan National University Hospital, diagnosed as osteoarthritis of the TMJ, and treated with conservative methods from 1994 to 2006. 101 patients with diagnosis of osteoarthritis of the TMJ were selected as the experimental group and 74 patients with diagnosis of masticatory muscle disorders(MMD) were selected as the control group. Subjective symptoms and clinical findings were investigated to evaluate and compare the subject's status at the first and the last visit. The results were as follows : 1. In the OA group, satisfactory treatment outcome was obtained with conservative methods. But, at the last visit, the symptoms of the OA group were not improved enough compared with those of the MMD group. 2. In the OA group, radiographic findings of panorama view and transcranial projection were positive by about 60 percent. But, computed tomography and single photon emission computed tomography were positive by more than 90 percent. 3. At the last visit of the OA group, the joint noise was reduced significantly. 4. In the majority of the OA group, satisfactory treatment outcome was obtained with conservative methods such as medication, physical therapy, and occlusal stabilization appliance. In the majority of the MMD group, satisfactory outcome was obtained with medication and physical therapy. 5. It took the OA group from 6 months to 2 years to be cured well while the MMD group within 6 months.6. The OA group needed more than 10 times' treatment for satisfactory outcome while the MMD group needed less than 10 times' treatment.

Moyamoya Biomarkers

  • Smith, Edward R.
    • Journal of Korean Neurosurgical Society
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    • v.57 no.6
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    • pp.415-421
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    • 2015
  • Moyamoya disease (MMD) is an arteriopathy of the intracranial circulation predominantly affecting the branches of the internal carotid arteries. Heterogeneity in presentation, progression and response to therapy has prompted intense study to improve the diagnosis and prognosis of this disease. Recent progress in the development of moyamoya-related biomarkers has stimulated marked interest in this field. Biomarkers can be defined as biologically derived agents-such as specific molecules or unique patterns on imaging-that can identify the presence of disease or help to predict its course. This article reviews the current categories of biomarkers relevant to MMD-including proteins, cells and genes-along with potential limitations and applications for their use.

A Study on Comparative Analysis of Maritime Security Programs - Focussed on TWIC

  • Yoon, Dae-Gwun
    • Journal of Navigation and Port Research
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    • v.33 no.4
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    • pp.283-288
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    • 2009
  • To improve maritime security and enhance international shipping commerce within US ports in addition to ISPS (International Ship and Port Facility Security Code), the TWIC (Transportation Worker Identification Credential) program is working on the maritime field from the October 15, 2008 in the United States. In this paper, the program is reviewed and investigated in terms of goal, benefit, solution, and related legislation so forth In addition, other maritime security programs including MMD (Merchant Mariner Document), FAST (Free and Secure Trade), SIDA (Security Identification Display Areas). and Air Cargo security program was analyzed and compared in order to obtain relationship and difference with the program in terms of enrollment frequency, list and method of security check, and profile of each program As a result of this paper, the program is mostly to improve maritime security, protect individual privacy, and enhance commerce rather than other programs.

First Experience: Citizens' Perception, Participation, and Evaluation of the New Legislative Electoral System in Taiwan

  • Yu, Ching-Hsin
    • Asian Journal for Public Opinion Research
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    • v.1 no.1
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    • pp.61-64
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    • 2013
  • In 2008, Taiwan adopted a new mixed member system which is significantly different from the long-implemented SNTV-MMD system for the election of legislators. The new system cuts the number of legislative seats from 225 to 113, extends legislators' terms of office from three years to four, and most importantly, adopts a new mixed-member majoritarian (MMM) electoral system to replace the SNTV system for legislative elections. The election of legislators in 2008 was the first time that this new mixed electoral system was implemented in Taiwan. Mainstream literature continues to discuss the electoral impact on political parties and candidates by the new system while citizens' knowledge of the new system and its concomitant effects on citizens' behavior receive less attention. Worse still, almost all of the literature assumes that voters were fully aware of the operation and impact of the new electoral system and cast their ballots wisely. The purpose of this paper is to explore citizen's perceptions, participation and evaluation of this new system.

A Study on the Mechanical Properties to the Weight Reduction Rate of PET Fabrics(III) (PET직물의 감량율에 따른 역학적 특성변화에 관한 연구(III))

  • 홍성철;이희준;조대현;김승진
    • Textile Coloration and Finishing
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    • v.11 no.1
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    • pp.1-8
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    • 1999
  • This study surveys the mechanical properties such as surface properties(MIU, MMD, SMD) to the weight reduction rate of PET fabrics. For this purpose, 12 kinds of satin and 18 kinds of plain weave fabrics are prepared with change of the physical properties of weft yarn(T.P.M., density, and denier). The weight reduction rate was 0%, 12%, 25%, and 30%. Coefficient of friction(MIU), mean deviation of friction(MMD), and geometrical roughness(SMD) of the fabrics were measured and discussed with wed twist, yarn linear density, weft fabric density and weave structures.

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