• Title/Summary/Keyword: MDI

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Analysis of Pine Nut Oil Composition and Its Effects on Obesity (잣기름 성분분석 및 비만 예방효과 연구)

  • Kim, Kyoung Kon;Kang, Yun Hwan;Kim, Dae Jung;Kim, Tae Woo;Choe, Myeon
    • Korean Journal of Food Science and Technology
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    • v.46 no.5
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    • pp.630-635
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    • 2014
  • Pine nut oil (PNO) is well known to impart beneficial effects in overweight individuals, but the mechanisms underlying PNO-mediated weight loss remain unclear. To investigate how PNO promotes weight loss, its composition was determined by gas chromatography coupled with mass spectrometry (GC-MS). In addition, the effects of PNO on cytotoxicity, lipid accumulation, expression of lipid metabolism-related biomarkers, and leptin secretion were assessed in 3T3-L1 cells. GC-MS analyses revealed that PNO contains several components, including linoleic acid, oleic acid, palmitic acid, and stearic acid. Moreover, PNO did not have a cytotoxic effect on 3T3-L1 cells. However, it inhibited the expression of peroxisome proliferator-activated receptor (PPAR) and adipocyte protein 2 (aP2). Finally, PNO significantly increased leptin secretion in a dose-dependent manner. Taken together, these results support the notion that PNO is useful for weight management in overweight individuals.

Studies of Annealing Effect on the Properties of the Rigid Polyurethane (열처리에 따른 경질 폴리우레탄의 물성 변화 연구)

  • Kang S. J.;Jung H. C.;Kim W. N.;Lee Y. B.;Choe K. H.;Hong S. H.;Kim S. B.
    • Journal of the Korean Institute of Gas
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    • v.2 no.4
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    • pp.18-24
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    • 1998
  • Polyurethane (PU) synthesized from 4,4'-diphenylmethane diisocyanate having high functionality (f=2.9) and polyester polyol have been investigated by differential scanning calorimeter (DSC), dynamic mechanical thermal analyzer (DMTA), and Fourier transform infrared spectroscope (FT-IR). From the DSC measurement of polyurethane, a single transition temperature ($T_g$) was observed. This result indicates that polyurethanes synthesized in this work have homogeneous network structure due to high functionality of diisocyanate. It was also found that the $T_g$ of polyurethane was increased as hard segment content was increased. The results from DMTA measurement are consistent with DSC results. In order to investigate the effect of thermal annealing on the $T_g$ of polyurethane, the samples were annealed at various annealing conditions. $T_gs$ of polyurethanes were found to increased with annealing temperature. From swelling experiment and FT-IR studies, it was found that the $T_g$ was increased as crosslinking density of polyurethane was increased.

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Preparation and Properties of DMF-Based Polyurethanes Containing Bio-Polyol/Ester-Polyol for Wet-Type Polyurethane Artificial Leather (습식 인조피혁용 바이오 폴리올/폴리에스터 폴리올을 함유한 DMF 기반 폴리우레탄의 제조 및 물성)

  • Sur, Suk-Hun;Choi, Pil-Jun;Ko, Jae-Wang;Park, Ji-Hyeon;Lee, Jae-Yeon;Lee, Young-Hee;Kim, Han-Do
    • Clean Technology
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    • v.25 no.1
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    • pp.7-13
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    • 2019
  • Recently, attention has been paid to obtaining bio-polyols from renewable resources. Successful use of these natural ingredients successfully produced in the industry for the synthesis of various polyurethanes is a very important task. In this study, a series of dimethylformamide (DMF) based polyurethanes were synthesized from methylene diphenyl diisocyanate (MDI)/1, 4-butanediol and bio-polyol (polytrimethylene ether glycol based on 1, 3-propanediol : B-POL)/polyester polyol (polyadipate diol based on 1,4-butandiol : H-PET). The effect of different ratio of bio-polyol (B-POL)/polyester polyol (H-PET) on the physical properties of polyurethane was investigated. As the B-POL content in B-POL/H-PET mixture increased, the glass transition of soft segment (Tgs) and tensile strength of polyurethane decreased, however, the elongation at break and tear strength increased. On the other hand, artificial leather was produced by wet process using synthesized DMF-based polyurethanes. It was found that there was almost no difference in the effect of the B-POL/H-PET composition on the average size and density (the number of cells per unit volume) of the porous cells formed in artificial leather. These results show that there is no problem in using bio-polyol (B-POL) based polyurethane for artificial leather produced by wet process.

Extract of Ranunculus sceleratus Reduced Adipogenesis by Inhibiting AMPK Pathway in 3T3-L1 Preadipocytes (3T3-L1 전구지방세포에서 개구리자리(Ranunculus sceleratus) 추출물의 AMPK 신호전달을 통한 지방생성 억제 효과)

  • Kim, Yae-Ji;Cho, Sung-Pil;Lee, Hui-Ju;Hong, Geum-Lan;Kim, Kyung-Hyun;Ryu, Si-Yun;Jung, Ju-Young
    • Journal of Korean Medicine for Obesity Research
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    • v.22 no.1
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    • pp.30-37
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    • 2022
  • Objectives: Adipogenesis is the process by which pre-adipocytes are differentiated into adipocytes. It also plays an important role in adipocyte formation and lipid accumulation. Ranunculus sceleratus (R. sceleratus) extracts are used for the treatment of various diseases such as hepatitis, jaundice, and tuberous lymphadenitis in oriental medicine. However, its effect on adipogenesis has not yet been studied. In this study, we investigated the effects of R. sceleratus on adipogenesis in 3T3-L1 cells. Methods: Cells were treated with 50, 100, and 200 ㎍/ml of R. sceleratus and cell viability was evaluated. To differentiate the 3T3-L1 preadipocytes, a 3-isobutyl-1-methylxanthine, dexamethasone, and insulin (MDI) solution were used. The accumulation of lipid droplets was determined by Oil Red O staining. The expression levels of adipogenesis-related proteins were also determined. Results: MDI solution differentiated the preadipocytes into adipocytes and accumulation of lipids was observed in the differentiated 3T3-L1 cells. Interestingly, the amount of lipid droplets was reduced after R. sceleratus treatment. In addition, the expression levels of key adipogenic transcription factors, such as CCAAT/enhancer-binding proteins-𝛼 (C/EBP-𝛼) and peroxisome proliferator-activated receptors-𝛾 (PPAR-𝛾) were also reduced after R. sceleratus treatment. Furthermore, R. sceleratus increased AMP-activated kinase (AMPK) phosphorylation and decreased sterol regulatory element-binding protein-1 expression. Conclusions: Our results showed that R. sceleratus reduced preadipocyte differentiation by inhibiting C/EBP-𝛼 and PPAR-𝛾 levels via the AMPK pathway. Therefore, we suggest that R. sceleratus may be potentially used as an anti-adipogenic agent.

Molecular Design of Water-dispersed Polymer Binder with Network Structure for Improved Structural Stability of Si-based Anode (실리콘 기반 음극의 구조적 안전성 향상을 위한 가교 구조를 가지는 수분산 고분자 바인더의 분자 구조 설계)

  • Eun Young Lim;Eunsol Lee;Jin Hong Lee
    • Applied Chemistry for Engineering
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    • v.35 no.4
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    • pp.309-315
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    • 2024
  • Silicon and carbon composite (SiC) is considered one of the most promising anode materials for the commercialization of Si-based anodes, as it could simultaneously satisfy the high theoretical capacity of Si and the high electronic conductivity of carbon. However, SiC active material undergoes repeated volumetric changes during charge/discharge processes, leading to continuous electrolyte decomposition and capacity fading, which is still considered an issue that needs to be addressed. To solve this issue, we suggest a 4,4'-Methylenebis(cyclohexyl isocyanate) (H12MDI)-based waterborne polyurethane binder (HPUD), which forms a 3D network structure through thermal cross-linking reaction. The cross-linked HPUD (denoted as CHPU) was prepared using an epoxy ring-opening reaction of the cross-linker, triglycidyl isocyanurate (TGIC), via simple thermal treatment during the SiC anode drying process. The SiC anode with the CHPU binder, which exhibited superior mechanical and adhesion properties, not only demonstrated excellent rate and cycling performance but also alleviated the volume expansion of the SiC anode. This work implies that eco-friendly binders with cross-linked structures could be utilized for various Si-based anodes.

발명하는 사람들-제54호

  • Han, Mi-Yeong
    • The Inventors News
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    • no.54
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    • pp.1-16
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    • 2007
  • 한국여성경제단체연합, 여성경제계 위해 공식 출범/발행인 칼럼/'마드리드 출원제도' 적극 활용 상표 침해 줄여라/일본 특허출원 심사기간 단축된다/기업.연구소 신입사원75%, 특허 관련 지식 전무/'주몽'이계인 씨 산자부 홍보대사 위촉/특허등록세, 신청 다음날 내도 된다/특허청, 6시그마 공공부문 혁신 주도/아듀 2006 한국여성발명협회 결산/자문위원 칼럼/로봇시장에도 브랜드 선점 열풍/농산물도 발명특허 상표 등록 시대/도소매업도 서비스업으로 출원 가능/기름대신 물 사용한 자동차, 항공기 현실화/반도체 배선 기술 특허 출원 상승세/자동차는 모바일 엔터네이너/'적외선 감지기술' 우리 생활속으로/서울반도체.바론테크, 일본 특허분쟁 승소/하나TV, 특허권 침해 피소/삼성전자, 분쟁.경쟁 대응위해 특허조직 통합/신한다이아몬드 일본 MDI 특허분쟁 승소/미니인터뷰/나노기술 응용한 디스플레이 특허출원 급증/미국의 두 배인 '휴면 특허', 대책 마련 시급/특허법원 "사용횟수 적다고 상표취소 못해"/종자번식 유전자 변형식물도 특허출원 가능/변리사 1차 시험 합격자 대폭 축소/역사 속의 발명품/하루 10분 발명교실/특허Q&A/신년인터뷰/화장하는 방법도 특허 받는다/'취업에서 결혼까지' 올인원 시스템 화제/아이디어 착상 및 발명 기법/아줌마의 힘이 발휘될 때까지 발명 또 발명/버뱅크의 식물 품종 개량/미국 청년, 몸짱 선탠용 티셔츠 발명/스위스, 국가경쟁력 1위의 비밀/저지방식,'유방암' 제발 위험 감소/서울대, 세계최초 암캐 복제 성공/국가 R&D 특허조사, 전체 R&D 부처로 확대/전국 초.중생 발명 글짓기.만화현상 공모전/특허청, 공공부문 성과주의 대통령상/한국여성발명협회 회원사 발명품 가이드

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Effect of Polyethylene Glycol Molecular Weight and NCO Index on Properties of the Hydrophilic Reactive Hotmelt Polyurethane Adhesives (Polyethylene Glycol의 분자량 및 NCO index의 변화에 따른 Hydrophilic Reactive Hotmelt Polyurethane의 물성 변화)

  • Han, Young Chul;Kim, Dack Han;Oh, Kyung Seok;Shin, Hyeon Jeong;Yang, Jeong Han;Jeong, Han Mo
    • Textile Coloration and Finishing
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    • v.30 no.2
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    • pp.90-97
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    • 2018
  • Hydrophilic reactive hot-melt polyurethane adhesive(HRHA) using a hydrophilic polyol having different molecular weight and NCO index was synthesized. This HRHA was synthesized using Polyethylene glycol(PEG) as a hydrophilic polyol, Polypropylene glycol(PPG) and Polycaprolactone diol(PCL) as hydrophobic polyols, and Methylene diphenyl diisocyanate(MDI) as an isocyanate. The changes in IR spectrum, viscosity and thermal properties of HRHA with different PEG molecular weights and NCO index were investigated, and the tensile strength and elongation of the HRHA casting film and the peel strength, moisture permeability and water pressure of the HRHA coated fabric were confirmed. In this experiment, as the molecular weight of PEG and NCO index increased, the adhesive strength, tensile strength, elongation and moisture permeability was increased but viscosity and Tg was decreased.

On Mode Correlation of Solar Acoustic Oscillations

  • Chang, Heon-Young
    • Journal of Astronomy and Space Sciences
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    • v.26 no.3
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    • pp.287-294
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    • 2009
  • In helioseismology it is normally assumed that p-mode oscillations are excited in a statistically independent fashion. Unfortunately, however, this issue is not clearly settled down in that two experiments exist, which apparently look in discrepancy. That is, Appourchaux et al. (2000) looked at bin-to-bin correlation and found no evidence that the assumption is invalid. On the other hand, Roth (2001) reported that p-mode pairs with nearby frequencies tend to be anti-correlated, possibly by a mode-coupling effect. This work is motivated by an idea that one may test if there exists an excess of anticorrelated power variations of pairs of solar p-modes. We have analyzed a 72-day MDI spherical-harmonic time series to examine temporal variations of p-mode power and their correlation. The power variation is computed by a running-window method after the previous study by Roth (2001), and then distribution function of power correlation between mode pairs is produced. We have confirmed Roth's result that there is an excess of anti-correlated p-mode pairs with nearby frequencies. On the other hand, the amount of excess was somewhat smaller than the previous study. Moreover, the distribution function does not exhibit significant change when we paired modes with non-nearby frequencies, implying that the excess is not due to mode coupling. We conclude that the origin of this excess of anticorrelations may not be a solar physical process, by pointing out the possibility of statistical bias playing the central role in producing the excess.

Variation in Solar Limb Darkening Coefficient Estimated from Solar Images Taken by SOHO and SDO

  • Moon, Byeongha;Jeong, Dong-Gwon;Oh, Suyeon;Sohn, Jongdae
    • Journal of Astronomy and Space Sciences
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    • v.34 no.2
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    • pp.99-103
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    • 2017
  • The sun is not equally bright over the whole sphere, but rather is darkened toward the limb. This effect is well-known as limb darkening. The limb darkening coefficient is defined by the ratio of the center intensity to limb intensity. In this study, we calculate the limb darkening coefficient using the photospheric intensity estimated from solar images taken by solar and helispheric observatory (SOHO) and solar dynamics observatory (SDO). The photospheric intensity data cover almost two solar cycles from May 1996 to December 2016. The limb darkening coefficient for a size of 0.9 diameter is about 0.69 and this value is consistent with solar limb darkening. The limb darkening coefficient estimated from SOHO shows a temporal increase at solar maximum and a gradual increase since the solar minimum of 2008. The limb darkening coefficient estimated from SDO shows a constant value of about 0.65 and a decreasing trend since 2014. The increase in the coefficient reflects the effect of weakened solar activity. However, the decrease since 2014 is caused by the aging effect.

Dynamic Modulus of Three-Layer Boards with Different Furnish and Shelling Ratio

  • Rofii, Muhammad Navis;Prayitno, Tibertius Agus;Suzuki, Shigehiko
    • Journal of the Korean Wood Science and Technology
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    • v.44 no.2
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    • pp.274-282
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    • 2016
  • This aims of this study were to investigate the relationship between non-destructive evaluation (NDE) and actual bending properties of particleboard, and to predict the bending properties of three-layer particleboard. Three kinds of raw materials, i.e. Hinoki (Chamaecyparis obtusa Endl.) strand, knife-milled Douglas-fir (Pseudotsuga manziesii (Mirb) Franco), and hammer-milled matoa (Pometia spp.) obtained from wooden industry, were utilized as furnish for experimental panel with methylene diphenyl diisocyanate (MDI) resin as binder. The NDE test was conducted by hit sounds using an FFT analyzer according to the spectrum peak of wave frequency, while the static bending test was conducted according to JIS A-5908. The results reveal that the dynamic Young's modulus as an NDE test has a potential for being used to predict the elastic bending of particleboards by a specific equation for adjusting its proper values. The values of NDE and static test are significantly different with a deviation range at 3-20%. The bending stiffness of three-layer particleboards manufactured from different wood species is predictable by observing the bending stiffness of two elements based on the thickness of its layers. The predicted values of bending stiffness and static test are significantly different with a deviation range at 5-24%.