• 대한두개안면성형외과학회지
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• 제24권5호
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• pp.211-217
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• 2023

Background: Oral cavity cancers, the second most common type in India, are responsible for 10% of the overall cancer burden. With a recurrence rate of 30% to 40% and a 5-year survival rate of 50%, these malignancies account for substantial morbidity and mortality. Despite advances in treatment modalities, survival rates following treatment completion have not improved significantly. The present study aimed to establish specific epidemiological and pathological factors responsible for recurrence after treatment completion in buccal mucosa cancers. Methods: A retrospective analysis of the data of 116 patients treated for biopsy-proven cancers of the buccal mucosa was undertaken 1 year after treatment completion. Factors such as age, sex, education, lymphovascular invasion, extranodal extension (ENE), perineural invasion, depth of invasion, and pathological margin status were compared between patients who presented with recurrence and those who did not. Statistical significance was set at p< 0.05. Results: Of the 116 patients, 40 (34.5%) developed a recurrent disease within 1 year. The mean age of the study population was 43.3 years, and males constituted 91.4% of the included patients. Ipsilateral buccal mucosa was the commonest site of disease recurrence. Neck node metastasis, ENE, and margins of resection < 5 mm were significantly related to the recurrence of disease. However, surprisingly, lymphovascular invasion, perineural invasion, and depth of invasion > 10 mm did not show statistically significant associations. Conclusion: Neck node metastasis, ENE, and margins of resection < 5 mm were the histopathological factors associated with recurrence in cancers of the buccal mucosa.

• 한국대기환경학회지
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• 제17권1호
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• pp.105-115
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• 2001

This study was conducted to analyzed the pattern of $CO_2$ concentration changes in various time scale within and across the Korean Peninsula. We compared that data sets obtained from Moo-Ahn(NAN) station in Korea with those determined from major background observatory stations around the world from the periods of Aug. 1995 to Dec. 1997. The mean $CO_2$concentrations of the MAN area, if computed using the total of 884 daily mean values, were computed to by 374.5$\pm$6.6 ppm. When the background data for MAN were compared with those of other background site, the concentration of MAN was systematically higher than any other comparable sites. Results of correlation analysis between MAN and other background sites generally showed up the existence of strong correlations, indicating that the relative effect of $CO_2$ concentration change can proceed similarly over the globe. However, notable differences in annual growth rate of $CO_2$ between MAN and all the comparative sites suggested that its concentration in th MAN area be regulated in more complicated manners than those in the other areas. It is thus suspected that the data collected form MAN area be not effective enough to represent areal distribution characteristics of $CO_2$in the Korean Peninsula.

• 한국도서관정보학회지
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• 제26권
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• pp.261-290
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• 1997

98 wise sayings on the nature of book are collected from various books and analyzed in their meanings. The results of analyzing them are as follows: A book is a good friend, teacher, doctor, and guide of life. A book is an implement of enhancing man s culture and a vehicle of civilization. A book makes man find his own self and shows his way of life. A book has its own life, develops it, and doesn't lose its life, but its destination depends on its reader. Great books make man know, dominate, civilize the world. Good books are not easy to come in contact with, but immortal and life-long as a good friend. Bad books are not difficult to come in contact with, but poisonous and dull. You can judge a man by the book he reads. A book to be of help is to make man think. Great books make man begin his new life. Nationalities occupations, and periods of activity of the authors who said wise sayings are investigated and analyzed. First, the nationalities of the authors are such advanced countries with high culture as England(41%), France(21%), America(19%), Germany(5%) and Rome(5%). Secondary, their occupations are as follows : a man of letters(62%), philosopher(13%), politician(5%), and churchman(4%), and especially poet forms 32% of men of letters. Thirdly, their activity periods are mainly 19C-20C and the period form 38% of the whole.

• 복식문화연구
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• 제12권5호
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• pp.819-831
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• 2004

Under the social conditions that an understanding of a men change socially and men's interests in their appearances are on the increase, this research intends to study and analyze the changes of people's sensibility of values on ads for men's cosmetics, which is said to be performed the social, cultural function reflecting the social consciousness, the value and the idea creating a new one. The documents for the research was sindonga. The ad showed that they've changed making a difference according to the times. In 1970s, it expressed a man for cleanness and modernity living in urbanized and modernized society. On the other hand, it expressed a man who won success socially and enjoyed a comfortable life in a dignified manner, or a man who was fond of sports leisure activity pursuing a clam and composed life and was interested in the skin and an appearance in 1980s. From 1990 to 2002, it expressed a man of challengeable manly beauty having a strong will toward social achievement, or a man who has a sweet manly beauty with sex appeal to a woman. Besides, it expressed a man who is soft, faithful and affectionate with a liberal and peaceful atmosphere as well.

• 패션비즈니스
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• 제8권6호
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• pp.57-67
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• 2004

The forms of man's costumes in Byzantine Empire were changed according to each composition of costumes. Those forms of costumes had common features of each period when costumes were included. At the same time, however, the fact that differences existed in accordance with a social position including gender, class, occupation, etc. even though in same period were showed. Analytic elements of man's costumes in Byzantine Empire were selected by important factors. This showed the meanings of position and class in that time. The kinds of analytic elements in man's outwear were various but the forms of costumes were not developed because christianity influenced the forms of clothing in the Middle Ages. As the result of synthesis, the main factor of man's costumes was a tunic in Byzantine Empire of the Middle Ages The phases of the times were reflected on the structure of man's costumes in Byzantine Empire. In particular, religious feature was emphasized, and analytic elements of costumes having meanings showed the features of the society at the Middle Ages. For example, a central analytic element of man's costume, an outer garment was a tunic style of H-silhouette that hid the body line. This was influenced by the phases of the times. Namely, the costume stands as a symbol of the times, and also is a cultural sign that reflects phases like politics, economy, religion.

• 산업경영시스템학회지
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• 제47권1호
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• pp.20-27
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• 2024

Determining the number of operators who set up the machines in a human-machine system is crucial for maximizing the benefits of automated production machines. A man-machine chart is an effective tool for identifying bottlenecks, improving process efficiency, and determining the optimal number of machines per operator. However, traditional man-machine charts are lacking in accounting for idle times, such as interruptions caused by other material handling equipment. We present an adjusted man-machine chart that determines the number of machines per operator, incorporating idleness as a penalty term. The adjusted man-machine chart efficiently deploys and schedules operators for the hole machining process to enhance productivity, where operators have various idle times, such as break times and waiting times by forklifts or trailers. Further, we conduct a simulation validation of traditional and proposed charts under various operational environments of operators' fixed and flexible break times. The simulation results indicate that the adjusted man-machine chart is better suited for real-world work environments and significantly improves productivity.

• 미생물학회지
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• 제52권3호
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• pp.336-343
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• 2016

두 종류의 mannanases를 생산하는 Cellulosimicrobium sp. YB-43로부터 mannanase 유전자를 클로닝하고 그 염기서열을 결정하였다. Mannanase 유전자는 manB로 명명되었으며, 427 아미노 잔기로 구성된 단백질을 코드하는 1,284개 염기로 구성되었다. ManB는 추론된 아미노산 배열에 근거해서 glycosyl hydrolase family 5에 속하는 mannanase와 상동성이 높은 활성영역과 함께 2개의 탄수화물 결합영역을 포함하고 있는 다영역 효소로 확인되었다. Cellulosimicrobium sp. YB-43의 manB 유전자를 함유한 재조합 대장균의 균체 파쇄상등액으로부터 정제된 ManB의 아미노 말단 배열이 QGASAASDG로 결정되었으며 이는 SignalP4.1 server로 그람 음성균을 기준으로 예측된 signal peptide의 결과와 정확하기 일치하였다. 정제된 ManB의 최적 반응조건은 $55^{\circ}C$와 pH 6.5-7.0이며 locust bean gum (LBG), konjac과 guar gum을 가수분해 하였으며, 셀룰로스, 자일란, 전분과 para-nitrophenyl-${\beta}$-mannopyranoside에 대해서는 분해활성이 없었다. ManB의 활성은 $Mg^{2+}$, $K^+$와 $Na^+$에 의해 약간 저해되었으며 $Cu^{2+}$, $Zn^{2+}$, $Mn^{2+}$과 SDS에 의해서는 크게 저해되었다. 또한 이 효소는 mannobiose 보다 큰 중합도를 갖는 만노올리고당을 가수분해하였으며, LBG와 만노올리고당을 가수분해하였을 때 mannobiose가 가장 많은 양으로 생성되었다.

• Applied Biological Chemistry
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• 제47권4호
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• pp.384-389
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• 2004

$100^{\circ}C$에서 반응시켜 2, 4, 6, 8시간의 갈변도 변화는 ${\beta}-1,4-mannobiose$와 urea의 반응혼합물이 시간의 경과함에 따라 강한 착색도의 증가를 나타냈으나 phenylthiourea, thiourea의 반응액은 착색속도가 늦었다. 같은 조건하에서 $Gal^3Man_4$와 urea 관련화합물의 각 반응혼합물의 갈변도를 나타낸 것으로 urea가 강한 착색도의 중가를 보였고 phenylthiourea, thiourea의 반응액은 비교적 높은 착색도를 보였다. DP 7의 galactosyl mannooligosaccharide와의 각 반응혼합물의 갈변도는 urea의 반응액이 강한 착색을 보였으며 phenylthiourea, thiourea의 반응액의 순으로 착색를 나타내었다. 반응혼합물의 TLC 결과에서 ${\beta}-1,4-mannobiose$와 urea의 반응혼합물 이외에 phenylthiourea, thiourea의 반응액은 새로운 화합물이 생성되었고, $Gal^3Man_4$와 D.P 7 galactosyl manooligosaccharide와의 반응혼합물에서는 모든 반응액에서 새로운 화합물이 출현되었다. 반응혼합물의 환원력은 urea관련화합물 중에서 특히 phenylthiourea, thiourea가 ${\beta}-1,4-mannobiose,\;Gal^3Man_4$, DP 7의 galactosyl manooligosaccharide와의 반응혼합물에서 강한 환원력이 나타났다. Linoleic acid에 대한 반응혼합물의 항산화력 측정에서 ${\beta}-1,4-mannobiose$와 thiourea의 반응혼합물의 항산화력이 Ascorbic acid(AsA)수준의 항산화력을 나타내었고, $Gal^3Man_4$와 thiourea, phenylthiourea의 반응혼합물은 AsA와 유사한 항산화능을 나타내었다. DP 7의 galactosyl manooligosaccharide와 thiourea, phenylthiourea의 반응혼합물의 항산화력은 AsA에 미치지는 못하였다. ${\beta}-1,4-Mannobiose$와 thiourea, phenylthiourea의 반응혼합물이 강한 전자공여능을 나타내고 있고, $Gal^3Man_4$와 phenylthiourea의 반응혼합물 및 D.P 7의 galactosyl manooligosaccharide와 phenylthiourea와의 반응혼합물이 전자공여능을 나타내고 있다.

• 한국산학기술학회논문지
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• 제22권6호
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• pp.477-483
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• 2021

군의 정비체계에서 표준정비인시는 정비부대의 정비능력을 판단하는 도구로서 정비 소요와 작업량을 결정하는 기준을 제공하고, 정비계획 수립의 기초 자료로 활용된다. 군 주요 장비의 평시 표준정비인시는 이미 선정되어 활용하고 있으나 전시 정비환경에서 표준정비인시는 미선정되어 이를 산출할 필요성이 제기되었다. 이는 전시에 정비 시설, 공구, 장비, 인력 등이 충분치 않고, 정비 목표와 수준이 평시와는 상이하므로 평시 표준정비인시를 직접 적용하는 것은 적절하지 못하기 때문이다. 따라서 본 연구는 전시 표준정비인시 산정을 위해 필요한 데이터를 수집·선별하는 과정과 기준을 제시하고, 표준정비인시 산출 프로세스에서 정비인시 분포의 특징을 분석하여 표준정비인시로서의 대푯값을 선정하는 방법을 제안한다. 제시되는 전시 정비인시 산출 프로세스는 먼저 전시 정비환경을 고려한 기준과 가정사항 등을 반영한 모델을 설계하고, 표준정비인시 도출의 통계적 기법을 결정하며, 전시와 유사한 환경의 평시 정비실적 데이터를 수집하여 기술통계 분석과 정비인시 분포를 추정 및 검증하고 최종적으로 대푯값을 제시하는 방법을 사용한다. 제안된 방법을 토대로 육군이 운용 중인 4개 주요 전투장비의 전시 표준정비인시를 도출하였으며, 해당 장비들의 정비인시 분포가 로그 정규분포를 따르고 있는 것으로 분석되어 신뢰성 있는 결과값을 제시하였다.

• 산업경영시스템학회지
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• 제9권13호
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• pp.17-22
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• 1986

Man-machine system is an integrated total system which is linked by functions of man and machine, and the value of the system is determined by its compatability. And it is able to evaluate the system value on the aspects of utility, availability, and cost benefit. The authors previously represented the methodology of system utility using transfer functions, and this paper successively discusses the reliability of man-machine system. The reliability estimation and evaluation methodologies are briefly mentioned, and some examples are shown in this paper.