• IMMUNE NETWORK
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• 제1권2호
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• pp.135-142
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• 2001

Background: A large number of diseases occur in association with specific HLA-B or-C alleles. Recently a new gene, termed maj or histocompatibility complex class I chain-related gene A (MICA), has been identified in close proximity to HLA-B. The function of this gene is still unknown. However, it is structurally similar to HLA class I genes. MICA gene is polymorphic and is potentially associated with several diseases. Methods: To evaluate the association of MICA gene in Korean patients with human immunodeficiency virus 1 (HIV-1) infections, Polymerase chain reaction-Sequence specific primer (PCR-SSP) was done for MICA alleles in the extracellular exons, and a microsatellite analysis for GCT repeat polymorphisms in the TM exon was also completed. Results: In 199 Korean healthy controls, 7 alleles were observed and the frequencies for each allele were MICA008 (44.7%), MICA0 10 (34.2%), MICA002 (31.7%), MICA004 (23.6%), MICA0 12 (2 1.6%), MICA009 (19.6%), and MICA007 (6.5%). When 65 HIV seropositive patients were analyzed, MICA007 allele frequency was significantly higher than in controls (15.4% vs 6.5 %, RR=2.6, p<0.04). In contrast, the frequencies of other MICA alleles and microsatellite alleles in the transmembrane region of MICA gene were not significantly different between HIV seropositive patients and controls. The tight linkage between MICA alleles in the extracellular exons and GCT repeat polymorphisms in the TM exon was observed as follows; MICA002/A9, MICA004/A6, MICA007/A4, MICA008/A5.1, MICA0 10/A5, and MICA0 12/A4 in both groups. No significant difference between patients and controls was observed in the haplotype frequencies of MICA alleles in the extracellular exons and GCT repeat polymorphisms in the TM exon. Conclusion: The data suggest that immune functions related with MICA gene may affect a HIV infections.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2004년도 추계학술대회논문집
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• pp.58-64
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• 2004

The shrinkages of injection molded parts are different in molding operational conditions, resins and additives. The shrinkage of injection molded part for crystalline polymer, PBT (polybutylene terephthalate) has been studied for various operational conditions of injection molding and content of additives. Mica was used as a additive to PBT to examine the part shrinkage according to the mica content. The part shrinkages of mica contained PBT decreased as mica content increases. Higher injection temperature and injection pressure resulted in a lower shrinkage. As mold temperature increases the part shrinkage decreased. The part shrinkage of flow direction was less than that of the perpendicular direction to the flow for both pure and mica contained PBT. However the shrinkage difference between flow and perpendicular to flow directions decreased as mica content increased.

• 한국재료학회지
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• 제23권12호
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• pp.672-679
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• 2013

$Fe_4[Fe(CN)_6]_3$ coated on a mica or $TiO_2$/mica surface as infrared reflective blue pigment was prepared by a hydrothermal method. $Fe_4[Fe(CN)_6]_3$, used as coloring agent, was uniformly coated on mica or $TiO_2$/mica under the optimized condition of a 1.2 : 1 weight ratio between iron(III) chloride hexahydrate and potassium ferrocyanidetrihydrate at the initial pH level of 4.5 at $70^{\circ}C$. The infrared (IR)-reflective pigments were characterized by SEM, Zeta-potenial, FT-IR, and UV-VIS NIR spectrophotometry. Especially the CIE color coordinate and total solar reflectance(TSR) properties of the pigments were investigated in relation to variation of the coating and coated substrate thicknesses. Isolation-heat paint was prepared with 20 wt% blue pigments fully dispersed in acryl-urethane resin and several additives to coat the film uniformly. The films were also measured with CIE color coordinate, TSR, and the surface temperature was recorded by an isolation-heat measuring system. The pigments and films of $Fe_4[Fe(CN)_6]_3$ coated on mica and $TiO_2$/mica showed high TSR values compared with the TSR value of $Fe_4[Fe(CN)_6]_3$ itself. According to the increase of TSR value, the property of isolation-heat is effective. To realize the optimal blue color, we applied the the pigment to $TiO_2$ coated mica(TM(b)) which has blueish interference color. The pigment of $Fe_4[Fe(CN)_6]_3$ coated on TM(b) shows a strong blue color compared with that of $Fe_4[Fe(CN)_6]_3$ coated on $TiO_2$/Mmca(TM(w)), which has a whitish interference color.

• 한국주조공학회지
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• 제17권6호
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• pp.569-576
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• 1997

Coating materials for Evaporative Pattern Casting (EPC) process have been developed to investigate the effect of refractories on coating material properties. Three types of developed and one foreign coating materials were used. The former designated as A, B, C and the latter named S.K. The refractory of coating material A is spherical shape of zirconia, and the ones of B, C and S.K. is flake shape of mica. Strength, permeability at room and elevated temperature, anti-sand attachability and carbon residuary were evaluated at each coating materials. Permeability measurement device for elevated temperature was also designed. The zirconia type of coating material had excellent permeability, on the other hand the mica type had good strength and anti-sand attachability. It was found that the refractories were not broken during casting, so permeability indicated same trend at both room and elevated temperature. Based on results, coating material contained small size of mica which is designated as B has the best combination for cast iron.

• 대한화장품학회지
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• 제24권3호
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• pp.51-58
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• 1998

Generally pigment differs from dye stuff because it cannot be melted in water but also because it is stable physically and chemically. In this study you will discover the function, properties and effects of Micai-TiO$_2$-SiO$_2$pigment as abase material pigment. But until now used Mica of the base material is about 7-l5${\mu}{\textrm}{m}$ with an average diameters of 15${\mu}{\textrm}{m}$. A new characteristic superficial pigment was obtained from covering the TiO$_2$ and SiO$_2$ with the adsorption result of isoelectric point of a Mica flake, TiO$_2$ and SiO$_2$In the composition reaction study of adsorption was done as well as the physical characteristics of the superficial texture of the obtained material. L,a,b of color change as oil was absorbed, optical nature and change of reflection according to direct and diffused reflection. In the composition of Mica slurry the best result obtained was in a solution with pH 2.0 to 2.3. Following this result, we can come to the idea that electrical attraction was done during the change of electrical charge of the Mica and TiO$_2$ deposit. Also this pigment shows a big scale between the direct reflection and diffused reflection light. Using this characteristic in cosmetic, it was obtained a natural but a contrast between light and shadow making possible a sculptured make-up. Color change due to oil adsorption was insignificant which improved the last of make up.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.1151-1154
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• 2005

The size effects for adhesive and frictional characteristics were studied. The specimen was Mica and the AFM tips were SiO2. The radii of SiO2 tip were 280, 380, 930, and 2230 nm on which tribological tests had never been performed. It was found that the adhesive forces and the frictional coefficients increased non-linearly with tip radius. Compared with previous studies at nanoscale and microscale, the results showed behaviors bridging each previous result. It could be said that these results were clues to explain the material behaviors between nanoscale and microscale both in adhesion and friction.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.4039-4044
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• 2014

Background: The aim of this study was to investigate the anti-cancer effects and mechanisms of immunochemotherapy of 5-fluorouracil (5-FU) and interleukin-2 (IL-2) on non-small cell lung cancer (NSCLC) A549 cells. Materials and Methods: In order to detect whether 5-FU+IL-2 could effectively inhibit tumor growth in vivo, we established an A549-bearing nude mouse model. The cytotoxicity of natural killer (NK) cells was evaluated using a standard chromium release assay. To evaluate the relevance of NK cells in 5-FU+IL-2-mediated tumor inhibitory effects, we depleted NK cells in A549-bearing mice by injecting anti-asialo-GM-1 antibodies. Effects of 5-FU+IL-2 on the expression and promoter activity of NKG2D ligands (MICA/MICB) in A549 cells in vitro were also assessed. Results: In A549-bearing nude mice, combination therapy significantly inhibited tumor growth in comparison with monotherapy with 5-FU or IL-2 and enhanced the recognition and lysis of tumor cells by NK cells. Further study of mechanisms showed that NK cells played a vital role in the anticancer immune response of 5-FU+IL-2 immunochemotherapy. In addition, the combination therapy synergistically stimulated the expression and promoter activity of MICA/MICB. Conclusions: 5-FU and IL-2 immunochemotherapy significantly inhibited tumor growth and activated NK cytotoxicity in vivo, and these effects were partly impaired after depleting NK cells in tumor-bearing mice. Combination treatment of 5-FU and IL-2 upregulated the expression and the promoter activity of MICA/MICB in A549 cells, which enhanced the recognition of A549 cells by NK cells. All of the data indicated that immunochemotherapy of 5-FU and IL-2 may provide a new treatment option for patients with lung cancer.

• 동아시아식생활학회지
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• 제14권5호
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• pp.513-518
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• 2004

The effect of polyethylene film(PE) packaging of golden mushroom wrapped with Korean paper containing 20% mica powder on the changes in weight, color, texture, PPO activity, number of total microbe(TM) and sensory quality during storage at 10℃ were investigated. The experiments were divided to 3 groups(control; only PE packaging, KP; PE packaging wrapped with Korean paper up and down of the sample, KPM; PE packaging with Korean paper containing 20% mica powder up and down of the sample). The weight of the mushroom in the KPM was the lowest until 9 days-storage, but the weight was the highest at 15 days-storage, showing 12.5% higher against the initial weight. L* values of the mushrooms in the control and KP treatment were decreased, but the value in the KPM treatment was maintained as the same of the initial value during storage. The increasing rate of a* and b* values in the all plots during storage was the lowest in KPM and in order of KPM

• 정보보호학회논문지
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• 제18권5호
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• pp.3-16
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• 2008

무선 센서 네트워크는 센서 노드 또는 모트(mote)라 불리는 소형 장치들로 이루어진 무선 네트워크이다. 최근 센서 네트워크에 대한 연구가 활발한 가운데 센서 네트워크에서의 보안에 관한 연구 또한 활발히 진행되고 있다. 센서 노드 및 센서 네트워크 상의 정보를 안전하게 저장, 전송하기 위해서는 암호 알고리즘의 구현이 필요하며, 이 암호 알고리즘들은 센서 노드의 한정된 자원을 효과적으로 활용할 수 있도록 효율적인 구현이 필수적이다. 센서 노드 상에서 이용될 수 있는 암호로는 TinyECC 등의 공개키 암호와 AES와 같은 표준 블록 암호가 있으나, 스트림 암호는 최근에서야 eSTREAM 프로젝트에서 표준화가 완료되어 아직 센서 노드상에서 사용 가능성이 명확하지 않은 실정이다. 이에 본 논문에서는 eSTREAM의 2단계와 3단계에 채택되었던 10개 소프트웨어 기반 암호들 중 9개의 암호들을 MicaZ 모트 상에 구현하여 성능을 비교하고, 특히 최종적으로 eSTREAM에 채택된 SOSEMANUK, Salsa20, Rabbit을 포함한 6개 암호에 대해서는 MicaZ에 적합하도록 최적화하였다. 또한 참조 구현으로써 하드웨어용 스트림 암호 및 AES-CFB에 대한 실험 결과도 제시한다. 본 논문의 실험에 따르면, 대부분의 스트림 암호가 약 31Kbps - 406Kbps의 암호화 성능을 보임으로써 센서 노드에서 사용하기에 큰 무리가 없음을 확인할 수 있었다. 특히 최종적으로 채택된 SOSEMANUK, Salsa20, Rabbit의 경우 센서 노드에 적합한 128바이트 크기의 작은 패킷의 암호화에서 각각 406Kbps, 176Kbps, 121Kbps의 속도를 보여주고, 70KB, 14KB, 22KB의 ROM및 2811B, 799B, 755B의 RAM을 사용함으로써, 106Kbps의 속도를 보여준 소프트웨어 기반 AES에 비해 우수한 성능을 보임을 알 수 있었다.

• 전기의세계
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• 제18권2호
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• pp.15-20
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• 1969

The main focus of this paper is on the study of the .gamma. ray irradiation effect upon the electrical properties of a B-kind insulator which is one of the inorganic insulators. The mica is so typical of the B kind insulators as to be selected for a sample. DC, AC, and Impulse voltage is applied to the variable .gamma. ray irradiated dose samples with the constant time duration and the time variable samples with the .gamma. ray irradiated dose. The dielectric breakdown voltage and dielectric constant are measured from the samples and we get the experimental data that the dielectric breakown voltage variations are relatively large, but the dielectric constants are almost constant. The above conclusion is useful for the selection and application of the inorganic insulators under the irradiation effects, and we expect that the conclusion can apply to not only B-kind insulators but also the inorganic insulators.