• Korean Journal of Veterinary Service
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• v.41 no.3
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• pp.191-196
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• 2018

Blood tests have been used to develop treatment plans, such as disease diagnosis, treatment effect, and prognosis determination in livestock. The present study examined changes in the blood count, including RBCs, WBCs, and platelets, before and after grazing among the Korean native cattle grazing from spring to autumn. The study compared the blood count of livestock group (A, n=34) that returned from the rangeland to cowshed every evening and livestock group (B, n=21) that were not returned from the rangeland to cowshed every evening during the grazing period. Hematological parameters such as RBC, hemoglobin, hematocrit, MCV, and WBC, neutrophil, eosinophil, monocyte, and lymphocyte were determined using a blood cell analyzer. Livestock group (A) showed significant differences in the values of RBC, MCV, MCHC, WBC, EOS, and LYM. Livestock group (B) showed significant differences in the values of RBC, Hb, HCT, MCV, MCH, PLT, NEU, and BAS. In particular, the RBC count decreased after grazing when compared with that before grazing. Compared with that before grazing, low RBC count was maintained from the first to fifth month of grazing. The WBC count increased from the fourth month of grazing, whereas the EOS count increased from the second month of grazing. These results suggest that the values of RBC and WBC vary before and after grazing, and also with the grazing period. Furthermore, it is necessary to develop a detailed feeding management based on these values of blood analysis for livestock that are raised continuously in the rangeland.

• Korean Journal of Community Nutrition
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• v.6 no.3
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• pp.495-506
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• 2001

This study was conducted to investigate the nutrient intake, dietary and weight control behaviors and iron deficiency of adolescent girls. The subjects were 216 female middle school students living in urban and rural areas of Inchon. Thin cross- sectional study was conducted by questionnaires and data were analyze by SAS program. Nutrient intakes collected from 3 day-recalls were analyzed by the Computer Aided Nutritional Analysis Program(CAN-pro). The mean height, weight. BMI and obesity index for the subjects were 158.2 cm, 51.1kg, 20.4 and -5.3 % in urban students and 155.9 cm, 49.3 kg 21.1 and -8.2% in rural students, respectively. Easting blood samples were obtained and analyzed for iron nutritional status. The mean obesity index of the urban students was higher than that of the rural students. The proportion of the overweight group was higher in urban students compared to rural students, However, over 10% of both area students belonged to the low weight group, respectively. Most students of both areas skipped breakfast and the main reason was on appetite and lack of time. Urban students were more concerned with body image. The nutrients which showed a lower mean intake as percentile of RDA were Ca, iron, vit A an Vit B$_2$ and most nutrient intakes of urban students were significantly higher compared to those of rural students. These results indicate that nutrient intakes in the female middle school students were considerably lower than the RDA. Also they had undesirable food habits and lower self-satisfaction with their body image, There were significant differences in the mean MCV, TIBC and serum ferritin between urban and rural area subjects. Mean Hb, Hct, MCH, MCHC and TS, bowaver, were not significantly different. Prevalence of iron deficiency greatly varied by indices from urban(11.5%) and rural (8.7%) when judged by Hb to urban(23.1) and rural (23.3%) by serum ferrition. Therefore, proper nutrition education is required for good nutrition desirable food habits, weight control, and guidance for iron deficiency in anemic female of adolescents.

• Journal of Pharmacopuncture
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• v.4 no.3
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• pp.85-92
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• 2001

Objective : This study was purposed to investigate the acute. subacute toxicity of Herbal acupuncture with Juglandis Semen(JsD) in mice and rats. Methods & Results: Balb/c mice were injected intraperitoneally with JsD for $LD_{50}$ and acute toxicity test Sprague-Dawley rats were injected intraperitoneally with JsD for subacute toxicity test. Results: The results obtained were summarized as follows; 1. LD50 was uncountable as could not find the expired of treat group. 2. The clinical signs and body weight changes of mice treated with 0.2cc, 0.4cc JsD were not affected during the acute toxicity test. 3. In acute toxicity test of serum biochemical values of mice, total protein was increased in treat-l group, compared with normal group, and total cholesterol was increased in treat-2 group, compared with normal group.(P<0.05) 4. In subacute toxicity test, main toxic syndrome was not found. 5. The body weight was decreased in treat-2 group, compared with normal group and relative liver weight was decreased in treat-1, 2 group, compared with normal group in subacute toxicity test.(P<0.05) 6. In subacute toxicity test, WBC, MCH, MCHC were decreased in treat-2 group and RBC was increased in treat-2 group, compared with normal group in complete blood count test.(P<0.05) 7. In subacute toxicity test, treat groups were not changed serum biochemical values of rats, compared with normal group.(P<0.05) Conclusions: According to the results, Herbal-acupuncture with Juglandis Semen caused no toxicity.

• Korean Journal of Health Education and Promotion
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• v.10 no.1
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• pp.98-105
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• 1993

최근 경제수준 향상과 소자녀 가치관의 확립, 그리고 전국민 의료보험 실시 등으로 인하여 모자보건 대상자의 대부분은 민간 의료시설의 전문인력으로부터 서비스를 제공받게 되었고, 모자보건 수준도 급격히 향상, 1992년 시설분만율의 경우, 99%에 도달하였다. 이렇듯 의료시설 이용의 증가와 의료기술의 발전에도 불구하고, 영아사망율 및 모성사망율이 최근 몇년동안 같은 수준에 머무르고 있음은, 보다 질적인 관리측면으로 사업의 방향이 전환되어야 함을 의미하는데 이는 곧 공공성을 띠고 있는 모자보건사업을 국가가 관리하여야 할 필요성을 더욱 크게 한다. 공공부문에서는 취약대상을 위하여 민간 전문인력과의 유기적인 연계체계를 마련하여 계속적인 관리를 제공할 수 있도록 하고, 보건교육 강화를 위한 관련 홍보물(모자보건수첩 활용, 모유수유 권장, 제왕절개수술 지양 등)을 제작하며 신경아세포종 검사 등과 같은 새로운 예방사업 개발에 중점을 두어야 할 것이다. 또한 영유아관리는 저체중아 및 장애아에 대한 추구관리서비스까지 확대되어야 할 것이다. 현 우리나라 주산기구급이송체계는 응급의료체계내에서 이루어지고 있다고 볼 수 있는데 주산기관리를 위한 의료여건이 성숙되어 있지 못하고 있는데다(이 시기의 집중관리를 통하여 사망 및 장애아 예방이 가능) 관련 제도마저 취약하여 민간의료부문에서는 영아사망 및 모성사망을 낮추기 위해서는 이 부문에 대한 노력이 집중되어야 할 것이다. 첫째, 주산기학, 신생아학 전문인력의 훈련제도 확립파 주산기 관리시설의 지역적 적정분배(분만 2,000건에 1개 시설마련), 둘째, 집중적인 인력과 고가장비가 투입되는 주산기 의료활동 강화를 위한 관련 의료제도의 수정 및 보완, 세째, 질적관리가 매우 중시되는 고위험 신생아의 집중관리를 위한 '표준 의료관리지침서' 마련, 네째, 동 시설 및 관리에 준하여 주산기 의료시설에 대한 감독 및 감시기능 강화를 위한 제도적 장치가 마련되어야 할 것이다.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.4
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• pp.1163-1168
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• 2004

In order to establish the experimental clinical model for evaluating the influences on the sexual hormones of SD-rat administrated with Methoxychlor(MET), it was dissolved in acetone and olive oil (1:19), which was administrated orally at doses of 200㎎/㎏ body weight/day for 7 days. The Testosterone value was measured in sera by Gamma Count with 1251 isotype, also weights of the body, testis and liver were measured for 15 weeks. Testosterone in the serum of intacted SD-rats was 0.51±0.43ng/㎖(n=5), but it was 0.69±0.18(n=2)ng/㎖l on 1 week. 0.28±0.05ng/㎖(n=2) on 3 week, 1.52±0.95ng/㎖(n=3) on 5 week, and 0.54±1.95 ng/㎖(n=3) 15 week post-dosing MET, respectively. Histologically, the numbers of spermatozoa and Leydig cells were reduced, which might influence to reduce sexual hormone, and AST and ALT was not increased in the serum due to administrating with MET, blood profile was not changed according to the administration of MET excepting MCH(Mean Corpuscular Hemoglobin). This study suggest that change of male sexual hormone by MET be a experimental model for evaluating some drugs associate with sex hormone.

• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.86-94
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• 1999

To invstigate the available dosage and effects of xylazine as preanesthetics on the propofol anesthesia in the dog, the experimental animals were randomly divided into 3 groups (xylazine 0.55 mg/kg (group 1), 1 mg/kg (group 2) and 2 mg/kg (group 3) were premedicated) and, monitored analgesic and anesthetic effect, body temperature, respiratory rate (breaths/minute), heart rate (beats/minutes). Also, hematological and serum chemical changes were monitored. In all experimental groups, the animals were recumbent just after propofol injection and time difference was not detected. Except vomitting after xylazine injection and insignificant ataxia during recovery, no significant side effects were observed. In group 2, loss of toe-web needle prick response time was slightly longer than group 1 but the response in group 2 and group 3 were similar, In group 2 and 3, the duration of anesthesia was longer than group 1 (2 folds) but there was no difference between group 2 and 3. Recovery time was prolonged in proportion to administration dosage of xylazine. In all experimental groups, the body temperature of animals was decresed gradually according to experimental time but no significant changes were monitored. The heart rate and respiratory rate were significantly (p<0.01, p<0.05) decreased after propofol injection Hematologically, no significant changes were monitored in total leukocye numbers, total erythrocye numbers, MCV, MCH, MCHC, serum GOT and GPT values Significant changes in all groups were not observed except significant increase in BUN, total-protein and abumin values of group 3. On the basis of these result, premedication of xylazine can be helpful in decresing some side effects and the dosage of propofol. 1 mg/kg of xylazine as preanesthetics on the propofol anesthesia in the dog is considered to be available.

• Journal of Veterinary Clinics
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• v.28 no.4
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• pp.365-368
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• 2011

Next to performing an expert physical examination, a blood sample submitted for a complete blood count is the most basic tool available to owners or veterinary practitioners. Reference values of complete blood count were determined at 6 different ages in 114 Thoroughbred foals during the second month of life. Hematologic results were as follows: RBC 8.2-10.5 ($10^6/{\mu}l$), Hb 10.9-13.3 (g/dl), HCT 28.2-35.2 (%), MCV 30.7-35.8 (fL), MCH 11.9-13.5 (pg), MCHC 37.9-40.5 (g/dl), RDW 24.5-25.7 (%), PLT 146.3-256.4 ($10^3/{\mu}l$), MPV 6.7-8.3(fL), total WBC 8.1-12.5 ($10^3/{\mu}l$), basophils 0.0 ($10^3/{\mu}l$), eosinophils 0.0-0.3 ($10^3/{\mu}l$), neutrophils 2.4-8.6 ($10^3/{\mu}l$), lymphocytes 1.8-2.9 ($10^3/{\mu}l$) and monocytes 0.0-1.4 ($10^3/{\mu}l$). The results of this study serve as reference ranges for Thoroughbred neonatal foals populations and can be useful for health control, regular examination and pre-sale soundness examination.

• Journal of Veterinary Clinics
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• v.28 no.4
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• pp.357-364
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• 2011

To evaluate hepatoprotective effect of Epimedium Koreanum nakai (EKN) on liver-damaged animal model, rats were intoxicated with carbon tetrachloride (1 ml/kg) for 9 weeks orally. Liver-damaged rats were divided into 2 groups: liver-damaged control (LDC) group and EKN group were administered vehicle (saline), EKN extract per os for 4 weeks respectively. Normal control (NC) group was administered saline as the same process of LDC group. The weights of prostate (absolute), testis (relative), epididymis (relative) and packed cell volume (PCV), mean corpuscular volume (MCV) of EKN group significantly (P < 0.05) increased compared with LDC group. But Mean corpuscular hemoglobin (MCH), mean corpusulcar hemoglobin concentration (MCHC) and aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) were significantly (P < 0.01, P < 0.05) decreased. Fibrotic regions in hepatic parenchyma of EKN group significantly (P < 0.01) decreased compared with LDC group and mean diameters of hepatic lobules significantly (P < 0.01) increased. Percentages of degenerative kidney regions and number of degenerative kidney tubules, number of vasodilated atrophic glomerulus of EKN group was significantly (P < 0.01, P < 0.05) decreased compared with LDC group. Number of atrophic seminiferous tubules and epididymal tubules showing oligospermatozoa of EKN group were significantly (P < 0.01) decreased compared with LDC group. In conclusion, EKN extract has a favorable effect on the $CCl_4$-induced liver damage.

• Korean Journal of Veterinary Service
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• v.33 no.4
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• pp.411-415
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• 2010

The present study was devised to determine the effects of body weight, organ weight, hematological values and biochemical parameters by vitamin E and selenium (Selevit) in the ovariectomized (OVX) rats. The animals were divided into 4 groups. Intact group (n=10) received no treatment and operation. Sham group (n=10) received only sham operation and no treatment. OVX group received operation and no treatment. OVX+Selevit received operation and Selevit. The body weights of the all group increased, and that of OVX+Selevit group was the lowest rates. There were significant differences (P<0.01, P<0.001) of body weights between OVX+Selevit group and all other groups. Also, organ weights such as heart, liver, spleen and kidney were measured. The heart and liver weight were significantly lower (P<0.01, P<0.001) in the OVX+Selevit group than in the Intact and Sham group. Also, the kidney weight was significantly lower (P<0.05, P<0.01) in the OVX+Selevit group than in the all other group. On the other hand, there was no significantly difference in the organ weight of spleen between the OVX+Selevit group and the other groups. The number of WBC was significantly higher (P<0.05) in the OVX+Selevit group than in the all other groups. The hematological values of RBC, MCV, MCH and MCHC were no significant differences in any groups. The biochemical parameters of serum total protein and alkaline phosphatase increased significantly in the OVX+Selevit group as compared to that in the OVX group. But, there were no significant differences in AST and ALT in any groups. We conclude that vitamin E and selenium were significantly decreased the body weights in the ovariectomized rats. Our findings suggest that vitamin E and selenium may influence the process of lipid packaging and absorption in the ovariectomized rats.

• Korean Journal of Veterinary Service
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• v.33 no.4
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• pp.417-421
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• 2010

The aim of this study was to determine the changes of body weight, organ weight, hematological values and biochemical parameters by testosterone (Testos) on the orchidectomized (Orch) rats. The animals were divided into 4 groups. Intact group (n=10) received no treatment and operation. Sham group (n=10) received only sham operation and no treatment. Orch group received operation and no treatment. Orch+Testos received operation and testosterone. The body weights of each group increased, but that of Orch+Testos group was significantly lower in Orch+Testos group than in all the other groups. There were significant differences (P<0.05, P<0.001) of body weights between Orch+Testos group and all the other groups. Also, organ weights such as heart, liver, spleen and kidney were measured. The heart weights were significantly lower (P<0.001) in the Orch+Testos group than in all the other groups. The liver weights in the Orch+Testos group were significantly differences in comparison with those in the Sham (P<0.001) and Orch group (P<0.05). On the other hand, there were no significantly differences in the organ weights of spleen and kidney between the Orch+Testos group and the any other groups. The hematological values of white blood cell (WBC), red blood cell (RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were no significant differences in any other groups. The concentrations of serum total protein and albumin increased significantly (P<0.05) in the Orch+Testos group as compared to that in the Orch group. However, there were no significant differences in Ca, IP and Mg in any other groups. We conclude that testosterone was significantly decreased the body weight in the orchidectomized rats. Our findings suggest that testosterone may influence the process of lipid packaging and absorption in the orchidectomized rats.