• 한국통신학회논문지
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• 제25권5B호
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• pp.985-991
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• 2000

본 논문에서는 인덕터의 면적을 극소화시키고 인덕턴스와 Q값을 극대화시키기 위한 최적구조의 2GHz 자성박막 인덕터를 설계하고 제작하였다. Eddy-current 표피효과를 위해서 Co90Fe10와 SiO2의 multilayer를 사용하고, multilayer를 적용한 새로운 lumped 소자모델을 고려하여 최적설계를 수행하였다. 2GHz에서 동작하는 새로운 자성박막 인덕터는 photo-lithography와 lift-off기술을 이용하여 Si 기판위에 제작되었다. 50개 이상의 동일한 인덕터들의 주파수 특성은 RF Impedance Analyzer로, 자기공진주파수는 Vector Network 분석기(HP8510)로 측정되었다. 개발된 인덕터들은 1.8~2.3GHz 범위의 자기공진주파수, 47~68nH 범위의 L값, 그리고 1GHz이상의 주파수에서 70~80정도의 Q값을 가지므로 L과 Q가 극대화된 아주 우수한 최적구조의 소형(면적=30.8$\times$30.8mil2) 박막인덕터가 성공적으로 제작되었다.

• Journal of Microbiology
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• 제44권6호
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• pp.641-648
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• 2006

We previously reported that Skp1, a component of the Skp1-Cullin-F-box protein (SCF) complex essential for the timely degradation of cell cycle proteins by ubiquitination, physically interacts with Bfa1, which is a key negative regulator of the mitotic exit network (MEN) in response to diverse checkpoint-activating stresses in budding yeast. In this study, we initially investigated whether the interaction of Skp1 and Bfa1 is involved in the regulation of the Bfa1 protein level during the cell cycle, especially by mediating its degradation. However, the profile of the Bfa1 protein did not change during the cell cycle in skp1-11, which is a SKP1 mutant allele in which the function of Skp1 as a part of SCF is completely impaired, thus indicating that Skp1 does not affect the degradation of Bfa1. On the other hand, we found that the skp1-12 mutant allele, previously reported to block G2-M transition, showed defects in mitotic exit and cytokinesis. The skp1-12 mutant allele also revealed a specific genetic interaction with ${\Delta}bfa1$. Bfa1 interacted with Skp1 via its 184 C-terminal residues (Bfa1-D8) that are responsible for its function in mitotic exit. In addition, the interaction between Bfa1 and the Skp1-12 mutant protein was stronger than that of Bfa1 and the wild type Skp1. We suggest a novel function of Skp1 in mitotic exit and cytokinesis, independent of its function as a part of the SCF complex. The interaction of Skp1 and Bfa1 may contribute to the function of Skp1 in the mitotic exit.

• Reproductive and Developmental Biology
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• 제32권4호
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• pp.217-222
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• 2008

The techniques of IVM, IVF and IVC of canine oocytes may provide useful information for gamete salvage programs and the conservation of endangered canidae. This investigation has been made to determine the efficiency of in vitro maturation (IVM) as a basic experiment to study the development of canine oocytes after in vitro fertilization (IVF). The rate of oocytes developing to the Mil stage was higher in the hormone treated group (10 IU/ml hCG+eCG, 14.7%, p<0.05) than in the control group (0 IU/ml hCG+eCG, 10.0%). The monospermy and pronuclear rates of canine oocytes were investigated after caffeine treatment on IVF. Canine oocytes were fertilized in the Fert-TALP medium supplemented with 0, 10, 20 or 30 mM caffeine (Fert I, Fert II, Fert III or Fert IV, respectively). The highest pronuclear formation rate was obtained in the Fert I for 24 h IVF (6.7%, 6/89). Therefore, it is believed that unlike in other mammals, caffeine in canine IVF does not increase the efficiency of fertilization rate, and is not an important factor.

• Clinical and Experimental Reproductive Medicine
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• 제27권4호
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• pp.387-392
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• 2000

Objectives: 1) To compare the efficacy of urofollitropin (Follimon) to that of recombinant human FSH (rhFSH) on the growth and maturation of mouse early preantral follicles in vitro, and 2) effect of vitrification on the growth and maturation of preantral follicles and oocytes . Methods: Isolated early preantra1 follicles (100-130 ${\mu}m$ diameter) were cultured for 12 days in 20 ${\mu}l$ ${\alpha}$-MEM media drop under the mineral oil. Follimon or rhFSH was added to the culture medium at various concentrations (0, 10, 100, and 1000 mIU/ml). Results: With Follimon, the dose of 10 mIU/ml showed the best follicle survival, growth, and MIl rate of oocyte than the other concentrations. Whereas the optimal dose of rhFSH was 100 mIU/ml. Despite the different optimal doses, the efficacy of two different FSHs on the follicle growth and maturation was similar. Isolated mouse preantral follicles were cryopreserved by vitrification and cultured in vitro for 12 days with 100 mIU/ml rhFSH. Despite the decreased follicular survival rate after thawing, the follicular growth and maturation rate of its oocyte were comparable to those of the fresh follicle. Conclusion: Results from the present study revealed that 1) the optimal doses of Follimon and rhFSH for in-vitro culture of mouse follicles are different, and 2) the frozen-thawed follicles develop normally after vitrification.

• 치과방사선
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• 제27권2호
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• pp.91-103
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• 1997

The purpose of this study was to aid in the prediction of tumor cell tolerance to radiotherapy and/or chemotherapy. For this study, cell surviving curves were obtained for human epidermoid carcinoma A-253 cell line using semiautomated MTT assay. 2,4,6,8,10 Gy were irradiated at a dose rate of 210 cGy/min using /sup 60/Co Irradiator ALDORADO 8. After irradiation, A-253 cell lines(2×10⁴cells/mil were exposed to bleomycin or cisplatin for 1 hour. The viable cells were determined for each radiation dose with/without 2 /lg/mi of drug at the 3rd day. And they were compared to control values. The results were obtained as follows : 1. The surviving curve with gentle slope was obtained after irradiation of 2, 4, 6, 8, 10 Gy on A-253 cell line. 2. The cytotoxicity of bleomycin or cisplatin at the concentration of 2㎍/ml was great on A-253 cell line. But, there was no significant difference between the cytotoxicity of bleomycin and that of cisplatin. 3. There were significant differences of surviving fractions after irradiation with 2㎍/mi of bleomycin compared with irradiation only on A-253 cell line. 4. There were significant differences of surviving fractions after irradiation with 2㎍/ml of cisplatin compared with irradiation only on A-253 cell line. 5. There were no significant differences of surviving fractions between the groups of irradiation with bleomycin and the groups of irradiation with cisplatin on A-253 cell line.

• 광물과산업
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• 제27권
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• pp.8-15
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• 2014

본 연구에서는 법정광물 및 정부비축광물을 대상으로 HSK Code 개정(안)을 수립하였다. 법정 광물 중 리튬 광, 희토류 광, 사문석, 연옥, 비축 대상 광종 중 인듐 괴, 페로텅스텐, 안티모니 괴, 셀렌 그래뇰, 갈륨, 산화란탄, 탄산세륨 등의 경우 타 품목과 혼합되어 HSK Code가 부여되어있어 세부 품목별로 정확한 무역통계를 파악하기가 어렵다. 또한 현재의 HSK Code 분류체계에서는 대략적인 품목의 명칭 정도만을 확보할 수 있을 뿐 용도, 규격, 성분, 타입 등 보다 구체적인 품목에 대한 정보는 확보하기가 어려운 상황이다. 법정광물, 정부비축 등 국가적 차원에서 관리되고 있는 광물자원에 대해서는 정확한 통계적 데이터 구축을 위해 품목분류를 세분화하여 단독으로 HSK Code를 관리하는 것을 원칙으로 하였다. 단, 국제 공통기준(HS Code 6단위)을 준수하는 범위 내에서 개정안을 마련하였으며, 수입규모가 일정규모 이상(금액기준 : 5천만불 이상, 물량기준 : 5천톤 이상)인 품목을 개정 대상으로 선정하였고 HSK Code간 Hierarchy의 균형을 고려하였다.

• 한국산학기술학회논문지
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• 제13권10호
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• pp.4418-4425
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• 2012

현재의 국내 군수 환경은 운용단계에 있는 무기체계에 대해 PBL 개념의 적용이 확대되고 있는 추세이다. 본 연구에서는 전수명주기에 걸쳐 PBL 적용 프로세스와 ILS 요소 개발을 모델링 해 봄으로써 PBL 적용 프로세스의 개선안을 도출하려고 한다. 특히 개발초기 단계부터 PBL 적용 프로세스를 모델링 해 봄으로써 개선을 도모하였다. 또한, ILS 개발 시점부터 PBL 개념이 반영되도록 ILS 요소 개발과의 상관관계를 설정함으로써 운용단계에 있는 체계가 아닌 개발단계부터 ILS 개발절차에 PBL을 고려하는 개선방안을 제공한다. 기존에 국내에서 적용 중인 PBL 개념이 ILS의 보급체계와의 연계성에만 국한된 개념이라면 이를 확장해서 개발체계 전체의 가용도, 신뢰도, 군수지원 비용 등을 고려한 개선된 PBL 적용이 가능하다.

• Journal of Acupuncture Research
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• 제20권5호
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• pp.28-37
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• 2003

Objective & Methods: In order to ascertain the names. locations. the way of getting acu-point and indications for moxibustion about Ko-Hwang(膏盲) and Go-Hwang-Su(膏盲兪). I have translated the text for Ko-Hwang(膏盲) and Go-Hwang-Su(膏盲兪) collected in several relative classical books. and performed literal investigation about it. Through the study, the following results are obtained. Results & Conclusions: 1. The two words Go(膏) and Hwang(盲) have different concepts each other originally. and Go-Hwang(膏盲) is the abbreviation of the words "Upon the Hwang(盲), Under the Go(膏)", which means "A gap of Heart and diaphragm" that is under the heart and on the diaphragm 2. Go-Hwang-Su(膏盲兪) is the acu-point which can treat the diseases located in the gap of Go(膏) and Hwang(盲), so they must not be named as Go-Hwang(膏盲) or Go-Hwang-Hyui(膏盲穴). 3. The origination of Go-Hwang-Su(膏盲兪) is speculated as the interval of Hwang-Bo-Mil(皇甫謐) and Son-Sa-Mak(孫思邈). And I think it had been created by Son-Sa-Mak(孫思邈) up to now. 4. The words "Four ribs and Three spaces(四肋三間)" those are founded in the text of The Entrance of Medicine(醫學入門) and The Great Success on Acupuncture and Moxibustion(針灸大成) are either the words those had been quoted from The Bible of Helping Life by Acupucture and Moxibustion(針灸資生經) in wrong way. or the misunderstanding of the original mind of Son-Sa-Mak(孫思邈) as being quoted in the text. So you should know it exactly as Son-Sa-Mak(孫思邈) had said. 5. When you search the acu-point Go-Hwang-Su(膏盲兪), you must pull the arms of patients forwardly to reveal the acu -point. because it is covered by the scapula in normal posture. 6. The indications for the use of Go-Hwang-Su(膏盲兪) are same as mentioned in this study. And it can grow the Yang-Gi(陽氣) more prosperous.

• 한국군사과학기술학회지
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• 제20권1호
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• pp.1-11
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• 2017

In this paper, design requirements of the large radar were investigated, and development was performed through the analysis and design. Large radar should be designed by bearing the 75 knot wind force and $20kg/m^2$ ice mass as operating conditions in order to meet structural stability, and driving torque and bearing load were calculated for securing the driving stability. Thermal dissipation analysis was performed considering TRM and DC-DC Converter's limitation temperature by $50^{\circ}C$ ambient temperature condition in order to attain thermal stability, and PSD and shock analysis were carried out by using MIL-STD-810G vibration and shock specification in order to transport and installation of the large radar. As a result, all components of large radar could secure the structural stability more than 2.8 factor of safety, and driving stability was also secured with adequate bearing fatigue life. Thermal stability was attained by allowable max temperature 88.7 C of the TRM, and structural stability for transportation and installation of the large radar was also secured more than 5 factor of safety. After it was transported and installed to the radar site, operating capability was finally verified by rotating the large radar.

• 한국항공우주학회지
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• 제32권3호
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• pp.82-87
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• 2004

항공기 구조 개발에 관련된 MlL-HDBK-1530 에는 구조 건전성을 확보하기 위한 요구사항이 기술되어있다. 기체 구조의 내구성 및 손상허용성은 요구항목 중의 하나로서 관련 규격서의 요구조건과 절차에 따라 해석 및 시험을 통하여 입증되어야 한다. 본 논문에서는 T-50 항공기 (고등 훈련기)의 안전성 및 내구성 평가를 위한 전기체 내구성 시험하중 설계에 대하여 기술하였다. 내구성 시험하중 설계는 대한민국 공군과 미군사규격서의 요구조건 및 절차에 따라 수행되었다. 실제 비행상태 구현을 위한 전기체 부유식 시험조립 기법과 비행대비행 하중 스펙트럼의 모든 하중을 정확하게 모사 할 수 있는 시험 하중 최적화 기법 및 6-자유도 평형기법을 개발하여 적용하였다. 개발된 기법은 향후 항공기 전기체 구조시험을 수행하는데 있어서 유용한 시험하중 설계 기법임을 확인하였다.