• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5375-5378
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• 2013

Background: This study was undertaken to evaluate the surgical outcomes of patients with stage IA2 cervical cancer treated with radical hysterectomy. Data for 58 patients who underwent modified radical hysterectomy or radical hysterectomy with pelvic lymphadenectomy between January 2003 and December 2012 at Chiang Mai University Hospital were retrospectively reviewed. The analysis included clinico-pathological risk factors (nodal metastasis, parametrial involvement), adjuvant treatment, 5-year disease-free survival and 5-year overall survival. All pathologic slides were reviewed by a gynecologic pathologist. Follow-up methods included at least cervical cytology and colposcopy with directed biopsy if indicated. Univariate analysis was performed to identify factors associated with median survival. At the median follow up time of 73 months, the 5-year disease-free survival and the 5-year overall survival were 97.4% and 97.4%, respectively. Two (3.4%) patients had pelvic lymph node metastases. In a univariate analysis, there was no statistically significant association between survival and prognostic factors such as age, histological cell type, lymph-vascular space invasion, vaginal margin status and lymph node status. Surgical and survival outcomes of women with stage IA2 cervical cancer are excellent. No parametrial involvement was detected in our study. Patients with stage IA2 cervical cancer may be treated with simple or less radical hysterectomy with pelvic lymphadenectomy.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
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• pp.629-632
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• 2007

While conventional interferometric SAR (InSAR) technique is an excellent tool for displacement observation, it is only sensitive to one-dimensional deformation along the satellite's line-of-sight (LOS). Recently, a multiple aperture interferogram (MAI) technique has been developed to overcome this drawback. This method successfully extracted along-track displacements from InSAR data, based on split-beam InSAR processing, to create forward- and backward- looking interferograms, and was superior to along-track displacements derived by pixel-offset algorithm. This method is useful to measure along-track displacements. However, it does not only decrease the coherence of MAI because three co-registration and resampling procedures are required for producing MAI, but also is confined to a suitable interferometric pair of SAR images having zero Doppler centroid. In this paper, we propose an efficient and robust method to generate MAI from interferometric pair having non-zero Doppler centroid. The proposed method efficiently improves the coherence of MAI, because the co-registration of forward- and backward- single look complex (SLC) images is carried out by time shift property of Fourier transform without resampling procedure. It also successfully removes azimuth flat earth and topographic phases caused by the effect of non-zero Doppler centroid. We tested the proposed method using ERS images of the Mw 7.1 1999 California, Hector Mine Earthquake. The result shows that the proposed method improved the coherence of MAI and generalized MAI processing algorithm.

• Archives of Pharmacal Research
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• 제29권1호
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• pp.80-87
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• 2006

Leukemias are common worldwide. Wilms'tumor1 (WT1) protein is highly expressed in leukemic blast cells of myeloid and lymphoid origin. Thus, WT1 mRNA serves as a tumor marker for leukemias detection and monitoring disease progression. Curcumin is well known for its anticancer property. The objective of this study was to investigate the effect of curcumin on WT1 gene expression in patient leukemic cells. The leukemic cells were collected from 70 childhood leukemia patients admitted at Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand, in the period July 2003 to February 2005. There were 58 cases of acute lymphoblastic leukemia (ALL), 10 cases of acute myeloblastic leukemia (AML), and 2 cases of chronic myelocytic leukemia (CML). There were 41 males and 29 females ranging from 1 to 15 years old. Leukemic cells were cultured in the presence or absence of 10 mM curcumin for 48 h. WT1 mRNA levels were determined by RT-PCR. The result showed that curcumin reduced WT1 gene expression in the cells from 35 patients (50%). It affected the WT1 gene expression in 4 of 8 relapsed cases (50%), 12 of 24 cases of drug maintenance (50%), 7 of 16 cases of completed treatment (44%), and 12 of 22 cases of new patients (54%). The basal expression levels of WT1 gene in leukemic patient cells as compared to that of K562 cells were classified as low level (1-20%) in 6 of 20 cases (30%), medium level (21-60%) in 12 of 21 cases (57%), and high level (61-100%) in 17 of 23 cases (74%). In summary, curcumin decreased WT1 mRNA in patient leukemic cells. Thus, curcumin treatment may provide a lead for clinical treatment in leukemic patients in the future.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2008년도 Asian Magnetics Conference
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• pp.173.1-173.1
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• 2008

• 한국해양환경ㆍ에너지학회지
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• 제8권1호
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• pp.9-16
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• 2005

본 연구는 최근 한국에서 퇴적물 독성 실험생물로 개발되고 있는 저서 단각류 Mandibulophoxus mai와 Monocorophium acherusicum의 생존과 성장 및 민감도(sensitivity)에 대한 온도의 영향를 평가하기 위한 일련의 실험으로 수행되었다. 본 연구에 사용된 각 실험 단각류의 생물학적 영향으로 각기 다른 수온 조건에서의 생존과 성장률을 통해 결정하였다. 표준 독성물질인 카트뮴(Cd)을 평가하는데 있어서 독성 민감도에 대한 온도의 영향은 각기 다른 온도에서 카드뮴이 첨가되지 않은 해수와 카드뮴이 첨가된 해수에 노출된 단각류의 생존률을 비교하여 결정하였다. 연구결과, 온도는 두 실험 단각규 모두의 생존, 성장 및 카드뮴 민감도에 영향을 미치는 것으로 평가되었다(p<0.05). 두 실험종 모두 80％이상의 생존율을 보인 온도범위는 13-22℃인 것으로 확인되었다. 두 실험종의 일일 성장률은 M. mai의 경우 20℃, M. acherusicum의 경우 25℃에서 다른 온도 조건에 비해 상대적으로 높게 나타났다. 반면, Cd 민감노에 대한 영향은 M. mai는 20℃, M. acherusicum은 15℃가 다른 온도 조건에 비해 상대적으로 큰 것으로 평가되었다. 이상의 연구 결과에 근거할 때, 온도는 단각규를 이용한 치사 및 반치사 생물 검정 연구에 있어 매우 중요한 변수인 것으로 판단되었다. 따라서, 독성평가에 활용되는 생물종에 대한 적절한 실험 온도 범위를 결정하는 것은 표준 독성시험법을 개발하는데 우선적으로 고려되어야 학 사항인 것으로 사료된다.

• Environmental Engineering Research
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• 제15권2호
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• pp.93-98
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• 2010

This study aims to determine the chemical composition and seasonal variation of atmospheric acid deposition in order to identify possible sources contributing to precipitation. Sampling and analysis of 132 wet deposition samples were carried out from January to December 2008 at Mae Hia Research Center, Chiang Mai University, Chiang Mai Province. Total precipitation was 1,286.7 mm. Mean electro-conductivity and pH values were 0.94 mS/m and 6.27, respectively. Major cations ($Na^+$, ${NH_4}^+$, $K^+$, $Ca^{2+}$, and $Mg^{2+}$) and major anions ($HCOO^-$, $CH_3COO^-$, $Cl^-$, ${NO_3}^-$, and ${SO_4}^{2-}$) were determined by Ion Chromatography. The relative volume weight mean concentrations of anions, in descending order, were ${SO_4}^{2-}$ > ${NO_3}^-$ > $Cl^-$ > $CH_3COO^-$ > $HCOO^-$ and those of cations were $NH_4^+$ > $Ca^{2+}$ > $Mg^{2+}$ > $K^{+}$ > $Na^+$. Results of a principle component analysis highlighted the influence of various possible sources of ions such as agricultural activity, fuel combustion, marine sources, soil resuspension, and biomass burning.

• 한국광학회지
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• 제15권3호
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• pp.229-233
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• 2004

본 논문에서는 코히런트 시간 광 CDMA 시스템에서 발생되는 다중접근 간섭(MAI)을 제거하기 위한 전 광학적인 차동 검출 방법을 제안한다. 비선형 광학루프 거울(NOLM)은 두 제어 포트로 인가되는 광파워의 차를 출력으로 내 보내는 역할, 즉 전 광학적 차동 검출기로서 동작한다. 따라서, 같은 파형과 광 파워로 입력되는 MAI는 NOLM에서 차동 검출되어 제거된다. 실험을 위하여 두 개의 채널이 인코딩/디코딩 되었다. 디코딩된 신호는 NOLM의 두 제어 포트에 보내어지고, 출력단에서 MAI가 크게 제거된 반면, 높은 자기상관 피크를 가진 신호가 관측되었다. NOLM 통과 후, 신호-대-간섭 비는 7 ㏈만큼 개선되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5123-5126
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• 2014

Background: To evaluate the diagnostic performance of IOTA simple rules in differentiating between benign and malignant ovarian tumors. Materials and Methods: A study of diagnostic performance was conducted on women scheduled for elective surgery due to ovarian masses between March 2007 and March 2012. All patients underwent ultrasound examination for IOTA simple rules within 24 hours of surgery. All examinations were performed by the authors, who had no any clinical information of the patients, to differentiate between benign and malignant adnexal masses using IOTA simple rules. Gold standard diagnosis was based on pathological or operative findings. Results: A total of 398 adnexal masses, in 376 women, were available for analysis. Of them, the IOTA simple rules could be applied in 319 (80.1%) including 212 (66.5%) benign tumors and 107 (33.6%) malignant tumors. The simple rules yielded inconclusive results in 79 (19.9%) masses. In the 319 masses for which the IOTA simple rules could be applied, sensitivity was 82.9% and specificity 95.3%. Conclusions: The IOTA simple rules have high diagnostic performance in differentiating between benign and malignant adnexal masses. Nevertheless, inconclusive results are relatively common.

• 한국정보통신학회논문지
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• 제9권6호
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• pp.1174-1181
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• 2005

대량의 데이터를 빠르게 전송할 수 있는 UWB(Ultra-widebandwidth) 시간 도약(time hopping : TH) 펄스 위치 변조(pulse position modulation : PPM) 다중 통신 시스템의 비트 오율을 정확히 계산할 수 있는 방법을 소개한다. 본 논문에서 다중 접근 간섭(multiple access interference : MAI)의 통계적 성질을 특성함수 기법을 이용하여 정확히 모델링 하였고 이를 바탕으로 TH-PPM 시스템의 비트 오율을 정확하게 계산할 수 있는 해석 식을 제시하였다. 또한, 기존의 MAI에 대한 가우시안 근사에 비하여 상당히 개선된 정확성을 갖는 근사식을 함께 소개하였다. 본 논문에서 제시한 모델에 의해서 계산된 비트 오율을 Monte-Carlo 시뮬레이션 한 결과와 비교함으로써 제안한 BER 식의 정확성 및 타당성을 검증하였다.

• 한국축산식품학회지
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• 제41권2호
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• pp.237-246
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• 2021

The taste-active and nutritional components of Thai native, broilers, black-boned, and spent hen chickens were analyzed. The amounts of tasty amino acids especially glutamic acid were the highest in Thai native chicken. The black-boned chicken had the highest arginine content, related to the least amount of consumer satisfaction. Concerning nutritional quality, choline, and taurine were deemed important for brain function. The black-boned chicken showed the highest choline and taurine contents, unlike that of the spent hens. In contrast, broilers presented the highest betaine content, which might be attributed to their lipid metabolism. L-carnitine content was abundant in black-boned and Thai native chickens. Moreover, the amounts of essential amino acids were high in Thai native chicken. In conclusion, black-boned chicken proved to be an excellent nutritional source for health-conscience consumers, whereas the Thai native chickens were flavourful and delicious.