• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 하계종합학술대회 논문집(5)
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• pp.81-84
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• 2001

This paper presents a potable bio-signal measurement system using Bluetooth for the 24-hours continuous health state monitoring of the elderly and the disabled. The measurement system has the functions of acquisition of various bio-signals, wireless data transmission and adjustment of parameters such as gain and cut-off frequency. This measurement system is designed according to the international specifications of the recommendation of AAMI (Association for the Advancement of Medical Instrumentation). The design targets of the developing system about volume and power consumption are 20x30x5mm$^3$ and 8mW.

• Environmental Analysis Health and Toxicology
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• 제10권1_2호
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• pp.47-54
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• 1995

To investigate and evaluated the scavenging and antioxidative effects of various flavonoids on paraquat induced toxicity, in vivo and vitro tests of eight flavonoids (catechin, epocatechin, flavone, chrysin, apigenin, quercetin, morin and biochanin A) were carried out. The generation of reactive oxygen substances(ROS) in PMS-NADH system $H_2O_2$ induced hemolysis and lipidperoxidation to blood, NADPH dependent lipidperoxidation to liver and lung microsome by paraquat were studied.The results are summerized as follows; 1) In the concentration ranges from 3.3 to 9.8$\mu$M of catechin,epicatechin, quercetin and biochanin A removed the 50% of DPPH radical scavenging effects. 2) In the concentration ranges from 0.60 to 1.86 mM of catechin, epicatechin, quercetin and biochanin A showed the inhibitory and antioxidative activity on superoxide anion which gernerated in PMA-NADH system. 3) In the concentration ranges from 0.12 to 0.49mM of catechin, epicatechin, quercetin and biochanin A showed the inhibitory and antioxidative activity on H202 which generated in PMA-NADH system. 4) In the concentration ranges from 0.6 x10$^{-5}$ to 6.3 x 10$^{-5}$mM of catechin, epicatechin, flavone, chrysin, quercetin and morin showed the inhibitory and antioxidative activity on $H_2O_2$ induced hemolysis to blood 5) All flavonoids tested exhibited inhibitory and antioxidative effects on paraquat induced liver and tung microsomal lipidperoxidation. Therefore, all flavonoids evaluated showed the useful compounds for scavenger and antioxidant on paraquat induced toxicity.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1999년도 제51차 추계 학술대회 연제집
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• pp.221-223
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• 1999

• Smart Structures and Systems
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• 제5권4호
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• pp.469-482
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• 2009

The emerging sensor-based structural health monitoring (SHM) technology has a potential for cost-effective maintenance of aging civil infrastructure systems. The author proposes to integrate continuous and global monitoring using on-structure sensors with targeted local non-destructive evaluation (NDE). Significant technical challenges arise, however, from the lack of cost-effective sensors for monitoring spatially large structures, as well as reliable methods for interpreting sensor data into structural health conditions. This paper reviews recent efforts and advances made in addressing these challenges, with example sensor hardware and health monitoring software developed in the author's research center. The hardware includes a novel fiber optic accelerometer, a vision-based displacement sensor, a distributed strain sensor, and a microwave imaging NDE device. The health monitoring software includes a number of system identification methods such as the neural networks, extended Kalman filter, and nonlinear damping identificaiton based on structural dynamic response measurement. These methods have been experimentally validated through seismic shaking table tests of a realistic bridge model and tested in a number of instrumented bridges and buildings.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2012년도 춘계학술발표대회
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• pp.840-842
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• 2012

오늘날의 정보통신 환경은 유비쿼터스 IT기술의 시대로 진입하고 있다. 유비쿼터스는 사용자가 컴퓨터나 네트워크를 의식하지 않은 상태에서 시간과 장소에 구애받지 않고 자유롭게 네트워크에 접속 할 수 있는 정보와 환경을 의미한다. u-Health(Ubiquitous-Health)는 의료 및 국민 복지에서 떠오르는 분야이며 기존의 의료서비스와는 달리 사용자가 간편하고 언제 어디서나 사용될 수 있는 시스템이다. 기존 u-Health 시스템은 사용자가 착용한 센서로부터 신체 데이터를 제공받고, 제공 받은 데이터로 사용자가 현재 어떠한 상태인지를 파악한다. 그러나 센서로부터 제공받은 신체데이터는 무선통신으로 인한 데이터의 손실 및 오류가 발생하게 된다. 이러한 단점을 극복하고 정확한 환자의 상태를 판단하기 위한 방법으로 온톨로지 기반의 상황인식을 적용하여 기존의 u-Health 시스템 보다 더욱 신뢰성 있는 u-Health 시스템을 구축하고자 한다.

• 핵의학기술
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• 제12권1호
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• pp.33-38
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• 2008

Purpose: The Gated cardiac blood pool scan is non-invasive method that a quantitative evaluation of left ventricular function. Also this scan have shown the value of radionuclide ejection fraction measurements during the course of chemotherapy as a predictor of cardiac toxicity. Therefore a reliable method of monitoring its cardiotoxic effects is necessary. the purpose of this study is to minimize the overestimate of left ventricular ejection fraction (LVEF) by modified body position to reduce the influence of scattered rays from surrounding organs of the heart in the background region of interest. Materials and Methods: Gated cardiac blood pool scan using in vivo $^{99m}Tc$-red blood cell (RBC) was carried out in 20 patients (mean $44.8{\pm}8.6$ yr) with chemotherapy for a breast carcinoma. Data acquisition requires about 600 seconds and 24 frames of one heart cycle by the multigated acquisition mode, Synchronization deteriorates toward the end of the cycle and with the distance from the trigger signal (R-wave) by ECG gating. Gated cardiac blood pool scan was studied with conventional method (supine position and the detector head in $30-45^{\circ}$ left anterior oblique position and caudal $10-20^{\circ}$ tilt) and compared with modified method (left lateral flexion position with 360 mL of drinking water). LVEF analysis was performed by using the automatically computer mode. Results: The ROI counts of modified scan method were lower than LV conventional method ($1429{\pm}251$ versus $1853{\pm}243$, <0.01). And LVEF of modified method was also decrease compared with conventional method ($58.3{\pm}5.6%$ versus $65.3{\pm}6.1%$, <0.01). Imaging analysis indicated that stomach was expanded because of water and spleen position was changed to lateral inferior compared with conventional method. Conclusion: This study shows that the modified method in MUGA reduce the influence of scattered rays from surrounding organs. Because after change the body position to left lateral flexion and drinking water, the location of spleen, left lobe of liver and stomach had changed and they could escaped from background ROI. Therefore, modified method could help to minimize the overestimate LVEF (%).

• 전자공학회논문지
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• 제50권2호
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• pp.20-26
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• 2013

본 논문에서는 셀룰라시스템이 운용중인 Licensed 주파수 대역에서 M2M 단말간 직접통신을 공존운용하기 위한 PHY 프레임구조를 제안한다. 최근 들어 SmartGrid, Mobile Health, Smart Car를 포함한 M2M(Machine to Machine) 서비스 시장이 빠른 속도로 성장하고 있다. 이러한 M2M 서비스를 Licensed 주파수 대역 기반의 셀룰라시스템을 통해서 제공하는 경우 자원의 낭비를 초래할 수 있다. 일예로, 서로 인접하여 위치하는 시나리오에서는 M2M 단말간 직접통신을 하는 것이 자원 활용 측면에서 효율적이다. 본 논문에서는 기존 셀룰라 통신시스템의 PHY 프레임구조를 변경하지 않는 것을 중요한 요구사항으로 정한다. 이러한 하위호환성 요구사항을 만족시키면서, 기존 셀룰라시스템과 동일한 licensed 주파수 대역에서 공존운용이 가능한 M2M 단말간 직접통신시스템의 PHY 프레임구조를 제안한다. 따라서, 본 논문에서 제안하는 M2M 직접통신을 위한 프레임 구조는 기존 셀룰라시스템과의 호환성을 유지하면서, M2M 단말간 직접통신을 위한 추가적인 주파수 소요 없이 한정된 주파수 자원을 효율적으로 활용할 수 있는 방안이 되리라 예상된다.

• Toxicological Research
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• 제34권4호
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• pp.343-354
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• 2018

Aluminum oxide nanoparticles ($Al_2O_3$ NPs) are among the most widely used nanomaterials; however, relatively little information about their risk identification and assessment is available. In the present study, we aimed to investigate the potential toxicity of $Al_2O_3$ NPs following repeated inhalation exposure in male Sprague-Dawley rats. Rats were exposed to $Al_2O_3$ NPs for 28 days (5 days/week) at doses of 0, 0.2, 1, and $5mg/m^3$ using a nose-only inhalation system. During the experimental period, we evaluated the clinical signs, body weight change, hematological and serum biochemical parameters, necropsy findings, organ weight, and histopathology findings. Additionally, we analyzed the bronchoalveolar lavage fluid (BALF), including differential leukocyte counts, and aluminum contents in the major organs and blood. Aluminum contents were the highest in lung tissues and showed a dose-dependent relationship in the exposure group. Histopathology showed alveolar macrophage accumulation in the lungs of rats in the $5mg/m^3$ group during exposure and recovery. These changes tended to increase at the end of the recovery period. In the BALF analysis, total cell and neutrophil counts and lactate dehydrogenase, tumor necrosis factor-${\alpha}$, and interleukin-6 levels significantly increased in the 1 and $5mg/m^3$ groups during exposure. Under the present experimental conditions, we suggested that the no-observed-adverse-effect level of $Al_2O_3$ NPs in male rats was $1mg/m^3$, and the target organ was the lung.

• Korean Journal of Acupuncture
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• 제28권3호
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• pp.63-71
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• 2011

Objectives : The aim of this study is to develop the system and evaluate the optical analytical technique that reflects acupoint pigmentation and extravasated blood by cupping. Methods : We designed the system able to express XYZ coordinate on local skin color. To evaluate measurement-accuracy, we compared with 24 Color Checker Chart by standardized Commission Internationale de l'Eclairage. After confirming the performance of system, we experimented with cupping which was 80 kPa negative pressure for 1 minute on left/right BL13. The X, Y and Z values were converted to R, G and B, $L^*$, $a^*$ and $b^*$, Erythema Index (E.I.), and Melanin Index (M.I). We compared and analyzed two cases on before/after cupping. Results : The R, G and B values which were converted by X, Y and Z values had high linearity as a high level of R-square (R: 0.969, G: 0.996, and B: 0.992). Moreover, we confirmed that it was possible to quantitatively analyzed the change in skin color by cupping using R, G, B, $L^*$, $a^*$, $b^*$, E.I., and M.I. Conclusions : Therefore, we proposed the new analytical technique for objectifying the oriental medical diagnostic method using cupping and optical sensing technique.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2010년도 하계학술대회 논문집
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• pp.282-282
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• 2010

LED Device was designed of electronic circuits of electrical power part for used Pspice student version and used Infrared LED lamps of load part. LED was used Computerized Electronic Medical Infrared Thermographic Imaging System for body surface Investigation of variable Body thermal asymmetry. It was knowledge body thermal Asymmetry of body surface and quantity body surface of electromagnetic wave to inflow electrical power part.