• Journal of Music and Human Behavior
• /
• v.21 no.1
• /
• pp.49-68
• /
• 2024

This study aims to acoustically analyze Korean language characteristics and convert these findings into musical elements, providing foundational data for evidence-based music-language rehabilitation. We collected voice data from thirty men and thirty women aged 19-25, each providing six-syllable prosodic units composed of two accentual phrases, including both declarative and interrogative sentences. Analyzing this data with Praat, we extracted syllabic acoustic properties and conducted statistical analyses based on acoustic properties, sentence type, gender, and particle presence. Significant differences were found in syllable frequency and duration based on accentual phrases and prosodic units (p < .001), with interrogative showing higher frequencies and declaratives longer durations (p < .001). Female frequencies were significantly higher than males' (p < .001), with longer durations observed (p < .001). Particle syllables also showed significantly stronger intensities (p < .001). Finally, we presented melodies converted from these acoustic properties into musical scores based on pitch, duration, and accent. The insights from this analysis of six-syllable Korean sentences will guide further research on developing a system for melodizing large-scale Korean speech data, expected to be crucial in music-based language rehabilitation.

• Journal of the Korean Society of Radiology
• /
• v.18 no.2
• /
• pp.109-117
• /
• 2024

In order to determine the level of awareness of nuclear power generation and Fukushima contaminated water, this study conducted an online survey targeting the general public living in the Busan area and analyzed a total of 201 questionnaires. Independent samples t-test and one-way analysis of variance were conducted to verify differences in variables according to the characteristics of the study subjects, and correlation analysis was conducted to confirm the correlation between variables. First, the results of the study showed that women had a more negative perception of nuclear power generation and Fukushima contaminated water than men. In terms of age, it was found that people in their 40s and older had a high level of negative perception. In terms of political inclination, progressive respondents showed a higher negative perception toward nuclear power generation and Fukushima contaminated water. Second, information on nuclear energy was most often collected through the Internet, broadcasting, and SNS. Third, the higher the negative perception of nuclear power generation, the more negative the results were in terms of issues of concern following the discharge of contaminated water at the Fukushima nuclear power plant. Nuclear power cannot be separated from human life. Therefore, it is believed that accurate information and a knowledge delivery system are needed to ensure correct awareness of nuclear power generation.

• Journal of Korean Neurosurgical Society
• /
• v.67 no.4
• /
• pp.442-450
• /
• 2024

Objective : Cerebral hyperperfusion syndrome (CHS) manifests as a collection of symptoms brought on by heightened focal cerebral blood flow (CBF), afflicting nearly 30% of patients who have undergone superficial temporal artery (STA)-middle cerebral artery (MCA) anastomosis. The aim of this study was to investigate whether the amalgamation of magnetic resonance imaging (MRI) fluid-attenuated inversion recovery (FLAIR) and apparent diffusion coefficient (ADC) imaging via MRI can discern cerebral hyperemia after STA-MCA anastomosis surgery. Methods : A retrospective study was performed of patients who underwent STA-MCA anastomosis due to Moyamoya disease or atherosclerotic steno-occlusive disease. A protocol aimed at preventing CHS was instituted, leveraging the use of MRI FLAIR. Patients underwent MRI diffusion with FLAIR imaging 24 hours after STA-MCA anastomosis. A high signal on FLAIR images signified the presence of hyperemia at the bypass site, triggering a protocol of hyperemia care. All patients underwent hemodynamic evaluations, including perfusion MRI, single-photon emission computed tomography (SPECT), and digital subtraction angiography, both before and after the surgery. If a high signal intensity is observed on MRI FLAIR within 24 hours of the surgery, a repeat MRI is performed to confirm the presence of hyperemia. Patients with confirmed hyperemia are managed according to a protocol aimed at preventing further progression. Results : Out of a total of 162 patients, 24 individuals (comprising 16 women and 8 men) exhibited hyperemia on their MRI FLAIR scans following the procedure. SPECT was conducted on 23 patients, and 11 of them yielded positive results. All 24 patients underwent perfusion MRI, but nine of them showed no significant findings. Among the patients, 10 displayed elevations in both CBF and cerebral blood volume (CBV), three only showed elevation in CBF, and two only showed elevation in CBV. Follow-up MRI FLAIR scans conducted 6 months later on these patients revealed complete normalization of the previously observed high signal intensity, with no evidence of ischemic injury. Conclusion : The study determined that the use of MRI FLAIR and ADC mapping is a competent means of early detection of hyperemia after STA-MCA anastomosis surgery. The protocol established can be adopted by other neurosurgical institutions to enhance patient outcomes and mitigate the hazard of permanent cerebral injury caused by cerebral hyperemia.

• Korean Circulation Journal
• /
• v.53 no.12
• /
• pp.813-825
• /
• 2023

Background and Objectives: The prognostic implications of septic cardiomyopathy have not been clearly demonstrated. We evaluated serial changes in left ventricular (LV) and right ventricular (RV) function in patients with septic shock and their prognostic value on 7-day and in-hospital mortality. Methods: Transthoracic echocardiography was performed within 48 hours of the diagnosis of septic shock and 7 days after the initial evaluation. In addition to traditional echocardiographic parameters, LV and RV function was evaluated using global longitudinal strain (GLS), and tricuspid annular plane systolic excursion (TAPSE). Results: A total of 162 patients (men, 83, 51.5%; 70.7±13.4 years; Acute Physiology and Chronic Health Evaluation [APACHE] II, 30.6±9.2) were enrolled. Initial GLS and TAPSE were -14.9±5.2% and 16.9±5.5 mm, and improved in the follow-up evaluation (GLS, -17.6±4.9%; TAPSE, 19.2±5.4 mm). Seven-day and in-hospital mortality were 24 (14.9%) and 64 (39.8%). Seven-day mortality was significantly associated with initial GLS >-16% (odds ratio [OR], 14.066, 95% confidence interval [CI], 1.178-167.969, p=0.037) and APACHE II score (OR, 1.196, 95% CI, 1.047-1.365, p=0.008). The in-hospital mortality of 7-day survivors was associated with follow-up TAPSE <16 mm (OR, 10.109, 95% CI, 1.640-62.322, p=0.013) and Sequential Organ Failure Assessment score (OR, 1.340, 95% CI, 1.078-1.667, p=0.008). GLS was not associated with in-hospital mortality of 7-day survivors. Conclusions: Fluctuation of both ventricular function was common in septic shock. Seven-day mortality of patients with septic shock was related to GLS, whereas in-hospital mortality of 7-day survivors was related to TAPSE, not to GLS.

• Convergence Security Journal
• /
• v.24 no.2
• /
• pp.167-174
• /
• 2024

While reserve forces play a critical role in modern warfare, the primary focus on reserve forces has been on men. Women's reserve forces have received little attention. The purpose of this study is to examine the need to increase the number of women in the reserve and the impact of increasing the number of women on active duty. The reasons for the need for women in the military are the decrease in the resources of the reserve force as well as the regular force due to the decrease in population, the development of fields where women can perform missions with advantages due to the changing patterns of warfare, and the changing situation of gender equality and the increasing role of women in society. However, it is currently optional, not mandatory, for female veterans to join the Reserve. The number of cadres entering the reserve may decrease as the number of active-duty women increases. Using a 2018 estimate of 13.9 percent of women transitioning to the Reserve, 194 of the 1,402 projected transitioning women in '27 will transition to the Reserve. This leaves an estimated shortfall of 1,208 reserve officers and NCO. This suggests that the policy of increasing the number of women on active duty could have a significant impact on the reserve force in the future, and further policy research is needed.

• Industry Promotion Research
• /
• v.9 no.1
• /
• pp.123-132
• /
• 2024

The purpose of this study was to improve the understanding of stress coping in the very old and elderly and to improve life satisfaction through stress reduction as the population ages. To this end, this study aimed to test the mediating effect of social support on the relationship between stress coping and life satisfaction among very old people. In particular, we paid attention to the differences in stress coping from the existing elderly population and took the view that they should be studied as an independent group. To confirm this, we analysed 275 men and women aged 85 years and older who responded to the fifth supplementary survey of the National Elderly Security Panel (KReIS) conducted by the National Pension Service. IBM SPSS 26 was used to test the mediating effect of social support on the effect of stress coping measures on life satisfaction in the very old elderly. The results of the significance test of the independent variables on the mediating variable showed that stress coping was positively significant, i.e., the higher the level of stress coping, the higher the life satisfaction. In addition, the results of the significance test of the effects of the independent variables and mediators on the dependent variable showed that coping with stress had a significant effect, and the mediator, social support, also had a significant effect on life satisfaction. Therefore, this study suggests the need for social support to improve the level of life satisfaction through coping with stress in the very old elderly.

• Journal of the Korean Society of Radiology
• /
• v.83 no.2
• /
• pp.360-371
• /
• 2022

Purpose This study aimed to assess the factors influencing aortic unfolding (AU) defined by aortic width on coronary artery calcium (CAC) scan and determine the normal limits for AU. Materials and Methods In this retrospective study, we measured AU in 924 asymptomatic subjects who underwent CAC scanning during routine health screening from June 2015 to June 2018. Multivariate regression analysis was used to evaluate the factors influencing AU. After the exclusion of subjects with risk factors associated with AU, 283 subjects were included in the analysis of normal values of AU. Mean AU, standard deviation, and upper normal limit were calculated. Results Sex, age, CAC score, body mass index, body surface area, hypertension, left ventricular hypertrophy, plasma creatinine, and smoking were significantly associated with AU. The mean AU was 102.2 ± 12.8 mm for men and 93.1 ± 10.7 mm for women. AU increased with advancing age (9.6 mm per decade). Conclusion AU determined from a single measurement on CAC scans was associated with cardiovascular risk factors. The normal limits of AU were defined by age, sex, and body surface area in low-risk subjects in this study.

• Journal of the Korean Society of Radiology
• /
• v.81 no.3
• /
• pp.591-603
• /
• 2020

Purpose The purpose of this study was to describe the clinical features and chest computed tomography (CT) findings of coronavirus disease 2019 (COVID-19) pneumonia. Materials and Methods An Institutional Review Board-approved retrospective review was performed for 51 laboratory-confirmed COVID-19 pneumonia patients. Patients were divided into two groups depending on their clinical status: mild and severe. Clinical characteristics and chest CT findings were compared between the two groups. Results Among the 51 patients (22 men, 29 women; mean age, 56.5 ± 16 years; range, 22-88 years), 37 (72.5%) were in the mild group and 14 (27.5%) were in the severe group. The patients in the severe group (68.7 ± 12.5 years) were older than the patients in the mild group (51.8 ± 14.9 years, p < 0.001). Premorbid conditions and decreased lymphocyte counts were more often observed in the severe group than in the mild group (71% vs. 41%, p = 0.049 and 86% vs. 32%, p = 0.001, respectively). On chest CT, most patients exhibited a mixed ground-glass opacification (GGO) with consolidation (76%) or a GGO (22%) pattern. The majority of lesions were predominantly bilateral in the lower lung with a posterior, peripheral distribution. The patients in the severe group had higher severity scores than those in the mild group. Conclusion Patients with laboratory-confirmed COVID-19 pneumonia have typical chest CT findings that provide important information regarding expected disease severity.

• Korean Journal of Radiology
• /
• v.23 no.5
• /
• pp.548-554
• /
• 2022

Objective: To evaluate the safety and feasibility of prostatic artery embolization (PAE) via transradial access (TRA) compared with transfemoral access (TFA). Materials and Methods: This retrospective study included 53 consecutive men with lower urinary tract symptoms (LUTS) who underwent PAE between September 2018 and September 2021. Thirty-one patients (mean age ± standard deviation: 70.6 ± 8.4 years) were treated with TFA, including 14 patients treated before adopting TRA. Since December 2019, TRA has also been attempted with the procedure's selection criteria of patent carpal circulation and a height ≤ 172 cm, with 22 patients treated via TRA (69.1 ± 9.6 years). Parameters of technical success (defined as successful bilateral embolization), clinical success (defined as LUTS improvement), procedural time, radiation dose, and adverse events were compared between the two groups using the Fisher's exact test, independent sample t test, Wilcoxon signed-rank test, or Mann-Whitney test. Results: All patients received at least one-side PAE. Technical success of PAE was achieved in most patients (TRA, 21/22; TFA, 30/31; p > 0.999). No technical problem-related conversion from TRA to TFA occurred. The clinical success rate was 85% (11/13) in patients with TRA, and 89% (16/18) in patients with TFA for follow-up > 2 weeks post-PAE (median, 3 months) (p > 0.999). The median procedure time was similar in both groups (TRA, 81 minutes vs. TFA, 94 minutes; p = 0.570). No significant dose differences were found between the TRA and TFA groups in the dose-area product (median Gycm², 95 [range, 44-255] for TRA and 84 [34-255] for TFA; p = 0.678) or cumulative air kerma (median mGy, 609 [236-1584] for TRA and 634 [217-1594] for TFA; p = 0.551). No major adverse events occurred in either of the groups. Conclusion: PAE via TRA is a safe and feasible method comparable to conventional TFA. It can be safely implemented by selecting patients with patent carpal circulation and adequate height.

• Korean Journal of Radiology
• /
• v.23 no.9
• /
• pp.911-920
• /
• 2022

Objective: ⁶⁸Ga-NGUL is a novel prostate-specific membrane antigen (PSMA)-targeting tracer based on Glu-Urea-Lys derivatives conjugated to a 1,4,7-triazacyclononane-N,N',N''-triacetic acid (NOTA) chelator via a thiourea-type short linker. This phase I clinical trial of ⁶⁸Ga-NGUL was conducted to evaluate the safety and radiation dosimetry of ⁶⁸Ga-NGUL in healthy volunteers and the lesion detection rate of ⁶⁸Ga-NGUL in patients with prostate cancer. Materials and Methods: We designed a prospective, open-label, single-arm clinical trial with two cohorts comprising six healthy adult men and six patients with metastatic prostate cancer. Safety and blood test-based toxicities were monitored throughout the study. PET/CT scans were acquired at multiple time points after administering ⁶⁸Ga-NGUL (2 MBq/kg; 96-165 MBq). In healthy adults, absorbed organ doses and effective doses were calculated using the OLINDA/EXM software. In patients with prostate cancer, the rates of detecting suspicious lesions by ⁶⁸Ga-NGUL PET/CT and conventional imaging (CT and bone scintigraphy) during the screening period, within one month after recruitment, were compared. Results: All 12 participants (six healthy adults aged 31-32 years and six prostate cancer patients aged 57-81 years) completed the clinical trial. No drug-related adverse events were observed. In the healthy adult group, ⁶⁸Ga-NGUL was rapidly distributed, with the highest uptake in the kidneys. The median effective dose coefficient was calculated as 0.025 mSv/MBq, and cumulative activity in the bladder had the highest contribution. In patients with metastatic prostate cancer, 229 suspicious lesions were detected using either ⁶⁸Ga-NGUL PET/CT or conventional imaging. Among them, ⁶⁸Ga-NGUL PET/CT detected 199 (86.9%) lesions and CT or bone scintigraphy detected 114 (49.8%) lesions. Conclusion: ⁶⁸Ga-NGUL can be safely applied clinically and has shown a higher detection rate for the localization of metastatic lesions in prostate cancer than conventional imaging. Therefore, ⁶⁸Ga-NGUL is a valuable option for prostate cancer imaging.