• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4323-4326
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• 2016

Background: The cancer mortality-to-incidence ratio (MIR) has been established as an important measure of health disparities in local and global circumstances. Past work has corroborated a linkage between the colorectal cancer MIR and the World Health Organization (WHO) Health System ranking. The literature further documents many Asian countries having incomplete cancer registries and a lack of comprehensive colorectal cancer screening guidelines. Materials and Methods: The colorectal cancer MIR values for 23 Asian countries were calculated from data obtained from the 2012 GLOBOCAN database. The 2000 World Health Organization (WHO) Health System rankings were used as a proxy for health system infrastructure and responsiveness. A regression equation was calculated with the MIR as the dependent variable and the WHO Health System ranking as the independent variable. Predicted MIR values were next calculated based on the regression results. Actual MIR values that exceeded 0.20 from the predicted MIR were removed as 'divergent' points. The regression equation was then re-plotted. Goodness-of-fit for both regressions was assessed by the R-squared test. Results: Asian countries have a relatively wide colorectal cancer MIR range, from a minimum of 0.24 to a maximum of 0.86. For the full dataset, the adjusted R-squared value for this regression was 0.53. The equation was then used to calculate a predicted MIR, whereby two data points were identified as 'divergent' and removed. The adjusted R-squared for the edited dataset increased to 0.66. Conclusions: Asian countries have a marked range in their colorectal cancer MIR values and there is a strong correlationwith the WHO Health System ranking. These results corroborate the contribution of the MIR as a potentially robust tool in monitoring changes in colorectal cancer care for Asian nations.

• Convergence Security Journal
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• v.6 no.1
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• pp.25-32
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• 2006

MIR system is a nationwide medical record information system that makes medical information available to any hospital and health institution at any time, and information in the system mostly requires high security. In particular, personal information related to patients and doctors, medical technology information and each hospital's digital information are used very frequently and are likely to be modified for illegal use. Thus we need to develop a system equipped with security measures to prevent information leakage while providing medical information service effectively.

• Journal of Information Processing Systems
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• v.14 no.1
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• pp.32-55
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• 2018

The digitization of music has seen a considerable increase in audience size from a few localized listeners to a wider range of global listeners. At the same time, the digitization brings the challenge of smoothly retrieving music from large databases. To deal with this challenge, many systems which support the smooth retrieval of musical data have been developed. At the computational level, a query music piece is compared with the rest of the music pieces in the database. These systems, music information retrieval (MIR systems), work for various applications such as general music retrieval, plagiarism detection, music recommendation, and musicology. This paper mainly addresses two parts of the MIR research area. First, it presents a general overview of MIR, which will examine the history of MIR, the functionality of MIR, application areas of MIR, and the components of MIR. Second, we will investigate music similarity measurement methods, where we provide a comparative analysis of state of the art methods. The scope of this paper focuses on comparative analysis of the accuracy and efficiency of a few key MIR systems. These analyses help in understanding the current and future challenges associated with the field of MIR systems and music similarity measures.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7547-7552
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• 2014

The mir-155 family is not only involved in a diversity of cancers, but also as a regulator of the immune system. However, the evolutionary history of this family is still unclear. The present study indicates that mir-155 evolved independently with lineage-specific gain of miRNAs. In addition, arm switching has occurred in the mir-155 family, and alternative splicing could produce two different lengths of ancestral sequences, implying the alternative splicing can also drive evolution for intragenic miRNAs. Here we screened validated target genes and immunity-related proteins, followed by analyzation of the mir-155 family function by high-throughput methods like the gene ontology (GO) and Kyoto Eneyclopedin of Genes and Genemes (KEGG) pathway enrichment analysis. The high-throughput analysis showed that the CCND1 and EGFR genes were outstanding in being significantly enriched, and the target genes cebpb and VCAM1 and the protein SMAD2 were also vital in mir-155-related immune reponse activities. Therefore, we conclude that the mir-155 family is highly conserved in evolution, and CCND1 and EGFR genes might be potential targets of mir-155 with regard to progress of cancers, while the cebpb and VCAM1 genes and the protein SMAD2 might be key factors in the mir-155 regulated immune activities.

• Food Science and Biotechnology
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• v.18 no.5
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• pp.1118-1123
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• 2009

Event-specific real-time polymerase chain reaction (PCR) detection method for genetically modified (GM) maize MIR604 was developed based on integration junction sequences between the host plant genome and the integrated transgene. In this study, 2 primer pairs and probes were designed for specific amplification of 100 and 111 bp DNA fragments from the zSSIIb gene (the maize endogenous reference gene) and MIR604. The quantitative method was validated using 3 certified reference materials (CRMs) with levels of 0.1, 1, and 10% MIR604. The method was also assayed with 14 different plants and other GM maize. No amplification signal was observed in real-time PCR assays with any of the species tested other than MIR604 maize. As a result, the bias from the true value and the relative deviation for MIR604 was within the range from 0 to 9%. Precision, expressed as relative standard deviation (RSD), varied from 2.7 to 10% for MIR604. Limits of detections (LODs) of qualitative and quantitative methods were all 0.1%. These results indicated that the event-specific quantitative PCR detection system for MIR604 is accurate and useful.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.127-127
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• 2010

Owing to many advantages on indirect intersubband absorption from the hole miniband to the electron miniband based on the type-II band alignment in InAs/GaSb strained-layer superlattice (SLS), InAs/GaSb SLS infrared photodetector (SLIP) has emerged as a promising system to realize high-detectivity quantum photodetector operating up to room temperature in the spectral range of mid-infrared (MIR) to far-infrared (FIR). In particular, n-barrier-n (n-B-n) structure designed for blocking the majority-carrier dark current makes it possible for MIR/FIR dual-band SLIP whose photoresponse (PR) band can be exclusively selected by the bias polarity. In this study, we present the MIR and FIR photoresponse (PR) mechanism identified by dual-band PR spectra and photoluminescence (PL) profiles taken from InAs/GaSb SLIP. In the MIR/FIR PR spectra measured by changing bias polarity, each spectrum individually shows a series of distinctive peaks related to the transitions from the hole subbands to the conduction one. The PR mechanism at each polarity is discussed in terms of diffusion current, and a superposition of MIR-PR in the FIR-PR spectrum is explained by tunnelling of electrons activated in MIR-SLS. The effective FIR-PR spectrum decomposed into three curves for HH1, LH1, and HH2 has revealed the edge energies of 120, 170, and 220 meV, respectively, and the temperature variation of the MIR-PR edge energies shows that the temperature behavior of the SLS systems can be approximately expressed by the Varshni empirical equation.

• Korean Journal of Acupuncture
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• v.24 no.4
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• pp.55-67
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• 2007

Objectives : The repeatability and reproducibility of MIR-2, a newly developed impedance measurement device (four electrode method) on skin are of the meridian system, is evaluated and a method to improve the reliability is discussed. Methods : Multiple gage R&R studies were conducted for the impedance measurements over bilateral KI3 acupoint in ten participants by three assessors using MIR-2 device. Gage R&R studies were repeated after controlling the acupoint locating method or one value correction by replacing one assessor's outlying value with an average of the other assessors' values to explore any feasibility of improvement of measurement reliability. Results : Controlling acupoint locating method and replacing one value with an average of other assessors' value led to improved variation metrics in a gage R&R study. Conclusions : Measurement reliability can be improved by controlling measurement procedures or by using repeated measurement method, which will facilitate development of clinically applicable measurement device with reliability.

• Proceedings of the Safety Management and Science Conference
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• 2004.11a
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• pp.253-258
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• 2004

Domestic construction industry (including plant engineering industry) faces severe competition with world-wide leading companies under WTO (World Trade Organization) system. To survive in this competition, domestic construction company should establish and operate standardization system efficiently. In this paper, check list is presented to prepare the efficient reliability management system in domestic construction. And then, the check list is applied in MIR(Maturity Index on Reliability) estimation item to estimate reliability management level of company quantitatively.

• Korean Journal of Remote Sensing
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• v.29 no.1
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• pp.95-104
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• 2013

In this study, a novel method is proposed for retrieving relative surface temperature from single-channel middle infra-red (MIR, 3-5 ${\mu}m$) remotely sensed data. In order to retrieve absolute temperature from MIR data, it is necessary to accommodate at least atmospheric effects, surface emissivity and reflected solar radiance. Instead of retrieving kinematic temperature of each target, we propose an alternative to retrieve the relative temperature between two targets. The core idea is to minimize atmospheric effects by assuming that the differential at-sensor radiance between two targets experiences the same atmospheric effects. To reduce effective simplify atmospheric parameters, each atmospheric parameter was examined by MODTRAN and MIR emissivity derived from ASTER spectral libraries. Simulation results provided a required accuracy of 2 K for materials with a temperature of 300 K within 0.1 emissivity errors. The algorithm was tested using MODIS band 23 MIR day time images for validation. The accuracy of retrieved relative temperature was $0.485{\pm}1.552$ K. The results demonstrated that the proposed algorithm was able to produce relative temperature with a required accuracy from only single-channel radiance data. However, this method has limitations when applied to materials having very low temperatures using day time MIR images.

• Journal of the Korea Safety Management & Science
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• v.6 no.2
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• pp.103-114
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• 2004

IEC 60300 series, the international standards on reliability management system are newly developed and introduced rapidly worldwide. In order to meet this fast-changing situation, it is necessary to apply them to the Korean industries effectively. It includes the establishment of the infrastructure such as documentation of Korean Standards, introduction of test equipments and test manuals, accreditation of the certification bodies and training of the specialists etc. IEC 60300 is upgraded management system of the ISO 9000 and ISO 14000. In this regard, the Korean companies which were certified with the ISO 9000 or 14000 should endeavor to find new strategies and methods to be certified with IEC 60300. This paper introduces a Quantitative method of estimating the level of the reliability management system by applying the MIR(Maturity Index on Reliability) technique. This enables the estimation of the operation level of the system and can upgrade the maturity level of it.