• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.569-572
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• 2004

Marchiafava-Bignami Disease(MBD) is a rate disease caused by chronic alcohol abuse and involves the degeneration of corpus callosum pathological in character. Until recently there was no method to diagnose MBD except postmortem examination, but nowadays rodiology has advanced increasingly, so MBD can be diagnosed correftly and easily. A case of MBD with stroke symptoms is reported. A 56-year-old man who has been a heavy alcoholic for several years was admitted with stroke symptoms such as stuporous mental, hemi-extremities weakness, dysphasia and dysphagia. After treatment these symptoms were improved.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.2
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• pp.338-343
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• 2004

In Block Matching Algorithm (BMA), a search pattern has a very important affect on the search time and the output quality. In this paper, we propose the HDS( Half Diamond Search) pattern based on the cross center-biased distribution property of a motion vector. At lust, the 4 points in the above, below, left, and right around the search center is calculated to decide the point of the MBD (Minimum Block Distortion). And an above point of the MBD is checked to calculate the SAD. If the SAD is less than the previous MBD, this process is repeated. Otherwise, the left and right points of MBD are calculated to decide the points that have the MBD between two points. These processes are repeated to the predicted direction for motion estimation. Experiments show that the speedup improvement of the proposed algorithm can be up to 23% while maintaining similar image quality.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.05a
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• pp.839-845
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• 2003

This paper introduces multichannel blind source separation (BSS) and multichannel blind deconvolution (MBD) based on higher order statistics of signals from convolutive mixtures. In particular, we are concerned with the case that the number of inputs is the same as the number of outputs. Simulations for two input two output cases are carried out and their performances are assessed. One of the major applications of those sequential algorithms (BSS and MBD) is demonstrated through the fault signal detection from only a single measurement of rotating machine, which offers a certain degree of practicability in the engineering field such as machine health monitoring or condition monitoring.

• Childhood Kidney Diseases
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• v.24 no.1
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• pp.14-18
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• 2020

Chronic kidney disease-mineral bone disorder (CKD-MBD) is a systemic disorder of mineral and bone metabolism caused by CKD. Patients with early-stage CKD who present with disordered regulation of bone and mineral metabolism may be asymptomatic. However, if untreated, the condition can be a significant barrier in achieving optimal bone strength, linear growth, and cardiovascular health in pediatric patients with CKD. Thus, the current study evaluated the definition, pathogenesis, diagnosis, and management of pediatric CKD-MBD.

• CDE review
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• v.23 no.1
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• pp.22-25
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• 2017

• Archives of Plastic Surgery
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• v.41 no.3
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• pp.258-263
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• 2014

Background For early breast cancer patients, skin-sparing mastectomy or nipple-sparing mastectomy with sentinel lymph node biopsy has become the mainstream treatment for immediate breast reconstruction in possible cases. However, a few cases of skin necrosis caused by methylene blue dye (MBD) used for sentinel lymph node localization have been reported. Methods Immediate breast reconstruction using a silicone implant was performed on 35 breasts of 34 patients after mastectomy. For sentinel lymph node localization, 1% MBD (3 mL) was injected into the subareolar area. The operation site was inspected in the postoperative evaluation. Results Six cases of immediate breast reconstruction using implants were complicated by methylene blue dye. One case of local infection was improved by conservative treatment. In two cases, partial necrosis and wound dehiscence of the incision areas were observed; thus, debridement and closure were performed. Of the three cases of wide skin necrosis, two cases underwent removal of the dead tissue and implants, followed by primary closure. In the other case, the breast implant was salvaged using latissimus dorsi musculocutaneous flap reconstruction. Conclusions The complications were caused by MBD toxicity, which aggravated blood disturbance and skin tension after implant insertion. When planning immediate breast reconstruction using silicone implants, complications of MBD should be discussed in detail prior to surgery, and appropriate management in the event of complications is required.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.4
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• pp.465-474
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• 2012

In this study, a dynamic simulation model that considers many spherical particles and multibody dynamics (MBD) entities is developed. Plenteous spherical particles are solved using the Discrete Element Method (DEM) technique and simulated on a GPU board in a PC. A fast algorithm is used to calculate the Hertzian contact forces between many spherical particles, and NVIDIA CUDA is used to increase the calculation speed. The explicit integration method is applied to solve the many spheres. MBD entities are simulated by recursive formulation. Constraints are reduced by recursive formulation, and the implicit generalized alpha method is applied to solve the dynamic model. A new algorithm is developed to simulate the DEM and MBD models simultaneously. As a numerical example, a truck car model and gear model are developed. The results show that the proposed algorithm using a general-purpose GPU in a PC has many advantages.

• Childhood Kidney Diseases
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• v.18 no.2
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• pp.64-70
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• 2014

Purpose: The aims of this study were to assess the clinical and laboratory profiles of chronic kidney disease-mineral bone disorder (CKD-MBD) and to assess the effects of treatment of active vitamin D analogs on severe hyperparathyroidism (SHPT) in pediatric patients on chronic peritoneal dialysis. Methods: This is a retrospective study included 53 patients who had been undergoing dialysis for more than 1 year, between January 2003 and December 2012. Results: Even after treatment with phosphate binders and active vitamin D analogs, the $mean{\pm}standard$ deviation of the percentage of time during peritoneal dialysis that the patients' serum concentrations of phosphorus, corrected total calcium, and parathyroid hormone (PTH) fell within the Kidney Disease Outcomes Quality Initiative recommended ranges was $25.06{\pm}17.47%$, $53.30{\pm}23.03%$, and $11.52{\pm}9.51%$, respectively. Clinical symptoms or radiological signs of CKD-MBD were observed in 10 patients (18.9%). There were significant differences in percentage of time that the serum intact PTH concentration was outside of the recommended range between patients with and without symptoms or signs of CKD-MBD (below recommended range, $11.74{\pm}7.37%$ vs. $40.77{\pm}25.39%$, P <0.001; above the recommended range, $63.79{\pm}27.86%$ vs. $37.09{\pm}27.76%$, P =0.022). Of the 25 patients with SHPT, high-dose alfacalcidol treatment was required in 13 patients that controlled SHPT in 7 of these patients, without marked complications. Conclusion: Despite our efforts to manage CKD-MBD, patients' met the recommended ranges from relevant guidelines at a low frequency. The treatment of high-dose active vitamin D analogs was required in about half of the patients with SHPT and effective in about half of them.

• Transactions of the Korean Society of Automotive Engineers
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• v.25 no.1
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• pp.116-126
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• 2017

We suggest a process for the basic software configurations and application development in the mode management design of AUTOSAR-based ECU. Mode management is an essential task and AUTOSAR provides the mode management components for the runtime state handling of an ECU, such as BswM, application mode manager and RTE. BswM is used to meet the custom's requirements for ECU state handling. The behavior of BswM is configured with a set of rules in the form of "if-else" statements, so it is a complicated job and a potential source of errors as the number of rules increases. These difficulties can be overcome using the Model-Based Development approach, which is widely used in the AUTOSAR SW development. An efficient process is proposed to apply the MBD approach to the BswM configuration. An application mode development process is also proposed to improve the mode management design by combining the MBD process. Development tools are developed to adapt these proposed processes to the traditional ones. Simulation and experimental results are provided to prove the feasibility of the proposed approach.

• Nuclear Engineering and Technology
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• v.55 no.11
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• pp.4125-4133
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• 2023

The transportation of spent nuclear fuel is an important process that involves road and sea transport from an interim storage facility to storage and final disposal sites. As spent nuclear fuel poses a significant risk, carefully evaluating its vibration and shock characteristics under normal transport conditions is essential. In this regard, full-scale multi-modal transport tests (MMTT) have been conducted domestically and internationally. In this paper, we discuss the process of developing a multi-body dynamics (MBD) model to analytically simulate conditions that cannot be considered in tests. The MBD model is based on the KORAD-21 transportation system was validated using the Korean MMTT results from 2020 to 2021. This paper summarizes the details of the development and verification of the MBD model for the KORAD-21 transportation system under normal transport test conditions. This approach can be applicable to various transportation scenarios and systems, and the results of this study will help to ensure that nuclear fuel transportation is conducted safely and effectively.