• Title/Summary/Keyword: MAN

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Predicting recurrence in oral cavity cancers: a review of 116 patients with buccal mucosa carcinoma in northwestern India

  • Pinakin Patel;Pranav Mohan Singhal;Kamal Kishor Lakhera;Aishwarya Chatterjee;Agil Babu;Suresh Singh;Shubhra Sharma;Bhoopendra Singh Gora;Naina Kumar Agarwal
    • Archives of Craniofacial Surgery
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    • v.24 no.5
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    • pp.211-217
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    • 2023
  • Background: Oral cavity cancers, the second most common type in India, are responsible for 10% of the overall cancer burden. With a recurrence rate of 30% to 40% and a 5-year survival rate of 50%, these malignancies account for substantial morbidity and mortality. Despite advances in treatment modalities, survival rates following treatment completion have not improved significantly. The present study aimed to establish specific epidemiological and pathological factors responsible for recurrence after treatment completion in buccal mucosa cancers. Methods: A retrospective analysis of the data of 116 patients treated for biopsy-proven cancers of the buccal mucosa was undertaken 1 year after treatment completion. Factors such as age, sex, education, lymphovascular invasion, extranodal extension (ENE), perineural invasion, depth of invasion, and pathological margin status were compared between patients who presented with recurrence and those who did not. Statistical significance was set at p< 0.05. Results: Of the 116 patients, 40 (34.5%) developed a recurrent disease within 1 year. The mean age of the study population was 43.3 years, and males constituted 91.4% of the included patients. Ipsilateral buccal mucosa was the commonest site of disease recurrence. Neck node metastasis, ENE, and margins of resection < 5 mm were significantly related to the recurrence of disease. However, surprisingly, lymphovascular invasion, perineural invasion, and depth of invasion > 10 mm did not show statistically significant associations. Conclusion: Neck node metastasis, ENE, and margins of resection < 5 mm were the histopathological factors associated with recurrence in cancers of the buccal mucosa.

A Study of Long-term Change in Carbon Dioxide Concentrations within and Across the Korean Peninsula between 1996 and 1997 (국내외 관측점간의 비교분석을 통한 이산화탄소의 장주기적 농도변화 특성에 관한)

  • 김기현;윤용훈;송기범
    • Journal of Korean Society for Atmospheric Environment
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    • v.17 no.1
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    • pp.105-115
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    • 2001
  • This study was conducted to analyzed the pattern of $CO_2$ concentration changes in various time scale within and across the Korean Peninsula. We compared that data sets obtained from Moo-Ahn(NAN) station in Korea with those determined from major background observatory stations around the world from the periods of Aug. 1995 to Dec. 1997. The mean $CO_2$concentrations of the MAN area, if computed using the total of 884 daily mean values, were computed to by 374.5$\pm$6.6 ppm. When the background data for MAN were compared with those of other background site, the concentration of MAN was systematically higher than any other comparable sites. Results of correlation analysis between MAN and other background sites generally showed up the existence of strong correlations, indicating that the relative effect of $CO_2$ concentration change can proceed similarly over the globe. However, notable differences in annual growth rate of $CO_2$ between MAN and all the comparative sites suggested that its concentration in th MAN area be regulated in more complicated manners than those in the other areas. It is thus suspected that the data collected form MAN area be not effective enough to represent areal distribution characteristics of $CO_2$in the Korean Peninsula.

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A study on wise sayings on the nature of book (책의 속성에 관한 연구)

  • 이만수
    • Journal of Korean Library and Information Science Society
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    • v.26
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    • pp.261-290
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    • 1997
  • 98 wise sayings on the nature of book are collected from various books and analyzed in their meanings. The results of analyzing them are as follows: A book is a good friend, teacher, doctor, and guide of life. A book is an implement of enhancing man s culture and a vehicle of civilization. A book makes man find his own self and shows his way of life. A book has its own life, develops it, and doesn't lose its life, but its destination depends on its reader. Great books make man know, dominate, civilize the world. Good books are not easy to come in contact with, but immortal and life-long as a good friend. Bad books are not difficult to come in contact with, but poisonous and dull. You can judge a man by the book he reads. A book to be of help is to make man think. Great books make man begin his new life. Nationalities occupations, and periods of activity of the authors who said wise sayings are investigated and analyzed. First, the nationalities of the authors are such advanced countries with high culture as England(41%), France(21%), America(19%), Germany(5%) and Rome(5%). Secondary, their occupations are as follows : a man of letters(62%), philosopher(13%), politician(5%), and churchman(4%), and especially poet forms 32% of men of letters. Thirdly, their activity periods are mainly 19C-20C and the period form 38% of the whole.

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An Analysis of Cultural Meaning on Advertisements for Man′s Cosmetics (남성화장품 광고의 의미 변화 분석)

  • 박수진;박길순
    • The Research Journal of the Costume Culture
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    • v.12 no.5
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    • pp.819-831
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    • 2004
  • Under the social conditions that an understanding of a men change socially and men's interests in their appearances are on the increase, this research intends to study and analyze the changes of people's sensibility of values on ads for men's cosmetics, which is said to be performed the social, cultural function reflecting the social consciousness, the value and the idea creating a new one. The documents for the research was sindonga. The ad showed that they've changed making a difference according to the times. In 1970s, it expressed a man for cleanness and modernity living in urbanized and modernized society. On the other hand, it expressed a man who won success socially and enjoyed a comfortable life in a dignified manner, or a man who was fond of sports leisure activity pursuing a clam and composed life and was interested in the skin and an appearance in 1980s. From 1990 to 2002, it expressed a man of challengeable manly beauty having a strong will toward social achievement, or a man who has a sweet manly beauty with sex appeal to a woman. Besides, it expressed a man who is soft, faithful and affectionate with a liberal and peaceful atmosphere as well.

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An Analysis on Structures of Man's Costume in Byzantine Empire

  • Yoon, Jeom-Soon
    • Journal of Fashion Business
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    • v.8 no.6
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    • pp.57-67
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    • 2004
  • The forms of man's costumes in Byzantine Empire were changed according to each composition of costumes. Those forms of costumes had common features of each period when costumes were included. At the same time, however, the fact that differences existed in accordance with a social position including gender, class, occupation, etc. even though in same period were showed. Analytic elements of man's costumes in Byzantine Empire were selected by important factors. This showed the meanings of position and class in that time. The kinds of analytic elements in man's outwear were various but the forms of costumes were not developed because christianity influenced the forms of clothing in the Middle Ages. As the result of synthesis, the main factor of man's costumes was a tunic in Byzantine Empire of the Middle Ages The phases of the times were reflected on the structure of man's costumes in Byzantine Empire. In particular, religious feature was emphasized, and analytic elements of costumes having meanings showed the features of the society at the Middle Ages. For example, a central analytic element of man's costume, an outer garment was a tunic style of H-silhouette that hid the body line. This was influenced by the phases of the times. Namely, the costume stands as a symbol of the times, and also is a cultural sign that reflects phases like politics, economy, religion.

Analysis of Workforce Scheduling Using Adjusted Man-machine Chart and Simulation (보완 다중 활동 분석표와 시뮬레이션을 이용한 작업자 운영 전략 분석)

  • Hyowon Choi;Heejae Byeon;Suhan Yoon;Bosung Kim;Soondo Hong
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.47 no.1
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    • pp.20-27
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    • 2024
  • Determining the number of operators who set up the machines in a human-machine system is crucial for maximizing the benefits of automated production machines. A man-machine chart is an effective tool for identifying bottlenecks, improving process efficiency, and determining the optimal number of machines per operator. However, traditional man-machine charts are lacking in accounting for idle times, such as interruptions caused by other material handling equipment. We present an adjusted man-machine chart that determines the number of machines per operator, incorporating idleness as a penalty term. The adjusted man-machine chart efficiently deploys and schedules operators for the hole machining process to enhance productivity, where operators have various idle times, such as break times and waiting times by forklifts or trailers. Further, we conduct a simulation validation of traditional and proposed charts under various operational environments of operators' fixed and flexible break times. The simulation results indicate that the adjusted man-machine chart is better suited for real-world work environments and significantly improves productivity.

Molecular cloning and characterization of β-mannanase B from Cellulosimicrobium sp. YB-43 (Cellulosimicrobium sp. YB-43의 mannanase B 유전자 클로닝과 특성 분석)

  • Yoon, Ki-Hong
    • Korean Journal of Microbiology
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    • v.52 no.3
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    • pp.336-343
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    • 2016
  • A mannanase gene was cloned into Escherichia coli from Cellulosimicrobium sp. YB-43, which had been found to produce two kinds of mannanase, and sequenced completely. This mannanase gene, designated manB, consisted of 1,284 nucleotides encoding a polypeptide of 427 amino acid residues. Based on the deduced amino acid sequence, the ManB was identified to be a modular enzyme including two carbohydrate binding domains besides the catalytic domain, which was highly homologous to mannanases belonging to the glycosyl hydrolase family 5. The N-terminal amino acid sequence of ManB, purified from a cell-free extract of the recombinant E. coli carrying a Cellulosimicrobium sp. YB-43 manB gene, has been determined as QGASAASDG, which was correctly corresponding to signal peptide predicted by SignalP4.1 server for Gram-negative bacteria. The purified ManB had a pH optimum for its activity at pH 6.5~7.0 and a temperature optimum at $55^{\circ}C$. The enzyme was active on locust bean gum (LBG), konjac and guar gum, while it did not exhibit activity towards carboxymethylcellulose, xylan, starch, and para-nitrophenyl-${\beta}$-mannopyranoside. The activity of enzyme was inhibited very slightly by $Mg^{2+}$, $K^+$, and $Na^+$, and significantly inhibited by $Cu^{2+}$, $Zn^{2+}$, $Mn^{2+}$, and SDS. The enzyme could hydrolyze mannooligosaccharides larger than mannobiose, which was the most predominant product resulting from the ManB hydrolysis for mannooligosaccharides and LBG.

Antioxidant Action of Reaction Mixtures of Gums Hydrolysates and Urea Derivatives (중합도별 gum류 가수분해 올리고당과 urea관련화합물과의 반응혼합물이 항산화능에 미치는 영향)

  • Kim, Sang-Woo;Park, Gwi-Gun
    • Applied Biological Chemistry
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    • v.47 no.4
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    • pp.384-389
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    • 2004
  • The purified ${\beta}-mannanase$ hydrolyzed various gums to mannose, ${\beta}-1,4-mannobiose$, $Gal^3Man_4$, and D.P 7 of galactosyl mannooligosaccharide, and isolated from the enzymatic hydrolysate for 24 hrs reaction by activated carbon column chromatography and Sephadex G-25 column chromatography. For the elucidate of antioxidant action of ${\beta}-1,4-mannobiose$, $Gal^3Man_4$ and DP 7 of galactosyl mannooligosaccharide and urea derivatives, coloration, reducing power, antioxidant activity and DPPH test were accomplished. The coloration was high at reaction mixture of ${\beta}-1,4-mannobiose$, $Gal^3Man_4$ D.P 7 and urea. TLC of reaction mixture of ${\beta}-1,4-mannobiose$, $Gal^3Man_4$ D.P 7 and ureas showed new reaction products, respectively. but except reaction mixture of ${\beta}-1,4-mannobiose$ and urea. The reducing power was high at reaction mixture of ${\beta}-1,4-mannobiose$, $Gal^3Man_4$ D.P 7 and phenylthiourea. The reaction mixture of ${\beta}-1,4-mannobiose$, $Gal^3Man_4$ D.P 7 and thiourea showed similar radical scavenging activities on DPPH to activity of AsA. The reaction mixture of ${\beta}-1,4-mannobiose$, $Gal^3Man_4$ D.P 7 and thiourea, phenythiolurea shown strong antioxidative activites on the oxidation of linoneic acid.

A Study on the Method of Computing Standard Wartime Maintenance Man-Hour Incorporating Wartime Maintenance Condition (전장 정비환경을 고려한 전시 표준정비인시 산출방안 연구)

  • Kim, Min-Hyuk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.477-483
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    • 2021
  • In a military maintenance system, the standard maintenance man-hour of weapon systems is a tool to estimate the maintenance capabilities of maintenance units, provide standards for determining the maintenance needs and workload, and provide basic data for establishing a maintenance plan. The standard maintenance man-hours of major weapon systems have already been derived and used, but the standard maintenance man-hour in a wartime maintenance environment has not been computed. Therefore, the standard wartime maintenance man-hours need to be derived and This study proposes a process and method of computing the maintenance man-hours. In addition, this work suggests the criteria of collecting and screening data that is necessary for estimating the standard maintenance man-hours and introduces a methodology for analyzing the characteristics of maintenance man-hour distribution in the process. The proposed process first designs a model that reflects the wartime maintenance environment, selects statistical techniques, collects maintenance data, analyzes the descriptive statistics, estimates the distribution, and finally presents representative values of maintenance man-hour. Based on the proposed method, the standard wartime maintenance man-hours of the four weapon systems were calculated, and the distribution of the maintenance man-hours was analyzed to follow a lognormal distribution, and the method presented reliable results.

A Model for Man-Machine System Evaluation (II) (인간 - 기계시스템의 평가모델 (II))

  • 이상도;하정진;정중희;이동춘
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.9 no.13
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    • pp.17-22
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    • 1986
  • Man-machine system is an integrated total system which is linked by functions of man and machine, and the value of the system is determined by its compatability. And it is able to evaluate the system value on the aspects of utility, availability, and cost benefit. The authors previously represented the methodology of system utility using transfer functions, and this paper successively discusses the reliability of man-machine system. The reliability estimation and evaluation methodologies are briefly mentioned, and some examples are shown in this paper.

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