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Effects of Compression Stimulation Application on Cell Proliferation in the Hippocampal Dentate Gyrus of the Sprague-Dawley Rats (흰쥐 해마의 치상회에서 압박자극 적용이 뇌 신경세포 증식에 미치는 영향)

  • Yu, Byong-Kyu;Kim, Kyeong-Mi;Kim, Chang-Ju
    • The Journal of Korean Academy of Sensory Integration
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    • v.2 no.1
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    • pp.21-32
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    • 2004
  • Objective : Effect of treadmill exercise on hippocampal neural cell proliferation under normal conditions and alcohol intoxication conditions has been recently studied; however, this effect under sensory stimulation application has not clarified yet. In the present study, the effect of compression stimulation application on hippocampal neural cell proliferation in the dentate gyrus in normal and alcohol intoxicated rats was investigated. Methods : Experimental design: comparative investigation on number of 5-Bromo-2'-deoxyuridine(BrdU)B-positive cells in dentate gyrus 5 days after commencement. Setting: animal laboratory. Participants: male Sprague-Dawley rats of 3weeks old in age weighing $80{\pm}10gm$. Intervention: animals were randomly assigned into 4 groups; control-rest group(n=8), control-compression group(n=8), alcohol intoxication-rest group(n=8) and alcohol intoxication-compression group(n=8). Animals of the alcohol intoxicated groups were injected intraperitoneally with alcohol(2g/kg) twice per day for 3 days. All animals were injected BrdU(50mg/kg) intraperitoneally, and rats compression stimulation application groups were compressed using sphygmomanometer cuff times per day, for 5 days following alcohol administration. Measures: mean number of BrdU-positive cells in dentate gyrus was observed via immunohistochemistry. Results : Compression stimulation application significantly increased the number of BrdU-positive cells in the dentate gyrus. Also, treatment with alcohol for 3 days inhibited cell proliferation, and compression stimulation application alleviated alcohol-induced inhibition of new cell formation. Conclusion : These results suggest the possibility that compression stimulation application may help in improvement following alcohol-induced brain damaged.

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An Experimental Study on the Degree of Phonetic Similarity between Korean and Japanese Vowels (한국어와 일본어 단모음의 유사성 분석을 위한 실험음성학적 연구)

  • Kwon, Sung-Mi
    • MALSORI
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    • no.63
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    • pp.47-66
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    • 2007
  • This study aims at exploring the degree of phonetic similarity between Korean and Japanese vowels in terms of acoustic features by performing the speech production test on Korean speakers and Japanese speakers. For this purpose, the speech of 16 Japanese speakers for Japanese speech data, and the speech of 16 Korean speakers for Korean speech data were utilized. The findings in assessing the degree of the similarity of the 7 nearest equivalents of the Korean and Japanese vowels are as follows: First, Korean /i/ and /e/ turned out to display no significant differences in terms of F1 and F2 with their counterparts, Japanese /i/ and /e/, and the distribution of F1 and F2 of Korean /i/ and /e/ in the distributional map completely overlapped with Japanese /i/ and /e/. Accordingly, Korean /i/ and /e/ were believed to be "identical." Second, Korean /a/, /o/, and /i/ displayed a significant difference in either F1 or F2, but showed a great similarity in distribution of F1 and F2 with Japanese /a/, /o/, and /m/ respectively. Korean /a/ /o/, and /i/, therefore, were categorized as very similar to Japanese vowels. Third, Korean /u/, which has the counterpart /m/ in Japanese, showed a significant difference in both F1 and F2, and only half of the distribution overlapped. Thus, Korean /u/ was analyzed as being a moderately similar vowel to Japanese vowels. Fourth, Korean /${\wedge}$/ did not have a close counterpart in Japanese, and was classified as "the least similar vowel."

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Characterization of the Genes of Salmonella typhimurium conferring the penetration of cultured HEp-2 and Chinese hamster cells

  • Park, Jeong-Uk;Jeong, Mi-Yeon;Kim, Mi-Rim;Jeong, Yeong-Gi;Ju, U-Hong
    • 한국생물공학회:학술대회논문집
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    • 2000.04a
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    • pp.584-587
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    • 2000
  • The invasion genes from Salmonella typhimurium were identified by the construction of a cosmid library and subcloning genes into a plasmid vector, pGEM-7Z. The 4.65 kb fragment of the invasion-conferring genomic region of the subclone, pSV6235 was sequenced in both direction. The three open reading frames, which were located at downstream of a promoter region, were designated as sir (Salmonella invasion region)A coding for the 36 amino acids, sirB coding for the 132 amino acids and sirC for the 82 amino acids, respectively. Interesingly, the genomic region of pSV6235 was highly homologous to Yersinia enterocolitica genomic DNA for a high pathogenicity island and Salmonella enteritidis insertion element IS1351 and IS200 DNA. These results show that there could be a significant relationship between S. typhimurium, Y. enterocolitica and S. enteritidis with respect to horizontal evolution process and acquisition of virulence determinants by means of transposon, plasmid or bacteriophage.

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대한산업보건협회 산업보건연구소의 미국 정도관리 참여결과

  • Lee, Seon-Ju;Choe, Ho-Chun;Park, Chan-U;O, Mi-Sun;Lee, Jun-Seung;Jeon, Su-Gyeong;Park, Hwa-Mi;Jeong, Gyu-Cheol
    • 월간산업보건
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    • s.88
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    • pp.57-60
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    • 1995
  • PAT program(The Proficiency Analytical Testing Program)은 미국산업위생협회(American Industrial Hygiene Association AIHA)와 미국산업안전보건연구원(National Institute for Occupational Safety and Health NIOSH)에서 공동주관하는 정도관리로서 일년에 4회 실시하고 있다. 실시항목은 금속(납, 카드뮴, 크롬, 아연), 유리규산, 석면, 유기,용제(Benzen, O-Xylene, Toluene, Carbon Tetrachloride, 1, 1, 1-Trichloroethane, Chloroform, Tetrachloroethylene, 1, 2-Dichloroethane, methanol, p-Dioxane)이다. 대한산업보건협회 산업보건연구소에서는 위의 4가지 항목을 모두 신청하여 1995년 1월에 실시된 120회 부터 참여하였는데 다음은 본 연구소의 120화에 대한 분석방법과 NIOSH로 부터 받은 결과이다.

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Evaluation of Variation Method to Improve the Sensitivity of Immunoradiometric Assay (면역방사계수측정법의 민감도 향상을 위한 변법의 평가)

  • Won-Hyun Kwon;Mi-Ji Kang;;Ji-Sol Park;Jung-In Kim;Kyung-Jae Lee
    • The Korean Journal of Nuclear Medicine Technology
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    • v.27 no.1
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    • pp.29-35
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    • 2023
  • Purpose The concentration of PSA (Prostate Specific Antigen) after radical prostatectomy in prostate cancer patients is a predictor of biochemical recurrence, and the AUA (American Urological Association) is defined as biochemical recurrence when the concentration of PSA is measured at 0.2 ng/mL or more, and when the concentration is measured at 0.2 ng/mL or more at the retest. This standard is also applied our hospital. In this laboratory, the PSA reagent using IRMA (Immunoradiometric Assay) is used, and the sensitivity at a very low value was not as good as the reagent used in the department of laboratory medicine. This study aims to increase the reliability of the results by improving the precision and sensitivity of very low values. Materials and Methods As a reagent for the study, PSA reagent using IRMA was used. As a method to improve the precision and sensitivity of very low values, a variation method on the serum volume(25 uL, 50 uL, 100 uL, 200 uL) was studied, and variation usefulness evaluation was conducted. The evaluation items were compared the results of precision, analytical sensitivity, recovery rate, dilution test, high-dose hook effect test, parallel test and very low concentration values(n = 20). Results The validation results were displayed in the order of 25 uL, 50 uL, 100 uL, 200 uL. As the serum volume increased, it was confirmed that CV (Coefficient of Variation)(%) improved. Analytical sensitivity(ng/mL) was 0.038, 0.041, 0.017, 0.015 and recovery rate(%) was 101±3, 101±3, 99±2, 97±4. very low concentration values(ng/mL) between each volume(n=20) were 0.135±0.068, 0.076±0.050, 0.048±0.034, 0.046±0.034. and high dose hook effect appeared as the serum volume increased. Conclusion Through the variation usefulness evaluation, it was confirmed that as the serum volume increased, the precision and sensitivity improved at very low concentration values. However, it is necessary to pay special attention to the occurrence of high-dose hook effect as the serum volume increases. In the case of tests that requires very low concentration values, it is thought that the reliability of the result will be increased if the variation method is properly used after the variation usefulness evaluation.

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Technological Trends in Space Solar Power (우주태양광발전 기술 동향)

  • Yoon, Yong-Sik;Choe, Nam-Mi;Lee, Ho-Hyung;Choi, Jung-Su
    • Current Industrial and Technological Trends in Aerospace
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    • v.7 no.2
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    • pp.33-39
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    • 2009
  • On 1968 Dr. Peter Glaser introduced the concept of a large solar power satellite system in a high geosynchronous orbit for collection and conversion of solar energy into an electromagnetic microwave beam to transmit usable energy to rectennas on earth. With respect to it, U.S.A, Japan, E.U., etc. noted the Space Solar Power(SSP) as a future new energy resource, performed a substantial research and the concept design, and recently announced detailed plans for realizing SSP projects. While the new technology of SSP is developing, U.S.A. and Japan have a plan to provide the electric service by using SSP 2030. This paper presents the technology trend of advanced countries and the domestic strategies on the SSP development as a green energy and a new energy resource.

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Vortex relaxation for the surface barrier in 3D type-II superconductor (3차원 제2종 초전도체의 표면장벽에 대한 자속의 이완)

  • Kim, Gun-Cheol;Cheon, Mi-Yeon;Kim, Young-Cheol;Kim, Bong-Jun
    • 한국초전도학회:학술대회논문집
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    • v.9
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    • pp.262-265
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    • 1999
  • We report the activation energies which is calculated by adding a term being neglected usually, and magnetic relaxation effects for the surface barrier. The activation energies U at initial magnetization m (m$_{en}$ and m$_{ex}$) and equilibrium magnetization m$_{eq}$ are nearly similar to those of Burlachkov, but the m dependence of the activation energy U is remarkably different. The relaxation effects, which were determined by the m dependence of the activation energies U, are nonlinear for vortex entry, but linear at the initial stage and nonlinear at m(Int) ${\simeq}$ m$_{eq}$ for vortex exit. During relaxation process, the vortex entry at m = m$_{en}$ is faster than the vortex exit at m = m$_{ex}$ by about factor 90. The vortex exit at m = m$_{eq}$ is faster than one at m = m$_{ex}$ by about factor 1.3

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A Study on the Head Type of Korean Women's for Headgear Pattern Making (모자 제작을 위한 여자 머리 형태에 관한 연구 -유형별 머리모형 개발을 중심으로-)

  • Ahn Young-Sill;Suh Mi-A
    • The Research Journal of the Costume Culture
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    • v.12 no.6 s.53
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    • pp.1021-1030
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    • 2004
  • The purpose of this study was to develop and make the head form by setting the region of the head for detailed measurement of the head to make the type of closely fit hat and typifying the head form of Korean women's with each region of the head based on the measurements of each region of the head according characteristics. A total of 285 Korean women's in the age group of 18 to 35 years old. It were measured through the direct measurement method by selecting 67 measurement items. As a result of the findings obtained from cluster analysis could be classified into 3 type. Type 1($46\%$) is U-shaped form, that is high in head height on sides and circumference is smallest, whose facial region and occiput is flattest of three types. Type 2($22.4\%$) is inverted triangle form, that is flat in head ridge, low in head height on sides and wide in the frontal width. Type 3($31.6\%$) is oval form, that is largest in size, has the projected occiput and is of three-dimensional form.

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Effects of a Moderate Drinking Program based on Social Cognitive Theory on College Students with Drinking Problems (문제음주 대학생을 위한 사회인지이론 적용 절주 프로그램의 효과)

  • Kim, Soo Mi;Kim, Hyeon Ok
    • Child Health Nursing Research
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    • v.25 no.2
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    • pp.223-233
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    • 2019
  • Purpose: The purpose of this study was to investigate the effect of the moderate drinking program based on social cognitive theory on changes in the drinking habits of college students with drinking problems. Methods: This study included a total of 68 college students with drinking problems. These participants participated in 10 sessions of a moderate drinking program in which social cognitive theory was applied. Changes in the cognition and behaviors of the participants were then investigated. Results: The moderate drinking program based on social cognitive theory for college students with drinking problems was effective in increasing the subjects' drinking-related knowledge (U=191.50, p<.001), enhancing their drinking refusal self-efficacy(t=8.02, p<.001), and changing their drinking-related attitudes (U=108.50, p<.001), drinking outcome expectancy (t=8.68, p<.001), amount of drinking in a single session ($x^2=25.72$, p<.001), number of drinking sessions per month ($x^2=10.05$, p=.006), and problem drinking behaviors (t=5.77, p<.001). Conclusion: These results can be used to inform a regular on-campus intervention programs for moderate drinking, and to implement education about moderate drinking, thereby increasing the success rate of drinking reduction.

The Effect of Home Care Nursing Intervention in Gynecologic Cancer Patients with Combination Chemotherapy (부인암 환자의 복합항암화학요법 후 가정간호중재 효과)

  • Hwang, Moon-Sook;Song, Hyun-Joo;Chun, Na-Mi;Noh, Gie-Ok
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.14 no.1
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    • pp.31-41
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    • 2007
  • Purpose: This study was designed to evaluate the effect of home care nursing intervention with parenteral hydration and IV anti-emetic therapy on distress, nutritional status, anxiety, depression and QOL in gynecologic cancer patients who were undergoing combination chemotherapy. Methods: Quasi-experimental design was used to test the intervention. Changes of result variables were measured to evaluate effects of the intervention. variables consisted of serum lab results(auto analytic equipment for lab), symptom distress Scale(McCorkle & Young, 1978; Song et al., 2000), nutritional status(body weight, circumference of upper arm, serum protein, serum albumin, oral intake per day), anxiety(Spielberger, 1972; Kim & Shin, 1978), depression(Zung, 1965; Kim, 1995) and QOL(Padilla et al., 1983; Lee & Jo, 1996). Subjects were selected among gynecologic cancer patients(EG 15 patients and CG 15 patients) by convenient sampling. Data collection was done from June to Nov. in 2000. Data were analyzed by Chi-test and Mann-whitney U test using SPSS Win 10.0. Result: Hypothesis 1, the EG receiving this intervention equals to lab test(Hb & ANC, GOT & GPT, BUN & Cr) the CG, was supported(u=69.50 p=.074; u=94.50, p= .455; u= 89.50, p= .339; u=106.50, p= .803; u=75.00, p= .119; u=97.50, p= .523). Hypothesis 2, the EG has less symptom distress than the CG, was also supported(u=43.50, p= .004). Hypothesis 3, the EG has higher nutritional status than the CG, was partially supported on daily oral intake (u=59.00, p= .025). Hypothesis 4, the EG has less anxiety than the CG, was rejected(u=86.50, p= .280). Hypothesis 5, the EG has less depression than the CG, was rejected(u=203.50, p= .228). and the last hypothesis 6, the EG has higher QOL than the CG was supported (u=51.50, p= .011). Conclusion: Home care nursing intervention undergone in this study was found to be effective to reduce patients' symptom distress and to improve their oral intake and QOL.

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