• Title/Summary/Keyword: MI complex

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Dielectric Properties of Complex Cconcentration in IMI-0 Thin Films (IMI-O 초박막의 착체농도에 대한 유전 특성)

  • 정상범;유승엽;박재철;권영수
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1999.05a
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    • pp.345-348
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    • 1999
  • The monolayer behaviors at the air-water interface and the dielectric properties of MI-0 LB films for complex concentration were investigated by the surface pressure-area ($\pi$-A) isotherms and dielectric constant. The molecular area was expanded with increase of metal ions concentration. It is considered that the expansion of molecular area is due to electrostatic repulsion between the polymer chains andhydrophobic increase of ionic strength. In the frequency-dependent complex dielectric constant at room temperature, the real part of dielectric constant($\varepsilon'$) is about 6.0~10.0 in the low-frequency range and is decreasing slowly upto $1O^4$Hz. It decreased abruptly near $1O^5Hz$. It seems to be dielectric dispersion in this frequency range. Also, the imaginary part of dielectric constant ($\varepsilon"$) shows a peak in $1O^5$~$1O^6Hz$. It seems to be dielectric absorption in this frequency range.ange.

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Cu(II) Complexes Conjugated with 9-Aminoacridine Intercalator: Their Binding Modes to DNA and Activities as Chemical Nuclease

  • Kim, Jung-Hee;Youn, Mi-Ryung;Lee, Young-Ae;Kim, Jong-Moon;Kim, Seog-K.
    • Bulletin of the Korean Chemical Society
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    • v.28 no.2
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    • pp.263-270
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    • 2007
  • New mono- and bis-Cu(II)-triazacyclononane(tacn) complex that conjugated with 9-aminoacridine were synthesized, and their binding modes and DNA cleavage activity were investigated in this study. When the classic intercalator, 9-aminoacridine, was conjugated to mono- and bis-Cu(II)-tacn complexes, a significant red-shift and hypochromism in absorption spectrum was apparent in the acridine absorption region upon binding to DNA. Furthermore, the magnitude of the negative reduced linear dichroism signal in the substrate absorption region appeared to be larger than that in the DNA absorption region. These spectral observations indicated that the acridine moiety intercalated when the Cu(II)-tacn complex was conjugated. In contrast, from a close analysis of the circular and linear dichroism spectrum, the aminoacridine-free bis-Cu(II)-tacn complex was concluded to bind at the phosphate groups of DNA. The 9-aminoacridine-free-bis-Cu(II)-tacn complex produces the nicked and linear DNA. On the other hand, 9-aminoacridine conjugated mono-and bis-Cu(II)-tacn complexes showed unspecific binding with negligible DNA cleavage.

A Study on The Universal Design Application of Community Facilities in Housing Complexes (주거단지 커뮤니티 시설에 대한 유니버설 디자인 적용성에 관한 연구)

  • Kim, Na-Yeon;Kim, Jung-Hyun;Lee, Hyo-Chang;Hong, Dong-Jin;Ha, Mi-Kyoung
    • Korean Institute of Interior Design Journal
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    • v.16 no.6
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    • pp.96-105
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    • 2007
  • Residents of apartment complex make various attempts for their community. However, a community space in current apartment complex is planned uniformly without consideration of residents' diversity and the physical aid environment for aged people, children and the handicapped is in limited supply. Community spaces in apartment complexes satisfy various residents but need further study about this. The purpose of this study intends to evaluate the applicability of Universal design of community in apartment complex. Research was done examining 12 different apartment complexes in Seoul, which were all built after the year 2002. Researched community spaces were the senior citizen's center an indoor exercise area and a preschool which were evaluated and measured by passage areas, ramps, stairways and entrances. As a result, the study found that application of Universal design of community spaces in apartment complexes were evaluated relatively low. The environment of community space in apartment complex is not considered the blind, deaf, disabled, children and aged people because the application of these categories doesn't be enforced a law. Hence, Universal design regulations and design guidelines were established to satisfy residents of apartment complex.

A pilot study on differential expression of microRNAs in the ventromedial prefrontal cortex and serum of sows in activity restricted crates or activity free pens

  • Yin, Guoan;Guan, Liwei;Yu, Langchao;Huang, Dapeng
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.9
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    • pp.1469-1474
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    • 2019
  • Objective: Physical activity restriction in sows may lead to behavioral abnormalities and affective disorders. However, the psychophysiological state of these sows is still unclear. As miRNAs can be used as effective markers of psychopathy, the present study aimed to assess the difference in microRNA expression between the long-term activity restricted sows and activity free sows, thus contributing to the understanding of abnormal sow behavior. Methods: Four dry sows (sixth parity, Large${\times}$White genetic line) were selected from activity restricted crates (RC) or activity free pens (FP) separately. microRNAs in the ventromedial prefrontal cortex (vMPFC) and serum were examined using real-time polymerase chain reaction, and the correlation between the miRNAs expressed in the vMPFC and serum was evaluated. Results: miR-134 (1.11 vs 0.84) and miR-1202 (1.09 vs 0.85) levels were higher in the vMPFC of the RC sows than in the FP sows (p<0.01). Furthermore, miR-132 (1.27 vs 1.08) and miR-335 (1.03 vs 0.84) levels were also higher in the RC sows than in FP sows (p<0.05); however, miR-135a, miR-135b, miR-16, and miR-124 levels were not different (p>0.05). The relative expression of serum miR-1202 was higher in the RC sows than in the FP sows (1.04 vs 0.54) (p<0.05), and there was a strong correlation (R = 0.757, p<0.05) between vMPFC and Serum levels of miR-1202. However, no significant difference was observed in miR-16 levels in the serum of the RC sows and FP sows (p>0.05). Conclusion: This pilot study demonstrates that long-term activity restriction in sows likely results in autism or other complex psychopathies with depression-like behaviors. These observations may provide new insights for future studies on abnormal behavior in sows and contribute to research on human psychopathy.

A Study on Dementia Alzheimer's type published to chinese magazine (중의잡지(中醫雜誌)에 보고(報告)된 Alzheimer형(型) 치매에 대(對)한 고찰(考察))

  • Chae, Jong-gul;Lee, Sang-ryong
    • Journal of Haehwa Medicine
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    • v.10 no.1
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    • pp.453-469
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    • 2001
  • This study attempted to analyze the contents of the research papers concerning the diagnosis and treatment of Alzheimer-type dementia presented in the magazine of Chinese Medicine published in China over the period between 1998 and 2000. As a result, the following conclusion was drawn: 1. The Chinese medical category of Alzheimer-type dementia includes amnesia, dementia, stupidity, depression symptom complex, insanity and the like and uses the as the criterion for diagnosis and treatment effect evaluation. 2. The clinical symptoms of Alzheimer-type dementia include lowered intelligence, deterioration of memory, understanding and judgemental power, retardation of the reaction, emotional changes, character changes, behavioral changes and the like and are divided into mild, medium and serious according to the degree of symptom. 3. From the perspective of Bon-Heo-Pyo-Shil(state of deficient vital essence and excessive pestilential vapor), the pattern of Byun-Sung(identification) is divided into deficiency symptom complex, excessive symptom complex and indiscernible fullness and emptiness. The deficiency symptom complex includes deficiency of the liver and kidney, deficiency of essence of the kidney, deficiency of the reservoir of marrow and the like. The excessive symptom complex includes internally blocked stagnant blood, blocking of the passageway due to turbid phlegm, blood stasis due to stagnation of chi, and the like. The indiscernible fullness and emptiness symptom complex includes the deficiency of essence of kidney, blocking of the passageway due to stagnant phlegm, blood stasis due to the deficiency of kidney, blood stasis due to the deficiency of heart and the like. 4. The therapeutics and' prescription of Alzheimer-type dementia include the following: Bo-Shin-Ik-Su-Tang for tonifying the kidney, replenishing the marrow and plugging the essence; Ki-Guk-Ji-Hwang-Hwan-Ga-mi for reinforcing the vital essence of the liver and kidney; Kwi-Bi-Tang-Hap-Yang-Shim-Tang for invigorating the functioning of the spleen and nourishing the heart; Hyel-Bu-Chuk-Eo-Tang-Ga-Mi for activating the blood and resolving the stagnancy of the blood; Bo-Yang-Hwan-Oh-Tang for replenishing chi, activating the blood and resolving the stagnancy of the blood; Beoh-Kwang-Mong-Sung-Tang for invigorating the functioning of the spleen, replenishing the kidney, resolving the phlegm and enlivening the brain; n-Dam-Tang-Ga-Mi for invigorating the functioning of the spleen, replenishing chi, and removing the phlegm and unclogging the passageway); Se-Shim-Tang-Ga-Mi for removing the stagnancy of the liver and resolving the phlegm; and the like. 5. The research papers on, the medication cases of Alzheimer-type dementia understand the pathology of Alzheimer-type dementia from a consistent perspective. They view the pathology of Alzheimer-type dementia as the disease of Bon-Heo-Pyo-Shil(state of deficient vital essence and excessive pestilential vapor) with the combination of the deficiency of essence of the kidney, the deficiency of the brain marrow, blood stasis and blocked phlegm and the like and recommend the prescription of using Bo and Sa simultaneously for treating Alzheimer-type dementia. 6. The research papers on the medication cases of Alzheimer-type dementia reported that the use of creative prescriptions such as Si-Sam-Hang-Ji-Tang, Ji-Yung-Tang, Ka-Mi-Yunh-Ji-Hwan, Ja-Sin-Hwal-Hyel-Tang, Kal-Chang-Ik-Ji-Tang, Ho-Su-Bok-Ji-Tang, Kun-Noe-Ok-Ji-Hap-Je and the like led to the average high efficacy of 85.5%.

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Nucleotide Binding Component of the Respiratory Burst Oxidase of Human Neutrophils

  • Park, Jeen-Woo;Ahn, Soo-Mi
    • BMB Reports
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    • v.28 no.3
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    • pp.275-280
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    • 1995
  • The respiratory burst oxidase of neutrophils is a multicomponent enzyme, domant in resting cells, that catalyzes the reduction of oxygen to $O_{2}^{-}$ at the expense of NADPH. In the resting neutrophil, some of the components of the oxidase, including proteins p47 and p67, are in the cytosol, while the rest are in the plasma membrane. Recent evidence has suggested that at least some of the cytosolic oxidase components exist as a complex. The cytosolic complex with a molecular weight of ~240 kDa was found to bind to blue-agarose and 2',5'-ADP-agarose, which recognize nucleotide requiring enzymes. In order to identify the nucleotide binding component of the cytosolic complex we purified recombinant p47 and p67 fusion proteins using the pGEX system. Pure recombinant p47 was retained completely on 2',5'-ADP-agarose, whereas pure recombinant p67 did not bind to these affinity beads. On the basis of these results, we infer that p47 may contain the nucleotide binding site.

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A Study on the Development of Forest Healing Village Based on the Survey on the Stakeholder Perception (산촌 이해관계자 의견 수렴을 통한 산림치유마을 조성방안 연구)

  • Jeong, Mi-Ae;Seo, Jeong-Weon
    • Journal of Korean Society of Rural Planning
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    • v.22 no.3
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    • pp.11-19
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    • 2016
  • The purpose of this study was to develop the strategy on activation of village by forest healing. Researcher conducted the questionnaire survey for forest healing village development to classify the mountain's characteristics by the three factors(linkage resource, program, facilities). In result, village characteristics were divided into two types: single element outstanding type(resource), complex element outstanding type(resource+program, resource+facilities). The development of forest healing village have to focused on the forest healing service recipient and mountain village characteristics. In conclusion, relationship between forest healing recipient and mountain characteristics was as follows: single type (resource) - public; complex type (resource+program) - chronic disease, social vulnerable people; complex type (resource+facilities) - severe disease. The detailed guideline for forest healing village needs to be established according to the mountain characteristics.

Reduction in mechanical allodynia in complex regional pain syndrome patients with ultrasound-guided pulsed radiofrequency treatment of the superficial peroneal nerve

  • Chae, Won Soek;Kim, Sang Hyun;Cho, Sung Hwan;Lee, Joon Ho;Lee, Mi Sun
    • The Korean Journal of Pain
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    • v.29 no.4
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    • pp.266-269
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    • 2016
  • The superficial peroneal nerve is vulnerable to damage from ankle sprain injuries and fractures as well as surgery to this region. And it is also one of the most commonly involved nerves in complex regional pain syndrome type II in the foot and ankle region. We report two cases of ultrasound-guided pulsed radiofrequency treatment of superficial peroneal nerve for reduction of allodynia in CRPS patients.

A Study on Dining and Kitchen Space in Unit of Complex Buildings Regarding the Change of Life Style (현대 라이프스타일의 변화에 따른 주상복합건물 주호에서의 식생활 공간에 관한 연구)

  • Kim, Ji-Woo;Yoo, Sung-Eun;Ha, Mi-Kyoung
    • Proceeding of Spring/Autumn Annual Conference of KHA
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    • 2004.11a
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    • pp.55-60
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    • 2004
  • Regarding the change of life-style, dining and kitchen space has been considered to be more important than before in many ways. At this point of time, it is very significant to understand the trend of the recently planned dining and kitchen space. Thus the purpose of this study is to analyze the dining and kitchen space in the unit of the complex buildings. It is believed that the accumulated data will be the basic information to develop more efficient and convenient dining and kitchen space in future.

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Forthcoming Big Data in Smart Cities: Experiment for Machine Learning Based Happiness Estimation in Seoul City (빅데이터를 이용한 서울시 행복지수 분석 및 예측을 위한 실험 및 고찰)

  • Shin, Dongyoun;Song, Yu-Mi
    • Journal of KIBIM
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    • v.7 no.1
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    • pp.28-35
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    • 2017
  • Cities have complex system composed diverse activities. The activities in cities have complex relationship that creates diverse urban phenomena. Big Data is emerging technology in order to understand such complex network. This research aims to understand such relations by analysing the diverse city indexes. 28 indexes were collected in 25 of districts in Seoul city and analysed to find a weighted correlation. By defining the correlation values of certain years, it tries to predict the missed index values, "happiness" of each districts in other years. The result presents that the overall prediction accuracy 70.25%. However, for further discussion, the result is considered that this methods may not enough to use in practice, since the data has inconstant accuracy by different learning years.