• Title/Summary/Keyword: MGF

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모색발현 유전자의 DNA Marker를 이용한 쇠고기 품종 판별

  • Sin, Seong-Cheol;Chae, Ji-Seon;Kim, Hye-Jeong;Choe, Eun-Ju;Kim, Hui-Seon;Kim, Hyeon-Seok;Jeong, Ui-Ryong;Jeong, Gu-Yong
    • Proceedings of the Korean Society for Food Science of Animal Resources Conference
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    • 2004.05a
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    • pp.172-176
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    • 2004
  • 본 연구는 축우의 모색발현을 조절하는 MCIR, MGF 및 TYRP1 3종류의 모색 유전자를 이용하여 한우육 판별기술을 개발하고자 PCR-RFLP 기법으로 이들 모색유전자 좌위의 대립유전자를 검출하고 각 품종 간 RFLP 유전자형 출현빈도를 비교 분석하였다. MCIR 유전자의 RFLP 유전자형 출현빈도에서 한우는 e/e과 E+/e형이 출현되었고 이외의 다른 유전자형의 출현은 전혀 인정되지 않았다. 그러나, Holstein종 젖소는 $E^D/E^D$$E^D/e$ 2종류의 유전자형 그리고 Angus종에서는 $E^D/E^D$, $E^D/E^++$$E^D/e$ 3종류의 유전자형이 각각 출현하여 한우와 이들 두 품종간의 MCIR유전자형 출현빈도에 뚜렷한 차이가 인정되었다. MGF 유전자의 RFLP 유전자형 출현빈도에서 한우는 R/r과 r/r형이 각각 25%와 75%로 rr형의 출현율이 비교적 높았으며 Holstein종과 Angus 종은 R/r형이 100% 출현했으며, Charolais 종은 rr형이 100% 출현하였고 이외의 다른 유전자형은 인정되지 않았으며 Hereford종은 RR형이 80% 그리고 R/r형이 20%의 출현율을 보여 RR형의 출현율이 매우 높아 한우와 Holstein 및 육우 품종간의 MGF 유전자형 출현빈도에 명백한 차이가 인정되었다. 따라서, 소 모색관련 MCIR과 MGF 유전자의 품종 특이적 PCR-RFLP 유전자형은 한우육과 국내산 Hostein 젖소육 및 도입육우 품종을 식별하는데 매우 유용한 DNA marker로 이용될 수 있음이 확인되었다.

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A Study on The Marine Geographical Framework Data in Korea (해양기본지리정보 구축에 관한 기초연구)

  • 최윤수;오순복;박병문;김정현;서상현
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.20 no.3
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    • pp.293-301
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    • 2002
  • MGF(Marine Geographical Framework) data are the essential data sets concerning graphical and attribute information on coast and ocean among various marine-related data, which consist of framework data of the National Spatial Data Infrastructure(NSDI). This study did research and analyzed the development of current data, the situation of its usage, related technical environment and case study of foreign countries through the survey on the users and experts. Then the item of marine geographical framework data was selected in accordance with the measures for usage and management of possible MGF data. A map was pilot producted based on selected items and MGF data was presented through making up some problems shown ill the process. The importance of GIS will be growing continuously which can develop, deal with and provide the various data to efficiently manage coast and ocean. Accordingly, the MGF data will be applied to various areas such as Internet or raw data for marine information system.

Numerical Analysis and Simulation for the Pricing of Bond on Term-Structure Interest Rate model with Jump (점프 항을 포함하는 이자율 기간구조 모형의 채권 가격결정을 위한 수치적 분석 및 시뮬레이션)

  • Kisoeb Park
    • Journal of Internet Computing and Services
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    • v.25 no.2
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    • pp.93-99
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    • 2024
  • In this paper, we derive the Partial Differential Bond Price Equation (PDBPE) by using Ito's Lemma to determine the pricing of bond on term-structure of interest rate (TSIR) model with jump. From PDBPE, the Maclaurin series (MS) and the moment-generating function (MGF) for the exponential function are used to obtain a numerical solution (NS) of the bond prices. And an algorithm for determining bond prices using Monte Carlo Simulation (MCS) techniques is proposed, and the pricing of bond is determined through the simulation process. Comparing the results of the implementation of the above two pricing methods, the relative error (RE) is obtained, which means the ratio of NS and MCS. From the results, we can confirm that the RE is less than around 2.2%, which means that the pricing of bond can be predicted very accurately using the proposed algorithms as well as numerical analysis. Moreover, it was confirmed that the bond price obtained using the MS has a relatively smaller error than the pricing of bond obtained by using the MGF.

Effects of Castration on Androgen Receptor, IGF-I Ea, MGF and Myostatin Gene Expression in Skeletal Muscles of Male Pigs

  • Yao, Yuchang;Cai, Zhaowei;Zhang, Lifan;Zhao, Chunjiang;Wu, Keliang;Xu, Ningying;Liu, Gang;Wu, Changxin
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.8
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    • pp.1069-1077
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    • 2009
  • Castration of male pig produces significant negative effects on skeletal muscle development. The androgen receptor (AR), two splice variants of insulin-like growth factor-I (IGF-I Ea and MGF) and the myostatin gene may play important roles in this process. In the present study, the expression of AR, IGF-I Ea, MGF and myostatin genes in three skeletal muscles, the brachialis, longissimus and semitendinosus, were studied using real-time quantitative RT-PCR. Our experimental design used 14 pairs of male Landrace sire${\times}$Yorkshire dam piglets. The two piglets in each pair were full sibs, one of which was castrated at 21 d of age; the other remained intact. The study group was divided into subgroups of equal size. Animals in the first subgroup were slaughtered at 147 d and those of the second at 210 d of age. Carcass weight and lean meat yield were similar between boars and barrows at 147 d of age (p>0.05), whereas barrows had lower carcass weight and less lean meat yield at 210 d of age (p<0.05). Castration caused down-regulation of AR gene expression at both 147 and 210 d of age (p<0.05). The two splice variants of the IGF-I gene from porcine skeletal muscle were cloned using RT-PCR, and it was found that MGF differs from IGF-I Ea in having a 52-base insert in the last coding exon of the mRNA. Both splice variants were down-regulated by castration only at 210 d of age (p<0.05). No differences in expression of the myostatin gene were observed between boars and barrows at either 147 or 210 d of age (p>0.05). These results suggest that the downregulation of AR, IGF-I Ea and MGF gene expression following castration helps to explain the negative effect of castration on skeletal muscle development.

The Suppressive Effects of Integrin Antibodies on the Infection of Hantaan Virus in Fibroblasts (한탄바이러스의 섬유아세포 감염에 대한 Integrin 항체의 억제 효과)

  • Park, Ho-Sun;Kim, Ki-Duk;Kim, Sung-Kwang
    • Journal of Yeungnam Medical Science
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    • v.15 no.1
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    • pp.55-66
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    • 1998
  • Pathophysiological mechanism of hemorrhagic fever with renal syndrome (HFRS) is not fully understood. Major clinical findings of HFRS patients are widespread hemorrhage, acute renal failure and shock. Basic lesion is vascular injury with microvascular hemorrhage and relatively little inflammation. According to autopsy findings, renal medulla shows focal hemorrhage, tubular necrosis and interstitial mononuclear infiltrates. The predominant cell type in the renal and pulmonary interstitium is a fibroblast and it participates in the healing process at the injury site by secreting a large amount of extracellular matrix proteins. Cultured human lung fibroblasts and Mongolian gerbil fibroblasts were known to be good host cells for the hantaan virus. It is possible that not only the endothelial cell but also the fibroblast is a target of Hantaan virus and the fibroblast might be involved in the pathogenesis and the healing process in HFRS. Integrins are adhesion molecules, and act as receptors for many extracellular matrix proteins. Recently, there are many reports that cell surface integrins influence on some viral infections or reversely viruses influence on the expression of integrins. The ${\alpha}_5{\beta}_1$ integrin is a major receptor for the fibronectin which is an important extracellular matrix protein secreted by fibroblasts. In this study, the role of ${\alpha}_5{\beta}_1$ integrin in the infection of Hantaan virus was examined by using anti-${\alpha}_5{\beta}_1$, integrin, anti-${\alpha}_5$ integrin and anti-${\beta}_1$, integrin antibodies in chicken embryo fibroblasts (CEF) and Mongolian gerbil fibroblasts(MGF). The treatment of anti-${\alpha}_5{\beta}_1$, integrin antibody in CEF reduced the virion titers 26.8% and the amount of nucleocapsid N protein 32.6% when compared with control CEF. When MGF were treated with anti-${\alpha}_5$, anti-${\beta}_1$ and anti-${\alpha}_5{\beta}_1$ integrin antibodies, virion titers were reduced by 26.5%, 29.4% and 28.7% and the amount of nucleocapsid N protein were reduced by 65.2%, 59.7% and 72.6%. These results suggested that ${\alpha}_5{\beta}_1$ integrin might act as a receptor for the Hantaan virus or blocking of ${\alpha}_5{\beta}_1$ integrin influences on the viral replication in CEF and MGF. It is also possible that the blocking of only one subunit of integrin represents similar results in that of whole molecule.

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Performance Evaluation of FMS Using Generalized Stochastic Petri Nets (Generalized Stochastic 페트리네트를 이용한 유연생산시스템의 성능평가)

  • 서경원;박용수;박홍성;김종원
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1994.10a
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    • pp.653-657
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    • 1994
  • A symbolic performance analysis approach for flexible for manufactring systems (FMS) can be formulated based on the integration of Petri Nets (PN) and moment generating function (MGF) concept. In this method, generalized stochastic Petri Nets are used to define performance models for FMS, then MGF nased approach for evaluating stochastic PN is used to derive performance parameters of PN, and finally system performance is calculated. A GSPN model of machine cell is shown to illustrate the proposed method for evaluating such performance indices as production rate, utilization, work-in-process and lead time. The major advantage of this method over existing performance evaluation of FMS is the ability to compute symbolic solutions for performance. Finally future research toward automating performance measure for GSPN models of FMS is discussed.

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Electrical and transport properties of carbon chains encapsulated within CNT

  • KIM, Tae Hyung;KIM, Hu Sung;KIM, Yong-Hoon
    • Proceeding of EDISON Challenge
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    • 2017.03a
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    • pp.457-462
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    • 2017
  • A linear carbon chain with pure sp hybridization has been intensively studied for the application of its intrinsic electrical properties to electronic devices. Owing to the high chemical reactivity derived from its unsaturated bond, encapsulation by carbon nanotubes (CNT) is provided as a promising method to stabilize the geometry of the linear carbon chain. Although the influence of CNT on the carbon chain has extensively been studied in terms of both electronic structure and geometries, the electron transport properties has not been discussed yet. In this regard, we provide the systematic atomic-scale analyses of the properties of the linear carbon chain within CNT based on a computational approach combining density-functional theory (DFT) and matrix green function (MGF) method. Based on the DFT calculations, the influence of CNT on electronic structures of the linear carbon chain is provided as well as its electrical origin. Via MGF calculations, we also identify the electron transport properties of the carbon chain - CNT complex.

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Reinforcement of Polychloroprene by means of Silia and Glass Fiber (Silica와 Glass Fiber에 의한 Polychloroprene의 보강(補强))

  • Yoo, Chong-Sun;Paik, Nam-Chul
    • Elastomers and Composites
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    • v.23 no.3
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    • pp.223-229
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    • 1988
  • The effect of triazine thiol derivative on the physical properties of silica-polychloroprene(CR) composites and glass fiber(MGF)-CR composites was investigated. Optimum cure time of the MGF composites filled with 2-dibuthylamino-4, 6-dithiol-s-triazine(DBT) was the fastest one, while maximum torque was the best in case of the silica composites filled with s-triazine-2,4,6-trithiol(TAT) on the Oscillating Disk Rheometer(ODR) test. Stress-strain curves of the composites showed that the physical properties such as 100% modulus, 300% modulus, tensile strength of the silica composites filled with DBT was very satisfactory and the silica composites filled with TAT was higher density of crosslinking than other crosslinked elastomer. In aging properties, elastomer filled DBT and TAT were progress post-curing reaction with increasing of aging time and it have been improved the tensile strength and crosslinking density.

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Effect of Microdiversity and Macrodiversity on Average Bit Error Probability in Gamma-Shadowed Rician Fading Channels

  • Milenkovic, Vladeta Vasilije;Sekulovic, Nikola Milos;Stefanovic, Mihajlo Caslav;Petrovic, Mile Branko
    • ETRI Journal
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    • v.32 no.3
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    • pp.464-467
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    • 2010
  • In this letter, we analyze the error performance of a mobile communication system with microdiversity and macrodiversity reception in gamma-shadowed Rician fading channels for a binary differential phase-shift keying modulation scheme. Analytical expressions for the probability density function (PDF) and moment-generating function (MGF) are derived. The average bit error probability can be calculated by averaging the conditional bit error probability over the PDF or using the MGF-based approach. Numerical results are graphically presented to show the effects of macrodiversity, correlation, number of diversity branches, and severity of both fading and shadowing.

Performance Analysis with Imperfect Channel Estimation in Cooperative Diversity (공조 다이버시티에서의 부정확한 채널 추정을 고려한 성능 분석에 관한 연구)

  • Ro Sang-Min;Hong Dae-Sik
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.7A
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    • pp.689-695
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    • 2006
  • This paper focuses on the accurate performance evaluation of cooperative diversity technique with imperfect channel estimates. The channel environment for simulations and performance evaluation is supposed to be the slowly time-varying Rayleigh fading channel. The framework of the performance evaluation is based on the Moment Generating Function(MGF) approach. To apply the effect of this channel estimation error into the performance evaluation, we import an useful Gaussian approximation in formulating the effective noise component and the additive noise. The average BER performance of cooperative diversity with M-PSK and M-QAM is computed as a function of the ratio of the signal to the effective noise based on the approximation. The verification of computed performance is provided with simulations. The evaluated performance matches up to simulation results even in a low SNR region.