• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권5호
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• pp.411-422
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• 2020

With the increasing number of children with inflammatory bowel disease (IBD), very early-onset IBD (VEO-IBD), defined as IBD that is diagnosed or that develops before 6 years of age, has become a field of innovation among pediatric gastroenterologists. Advances in genetic testing have enabled the diagnosis of IBD caused by gene mutations, also known as monogenic or Mendelian disorder-associated IBD (MD-IBD), with approximately 60 causative genes reported to date. The diagnosis of VEO-IBD requires endoscopic and histological evaluations. However, satisfactory small bowel imaging studies may not be feasible in this small population. Both genetic and immunological approaches are necessary for the diagnosis of MD-IBD, which can differ among countries according to the available resources. As a result of the use of targeted gene panels covered by the national health insurance and the nationwide research project investigating inborn errors of immunity, an efficient approach for the diagnosis of MD-IBD has been developed in Japan. Proper management of VEO-IBD by pediatric gastroenterologists constitutes a challenge. Some MD-IBDs can be curable by allogenic hematopoietic stem cell transplantation. With an understanding of the affected gene functions, targeted therapies are being developed. Social and psychological support systems for both children and their families should also be provided to improve their quality of life. Multidisciplinary team care would contribute to early diagnosis, proper therapeutic interventions, and improved quality of life in patients and their families.

• 대한화학회지
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• 제64권5호
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• pp.259-266
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• 2020

The main purpose of this study is to examine the different physicochemical properties of spray-dried products. The carrier agents and powders after the spray-drying process were analyzed for encapsulation yield, moisture content, color parameters, total polyphenol content (TPC), antioxidant capacity (AC), bulk density, flowability, wettability, hygroscopicity, water solubility index (WSI), particle size and microstructure. The spray-drying process was carried out with different carrier agents including maltodextrin (MD) and the combination of maltodextrin and gum arabic (MD-GA) with MA/GA ratio of 70/30, dried at the inlet/outlet air temperature of 160 ℃/70 ℃, 4 bar, airflow rate of 70 ㎥·h^-1 and feed flow rate of 750 mL·h^-1. The results showed that the different carrier agents have significant influences on the physicochemical properties of the powder produced by the spray-drying method. In there, while the values of recovery efficiency and flowability of spray-dried products from MD are higher than those of spray-dried products from MD-GA combination, the opposite is true for the values of TPC, AC, bulk density and wettability, whereas hygroscopicity and WSI values are equally represented in both products.

• Membrane and Water Treatment
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• 제5권3호
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• pp.197-205
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• 2014

For the first time in Bangladesh, a bench scale membrane bioreactor (MBR) unit was tested in treating a textile wastewater in the industry premises of EOS Textile Mills LTD, Dhaka for three months. The performance of the unit was compared with that of the conventional activated sludge treatment plant, which is in operation in the same premises. The COD and BOD removal efficiency of the MBR unit reached to around 90% and 80% respectively in 20 days whereas the removal efficiency of the conventional treatment plant was as low as 40-50% and 38-40% respectively. The outlet COD and the BOD level for the MBR unit remained stable in spite of the fluctuation in the feed value, while the conventional effluent treatment plant (ETP) failed to keep any stabilized level. The performance of the MBR unit was much superior to that of the functional ETP and the water treated by the MBR system can meet disposal standard.

• The Journal of Korean Physical Therapy
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• 제24권6호
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• pp.388-392
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• 2012

Purpose: Muscle imbalance between upper trapezius (UT) and serratus anterior (SA) during arm elevation is a factor causing shoulder dysfunction. However, there is no study to compare the muscle activities of the UT and middle deltoid (MD). The purpose of this study was to compare the muscle activities of the UT and MD between with and without elevation of shoulder girdle (ESG) during shoulder abduction. Methods: The subjects without (control group=9) or with (ESG group=8) participated in this study. The muscle activities of the UT and MD were measured using a electromyography during $90^{\circ}$ shoulder abducted position in both group. The data in middle of 3-second of the 5-second periods were used. The mean value of three trials was used in the data analysis. For each muscle, independent t-tests were performed to compare for group differences. Results: The muscle activity of UT was significantly greater in ESG group, compared to that of the control group (p<0.05). The muscle activity of MD was significantly smaller in ESG group, compared to that of the control group (p<0.05). Conclusion: These findings showed that low muscle activation of MD as well as SA may contribute to hyperactivity of UT during arm elevation.

• 대한의용생체공학회:의공학회지
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• 제37권4호
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• pp.127-133
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• 2016

This study proposes the feasibility for automatic classification of sleep/wakefulness using nasal pressure in patients with sleep-disordered breathing (SDB). First, SDB events were detected using the methods developed in our previous studies. In epochs for normal breathing, we extracted the features for classifying sleep/wakefulness based on time-domain, frequency-domain and non-linear analysis. And then, we conducted the independent two-sample t-test and calculated Mahalanobis distance (MD) between the two categories. As a results, $SD_{LEN}$ (MD = 0.84, p < 0.01), $P_{HF}$ (MD = 0.81, p < 0.01), $SD_{AMP}$ (MD = 0.76, p = 0.031) and $MEAN_{AMP}$ (MD = 0.75, p = 0.027) were selected as optimal feature. We classified sleep/wakefulness based on support vector machine (SVM). The classification results showed mean of sensitivity (Sen.), specificity (Spc.) and accuracy (Acc.) of 60.5%, 89.0% and 84.8% respectively. This method showed the possibilities to automatically classify sleep/wakefulness only using nasal pressure.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.1542-1543
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• 2007

This paper presents the effect of driving waveform for piezoelectric bend mode inkjet printhead with optimized mechanical design. Experimental and theoretical studies on the applied driving waveform versus jetting characteristics were performed. The inkjet head has been designed to maximize the droplet velocity, minimize voltage response of the actuator and optimize the firing frequency to eject ink droplet. The head design was carried out by using mechanical simulation. The printhead has been fabricated with Si(100) and SOI wafers by MEMS process and silicon direct bonding method. To investigate how performance of the piezoelectric ceramic actuator influences on droplet diameter and droplet velocity, the method of stroboscopy was used. Using the water based ink of viscosity of 11.8 cps and surface tension of 0.025N/m, it is possible to eject stable droplets through 64 nozzles average velocity of 4.05 m/s with standard deviation of 0.06 m/s and average diameter of $29.2\;{\mu}m$ with standard variation of $0.5\;{\mu}m$.

• Animal Bioscience
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• 제35권3호
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• pp.475-483
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• 2022

Objective: Methionine (Met) is involved in methyl group transfer besides protein synthesis. As the availability is limited and cost is high for synthetic Met, reductions in its inclusion in broiler diet may be possible by supplementing the low Met diets with methyl donors (MD) like betaine (Bet), folic acid (FA), vitamin B12 (B12), and biotin (Bio). An experiment was conducted to study the effects of supplementing the MD on performance (average daily gain [ADG], daily feed intake, feed efficiency [FE]), anti-oxidant variables, immune responses and serum protein concentration in broilers fed sub-optimal concentrations of dietary Met. Methods: Maize-soybean meal diet was used as control (CD). Different MD like Bet (0.2%), B12 (0.1 mg), FA (4 mg), or Bio (1.5 mg/kg) were supplemented to basal diet (BD) having no supplemental Met. The BD without MD was kept for comparison. Each diet was fed ad libitum to 10 replicates of 25 chicks in each from 1 to 42 d of age. Results: At the end of experiment, the ADG in MD group was higher than BD and lower than CD. The FE improved with FA or Bet compared to the BD. Breast meat weight was higher in Bet compared to the BD, while it was intermediate between BD and CD in other groups. The lipid peroxidation reduced with Bio, B12, or Bet, while the glutathione peroxidase activity improved with Bio or B12 compared to the BD. Lymphocyte proliferation improved with Bet compared to the BD. The serum protein concentrations increased with FA, Bio, or Bet compared to those fed BD. Conclusion: It can be concluded that the ADG can be improved partially with supplementation of MD while the FE improved with FA or Bet. Some MD also reduced the stress indices and improved immune responses compared to the BD fed broilers.

• 한국인터넷방송통신학회논문지
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• 제15권5호
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• pp.147-154
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• 2015

위성통신망은 방송과 마찬가지로 지구국만 갖추고 있다면 누구나 수신이 가능한 특성을 가져 반드시 보안이 요구되는 내용이 있다면 암호화를 행해 주어야 한다. 본 논문에서는 위성통신망 IPsec VPN에서 전송모드 AH 보안헤더를 추가하여 인증데이터 부분에 인증알고리즘 MD-5와 SHA-256을 적용하여 BER과 Error rate 및 Throughput을 분석하였다. 먼저 일반 IP 패킷을 생성하여 IPsec 전송모드 AH 보안헤더를 추가하여 내부 인증 데이터를 SHA-256 및 MD-5알고리즘을 적용하여 구성하였다. 채널코더는 Rate Compatible Punctured Turbo Codes를 적용하였고, 패킷 재전송 기법은 Hybrid-ARQ Type-II와 Type-III을 사용하였다. 변조방식은 BPSK를 적용하였고, 무선채널은 마르코프 채널 (Rician 80%, Rayleigh 20%와 Rician 90%, Rayleigh 10%)로 위성채널 상태에 따라 인증알고리즘이 에러율과 Throughput에 어떤 영향을 미치는지 분석하였다.

• 전기전자학회논문지
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• 제9권1호
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• pp.31-39
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• 2005

본 논문에서는 생체인식 데이터의 보안성을 향상시키기 위하여 MD5(Message Digest5) 와 RSA(Ron Rivest, Adi Shamir, Len Adleman) 알고리즘 등을 이용한 새로운 생체인식 데이터 전송 모델을 제시함으로써 보다 안전하게 사용자 인증을 수행할 수 있도록 하였다. 즉, 클라이언트를 통해 생체인식 종류 가운데 지문을 입력 하도록 하고, 처리된 지문을 서버로 전송한다. 지문 정보가 전송 될 때, 외부로부터의 불법적인 생체 정보를 가로채는 등의 문 제를 해결하기 위해 MD5 알고리즘을 이용하여 정보를 Digest화하고, 이것을 RSA 방식으로 다시 전송하는 과정을 거치도록 하는 것을 보여주었으며, 암호화 되지 않은 일반 텍스트 데이터와 생체 데이터, 암호화 하여 전송하는 생체 데이터의 전송 속도 및 보안성을 각각 비교 실험 하였다. 이러한 개선된 방법을 통하여 사용자 인증을 수행함으로써 인증 절차를 간소화하고 좀 더 정확하고 안정된 방법으로 여러 분야에 적용될 수 있을 것으로 예상 된다.

• Bulletin of the Korean Chemical Society
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• 제18권5호
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• pp.501-509
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• 1997

In recent papers[Bull. Kor. Chem. Soc. 1996, 17, 735; ibid 1997, 18, 478] we reported results of molecular dynamics (MD) simulations for the thermodynamic, structural, and dynamic properties of liquid normal alkanes, from n-butane to n-heptadecane, using three different models. Two of the three classes of models are collapsed atomic models while the third class is an atomistically detailed model. In the present paper we present results of MD simulations for the corresponding properties of liquid branched-chain alkanes using the same models. The thermodynamic property reflects that the intermolecular interactions become weaker as the shape of the molecule tends to approach that of a sphere and the surface area decreases with branching. Not like observed in the straight-chain alkanes, the structural properties of model Ⅲ from the site-site radial distribution function, the distribution functions of the average end-to-end distance and the root-mean-squared radii of gyration are not much different from those of models Ⅰ and Ⅱ. The branching effect on the self diffusion of liquid alkanes is well predicted from our MD simulation results but not on the viscosity and thermal conductivity.