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Microwave Cavity with Controllable Temperature for In Vitro Hyperthermia Investigations

  • Kiourti, Asimina;Sun, Mingrui;He, Xiaoming;Volakis, John L.
    • Journal of electromagnetic engineering and science
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    • v.14 no.3
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    • pp.267-272
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    • 2014
  • Hyperthermia is a form of cancer treatment in which affected human tissue is exposed to $>40^{\circ}C$ temperature. In this paper, our goal is to assess the efficacy of fullerene agents to reduce heating time for cancer treatment. Such agents can accelerate heating of cancer cells and improve hyperthermia treatment efficacy. Typically, in vitro testing involves cancer cell culturing, heating cell cultures in accordance to specifications, and recording cancer cell viability after hyperthermia. To heat cell cultures, we design and evaluate a 2.4-GHz microwave cavity with controllable temperature. The cavity is comprised of a polystyrene cell culture dish (diameter = 54 mm, height = 13.5 mm) and a printed monopole antenna placed within the cavity for microwave heating. The culture temperature can be controlled through the intensity and duration of the antenna's microwave radiation. Heating experiments were carried out to validate the cavity's performance for F-12K culture medium (Kaighn's F-12K medium, ATCC). Importantly, fullerene agents were shown to reduce heating time and improve hyperthermia treatment efficacy. The culture medium temperature increased, on average, from $24.0^{\circ}C$ to $50.9^{\circ}C$ (without fullerene) and from $24.0^{\circ}C$ to $56.8^{\circ}C$ (with 3 mg/mL fullerene) within 15 minutes.

Removal of Rhodamine B Dye Using a Water Plasma Process (수중 플라즈마 공정을 이용한 Rhodamine B 염료의 제거)

  • Kim, Dong-Seog;Park, Young-Seek
    • Journal of Environmental Health Sciences
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    • v.37 no.3
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    • pp.218-225
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    • 2011
  • Objectives: In this paper, a dielectric barrier discharge (DBD) plasma reactor was investigated for degrading the dye Rhodamine B (RhB) in aqueous solutions. Methods: The DBD plasma reactor system in this study consisted of a plasma component [titanium discharge (inner), ground (outer) electrode and quartz dielectric tube], power source, and gas supply. The effects of various parameters such as first voltage (input power), gas flow rate, second voltage (output power), conductivity and pH were investigated. Results: Experimental results showed that a 99% aqueous solution of 20 mg/l Rhodamine B is decolorized following an eleven minute plasma treatment. When comparing the performance of electrolysis and plasma treatment, the RhB degradation of the plasma process was higher that of the electrolysis. The optimum first voltage and air flow rate were 160 V (voltage of trans is 15 kV) and 3 l/min, respectively. With increased second voltage (4 kV to 15 kV), RhB degradation was increased. The higher the pH and the lower conductivity, the more Rhodamine B degradation was observed. Conclusions: OH radical generation of dielectric plasma process was identified by degradation of N, N-dimethyl-4-nitrosoaniline (RNO, indicator of OH radical generation). It was observed that the effect of UV light, which was generated as streamer discharge, on Rhodamine B degradation was not high. Rhodamine B removal was influenced by real second voltage regardless of initial first and second voltage. The effects of pH and conductivity were not high on the Rhodamine B degradation.

Fracture Toughness and Slinding Wear Properties of ABOw/AC4CH by Binder Additives (ABOw/AC4CH의 바인더 종류에 따른 파괴인성 및 미끄럼마모 특성)

  • Park, Won-Jo;Jung, Jae-Wook;Choi, Yong-Bum;Lee, Kwung-Young
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2002.10a
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    • pp.373-378
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    • 2002
  • Metal matrix composites have a great interest in recent years because high specific strength, high specific stiffness characteristics, and application ranges of the composites are extend to variety industry. In this paper, an investigation was performed on the plane strain fracture toughness and slinding wear properties of AC4CH alloy(Al-Si-Mg line) reinforced with 20wt% aluminum borate whisker expect one, which contained a inorganic binder($TiO_2$). the binder led to the formation of strengthen the whisker each other. The test of fracture toughness was using CT(half size) specimen of thickness 12.5mm, width 25mm. and test of slinding wear of using tribo a pin-on-disk machine and lubricant is used without paraffine 8.2CST at room temperature. As results, Fracture toughness $K_{IC}$ is $8.7MPa-m^{05}$ for ABOw/AC4CH, $9.28MPa-m^{05}$ for ABOw/AC4CH added $TiO_2$. but AC4CH alloy was violated the critical stipulated by ASTM standard for valid measurement of $K_{IC}$. In case of, it was performed $J_{IC}$ test instead of $K_{IC}$ based on ASTM E 1820.

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An Implementation of IPMG for Multimedia Service with the Convergence of Broadcasting and Communications (통신방송의 융합형 멀티미디어 서비스를 지원하는 IPMG(IP Media Gateway) 구현)

  • Cho, Kwang-Hyun;Kim, Hyun-Cheol;Cho, Yok-Yon;Park, Deuk-In;Won, Heon;Ahn, Kwang-Yong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.2B
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    • pp.59-68
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    • 2008
  • In order to activate the digital broadcasting in Korea, the analog broadcasting will have been closed down until 2012. Recently IPTV(Internet Protocol TV) thorough internet has been regarded as the fourth media following the terrestrial, satellite, and cable for the digital broad casting. And it has been the important medium for the communication and broadcasting system. However IP is not easy to replace the entire broadcasting system with the digital - type broadcasting system. For the digital broadcasting, we should replace all TV sets, install the settop-boxes to receive the various IP media, solve problems about time delaying when changing channels, and support communication and broadcasting consolidation service for such as PVR and Network CCTV. IPMG is the digital converter that is able to solve these problems. In this paper, I'll develop and analyze IPMG converter's performance which sends and receives both the analogue and digital broadcasting signals through various media gives the Network PVR service.

Fabrication & Characteristics of SIR Microsrip Bandpass Filters using Deposition of High-Tc Superconducting Epitaxial Films (고온 초전도 에피텍셜 박막을 이용한 SIR 마이크로스트립 대역통과 필터의 제작 및 특성연구)

  • Park, Kyung-Kuk;Chung, Dong-Chul;Jeong, Yong-Chae;Lim, Sung-Hun;Yim, Seong-Woo;Han, Byoung-Sung
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.48 no.5
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    • pp.326-332
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    • 1999
  • In this paper, we designed and fabricated High-Tc Superconducting (HTS) microstrip bandpass filters using Stepped Impedance Resonators(SIR) and studied on their characteristics. The $high-T_c$ superconducting $Y_1Ba_2Cu_3O_{7-x}$ epitaxial films were deposited by Pulse Laser Deposition (PLD) system on MgO. The fabricated filters were designed so as to operate in Ku band with central frequency 17.25 GHz, bandwidth 2.896% and ripple 0.01 dB. These filters were composed of parallel coupled microstrip SIR of which impedance ratio (K) are 0.5, 1.5. In the measured response, HTS filters had showed insertion loss below -0.5 dB. For comparison with normal conducting filter, we fabricated the Au counterpart that consists of the resonators as K=1.5 in the same dimension and measured performance of the Au filter. In comparison, HTS filter designed optimally got superior response to gold conterpart.

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Temperature dependence of optical energy gaps and thermodynamic function of $Zn_{4}SnSe_{6}$ and $Zn_{4}SnSe_{6}:Co^{2+}$ single crystals ($Zn_{4}SnSe_{6}$$Zn_{4}SnSe_{6}:Co^{2+}$ 단결정에서 광학적 에너지 띠 및 열역학적 함수의 온도의존성 연구)

  • Kim, D.T.;Kim, N.O.;Choi, Y.I.;Kim, B.C.;Kim, H.G.;Hyun, S.C.;Kim, B.I.;Song, C.I.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.08a
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    • pp.25-30
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    • 2002
  • The ternary semiconducting compounds of the $A_{4}BX_{6}$(A=Cd, Zn, Hg; B=Si, Sn, Ge; X=S, Se, Te) type exhibit strong fluorescence and high photosensitivity in the visible and near infrared ranges, so these are supposed to be materials applicable to photoelectrical devices. These materials were synthesized and single crystals were first grown by Nitsche, who identified the crystal structure of the single crystals. In this paper. author describe the undoped and $Co^{2+}$-doped $Zn_{4}SnSe_{6}$ single crystals were grown by the chemical transport reaction(CTR) method using iodine of $6mg/cm^{3}$ as a transport agent. For the crystal. growth, the temperature gradient of the CTR furnace was kep at $700^{\circ}C$ for the source aone and at $820^{\circ}C$ for the growth zone for 7-days. It was found from the analysis of x-ray diffraction that undoped and $Co^{2+}$-doped $Zn_{4}SnSe_{6}$ compounds have a monoclinic structure. The optical absorption spectra obtained near the fundamental absorption edge showed that these compounds have a direct energy gaps. These temperature dependence of the optical energy gap were closely investigated over the temperature range 10[K]~300[K]

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Effects of Heat Pre-Treatment and Reactor Configurations on the Anaerobic Treatment of Volatile Solids (열전처리와 반응조 형태가 고형 유기물의 혐기성 처리에 미치는 영향)

  • Hong, Young-Soek;Bae, Jae-Ho
    • Journal of Korean Society of Water and Wastewater
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    • v.10 no.2
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    • pp.104-116
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    • 1996
  • Anaerobic digestion is generally used for the treatment of volatile organic solids such as manure and sludge from waste water treatment plants. However, the reaction rate of anaerobic process is slow, and thus it requires a large reactor volume. To minimize such a disadvantage, physical and chemical pre-treatment is generally considered. Another method to reduce the reactor size is to adopt different reactor system other than CSTR. In this paper, the effects of heat pre-treatment and reactor configurations on the anaerobic treatability of volatile solids was studied. Carrot, kale, primary sludge, and waste activated sludge was chosen as the test materials, and the BMP method was used to evaluate the maximum methane production and first order rate constants from each sample. After the heat treatment at $130^{\circ}C$ for 30min., the measured increase in SCOD per gram VS was up to 394 mg/L for the waste activated sludge. However, the methane production potential per gram VS was increased for only primary and waste activated sludge by 17-23%, remaining the same for carrot and kale. The overall methane production process for the tested solids can be described by first order reactions. The increased in reaction constant after heat pre-treatment was also more significant for the primary and waste activated sludge than that for carrot and kale. therefore, the heat pre-treatment appeared to be effective for the solids with high protein contents rather than for the solids with high carbohydrate contents. Among the four reactor systems studied, CSTR, PFR, CSTR followed by PFR, and PFR with recycle, CSTR followed by PFR appeared to be the best choice considering methane conversion rate and the operational stability.

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Agricultural Methods for Toxicity Alleviation in Metal Contaminated Soils: A Review

  • Arunakumara, Kkiu;Walpola, Buddhi Charana;Yoon, Min-Ho
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.2
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    • pp.73-80
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    • 2013
  • Due to the fact that possible risk associated with soil-crop-food chain transfer, metal contamination in croplands has become a major topic of wide concern. Accumulation of toxic metals in edible parts of crops grown in contaminated soils has been reported from number of crops including rice, soybean, wheat, maize, and vegetables. Therefore, in order to ensure food safety, measures are needed to be taken in mitigating metal pollution and subsequent uptake by crop plants. Present paper critically reviewed some of the cost effective remediation techniques used in minimizing metal uptake by crops grown in contaminated soils. Liming with different materials such as limestone ($CaCO_3$), burnt lime (CaO), slaked lime [$Ca(OH)_2$], dolomite [$CaMg(CO_3)_2$], and slag ($CaSiO_3$) has been widely used because they could elevate soil pH rendering metals less-bioavailable for plant uptake. Zn fertilization, use of organic amendments, crop rotation and water management are among the other techniques successfully employed in reducing metal uptake by crop plants. However, irrespectively the mitigating measure used, heterogeneous accumulation of metals in different crop species is often reported. The inconsistency might be attributed to the genetic makeup of the crops for selective uptake, their morphological characteristics, position of edible parts on the plants in respect of their distance from roots, crop management practices, the season and to the soil characteristics. However, a sound conclusion in this regard can only be made when more scientific evidence is available on case-specific researches, in particular from long-term field trials which included risks and benefits analysis also for various remediation practices.

Studies on the Production of Amino Acids by Methanol-Utilizing Bacteria (Methanol 자화세균에 의한 아미노산의 생성에 관한 연구)

  • 주동기
    • Korean Journal of Microbiology
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    • v.14 no.1
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    • pp.8-16
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    • 1976
  • About 600 strains of bacteria which can utilize methanol as the sole source of carbon were isolated from natrual sources, and their ability to produce amino acids on the medium containing methanol as the sole source of carbon was tested by paper chromatography, by which 3 strains were screened by virtue of their relatively shperior amino acid production. These were tentatively identified as follows ; one strain belonged to the genus methylomonas, while the remaining two were members of the genus Hyphomicrobium. Further studies on their growth characteristics were carried out with relation to amino acid production. According to these experiments, the following results were obtained. 1) No vitamin added was effective for the growth enhancement. 2) Optimum initial concnetration of methanol was proved to be one per cent (v/v), and no conspicuous effect of feeding methanol on the growth of these bacteria ould be observed, provide that the initial methanol concentration was controlled to 1 per cent. 3) Among the nitrogen sources tested, 0.1 per cent of ${(NH_4)}_2SO_4$ enabled the best growth. 4) Addition of 0.001 per cent $MgSO_4.$ $7H_2O$ largely increased the growth of all three strains. Other metal ions tested were either not effective or strongly inhibitory for the growth. 5) Addition of 0.1 per cent each of yeast extract, corn steep liquor, beef extract, and peptone also increased the growth markedly. 6) About $75{\mu}$g/ml of alanine could be obtained finally after 64 hr culture of Hypm. A on the medium lcontaining 0.1 per cent yeast extract and 1 percent methanol. Approximately $40.{\mu}$g/ml of glutamic acid by Hypm. GA and $43.{\mu}$g/ml of alanine by Mtlm. A were produced at the same culture conditions.

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Effect of Whole Body Vibration on Osteoporotic Trabecular Bone of Rats - Compared with the Effect of Actonel (전신진동이 골다공증이 유발된 쥐 해면골에 미치는 영향 - 골다공증 치료제 효과와 비교)

  • Ko, Chang-Yong;Lee, Tae-Woo;Woo, Dae-Gon;Kim, Hyo-Seon;Kim, Han-Sung;Lee, Beob-Yi;Lim, Do-Hyung
    • Journal of the Korean Society for Precision Engineering
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    • v.25 no.5
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    • pp.148-154
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    • 2008
  • Pharmacotherapy was mainly used to treat osteoporosis. However, some researches showed that pharmacotherapy could induce unexpected adverse effects. Some studies showed that whole body vibration affected beneficially osteoporosis. This paper studied the effect of whole body vibration fur osteoporosis compared with the effect of pharmacotherapy. 10 female rats were used and allocated into 4 group, CON, SHAM, DRUG, and WBV. Rats except SHAM group were ovariectomised to induce osteoporosis. Rats in WBV group were stimulated in whole body vibration at magnitude of $1mm_{peak-peak}$ and frequency 45Hz, for 8 weeks (30 min/day, 5 days/week). Rat in DRGU group was orally administered the Actonel (0.58mg/Kg), for 8 weeks (5days/week). The $4^{th}$ lumbar in rats were scanned at a resolution of $35{\mu}m$ at baseline, before stimulation, and 8 weeks after stimulation by In-vivo micro computed tomography. For detecting and tracking changes of biomechanical characteristics (morphological and mechanical characteristics) in lumbar trabecuar bone of rats, structural parameters were measured and calculated from acquiring images and finite element analysis was performed. In the results, loss of quantity and change of structure of trabecular bone in WBV group were smaller than those in both CON and SHAM groups. In addition, mechanical strength in WBV group was stronger than that in both CON and SHAM groups. In contrast, biomechanical characteristics in WBV group were similar with those in DRUG group. These results showed that reasonable whole body vibration was likely to treat osteoporosis and be substituted partly for drug treatment.