• Title/Summary/Keyword: M71

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Effects of Didecyldimethylammonium Chloride (DDAC) on Sprague-Dawley Rats after 13 Weeks of Inhalation Exposure

  • Kim, Yong-Soon;Lee, Sung-Bae;Lim, Cheol-Hong
    • Toxicological Research
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    • v.33 no.1
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    • pp.7-14
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    • 2017
  • Didecyldimethylammonium chloride (DDAC) is used in many types of biocidal products including tableware, carpets, humidifiers, and swimming pools, etc. In spite of increased chances of DDAC exposure through inhalation, studies on the inhalation toxicity of DDAC are not common even though the toxicity of DDAC might be significantly higher if it were to be administered through routes other than the respiratory system. DDAC aerosols were exposed to Sprague-Dawley rats in whole body exposure chambers for a duration of 13 weeks. The Mass Median Aerodynamic Diameters of the DDAC aerosol were $0.63{\mu}m$, $0.81{\mu}m$, and $1.65{\mu}m$, and the geometric standard deviations were 1.62, 1.65, and 1.65 in the low ($0.11{\pm}0.06mg/m^3$), the middle ($0.36{\pm}0.20mg/m^3$) and the high ($1.41{\pm}0.71mg/m^3$) exposure groups, respectively. Body weight was confirmed to be clearly influenced by exposure to DDAC and mean body weight was approximately 35% lower in the high ($1.41{\pm}0.71mg/m^3$) male group and 15% lower in the high ($1.41{\pm}0.71mg/m^3$) female group compared to that of the control group. In the bronchoalveolar lavage fluid assay, the levels of albumin and lactate dehydrogenase had no effect on DDAC exposure. The lung weight increased for the middle ($0.36{\pm}0.20mg/m^3$) and the high ($1.41{\pm}0.71mg/m^3$) concentrations of the DDAC exposure group, and inflammatory cell infiltration and interstitial pneumonia were partially observed in the lungs of the middle ($0.36{\pm}0.20mg/m^3$) and the high ($1.41{\pm}0.71mg/m^3$) exposure groups. However, severe histopathological symptoms, including proteinosis and/or fibrosis, were not found. Based on the results of the changes in the body weight and lung weight, it is considered that the NOAEL (no-observed adverse effect) level for the 13-week exposure duration is $0.11mg/m^3$.

Evaluation of Sewage Treatment Plant Efficiency in the Variation of Sewage Inflow and Sludge Interface Height by Rainfall (강우로 인한 유입하수량 증가와 슬러지 계면높이 변화에 따른 하수처리장 효율평가)

  • Park, Hye-Sook;Song, Seok Heon
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.8
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    • pp.549-553
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    • 2014
  • Variation of sewage sludge interface height and flow rate by rainfall were applied to the actual public sewage treatment plant, and the efficiency of sewage treatment was evaluated by measuring $BOD_5$, $COD_{Mn}$, SS, T-N, and T-P. When both flow and interfacial height are increased, the treatment efficiencies in terms of the five water pollutants are decreased. Among them SS is the most critical pollutant in rainfall. When 0.5 Q inflow was applied, the efficiencies were 74.2% at the sludge interface height of 0.5 m, 76.4% at 1.0 m, 70.2% at 1.5 m, and 60.7% at 2.0 m. When 1.0 Q inflow was applied, the efficiencies were 71.7% at the sludge interface height of 0.5 m, 71.9% at 1.0 m, 46.4% at 1.5 m, and -38.0% at 2.0 m. Operation at 2.0 Q~2.0 m and 3.0 Q~1.0 m above the sludge rising phenomenon occurred causing adverse effects on the public bodies. If the flow rate increases, the processing efficiency is reduced from 74.2% to 17.3%, even though the sludge interface height was maintained at 0.5 m, so that the inflow adjustment was most important during rainfall, and the interface height of 1.0 m should be maintained to minimize the adverse effect on public water system.

Simultaneous traveltime inversion of surface and borehole seismic data in Pungam basin (풍암분지 시험시추공 주변에서의 지표 및 시추공 초동주시 동시역산)

  • Kim, Ki-Yeong;Hong, Myung-Ho
    • Journal of the Korean Geophysical Society
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    • v.9 no.1
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    • pp.37-45
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    • 2006
  • Velocity structures were defined in the vicinty of the 140-m deep test borehole in the pungam basin through simultaneous inversion of surface seismic refraction and far-ofset VSP traveltime data. Seismicenergy generated at the surface by a seisgun was recorded both at 42 surface locations at 3-m intervalsalong the profiles in the N20E and its orthogonal directions and at 71 m depth in the borehole. Forthe ofset VSP study, seismic energy was generated by a 5 kg sledgehamer at the surface in the horizontal ofset range of -19.5∼+19.5 m from the borehole. The seismic signals were detected at 9∼99 m depths with 1∼2 m intervals and recorded for 204 ms per shot. After shot static corrections,first-arrival times picked from both the surface refraction and borehole records were simultaneouslyinverted to yield velocity tomograms. The tomograms indicate that a 1.5 m thick soil layer with velocities les than 500 m/s overlies basements having a velocity range of 3,067 ∼5,717 m/s. Within the basements,∼4 m and deeper than 71 m. The high-velocit yzones may be due to conglomerates intercalated with sandstones and siltstones. No evidence for large-scale fracture zones or faults is detected near the borehole

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