• Journal of the Korea Institute of Military Science and Technology
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• v.22 no.5
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• pp.654-666
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• 2019

The tactical network has several different characteristics compared with commercial internet network such as hierarchical topology, dynamic topology changing and wireless link based connectivity. For considering IP mobility management in the tactical network, current mobility management using Mobile IP(MIP) is not suitable with some reasons such as non-optimal routing paths and single point of failure. Proxy Mobile IP(PMIP) which supporting network-based mobility in hierarchical manner can provide optimal routing path in the tactical network environment, but centralized anchor is still remained a threat to the stability of the tactical network which changes its topology dynamically. In this paper, we propose PMIP-based distributed mobility management for the tactical network environment. From our design, routing paths are always configured in optimized way, as well as path is recovered quickly when the mobility anchor of user is failed. From numerical analysis, comparing to other mobility scheme, result shows that the proposed scheme can reduce packet transmission cost and latency in tactical network model.

• Journal of Korean Neurosurgical Society
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• v.62 no.2
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• pp.153-165
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• 2019

Objective : Spinal cord injury (SCI) is a very serious health problem, usually caused by a trauma and accompanied by elevated levels of inflammation indicators. Stem cell-based therapy is promising some valuable strategies for its functional recovery. Nestin-positive progenitor and/or stem cells (SC) isolated from pancreatic islets (PI) show mesenchymal stem cell (MSC) characteristics. For this reason, we aimed to analyze the effects of rat pancreatic islet derived stem cell (rPI-SC) delivery on functional recovery, as well as the levels of inflammation factors following SCI. Methods : rPI-SCs were isolated, cultured and their MSC characteristics were determined through flow cytometry and immunofluorescence analysis. The experimental rat population was divided into three groups : 1) laminectomy & trauma, 2) laminectomy & trauma & phosphate-buffered saline (PBS), and 3) laminectomy+trauma+SCs. Green fluorescent protein (GFP) labelled rPI-SCs were transplanted into the injured rat spinal cord. Their motilities were evaluated with Basso, Beattie and Bresnahan (BBB) Score. After 4-weeks, spinal cord sections were analyzed for GFP labeled SCs and stained for vimentin, $S100{\beta}$, brain derived neurotrophic factor (BDNF), 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNPase), vascular endothelial growth factor (VEGF) and proinflammatory (interleukin [IL]-6, transforming growth factor $[TGF]-{\beta}$, macrophage inflammatory protein [MIP]-2, myeloperoxidase [MPO]) and anti-inflammatory (IL-1 receptor antagonis) factors. Results : rPI-SCs were revealed to display MSC characteristics and express neural and glial cell markers including BDNF, glial fibrillary acidic protein (GFAP), fibronectin, microtubule associated protein-2a,b (MAP2a,b), ${\beta}3$-tubulin and nestin as well as anti-inflammatory prostaglandin E2 receptor, EP3. The BBB scores showed significant motor recovery in group 3. GFP-labelled cells were localized on the injury site. In addition, decreased proinflammatory factor levels and increased intensity of anti-inflammatory factors were determined. Conclusion : Transplantation of PI-SCs might be an effective strategy to improve functional recovery following spinal cord trauma.

• The Journal of Internal Korean Medicine
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• v.40 no.4
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• pp.567-581
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• 2019

Objective: This study aimed to evaluate the inhibitory effects of SGX01 on the lung injuries of COPD mice model. Materials and Methods: This study was carried out in two ways: in vitro and in vivo. In vitro, L929 cells were challenged with LPS, and then treated with six concentrations of SGX01 (10, 30, 50, 100, 300, and $500{\mu}g/ml$) and analyzed by ELISA. In vivo, C57BL/6 mice were challenged with LPS and cigarette smoking solution (CSS), and then treated with a vehicle only (control group), dexamethasone 3 mg/kg (dexa group), or a SGX01 200 mg/kg (SGX01 group). After sacrifice, the BALF or lung tissue was analyzed with Cytospin, FACS, ELISA, real-time PCR and H&E, and Masson's trichrome staining. Results: SGX01 significantly decreased NO, $TNF-{\alpha}$, and IL-6 on L929 cells challenged with LPS. In the COPD model, SGX01 significantly inhibited the increase of neutrophils, $TNF-{\alpha}$, IL-17A, CXCL-1, MIP2, CD8+ cells in BALF, and $TNF-{\alpha}$, $IL-1{\beta}$ mRNA expression in lung tissue. It also decreased the severity of the histological lung injury. Conclusion: This study suggests the usability of SGX01 for COPD patients by controlling lung tissue injury.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.7
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• pp.236-241
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• 2019

Lumbar stabilization exercise is a popular exercise method in recent clinicians, as it strengthens muscles around the spine and abdominal muscles, but there is a lack of research on the effects of pulmonary function and respiratory pressure. So, this study examined whether abdominal bracing exercise, a typical lumbar stabilization exercise, was effective in pulmonary function and respiratory pressure. In this study, a total of 20's 40 subjects were recruited and randomly divided into an abdominal bracing exercise group(n=20) and control group(n=20). Abdominal exercise group underwent 25 minutes of exercise. Pulmonary function and respiratory pressure values were measured to analyze respiratory function. As a results of the experimental group, there were significant improvements in FVC, FEV1, PEF and MEP(p<.05) and there was a significant difference in the comparison between groups, except the MIP. These results suggest that abdominal bracing exercise can be presented as effective exercises to improve respiratory function.

• Journal of the military operations research society of Korea
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• v.36 no.1
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• pp.15-27
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• 2010

Fire sequencing problem is to find a sequence of firing on the targets. The latest, because the korea artillery force is inferior in number as compared with north korea force. It is an important question to give a fatal damage to the enemy force by using prompt and accurate fire in order to overcome the lack of artillery force. Minimizing the fire finishing time will secure the adapt ability in tactical operation. In this paper, we developed a mathematical model to do allocation the fire on the targets to decrease to total fire operation time. In order to work out the fire sequencing problem, MIP is developed and the optimum solution is obtained by using ILOG OPL. If this analytical model is applied to the field artillery unit, it will improve the artillery fire force enhancement.

• Journal of the Korea Computer Graphics Society
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• v.17 no.1
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• pp.25-31
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• 2011

Photomosaic is a method of representation an input image in forms of mosaics by a set of small tile images. Generally, equal rectangular tiles are used in photo mosaics. Therefore, there are limitations to expression of mosaic according to characteristic of images. In this paper, photo mosaics using quad-tree structure is proposed to create tiles in varies sizes. Initially, color variance per each level of an input image is computed using the mipmap of graphic hardware. Depending on the value of Valiance, the input image is divided into tiles in varies sizes. Each tile finds the most similar reference image and replaces with it. As a result, the method provides another pictorial effectiveness by dividing the input image into tiles in varies sizes depending on color held by the input image. In addition, whole processing is done on the graphic hardware and thereby we achieve faster performance.

• BMB Reports
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• v.44 no.4
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• pp.273-278
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• 2011

Destruction of the skin barrier by thermal injury induces microbial invasion, which can lead to the development of systemic infection and septic shock. Microbial pathogens possess pathogen-associated molecular patterns (PAMPs), which are recognized by conserved receptors. To understand the role of PAMPs in thermal injury-induced mice, LPS or CpG-DNA were topically applied to dorsal skin after thermal injury. We observed an increase in the number of inflammatory cell infiltrates as well as thickening in the dermis upon treatment with LPS or CpG-DNA. We also found that expression of IL-$1{\beta}$, MIP-2, and RANTES induced by thermal injury was enhanced by LPS or CpG-DNA. In addition, the proportions of $CD4^+$ and $CD^8+$ T cells in the spleen and lymph nodes were altered by LPS or CpG-DNA. These results provide important information concerning PAMPs-induced inflammation upon thermal injury and provide a basis for studying the role of PAMPs in thermal injury-induced complications.

• Economic and Environmental Geology
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• v.41 no.5
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• pp.497-507
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• 2008

This study identified and quantified the hidden flows for steel and iron production in Korea using MIPS (Material Input per Service) methodology. In order to estimate the input orientated impact on the environment caused by the manufacture or services of a product, MIPS indicates the quantity of resources used for this product or service. In 2005, 71 million tons of raw materials were used to produce $17.6 million of added value and 4.8 thousand tons of finished steel. The amount of natural resources extracted from natural environments for the purpose of steel production was 245 million tons of TMR(Total Material Requirement), 1524 million tons of water, and 34 million tons of air. The material intensities for steel production by natural inputs (raw materials and energy) was 4.3 ton/ton of TMR, 28 ton/ton of water, and 0.5 ton/ton of air.

• The Journal of the Acoustical Society of Korea
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• v.20 no.7
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• pp.63-68
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• 2001

This paper describes the details of ITU-T SGIS G.729A speech coder implementation using ARM9 Thumb/sup R/ processor core and various techniques used in the optimization process. ITU-T G.729 speech coder is the standard of the toll quality 8 kbit/s speech coding. The input to the speech encoder is assumed to be a 16 bits PCM signal at a sampling rate of 8000 samples per second. G.729A is reduced complexity version of the G.729 coder. This version is bit stream interoperable with the full version. The implemented coder requires 34.8 MIPS for the encoder and 8.1 MIPS for the decoder, 36.5 kBytes of program ROM and 6.3 kBytes of data RAM, respectively. The implemented coder is tested against the set of 9 test vectors provided by ITU-T for bit exact implementation.

• Journal of Magnetics
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• v.19 no.4
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• pp.365-371
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• 2014

The aim of this study was to evaluate the utility of 3-D images by comparing and analyzing reconstructed 3-D images from fast spin echo images of MRI cholangiopancreatography (MRCP) images using maximum intensity projection (MIP) with the subtraction images derived from dynamic tests of magnetic resonance mammography. The study targeted 20 patients histologically diagnosed with pancreaticobiliary duct disease and 20 patients showing pancreaticobiliary duct diseases, where dynamic breast MR (magnetic resonance) images, fast spin echo imaged of pancreaticobiliary duct, and 3-D reconstitution images using a 1.5T MR scanner and 3.0T MR scanner were taken. As a result of the study, the signal-to-noise ratio in the subtracted breast image before and after administering the contrast agent and in the reconstructed 3-D breast image showed a high ratio in the reconstructed image of lesional tissue, relevant tissue, and fat tissue. However, no statistically meaningful differences were found in the contrast-to-noise ratio of the two images. In the case of the MRCP image, no differences were found in the ratios of the fast spin echo image and reconstructed 3-D image.