• 생명과학회지
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• 제8권5호
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• pp.526-531
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• 1998

In this study, the composition and characteristics of poly-$\beta$-hydroxybutyrate (PHB) biosynthesized by Actinobacillus sp. EL-9 are investigated. PHB produced by Actinobacillus sp. EL-9 was identified as the homopolymer of 3-hydroxy-butyric acid (PHB) by infrared spectroscopy and nuclear magnetic resonance spectroscopy analysis. The melting tem-perature (T$_{m}$), and crystallization temperature(T$_{c}$) of PHB was 169.7$^{\circ}C$ and 69.13$^{\circ}C$, respectively. The viscosity on he basis of Brookfield viscometer was 6.01 ㎗/g. The viscosity-average molecular weight estimated by Mark-Ho-wink-Sakurada equation was 1.08$\times$10$^{6}$ ($\pm$3,000).00).

• 복식문화연구
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• 제14권2호
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• pp.286-298
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• 2006

The purpose of this study is to find the proper width of fabric which can bring high efficiency on productivity. We focus on the marking method by comparing and analyzing the marking efficiency of flare skirt. This study employs 4 criteria to mark the flare skirt, which are angle, location, width, and direction, respectively. There can be 3 different angles$(180^{\circ},\;270^{\circ},\;360^{\circ})$, and 2 different locations(the center line and the middle of the pattern) according to fixing of the warp line of the fabric. Also, width can be classified into 2 groups(110cm, 150cm), and marking direction can be grouped into 2(one direction marker and one direction per each size marker). These 4 criteria make $24(3{\times}2{\times}2{\times}2)$ cases for this study. Main findings are follows. Fist, the skirt with the 150cm width has higher efficiency rate than that of 110cm. Second, fixing the warp line at the center line has higher efficiency rate than that in the middle. Finally, per size marker has much higher efficiency than the just direction marker. In sum, we find that 150cm width with the center warp line and per size marker brings the highest efficiency rate.

• Radiation Oncology Journal
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• 제34권3호
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• pp.209-215
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• 2016

Purpose: We sought to determine if organ preservation (OP) with neoadjuvant chemoradiation (CRT) was feasible in patients with sinonasal cancer determined to require exenteration. Materials and Methods: Twenty patients were determined to require exenteration for definitive treatment from 2005 to 2014. Fourteen patients underwent OP and 6 patients received exenteration with adjuvant CRT. Exenteration free survival (EFS), locoregional control (LRC), progression-free survival (PFS), and overall survival (OS) were estimated. Results: Five patients (36%) receiving OP had complete disease response at time of surgery. With a median follow-up of 18.8 months, EFS was 62% at 2 years for patients undergoing OP. At 2 years, there were no significant differences in LRC, PFS or OS (all all p > 0.050) between the groups. Less grade 3 or greater toxicity was seen in patients undergoing OP (p = 0.003). Visual function was preserved in all patients undergoing OP. Conclusion: For patients with sinonasal cancer, OP may avoid exenteration, offering similar disease control and improved toxicity.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 1996년도 춘계 학술대회논문집
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• pp.99-104
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• 1996

The jet pump is being used in many fields for several purposes because of its simple construction and easy operation. The characteristics of the geometrical variables, pressure gradient and velocity distribution of the jet pump are studied using the CFD technique. The flow calculations through a bended nozzle. a mixing chamber and a venturi are presented and phenomenological aspects are discussed. This study solve 3-D steady incompressible Navier-Stokes equations using the Iterative time marching scheme. The governing equations are differenced with 1st-order accurate backward difference scheme for the time derivatives and 3rd-order accurate QUICK scheme for the convective terms. The Mark-and-cell concept was applied efficiently to solve continuity equation, which is differenced 2nd-order accurate central differenced scheme. The 4th-order artificial damping is added to the continuity equation for numerical stability. A O-type of grid system is generated inside a nozzle and venturi of the jet pump. It has concluded that the results of present study properly agree with physical flow phenomena.

• Toxicological Research
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• 제33권3호
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• pp.173-182
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• 2017

In silico methods to predict toxicity include the use of (Quantitative) Structure-Activity Relationships ((Q)SARs) as well as grouping (category formation) allowing for read-across. A challenging area for in silico modelling is the prediction of chronic toxicity and the No Observed (Adverse) Effect Level (NO(A)EL) in particular. A proposed solution to the prediction of chronic toxicity is to consider organ level effects, as opposed to modelling the NO(A)EL itself. This review has focussed on the use of structural alerts to identify potential liver toxicants. In silico profilers, or groups of structural alerts, have been developed based on mechanisms of action and informed by current knowledge of Adverse Outcome Pathways. These profilers are robust and can be coded computationally to allow for prediction. However, they do not cover all mechanisms or modes of liver toxicity and recommendations for the improvement of these approaches are given.

• Journal of Chest Surgery
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• 제30권8호
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• pp.747-751
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• 1997

폐동맥협착을 시행한 환아에서 수술직후 변화하는 혈역학에 대응하기 위하여 피하조직에 위치시켜 쉽게 조절할 수 있는 기구를 개발하였다. stainless steel wire를 이용하여 스프링을 만든후 이것의 표면을 PTFE로 덮은 형태로 제작하였으며 스프링 내부로 wire를 통과시켜 이것을 올가미 형식으로 죄는 방법으로 협착을 할 수 있게 하였으며 협착의 정도를 피하조직으로 통하는 투명한 tube에 1mm간격으로 표시하여 알수 있게 하였다. 6마리의 개의 하행대동맥에 협착을 시행하였다. 수술후 1,2일째에도 이완과 협착을 효과적으로 유도 할수 있었으며 3개월후 어느정도의 혈관손상은 있었으나 큰 협병증 없이 유지함을 보였다. 비록 실험적인 연구이지만 인체에 삽입할수 있는 재료로 쉽게 기구제작이 가능하며 앞으로 피하를 열고 조절가능한 폐동맥협착술에 이용할 수 있으리라 생각된다.

• Food Science and Biotechnology
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• 제18권1호
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• pp.89-94
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• 2009

Frequent outbreaks of foodborne illness have been increasing the awareness of food safety. Conventional methods for pathogen detection and identification are labor-intensive and take days to complete. Some immunological, rapid assays are developed, but these assays still require prolonged enrichment steps. Recently developed biosensors have shown potential for the rapid detection of foodborne pathogens. In this study, an impedimetric biosensor was developed for rapid detection of Salmonella entritidis in food sample. To develop the biosensor, an interdigitated microelectrode (IME) was fabricated by using a semiconductor fabrication process. Anti-Salmonella antibodies were immobilized based on neutravidin-biotin binding on the surface of the IME to form an active sensing layer. To evaluate the effect of electrode gap on sensitivity of the sensor, 3 types of sensors with different electrode gap sizes (2, 5, and $10{\mu}m$) were fabricated and tested. The impedimetric biosensor could detect $10^3\;CFU/mL$ of Salmonella in pork meat extract with an incubation time of 5 min. This method may provide a simple, rapid, and sensitive method to detect foodborne pathogens.

• 천문학회보
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• 제36권2호
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• pp.94.1-94.1
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• 2011

Recurrent substorms occur when high-speed solar wind streamers pass by Earth's magnetosphere. Most of the previous researches have been done using the observations obtained at the geosynchronous orbit focusing on the relationship between the solar wind disturbances and the occurrence of substorms. However, it is important to investigate the dynamics of the magnetotail because the magnetotail is the place where substorms develop. In this study we investigated the observations of recurrent dipolarizations in the near-Earth magnetotail that occurred during high-speed solar wind streamers. The dipolarizations and subsequent stretchings have occurred for more than three days with the average period of ~2 - 3 hours. The average period of ~2 - 3 hours is consistent with the average occurrence period of recurrent substorms. Also, the observed signatures on the geosynchronous orbit and the ground show recurrent substorms have occurred during the event. These suggest that the recurrent dipolarizations in the near-Earth magnetotail should be closely related to the recurrent substorms. On the other hand, there was no clear flow activities directly associated with the dipolarizations, except for some intermittent bursty flow activities. We will discuss the detailed characteristics of the dipolarizations and the relationship with recurrent substorms.

• 한국유체기계학회 논문집
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• 제18권3호
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• pp.5-11
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• 2015

Ocean waves have huge amounts of energy, even larger than wind or solar, which can be extracted by some mechanical device. This can be done by creating a system of reacting forces, in which two or more bodies move relative to each other, while at least one body interacts with the waves. This moves the floater up and down. The floaters are connected to an arm structure, which are mounted on a fixed hull structure. Hence, the structure of the floater is very important. A static structural analysis with FSI (Fluid-Structure Interaction) analysis is conducted. To achieve the pressure load for the FSI analysis, the floater is simulated on a wave generator using rigid body motion. The structural analysis is done to examine the stresses on the whole system, and four types of flange and floater are optimized. The result shows that the structure of floater with wood support is the safest.

• 대한조선학회논문집
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• 제44권3호
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• pp.296-304
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• 2007

The objective of this paper is to investigate the dynamic strength characteristics of LNG carriers cargo containment system under impact loads experimentally. The material properties were experimentally obtained for individual components of MARK III insulation system. A series of impact tests was performed using a custom-built drop experiment facility as varying heights and weights of the drop object. Crack initiation and propagation were measured during the cyclic dry drop experiment. The quantitative relationship between impact load and crack initiation as well as the cycle number and crack propagation were reported.