• 대한핵의학회지
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• 제34권4호
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• pp.336-343
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• 2000

목적: $[^{201}Tl]$TICI주사액의 제조과정에서 안정동위원소인 $^{201}Tl$ 및 Cu, Pb의 중금속을 함유할 가능성이 있어 이러한 이물질을 확인하기 위한 방법으로 방사성 물질의 대기오염을 일으키지 않는 폴라로그래피의 분석 조건을 설정하고자 하였다. 대상 및 방법: 원자력병원에서 생산하고 있는 $[^{201}Tl]$-TlCl 주사액에 포함될 수 있는 중금속을 대상으로 하였다. 극미량의 중금속을 측정하기 위한 방법으로 BAS-50W 폴라로그래피를 이용하였고, 여기에 사용된 3 전극계는 작업전극인 DME, 기준전극인 Ag/AgCl 그리고 보조전극인 백금선을 이용하였다. 신속하고 재현성있는 분석을 위한 조건으로 기기의 분석 모드, 각 모드에 적합한 전극, 지지전해질, 석출시간 등의 치적 조건을 설정하였다. 결과: 폴라로그래피의 모드는 OSWSV 방법이 재현성과 감도면에서 가장 우수하였고, 작업전극은 DME와 Au 전극을 비교 실험한 결과 재현성 면에서 DME가 보다 좋은 결과를 보였다. 지지전해질은 염기성인 0.50 M KOH 용액, 산성인 1.0 M $HNO_3$, 용액, 중 성인 pH 7 phosphate 완충용액을 비교 실험하여 pH 7 phosphate 완충용액이 $Tl^+$과 $Cu^{2+}$를 분석하는데 가장 적합함을 확인하였다. 이를 바탕으로 중금속을 측정한 결과 $Tl^+$은 -450 mV, $Cu^{2+}$는 -50 mV에서 각각의 피크가 나타났고, 석출시간을 45초로 하였을 때 $Tl^+$의 경우 y=2.05E-$9{\chi}$+5.66E-9이고 $Cu^{2+}$의 경우는 y=1.23E-$8{\chi}$+1.23E-6의 선형 관계식을 얻었다. 결론: 이 방법에 의한 Tl과 Cu의 검출한계는 약 0.05 ppm이다. 이 방법을 현재 원자력병원에서 생산하고 있는 $[^{201}Tl]$TICl 주사액의 정도관리에 도입하여 중금속을 측정한 결과 약전에서 규정하고 있는 2 ppm 미만임을 확인하였고, 그 결과는 재현성, 정확도, 감도 및 간편성에서 모두 만족할 수 있었다. 이 방법은 $[^{201}Tl]$TlCl 주사액 뿐만 아니라 $^{67}Ga$ 주사액 및 기타 방사성의약품과 중금속 분석에도 응용할 수 있다.

• Bulletin of the Korean Chemical Society
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• 제35권2호
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• pp.489-493
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• 2014

A phenylbenzimidazole derivatized sensor (L) that behaves as a ratiometric fluorescent receptor for $Zn^{2+}$ in water has been described. In HEPES buffer at pH 7.4, sensor L displays a weak fluorescence emission band at 367 nm. Upon addition of $Zn^{2+}$, the emission intensity at 367 nm is decreased, concomitantly, a new emission band centered at 426 nm is developed, thus facilitates a ratiometric $Zn^{2+}$ sensing behavior. Sensor L binds $Zn^{2+}$ through a 1:1 binding stoichiometry with high selectivity over other metal cations. Sensor L displays a linear response to $Zn^{2+}$ concentration from 0 to $6.0{\times}10^{-5}M$, sensor L also exhibits high sensitivity to $Zn^{2+}$ with a detection limit of $3.31{\times}10^{-7}M$.

• The Plant Pathology Journal
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• 제26권1호
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• pp.63-69
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• 2010

The effect of Acibenzolar-S-methyl (ASM) and Rahnella aquatilis Ra39 against apple fire blight disease caused by Erwinia amylovora were tested as a possible alternative to streptomycin. In vitro studies, no inhibition effect against the pathogen was found when ASM was tested. Under greenhouse conditions, application of R. aquatilis Ra39 with the highly susceptible M26 rootstock resulted in a marked disease suppression. Application of ASM and strain Ra39 caused a high decrease of the disease, 82% and 58% respectively; this was correlated with a reduction of the growth of the pathogen within host plants up to 64% and 49.5% respectively. Further studies in the field under artificial infection condition during full bloom revealed that application of ASM and R. aquatilis Ra39 with Gala variety resulted in a control effect up to 21 and 29% respectively. In physiological studies, enhanced activities of PR-proteins (chitinase and $\beta$-1, 3-glucanase) were detected, which are well known as biochemical markers for systemic acquired resistance. Application of ASM to apple shoots caused the highest chitinase activity followed by strain Ra39. The enzyme activity was increased after 2, 4 and 6 days from application. In addition, ASM-treatment caused the higher $\beta$-1, 3-glucanase activity than strain Ra39. Maximum enzyme activity was recorded after 6 days from application and then decreased after 8 and 10 days from application.

• 센서학회지
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• 제28권1호
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• pp.30-35
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• 2019

Inertial measurement units (IMUs) are widely used for wearable motion-capturing systems in the fields of biomechanics and robotics. When the IMUs are combined with optical motion sensors (hereafter, OPTs) for their complementary capabilities, it is necessary to align the coordinate system orientations between the IMU and OPT. In this study, we compare the application of two coordinate transformation-based orientation alignment methods between two coordinate systems. The first method (M1) applies angular velocity coordinate transformation, while the other method (M2) applies gyroscopic angle coordinate transformation. In M1 and M2, the angular velocities and angles, respectively, are acquired during random movement for a least-square algorithm to determine the alignment matrix between the two coordinate systems. The performance of each method is evaluated under various conditions according to the type of motion during measurement, number of data points, amount of noise, and the alignment matrix. The results show that M1 is free from drift errors, while drift errors are present in most cases where M2 is applied. Thus, this study indicates that M1 has a far superior performance than M2 for the alignment of IMU and OPT coordinate systems for motion analysis.

• 융합신호처리학회논문지
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• 제21권3호
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• pp.142-147
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• 2020

사물인터넷(IoT)은 개인, 공공, 산업 등 국가 사회 현안 해결의 수단으로 활용 가치가 있으며, 특히, 헬스케어산업에 사물인터넷 기술을 적용되고 있다. 사물인터넷 기반 헬스케어 서비스를 위해서는 신뢰성 및 보안성 보장이 중요하며, IoT 헬스케어 디바이스에 적합한 통신 프로토콜, 무선 송수신 기법, 신뢰성 기반 메시지 전달 등의 필요성이 요구된다. 본 논문에서는 oneM2M 기반 헬스케어 서비스 적용 모델을 제안하고 헬스케어 서비스에 적용하기 위해 체온, 가속도 센서를 통해 체온 및 활동량에 대한 상태를 측정하여 oneM2M을 기반으로 개발된 Mobius 플랫폼으로 전달하도록 시스템을 설계하고 구현하였다.

• Journal of Microbiology
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• 제42권3호
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• pp.228-232
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• 2004

In this paper, we investigated the development of a simplified and rapid primary capture step for the recovery of M13 bacteriophage from particulate-containing feedstock. M13 bacteriophage, carrying an insert, was propagated and subsequently purified by the application of both conventional multiple steps and expanded bed anion exchange chromatography. In the conventional method, precipitation was conducted with PEG/NaCl, and centrifugation was also performed. In the single step expanded bed anion exchange adsorption, UpFront FastLine$\_$TM/20 (20mm i.d.) from UpFront Chromatography was used as the contactor, while 54$m\ell$ (H$\_$o/=15cm) of STREAMLINE DEAE (p=1.2 g/㎤) from Amersham Pharmacia Biotechnology was used as the anion exchanger. The performance of the two methods were evaluated, analysed, and compared. It was demonstrated that the purification of the M13 bacteriophage, using expanded bed anion exchange adsorption, yielded the higher recovery percentage, at 82.86％. The conventional multiple step method yielded the lower recovery percentage, 36.07％. The generic application of this integrated technique has also been assessed.

• 대한화학회지
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• 제32권4호
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• pp.323-332
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• 1988

요소는 박테리아가 가지고 있는 urease에 의해 2분자의 $NH_3$와 1분자의 $CO_2$ 기체를 생성한다. Proteus vulgaris를 $NH_3\;와\;CO_2$ 기체 감응전극에 고정시켜 박테리아 전극을 조립하고, pH, 온도, 완충용액, 박테리아(균)의 양 및 여러가지 방해불질의 영향과 전극의 수명등에 관하여 조사하였다. $NH_{3-}$박테리아 전극은 $25^{\circ}C$에서 pH 7.4인 0.05M phosphate완충용액을 사용하였을 때 직선범위는 $7.0{\times}10^{-4}\;-\;3.0{\times}10^{-2}$M 이었고, 감응 기울기는 116.7 mV/decade였다. 한편, $CO_{2-}$박테리아 전극은 $30^{\circ}C$, pH 7.0, 0.1M phosphate완충용액을 사용하였을 때 $7.0{\times}10^{-4}\;-\;5. 0{\times}10^{-2}$M내에서 감응 기울기는 $45.4{\sim}45.7mV/decade$로 나타났다. 실제 임상적인 응용으로서 요속에 들어 있는 요소를 정량하고 분광광도법과 비교하였다. 결과적으로 이 전극의 경우는 실험과정이 간단하고 편리하여 신속하게 많은 양의 시료 분석이 가능하였다.

• 한국지반환경공학회 논문집
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• 제9권5호
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• pp.21-27
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• 2008

퇴사는 하천과 저수지의 기능을 저해하는 주요 요소 중 하나로 취수구 부분의 펌프 임펠러 손상 등 많은 문제점을 내포하고 있다. 따라서 저수지의 운영 및 계획, 수자원의 효율적 활용을 위해서는 정확한 퇴사량 산정이 이루어져야 한다. 본 연구의 목적은 경상북도 운문호 2차원모형(SMS)을 이용한 퇴사량 예측에 있다. 계획홍수위(EL.152.12m)의 저수용량과 비교할 경우 RUSLE모형의 경우 50년 후 $2,084.09{\times}10^6m^3$, 100년 후 $2,196.65{\times}10^6m^3$로 감소하는 것으로 나타났다. 2차원 모형의 경우 50년 후의 저수량은 $2,227.41{\times}10^6m^3$, 100년 후에 저수량은 $2,121.47{\times}10^6m^3$로 감소하는 것으로 나타났다. 적용결과 2차원모형은 저수지 퇴사량 산정에 매우 유용할 것으로 판단된다.

• Restorative Dentistry and Endodontics
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• 제25권3호
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• pp.338-358
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• 2000

The effect of bench drying or removal of the periodontal ligament with NaOCl upon periodontal healing and root resorption after replantation of molars was studied in rats. A total of 40 Sprague-Dawley female rats were used and fed a powdered purina rat chow diet containing 0.4% beta-aminoproprionitrile. The maxillary first molars were extracted and the periodontal ligaments were removed either by bench drying for 15 minutes or by immersion in 2.5% NaOCl solution. The rats were sacrificed at 5, 10, and 21 days by heart infusion. In order to observe the effect of 0.5% stannous fluoride, $10^{-4}M$, $10^{-2}M$, and 1M etidronate disodium on the early stage of periodontal healing, the periodontal ligament was removed with 2.5% NaOCl followed by immersion of the molar in the respective solutions for 5 minutes. The rats were sacrificed after 10 days and the following results were obtained. 1. The removal of the periodontal ligament with 2.5% NaOCl seemed to be more effective than bench drying, since the resorption area in the NaOCl treated group showed a gradual increase whereas a decline in resorption area from 5 days to 21 days was observed in the bench dried group. 2. The application of 0.5% stannous fluoride seemed to enhance the periodontal ligament attachment and active migration of fibroblasts could be observed. 3. The application of $10^{-4}M$, $10^{-2}M$, and 1M etidronate disodium led to a good periodontal ligament attachment. No evident areas of root resorption were found. 4. The use of ${\beta}$-APN made it possible to extract the maxillary first molar with all five roots intact.

• 한국정밀공학회지
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• 제15권2호
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• pp.53-60
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• 1998

In this study, it is experimented to find factors effecting surface roughness using the system of experiments. in the mirror surface finishing system. (1) The film feed and oscillation frequency in $40{\mu}m$ abrasive film, grinding speed in $30{\mu}m$, and machining time in $15{\mu}m$15 are the main factors effecting the surface roughness. (2) Applying the optimal finishing condition to $40{\mu}m$, $30{\mu}m$, $15{\mu}m$ abrasive finishing film in sequence, it is possible to obtian about Ra 10 nm surface roughness on SM45C workpiece. (3) Application of the system of experments to the micro abrasive grain film finishing was very effective method in the extraction of main factor and optimal condition.