• Neonatal Medicine
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• 제15권1호
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• pp.67-74
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• 2008

목 적 : 융모막의 종류에 따른 주산기에 미치는 영향과 쌍태아간 수혈 증후군이나 선택적 태아 발육부전이 있는 단일 융모막의 주산기 영향을 평가하였다. 방 법 : 2002년 1월부터 2007년 12월까지 일신기독병원에서 재태 연령 12주에서부터 분만과정까지 산전 진찰을 받고 분만을 한 단일 융모막 산모 99명, 이 융모막 산모 206명, 그리고 이들에게서 태어난 188명의 단일 융모막 쌍생아와 411명의 이 융모막 쌍생아를 대상으로 외래 및 입원 병력 기록지를 후향적으로 조사하였다. 쌍태아간 수혈 증후군과 선택적 태아 발육부전의 빈도 및 융모막 종류에 따른 주산기 영향 및 신생아 이환을 평가하였다. 결 과 : 단일 융모막군은 이 융모막군보다 재태 연령이 작고(35.7 vs 36.6, P=0.03) 태아 사망이 많았다(10% vs 1.5%, P<0.001). 그리고 단일 융모막군의 선택적 발육부전이 이 융모막의 선택적 발육부전보다 태아 사망이 높았다(19% vs 2.5%, P=0.025). 신생아 집중 치료실에 입원한 쌍생아는 단일 융모막 쌍생아가 이 융모막 쌍생아보다(31% vs 16%, P=0.042) 빈도가 높았다. 그리고 단일 융모막 쌍생아가 뇌실 주변 백색 연화증(7% vs 0%; P=0.031), Surfactant를 투여한 신생아호흡곤란 증후군(27% vs 11%; P=0.049)의 빈도가 높았다. 단일 융모막군에서 선택적 자궁 내 발육지연의 빈도는 21%였고 태아 간 수혈 증후군의 빈도는 9%이었다. 일측성 태아 사망은 쌍태아간 수혈 증후군에서는 9명중 6명(67%)이고 선택적 태아 발육부전군에서는 21명중에 4명(19%)으로 단순 단일 융모막군보다 유의하게 높았다(P<0.001). 신생아실에 입원한 빈도는 쌍태아 간 수혈증후군에서 92%, 선택적 태 아발육부전에서 42%로 단순 단일 융모막군의 22%보다 유의하게 높았으며(P=0.001) 입원기간 또한 유의하게 길었다(P=0.033). 그리고 뇌실 주변 백색 연화증 및 뇌실 내 출혈빈도인 경우에도 쌍태아간 수혈 증후군과 선택적 태아 발육부전군이 단순 단일 융모막군보다 유의하게 많았다(각각 P=0.011, P=0.007). 결 론 : 쌍태아 간 수혈 증후군이나 선택적 태아 발육부전이 있는 단일 융모막 쌍생아에서 신생아의 합병증이 높다.

• Journal of Periodontal and Implant Science
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• 제30권2호
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• pp.347-360
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• 2000

Bone remodeling results from the combined process of bone resorption and new bone formation which is regulated in part by some of the polypeptide growth factors such as platelet derived growth factor(PDGF), which has been known to be an important local regulator of bone cell activity and participate in normal bone remodeling. This process includes strictly regulated gene expression of several bone matrix proteins such as type I collagen and osteopontin, a 44 kDa phosphorylated glycoprotein, which has important roles in bone formation. The purpose of this study is to evaluate the effecs of PDGF-BB on the mRNA expression of bone matrix protein, type I collagen and osteopontin, in MC3T3- E1 cell culture. Cells were seeded at $5{\times}10^5$ cells in 10 ml of minimum essential medium alpha(${\alpha}-MEM$) containig 10% fetal bovine serum, 10 mM beta glycerophosphate. 0.1, 1, 10 ng/ml PDGF-BB were added to the cells for the day 3, 7, 14, 21, 28 and cultured for 24 hours. Type I collagen cDNA, Hf677, and osteopontin cDNA were used as probes for northern blot analysis. Total cellular RNA was purified at indicated day and northern blot analysis was performed. The results were as follows : Type I collagen mRNA expressions were higher at the day 3 and 7, and lower in the day 14, 21 in the control groups. In the experimental groups, mRNA expressions were increased when 0.1 ng/ml PDGF-BB were added on the day 3, 7, 21, and decreased in dose-dependent manner on the day 14, decreased at all added dose on the day 28. Osteopontin mRNA expressions were highest in the day 21 groups and lowest in the day 14 groups in the control groups. Interesting results were shown in the day 14 and 21 groups. We found that osteopontin mRNA level was increased in dose dependent manner in the day 14 groups, and decreased dose dependent manner in the day 21 groups. In conclusion, PDGF-BB may have various control effects on type I mRNA expression in the growth and differentiation process of MC3T3-E1 cells and may have contrary regulatory effects on osteopontin mRNA expression. For examples, when the baseline level of osteopontin mRNA was low, as in the day 14, PDGF-BB up-regulated osteopontin mRNA expression in dose dependent manner, and when the baseline level was high as in the day 21, PDGF-BB down-regulated dose dependent manner. Thus, it may be useful for clinical application in periodontal regeneration procedure if further study were performed.

• 대한정형도수물리치료학회지
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• 제22권1호
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• pp.65-70
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• 2016

Background: To determine the correlation Between forward head posture and plantar pressor in a McKenzie Exercise. Methods: This study had a cross-sectional design. There are included 20 participants with forward head posture. We measured the craniovertebral angle (CVA), cranial rotation angle (CRA) by image obtained digital camera and the plantar pressure, static balance using Gait Analyzer each before and after McKenzie Exercise. Results: There was negative correlation between CVA and CRA (p<.05). There was negative correlation between CVA and fore foot(p<.05). There was positive correlation between CRA and both fore foot (p<.05). There was negative correlation between CVA and static balance(p<.05). There was positive correlation between CRA and static balance (p<.05). Conclusions: There is a correlation between the change a mount of forward head position and plantar pressure in the McKenzie Exercise.

• 한국연초학회지
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• 제11권2호
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• pp.241-246
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• 1989

Mold development on leaf tobacco(Flue-cured, var. NC 82) during the storage was examined according to the initial moisture content(MC) of the tobacco. The initial moisture content of the leaf tobacco was controlled as 12,14,16% after redrying. Those were packed in cardboard boxes and stored in a warehouse. Samples were taken monthly from June of 1988 through August of 1989 and were evaluated for mold development (colony count) and MC. The moisture content change in the leaf tobacco of 12, 14 and 16% initial MC was in the range of 11.1-13.3, 12.8-15.3 and 14.9-16.7% and the mean number of colonies from them were 1.4$\times$102, 1.0$\times$102, and 4.0$\times$102 colonies per gram of tobacco, respectively, however mold-damaged leaf tobacco other than the treatments was occasionally observed to have the colony number as high as 2.3$\times$105 colonies per gram of tobacco. In the meantime, the leaf tobacco was stored at 6 relative humidity levels at $25^{\circ}C$ in laboratory test. Leaf tobacco of 15.0-16.4% MC was maintained without the mold-damage after 80 days of storage whereas those of 19.9, 21.3, 25.5 and 27.1% MC became moldy after 50, 15, 11 and 6 days of storage, respectively.

• Archives of Pharmacal Research
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• 제21권5호
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• pp.496-502
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• 1998

The present study was carried out to determine the possible use of cTn-I in the cardiac myofibrillar architecture, as a potential target for in vivo radioimmunodetection of cardiac damage in a brain death pig model. Radioiodiantion of the anti-cTn-I 5F4 McAb was carried out by lactoperoxidase method. the percentage iodine incorporation achieved was 70-75%. The radioiodinated McAbs were purified on Sephadex G-25 column and characterised by Paper chromatography, Phast Gel electrophoresis and electroimmunoblotting. Radioiodinated anticTn-I 5F4 McAbs were employed alongside Pyrophosphate($Tc_{99m}$-PPi$) and $Thallium^{201}$ chloride($TI^{201}$) in 24 landrace pigs (brain-dead=18 & sham-operated=6). The percentage cardiac uptake of the radiolabelled antibody injected dose was significantly higher in the brain dead animals(0.196%) as compared to that of sham-operated animals (0.11%). Specific in vivo localization of radiolabelled McAbs in the infarcted cardiac tissue was confirmed by computer-aided reconstruction of 3-D images of the isolated heart. The preliminary results of the study revealed preferential uptake of radiolabelled antibody at the site of myocyte damage resulting from artificially induced brain death.

• Animal Systematics, Evolution and Diversity
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• nspc3호
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• pp.45-58
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• 1992

Tetranychoid mites found from Korea until now are 42 species belonging to 12 genera, 2 families as follows: 1 Bryobia japonica Ehara et Yamada, 2. B. praetiosa Koch, 3. B. rubrioculus(Scheuten), 4. Petrobia latens(Muller), 5. Aponychus corpuzae Rimando, 6. A firmianae(Ma et Yuan). 7. Panonychus citri(McGregor), 8. P. ulmi(Koch), 9. Eotetranychus carpini Oudemans, 10. E. hicoriae(McGregor), 11. E. populi(Koch), 12. E. rubiphilus (Reck), 13. E. sexmaculatus (Riley), 14. E. smithi Pritchard et Baker, 15. E. tiliarium (Hermann), 16. E. uchidai Ehara, 17. Schizotetranychus bambusae Reck, 18. S. celarius(Banks), 19. S. leguminosus Ehara, 20. Oligonychus aceris(Shimer), 21. O. clavatus(Ehara), 22. O. hondoensis(Ehara), 23. O. ilicis(McGregor), 24. O. karamatus(Ehara), 25. O. orthius Rimando, 26. O. peridtus Pritchard et Baker, 27. O. shinkajii Ehara, 28. O. pustulosus (Ehara), 29. O. ununguis(Jacobi), 30. O. sp. 31. Tetranychus kanzawai Kishida, 32. T. phaselus Ehara, 33. T. truncatus Ehara, 34. T. urticae Koch, 35. T. vienensis Zacher, 36. Aegyptobia nothus Pritchard et Baker, 37. Pentamerismus taxi (Haller), 38. P. oregonensis McGregor, 39. Brevipalpus californicus(Banks), 40. B. lewisi McGregor, 41. B. obovatus Donnadieu, 42. Tenuipalpus zhizhilashviliae Reck. On the above species, a taxanomic key was made and ecological data including distribution and host plant are presented in this paper.

• 복식문화연구
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• 제13권2호
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• pp.300-313
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• 2005

Hybrid trend of the 21st century is an important basis to express fashion Alexander McQueen is a representative designer of Hybrid trend which combines heterogeneous elements into oneconcept. Accordingly, this study distributed and analyzed Hybrid trend which was in Alexander McQueen's work like below. First, there was a racial Hybrid trend which combined different local culture in shared space of the world in his fashion work and he challenged to Westernized ideal beauty with new recognition and knowledge about beside countries of Western Europe which were considered as not important culture due to perceiving relative value of a pluralist society and created new way aesthetic consciousness. Second, he expressed a historical character of a combination of tradition and modern by his fashion work based on wide historical knowledge of a dress. He created a new line in contrast to the past with a perfect design through combination of the style from the tradition with the parody and displayed his own design world. Third, he treated instability and disorder from the interior essential dissolution, thus he had a cultural character which broke down the boundary of cultural genre and style. This attitude showed transformation of constructivism and deconstruction view, secession and distortion, mixture, duplication, secession and insert by his fashion work.

• 대한간호학회:학술대회논문집
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• 한국간호과학회 2005년도 The 5th International Nursing Conference
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• pp.17-21
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• 2005

• Journal of Dental Anesthesia and Pain Medicine
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• 제21권2호
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• pp.179-181
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• 2021

• Journal of Periodontal and Implant Science
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• 제31권2호
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• pp.287-298
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• 2001

Recently, many natural medicines, which have advantage of less side effects and possibility of long-term use have been studied for their capacity of anti-bacterial, anti-inflammatory and regenerative potential of periodontal tissues. Olibanum has the effects to hemostasis, analgesic and anti-inflammatory, and it also has been traditionally used as a drug for the treatment of bone disease in oriental medicine. The purpose of the present study was to investigate the effects of Olibanum extracts on the activity and differentiation of MC3T3-E1 cells, alkaline phosphatase(ALP) synthesis, formation of bone nodules and expression of type I collagen of MC3T3-E1 cells. To examine the cellular activity, MC3T3-E1 cells were cultured with ${\alpha}-MEM(control)$ and each concentration of Olibanum for 2 days and 4 days. To compare the ALP synthesis, MC3T3-E1 cells were cultured with ${\alpha}-MEM(negative\; control)$, dexamethasone(positive control), and each concentration of Olibanum for 2 days and 4 days. To compare the bone nodule formation, MC3T3-E1 ells were cultured for 21 days, and to compare the type I collagen expression, MC3T3-E1 cells were cultured for 4 days. The cellular activity of MC3T3-E1 cells treated with $1{\mu}g/ml$ of Olibanum extracts was significantly increased at 4-day(p<0.05) to control. The activity of ALP in MC3T3-E1 cells treated with $1{\mu}g/ml$ Olibanum extracts was significantly increased at 4-day(p<0.05). All the experimental groups showed much more bone nodule formation than control groups. The group treated with $1{\mu}g/ml$ of Olibanum extracts was the highest bone nodule formation, and showed much more type I collagen expression than negative control. These results indicate that Olibanum extracts may be considered effective in the activity and differentiation of MC3T3-E1 cells.