• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.9
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• pp.1605-1614
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• 2008

This paper proposed a new VLSI architecture of motion estimation (ME) and compensation (MC) for efficient video compression and implemented it to hardware. ME is generally calculated using SAD result. So we proposed a new arithmetic method for SAD. The proposed SAD calculation method increases arithmetic efficiency and decreases external memory usage. Finally it increases performance of ME/MC. The proposed ME/MC hardware was implemented to ASIC with TSMC 90nm HVT CMOS library. The implemented hardware occupies about 330K gates and stably operates the clock frequency of 143MHz.

• Archives of Orthopedic and Sports Physical Therapy
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• v.14 no.2
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• pp.109-115
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• 2018

Purpose: McKenzie is a widely-used and conventional clinical therapeutic exercise for patients with mechanical lower back pain. It is a well-designed assessment and classification system for the spine. Main issue: Patients with mechanical lower back pain are classified into one of three mechanical syndromes (posture, dysfunction, or derangement syndrome) by mechanical loading strategies. These methods evaluate symptomatic and mechanical responses during repeated end-range movement and sustained postures. The goal of McKenzie mechanical syndrome diagnosis is to determine directional preferences. Directional preference is a phenomenon of preference for posture or movement in one direction, which reduces or centralizes pain. However, in Korea, there is a lack of awareness of basic McKenzie mechanical syndromes diagnostic concepts. Koreans tend to think of the McKenzie method as a simple lumbar extension exercise. However, an accurate diagnosis of a mechanical syndrome must precede the application of McKenzie exercise. Conclusions: Thus, in this study, I present a classification method of McKenzie mechanical syndrome diagnosis and clinical characteristics of each mechanical syndrome.

• Archives of Orthopedic and Sports Physical Therapy
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• v.14 no.2
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• pp.91-97
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• 2018

Purpose: The purpose of this study was to observe the effects of sport massage and McKenzie stretch exercise on forward head posture. To understand the effect, this study measured and analyzed body alignment of the neck. Methods: In this study, a total of 14 subjects with forward head posture were analyzed. Subjects were divided into two groups: group 1 (n=7) received a McKenzie stretch exercise and group 2 (n=7) received a McKenzie stretch exercise and a sport massage. The McKenzie stretch exercise was performed three times a week, for four weeks, while the sport massage was performed once a week. The body alignment of the neck (CVA, CRA) was measured using a goniometer. Results: The improvements in neck body alignments (CVA, CRA) after the McKenzie stretch exercise and sport massage were both significant (group 1: p<0.05; group 2: p<0.05), whereas the between-group comparison found no significant differences. Conclusions: In conclusion, our study confirmed that the McKenzie stretch exercise and sport massage had a significant positive effect on the body alignment of the neck. However, a study that included a greater number of subjects and a long-term treatment period is needed to generalize these results.

• Nuclear Engineering and Technology
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• v.54 no.10
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• pp.3803-3810
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• 2022

OpenMC is a community-driven open-source Monte Carlo neutron and photon transport simulation code. The Weight Window Mesh (WWM) function and an automatic Global Variance Reduction (GVR) method was recently developed and implemented in a developmental branch of OpenMC. This WWM function and GVR method broaden OpenMC's usage in general purposes deep penetration shielding calculations. However, the Local Variance Reduction (LVR) method, which suits the source-detector problem, is still missing in OpenMC. In this work, the Weight Window Generator (WWG) function has been developed and benchmarked for the same branch. This WWG function allows OpenMC to generate the WWM for the source-detector problem on its own. Single-material cases with varying shielding and sources were used to benchmark the WWG function and investigate how to set up the particle histories utilized in WWG-run and WWM-run. Results show that there is a maximum improvement of WWM generated by WWG. Based on the above results, instructions on determining the particle histories utilized in WWG-run and WWM-run for optimal computation efficiency are given and tested with a few multi-material cases. These benchmarks demonstrate the ability of the OpenMC WWG function and the above instructions for the source-detector problem. This developmental branch will be released and merged into the main distribution in the future.

• Korean Journal of Agricultural Science
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• v.51 no.1
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• pp.53-61
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• 2024

A total of 180 21-day-old weaning pigs ([Yorkshire × Landrace] × Duroc) with an initial body weight of 6.44 ± 0.01 kg were randomly assigned to 9 treatments for evaluating the effects of replacing dietary inorganic copper (Cu) and zinc (Zn) with glycine (Gly) or methionine (Met)-chelated Cu and Zn on growth performance and nutrient digestibility. The experimental period was 35 days. There were four replicated pens per treatment, with five pigs (three males and two females) per pen. Dietary treatments consisted of a basal diet (CON), in which the sources of Cu and Zn were in inorganic form. The inorganic Cu and Zn in the basal diet were replaced by glycine-chelated (GC) and methionine-chelated (MC) Cu and Zn by 30, 50, 70, or 100% to form the GC1, GC2, GC3, GC4, or MC1, MC2, MC3, MC4 groups. The 100% replacement of dietary inorganic Cu and Zn with GC or MC increased (p < 0.05) average daily gain, average daily feed intake, and gain-to-feed ratio. The complete replacement of dietary inorganic Cu and Zn with GC or MC led to enhanced (p < 0.05) digestibility of dry matter, nitrogen, Cu and Zn. Thus, the replacement of inorganic Cu and Zn with GC or MC can improve the growth efficiency and nutrient utilization of weaning pigs.

• Journal of Acupuncture Research
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• v.25 no.2
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• pp.41-57
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• 2008

목적 : 이 연구는 Vipera lebetina turanica의 사독약침액(蛇毒藥鍼液)(Snake venom toxin, SVT)이 인간 신경아세포종의 암세포주인 SK-N-MC 세포에서 암세포성장의 억제 및 그 기전에 대하여 살펴보고자 하였다. 방법 : SVT를 처리한 후 SK-N-MC의 성장억제를 관찰하기 위해 CCK-8 assay와 LDH assay를 시행하였고, apoptosis 평가에는 세포형태의 관찰과 DAPI, TUNEL, Annexin V-PI double staining assay 및 cell detachment assay를 시행하였다. 세포자멸사 관련 세포기전을 보기 위하여 세포주기, 세포내 칼슘량, 세포내 활성산소량 및 미토콘드리아의 세포막전위 변화를 측정하였고, DNA fragmentation assay를 시행하였으며, 세포자멸사 조절 단백인 Bax, Bcl-2, caspase-3, -9의 발현 변화 관찰에는 western blot analysis를 시행하였다. 결과 : SK-N-MC 세포에 SVT를 처리한 후, 신경아세포종 세포의 성장, Apoptosis의 유발 및 기전에 영향을 관찰하여 다음과 같은 결과를 얻었다. 1. SVT를 처리한 SK-N-MC 세포 관찰에서 $20{\mu}g/m{\ell}$ SVT 처리가 암세포성장의 유의한 억제를 나타내었다. 세포독성 관찰에서 SVT처리는 처리하지 않은 것에 비하여 증가를 나타내었다. 2. 세포자멸사 평가에서 SVT를 처리한 SK-N-MC 세포는 세포자멸사의 특징적 형태를 나타내었다. TUNEL assay에서는 세포자멸사 활성세포가 미약하게 나타난 반면 cell detachment assay와 Annexin V-PI double staining에서는 각각 세포박리와 세포자멸사 활성세포의 유의한 증가를 나타내었다. 3. 세포자멸사 관련 세포기전연구에서 SVT를 처리한 SK-N-MC 세포의 세포주기, 세포내 칼슘량 및 DNA fragmentation에는 유의한 변화가 관찰되지 않은 반면 세포내 활성산소 양은 유의한 증가를 나타내었고, 그에 따른 미토콘드리아 세포막 전위의 유의한 변동이 관찰되었다. 4. SVT를 처리한 SK-N-MC는 세포자멸사 관련 단백 발현에서 caspase-9에 대해 유의한 증가를 나타내지 않았으나 Bax 및 caspase-3의 유의한 증가와 Bcl-2의 유의한 감소를 나타내었다. 결론 : 이상의 결과는 SVT가 세포내 활성산소를 증가시키므로 미토콘드리아의 세포막전위에 변화를 일으켜 인간 신경아세포종 세포주인 SK-N-MC의 세포박리와 유관한 세포자멸사를 유발하므로 증식억제 효과가 있음을 입증한 것이다.

• Environmental Mutagens and Carcinogens
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• v.24 no.1
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• pp.40-45
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• 2004

In order to understand the mechanism of the regulation of drug metabolizing enzyme gene expression, we have studied the induction of CYP1A1 and GSTα, μ, π enzymes in Japanese monkey and rhesus monkey after the treatment with 3-methylcholanthrene (3MC) and di-n- butyl phthalate (DBP) and bisphenol A (BPA). The levels of mRNA were measured_by RT-PCR in brain, intestine and liver. In the case of adult monkey, treatment with 3MC induced CYP1A1 mRNA in brain by 2-fold. The treatment with DBP induced CYP1A1 mRNA. Effects of 3MC and DBP on GST mRNA expression was not clear. But GSTμ was slightly inhibited by the treatment with 3MC and DBP. GSTα was not induced by the treatment with 3MC and DBP in brain. GSTπ was slightly induced by the treatment with 3MC and DBP in brain. In the case of fetus monkey, the basal levels of fetus CYP1A1 mRNA and GSTs mRNA were relatively low compared to adult monkey. As the age of monkey increased, the basal levels of CYP1A1 mRNA were also increased. 3MC induced the expression of CYP1A1 mRNA in liver, whereas it didn't significantly induce CYP1A1 mRNA in brain. The levels of GSTμ and GSTα were not changed by the treatment with 3MC and DBP. GSTπ was slightly induced by the treatment with 3MC and DBP.

• Environmental Mutagens and Carcinogens
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• v.24 no.2
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• pp.73-78
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• 2004

In order to understand the mechanism of the regulation of drug metabolizing enzyme gene expression, we have studied the induction of CYP1A1 and GST$\alpha$, $\mu$, $\pi$ enzymes in Japanese monkey and rhesus monkey after the treatment with 3-methylcholanthrene (3MC) and di-n- butyl phthalate (DBP) and bisphenol A (BPA). The levels of mRNA were measured by RT-PCR in brain, intestine and liver. In the case of adult monkey, treatment with 3MC induced CYP1A1 mRNA in liver by 10-fold. The treatment with DBP induced CYP1A1 mRNA. Effects of 3MC and DBP on GST mRNA expression was not clear. But GST$\mu$ was slightly inhibited by the treatment with 3MC and DBP. GST$\pi$ was not induced by the treatment with 3MC and DBP in liver. GST$\alpha$ was slightly induced by the treatment with 3MC and DBP in liver. In the case of fetus monkey, the basal levels of fetus CYP1A1 mRNA and GSTs mRNA were relatively low compared to adult monkey. As the age of monkey increased, the basal levels of CYP1A1 mRNA were also increased. 3MC induced the expression of CYP1A1 mRNA in liver. The levels of GST$\mu$ and GST$\alpha$ were not changed by the treatment with 3MC and DBP. GST$\pi$ was slightly induced by the treatment with 3MC and DBP.

• Journal of Satellite, Information and Communications
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• v.3 no.1
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• pp.8-14
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• 2008

In this paper, we analyze throughput performance of MF-TDMA scheme and QS MC-DS/CDMA(quasi-synchronous MC-DS/CDMA) scheme based on scrambling on WH sequence and PPGC sequence in early frequency offset caused by high speed transfer terminal. QS MC-DS/CDMA scheme with scrambled WH sequence shows 5.7% higher throughput than MF-TDMA scheme and 8% higher throughput than QS MC-DS/CDMA with PPGC sequence in high speed transfer terminal environment such as maximum 1000Km/h speed with high frequency of Ka-band. Finally, we show that QS MC-DS/CDMA scheme with scrambled WH sequence is more efficient than traditional MF-TDMA scheme at the aspect of throughput in DVB-RCS system with Ka frequency band.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.12C
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• pp.1135-1142
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• 2006

This article presents a new asynchronous MC-CDMA system to implement multiple data rate communications. In a W-CDMA downlink, the OVSF code is used for spreading code for various multimedia traffic. Proposed system utilizes the OVSF code that generated by generation property for spreading. The proposed MC-CDMA system use different lengths of OVSF code as a spreading code according to their data rate. The groupwise processing is accomplished by code grouping in OVSF code generation tree. Between each group, the code grouping interference canceller is performed to cancel other group interference. At that time the proposed receiver does not require any information about interference users. For the analysis of average BER performance, we propose system model and computer simulation were used. We also compare the system performance with that of a single rate MC-CDMA system used orthogonal code as a spreading code.