• Title/Summary/Keyword: MET1

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A Association between Physical Activity and Risk of Breast Cancer (신체활동량과 유방암 발생과의 관계)

  • Kim, Myeong-Seong;Nam, Young-Hee
    • The Journal of the Korea Contents Association
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    • v.20 no.3
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    • pp.671-677
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    • 2020
  • The number one female cancer in Korea is breast cancer, and the incidence rate continues to increase. There are many opinions that this is due to the impact of increased sedentary life along with economic growth. In this study, the international standard exercise status questionnaire was administered to patients and normal group who visited to the specialized cancer hospital in Korea, and to standardized scores of the exercise status (MET score) obtained from questionnaire were used to compare the impaction on breast cancer risk and difference of the MET score between the patients and control group. The ages of the study subjects were selected as subjects without statistical differences between the patients group and the normal group. also done with survey the family history, BMI, the menarche, age at birth of first child, the degree of education to exclude impaction on breast cancer risk depending on physical activity. In general, the breast cancer patients showed lower MET scores than the normal group, and the effect of activity on breast cancer was greater in post-menopausal women than in pre-menopausal women. Also BMI was similar to breast cancer risk. Maintaining proper weight through exercise can reduce the accumulation of carcinogens in breast cancer in the body, thereby reducing the incidence of breast cancer.

Ileal Digestibility of Amino Acids in Meat Meal and Soybean Meal Fed to Growing Pigs

  • Kong, C.;Kang, H.G.;Kim, B.G.;Kim, K.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.7
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    • pp.990-995
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    • 2014
  • The objective of this experiment was to determine the concentration and digestibility of crude protein (CP) and amino acid (AA) in meat meal (MM), and to compare these values with the respective values in soybean meal (SBM). Six barrows (initial body weight = $66.9{\pm}3.8kg$) surgically fitted with a T-cannula at the distal ileum were allotted to a replicated $3{\times}3$ balanced Latin square design with 3 diets and 3 periods. Two experimental diets containing test ingredients as the sole source of AA were prepared to estimate the apparent ileal digestibility (AID) for CP and AA by the direct method. An N-free diet was also prepared to estimate basal endogenous losses of CP and AA. All experimental diets contained 5% chromic oxide as an indigestible index. Each period consisted of a 5-d adaptation period and a 2-d of ileal digesta collection period. Ileal digesta samples were collected from 0900 to 1700 on d 6 and 7 of each period. The concentrations of CP, Lys, Met, and Trp in MM and SBM were analyzed to be 64.1, 3.5, 1.1 and 0.6, and 45.6, 2.8, 0.8, and 0.3%, respectively. The AID of all AA except Gly in MM was less (p<0.05) than in SBM. The AID of Lys, Met, and Trp in MM was estimated to be 56.0, 71.7, and 47.1%, respectively. The SID of all AA in MM was less (p<0.05) than in SBM. The SID of Lys, Met, and Trp was 65.1, 79.2, and 78.5%, respectively. In conclusion, the CP and AA contents in MM were greater than those in SBM whereas the ileal digestibility of all AA in MM was less than in SBM.

Influences of Sarcopenic and Non-sarcopenic Obesity on the Components of Metabolic Syndrome in Adolescents (청소년의 근감소성 비만과 비근감소성 비만이 대사증후군 구성요소에 미치는 영향)

  • Park, Hyunju
    • Journal of Korean Biological Nursing Science
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    • v.19 no.4
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    • pp.266-275
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    • 2017
  • Purpose: The purpose of this study was to investigate the influences of sarcopenic and non-sarcopenic obesity on the components of Metabolic Syndrome (MetS) in adolescents. Methods: This study used the fifth Korean National Health and Nutrition Examination Survey data from 2010 to 2011. The study included 859 adolescents aged 12 to 18 years. Descriptive statistics and simple and multiple logistic regression analyses were conducted using SAS 9.2. Results: Based on the results, adolescents with sarcopenic obesity had a higher risk of central obesity (AOR: 23.41, 95% CI: 12.76-43.97), high triglyceride (OR: 4.58, 95% CI: 2.69-7.79), low HDL-cholesterol (AOR: 2.66, 95% CI: 1.74-4.05), high blood pressure (AOR: 3.44, 95% CI: 1.37-8.68), and high fasting glucose (AOR: 2.37, 95% CI: 1.13-4.96) than their normal counterparts. Adolescents with non-sarcopenic obesity had a higher risk of central obesity (AOR: 19.75, 95% CI: 9.73-44.67), high triglyceride (OR: 3.09, 95% CI: 1.22-7.81), and low HDL-cholesterol (AOR: 2.73, 95% CI: 1.37-5.45) than normal youths, and these were not significantly related to high blood pressure and fasting glucose. Conclusion: Sarcopenic obesity was more related to the components of MetS than non-sarcopenic obesity. Since adolescents with sarcopenic obesity are a more vulnerable population, a prevention and management program for MetS and cardiovascular risk should be implemented in this population.

Clustering Patterns and Correlates of Multiple Health Behaviors in Middle-aged Koreans with Metabolic Syndrome

  • Jeon, Janet Ye-Won;Yoo, Seung-Hyun;Kim, Hye-Kyeong
    • Korean Journal of Health Education and Promotion
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    • v.29 no.2
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    • pp.93-105
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    • 2012
  • Objectives: The objective of the study was to examine the clustering patterns and correlates of multiple health behaviors (MHBs) in middle-aged Koreans with metabolic syndrome (MetS). Methods: Data on sociodemographics, clinical characteristics, health behaviors (vegetable intake, physical activity, cigarette smoking, and alcohol consumption), and psychological characteristics were collected by a self-reported survey and medical examination from 331 individuals with MetS. Clustering of MHBs was examined by measuring 1) the ratios of observed and expected prevalence of MHBs, and 2) the prevalence odds ratios. A binomial logistic regression were conducted. Results: Men were more likely than women to engage in multiple unhealthy behaviors. Clustering of smoking and heavy drinking was exhibited in the participants. Women with high vegetable intake were more likely to be physically inactive, and those with inadequate vegetable intake were more likely to be physically active. Those with lower self-regulation were more likely to engage in unhealthy behaviors. Conclusions: The findings support the multiple health behavior approach as opposed to the individual health behavior approach. Emphasis of self-regulation is necessary in developing multiple behavior intervention for individuals with MetS.

A Clinical Case of Muscle Energy Technique and Schroth Method for Idiopathic Scoliosis (근에너지기법(Muscle Energy Technique)과 Schroth Method를 이용한 특발성 척추 측만증 호전 1례)

  • Lee, Sung-Joon;Park, Jae-Hyun;Nam, Su-Hyeon;Kang, Jun-Hyuk
    • Journal of Korean Medicine Rehabilitation
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    • v.24 no.3
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    • pp.173-179
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    • 2014
  • The purpose of this study is to report the effect of muscle energy technique (MET) and Schroth method on idiopathic scoliosis. A patient with idiopathic scoliosis was treated by MET and Schroth method. To investigate the outcome of the patient's improvement, we observed the X-ray of cervical, thoracic, lumbar spine. And Cobb's angle, correctability, visual analog scale (VAS) were used to measure changes during treatment. After treatment, Cobb's angle and correctability, VAS were improved significantly. MET and Schroth method are proved to be helpful to improve idiopathic scoliosis. And, further studies will be needed.

A New Process for Liquid Phase Sintering of W-Cu Composite; Fluidized Beds Reductio Method (W-Cu 합금의 액상소결을 위한 새로운 공정의 개발:유동층 환원법)

  • Ihn, Tae-Hyoung;Lee, Seok-Woon;Joo, Seung-Ki
    • Korean Journal of Materials Research
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    • v.4 no.4
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    • pp.393-400
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    • 1994
  • A new process for uniform coating of copper to submicron tungsten powder has been developed. W-Cu alloy where copper can be uniformly distibuted has been made by the liquid phase sintering of thus prepared tungsten powder. It has been found that copper content can be lowered less than IOwt. % in our new process, maintaining the uniform distribution of copper in W-Cu alloy. Relative density above 96% was obtained after the liquid phase sintering when small amount of cobalt was added. It was revealed that the rapid increase of densification rate was due to the enhancement of wettability between tungsten particle and liquid copper.

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O-Methyltransferases from Arabidopsis thaliana

  • Kim, Bong-Gyu;Kim, Dae-Hwan;Hur, Hor-Gil;Lim, Jun;Lim, Yoong-Ho;Ahn, Joong-Hoon
    • Journal of Applied Biological Chemistry
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    • v.48 no.3
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    • pp.113-119
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    • 2005
  • O-methylation mediated by O-methyltransferases (OMTs) is a common modification in natural product biosynthesis and contributes to diversity of secondary metabolites. OMTs use phenylpropanoids, flavonoids, other phenolics and alkaloids as substrates, and share common domains for S-adenosyl-L-methionine (AdoMet) and substrate binding. We searched Arabiposis genome and found 17 OMTs genes (AtOMTs). AdoMet- and substrate-binding sites were predicted. AdoMet binding domain of AtOMTs is highly conserved, while substrate-binding domain is diverse, indicating use of different substrates. In addition, expressions of six AtOMT genes in response to UV and in different tissues were investigated using real-time quantitative reverse transcriptase-polymerase chain reaction. All the AtOMTs investigated were expressed under normal growth condition and most, except AtOMT10, were induced after UV illumination. AtOMT1 and AtOMT8 were expressed in all the tissues, whereas AtOMT10 showed flower-specific expression. Analysis of these AtOMT gene expressions could provide some clues on AtOMT involvement in the cellular processes.

Identification of Mutations in Protein Kinase CKIIβ Subunit That Affect Its Binding to Ribosomal Protein L41 and Homodimerization

  • Ahn, Bong-Hyun;Lee, Ji-Hoon;Bae, Young-Seuk
    • BMB Reports
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    • v.36 no.4
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    • pp.344-348
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    • 2003
  • Protein kinase CKII is composed of two catalytic ($\alpha$ or $\alpha$') subunits and two regulatory ($\beta$) subunits. The $CKII{\beta}$ subunit is thought to mediate the tetramer formation and interact with other target proteins. However, its physiological function remains obscure. In this study, point mutants of $CKII{\beta}$ that are defective for the L41 binding were isolated by using the reverse two-hybrid system. A sequence analysis of the point mutants revealed that Asp-26, Met-52, and Met-78 of $CKII{\beta}$ are critical for L41 binding; Asn-67 (and/or Lys-139) and Met-52 are important for $CKII{\beta}$ homodimerization. Two point mutants, R75 and R83, of $CKII{\beta}$ interacted with L5, topoisomerase $II{\beta}$, and CKBBP1/SAG, but not with the wild-type $CKII{\beta}$. This indicates that $CKII{\beta}$ homodimerization is not a prerequisite for its binding to target proteins. These $CKII{\beta}$ point mutants may be useful in exploring the biochemical physiological functions of $CKII{\beta}$.

The Quality of a Traditional Dietary Pattern in Relation to Metabolic Syndrome in Elderly South Koreans

  • Oh, Chorong;No, Jaekyung
    • Journal of Obesity & Metabolic Syndrome
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    • v.27 no.4
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    • pp.254-261
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    • 2018
  • Background: The most beneficial dietary pattern in managing metabolic syndrome (MetS) in the elderly has not been ascertained. The aim of this study is to classify dietary patterns and to examine associations between dietary pattern, MetS and body composition in elderly Koreans. Methods: This study was conducted among Koreans 65 years or older using data from the Korea National Health and Nutrition Examination Survey in 2009. A total of 1,567 study subjects were included. All statistical analyses were conducted using SPSS version 20.0 and dietary patterns were classified by cluster analysis. Results: There were three dietary patterns derived by cluster analysis in this study. We observed that most South Korean elderly still maintain a traditional dietary pattern. Dietary patterns were classified as balanced (31%), imbalanced (40%), or very imbalanced (30%), with the majority of subjects having an unbalanced diet pattern in which their total energy and nutrient intake was insufficient compared with the Dietary Reference Intake for Koreans. Those in the very imbalanced group had a ratio of macronutrients (carbohydrates:fats:protein) of 81.15:7.18:11.50 and a 54% higher likelihood of having hypertriglyceridemia (P=0.025) compared with those in the balanced group. Conclusion: The current findings indicate that the diets of South Korean elderly are nutritionally imbalanced, including high carbohydrate consumption, which confers a high risk hypertriglyceridemia. These findings highlight the effect of nutritional imbalance in elderly with MetS.

Evaluation of the maneuverability of the fisheries training ship Baek-Kyung (실습선 백경호의 조종성능 평가)

  • Chun-Ki LEE;Kyung-Jin RYU;Yoo-Won LEE;Su-Hyung KIM
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.60 no.2
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    • pp.179-185
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    • 2024
  • The model ship of this study, the Baek-Kyung fisheries training ship of Pukyong National University, has a length between perpendiculars of 85 meters, making it not subject to the IMO maneuverability standards. However, understanding the maneuvering characteristics of the vessel is essential for safe navigation. In this regard, this study was conducted to analyze the results from the sea trials of the model ship conducted in accordance with the IMO maneuverability standards. The results of the turning tests met the standards well while in the zig-zag tests, the first overshoot angle exceeded the standard in the 10°/10° test; however, such results met with a difference of 1.8° in the 20°/20° test. Additionally, using the course-stability discrimination formula, the calculated value was -0.0051, indicating unstable course-stability. The results of the stopping tests met the standards well. It is hoped that the analyzed maneuvering characteristics of the model ship from the study results will contribute to the safety of ship navigation.