• The Plant Pathology Journal
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• 제26권2호
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• pp.198-202
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• 2010

A study was conducted to find out the relationship of physico-chemical properties (viz. organic carbon(OC), pH, electrical conductivity, nitrogen, phosphorus and potassium content) of ginger growing soil with incidence percentage of rhizome rot and wilt disease complex of ginger. Organic carbon content and pH of the ginger soil contributed significantly (93%) in the prediction of ginger rhizome rot and wilt disease complex incidence with negative correlation. Soil having weak acidic reaction with OC percent greater than 2.25 was observed to have the lower average incidence of the disease.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2002년도 Proceedings of International Symposium on Remote Sensing
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• pp.208-208
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• 2002

Relationship between chlorophyll a in the East China Sea and spectral bands (412, 443,490, (510), 555, (676,765) in) of OSMI (Ocean Scanning Multi-Spectral Imager) including the profile multi-spectral radiometer (PRR-800) was studied. The values of remote sensing reflectance (Rrs) at the bands corresponding to the field chlorophyll a in α in the East China Sea were much higher than those in clear waters off California, USA. In case of the particle absorptions related to the chlorophyll a concentration at the spectral bands (440, 670 nm) were much higher in the East China Sea than the ones in the clean waters off California. The normalized water leaving radiances (nLw) at 412, 443, 490, 555 m of OSMI and field chlorophyll a in the East China Sea were correlated each other. According to the results, the relationship between field chlorophyll a and nLw 410 m in OSMI bands was the lowest, whereas that between the field chlorophyll a and nLw 555 nm in the bands was the highest. Reciprocal action between the field chlorophyll a and the band ratio of the OSMI bands (nLw410/nLw555, nLw443/nLw555, nLw490/nLw555) was also studied. Correlation between the chlorophyll a and the band ratio (nLw490/nLw555) was highest in the OSMI bands. Relationship between the chlorophyll a and the ratio (nLw443/nLw555) was higher than one in the nLw410/nLw555. The difference in the estimated chlorophyll α (mg/m3) between OSMI and SeaWiFS (Sea Viewing Wide Field-of-View Sensor) at the special observing stations in the northern eastern sea of Jeju Island in february 25, 2002 was about less than 0.3 mg/m3 within 3 hours. It is suggested that OC2 (ocean color chlorophyll 2 algorithm) be used to get much better estimation of chlorophyll α from OSMI than the ones from the updated algorithms as OC4.

• Nutrition Research and Practice
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• 제5권5호
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• pp.464-470
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• 2011

Growing evidence suggests an elevated risk for colorectal neoplasia among individuals with low levels of vitamin D, the biological actions of which are mediated by the vitamin D receptor (VDR). To investigate the association among vitamin D status, VDR polymorphisms (FokI, and BsmI), and colorectal adenoma, we conducted a meta-analysis of nine studies of circulating levels of 25-hydroxyvitamin D (25(OH)D) and five studies of FokI or BsmI polymorphisms in relation to colorectal adenomas. Study-specific relative risks (RRs) and 95% confidence intervals (CIs) were pooled using a random-effects model. A total of 3398 coloreetal adenomas for 25(OH)D and 1754 colorectal adenomas for VDR were included in the meta-analysis. We identified a significant inverse association between colorectal adenoma (combined RR, 0.93; 95% CI, 0.87-0.98 per 10 ng/mL increase in 25(OH)D levels). When we examined FokI and BsmI polymorphisms in the meta-analysis, we found no association for either FokI (combined RR, 1.00; 95% CI, 0.95-1.06) or BsmI (combined RR, 0.99; 95% CI, 0.93-1.05) in the additive model. These data suggest an inverse association between circulating 25(OH)D levels and colorectal adenoma risk.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4481-4485
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• 2012

Background: Chemotherapy induced leutropenia has been shown to be associated with improved treatment outcomes in selected solid tumors. We studied the association of chemotherapy induced leutropenia with treatment related outcomes in advanced non-small-cell lung cancer. Methods: This is a prospective analysis of patients receiving chemotherapy for advanced NSCLC at the Shandong Cancer Hospital from 2005-07.The chemotherapy included cisplatin $35mg/m^2$, IV on $d_{1,2}$ and vinorelbine $25mg/m^2$ IV on $d_{1,8}$ every 21 days. Patients were stratified into three groups (A) those experiencing grades 0 leucopenia, group (B) grades 1-2 and group (C) grades 3-4. The outcomes studied were response rate (RR), disease control rate (DCR), and time to progression (TTP). Results: 128 patients were studied. The RRs in groups A, B and C were 30.8%, 56.8% and 71.4%, respectively, p=0.010. The DCRs were 61.5%, 83.8% and 92.9%, respectively, p=0.009 and the median TTPs were 150 days (95%CI: 91-209), 189 days (95%CI: 181-197) and 207 days (95%CI: 172-242), p=0.009. The differences in RR and TTP were significant. In patients whose CIL kept on 10 days at least, the TTP was significantly prolonged, p=0.0213, and the same was the case for those experiencing grades 1-2 leucopenia and ECOG 0, p=0.0412. Conclusions: Occurrence of CIL correlated with RR and TTP in patients with advanced NSCLC receiving cisplatin and vinorelbine chemotherapy, especially in patients experiencing grades 1-2 leucopenia and ECOG 0, and the same for those with CIL persisting for 10 days at least. CIL could be a biological measure of drug activity and a marker of efficacy.

• 한국환경보건학회지
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• 제34권2호
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• pp.124-130
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• 2008

This study investigated the age dependencies in ambient air pollution-associated asthma hospitalization from 2003 to 2005 in Seoul. For all ages and the age groups of 0-14, 15-64, and 65+years, the Generalized Additive Model (GAM) was used to estimate the relative risks of daily asthma hospitalization associated with changes in particulate matter and ozone. The time-trends, seasonal variances, day effects, temperature, humidity, and pressure at sea level were controlled in the models. Significant associations were observed between asthma hospitalization and the levels of $PM_{10}$ and $O_3$. The relative risks (RRs) of asthma hospitalization for every 10 unit increases in $PM_{10}({\mu}g/m^3)$ and $O_3$(ppb) were 1.008 (95% CI 1.005-1.012), and 1.012 (95% CI 1.003-1.020), respectively. Evaluated over $10\;{\mu}g/m^3$ increase in $PM_{10}$, we found the relative risks of asthma hospitalization to be 1.009 (95% CI 1.004-1.014) in 0-14 age group, and 1.015 (95% CI 1.008-1.022) in 65+ age group. Considering 10 ppb increase in $O_3$, those were 1.014 (95% CI 1.003-1.024) in 0-14 age group, and 1.025 (95% CI 1.009-1.041) in 65+ age group. It was concluded that current levels of ambient air pollution in Seoul make a significant contribution to the variation in daily asthma hospitalization. Further reduction in air pollution is necessary to protect the health of the community, especially that of the higher risky groups including children and elderly population.

• 한국환경보건학회지
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• 제35권1호
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• pp.1-10
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• 2009

This study assessed the relationships between levels of $PM_{10}$ and hospitalization rates for asthma among children from 2003 to 2005 at four major cities in Korea. In addition, we estimated the reduced number of asthma hospitalization associated with an ambient $PM_{10}$ improvement to the acceptable levels as recommended by the World Health Organization (WHO). The Generalized Additive Model (GAM) was used to estimate the relative risks (RR) of asthma hospitalization associated with changes in $PM_{10}$ The RRs of children's asthma hospitalization for every $10{\mu}g/m^3$ increment in $PM_{10}$ were 1.009(95% CI = 1.004-1.014) in Seoul, 1.013(95% CI = 1.006-1.021) in Incheon, 1.009(95% CI = 1.002-1.016) in Busan, and 1.021(95% CI = 1.005-1.037) in Ulsan. We assessed $PM_{10}$ related health benefits from implementing the WHO's guidelines (24-hour average $50{\mu}g/m^3$) using the U.S. Environmental Protection Agency's Environmental Benefits Mapping and Analysis Program. The estimated benefits were 439(95% CI = 216-666) reduced asthma hospitalization in Seoul, 720(95% CI = 304-1,151) in Incheon, 260(95% CI = 66-459) in Busan, and 126(95% CI = 30-228) in Ulsan. It was concluded that improving $PM_{10}$ condition to the WHO guideline would make a significant contribution to the reduction in asthma hospitalization among children. Therefore, public health measures are still needed to improve air quality in Korea.

• 대한원격탐사학회지
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• 제18권4호
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• pp.187-199
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• 2002

해수광 특성이 시공간적으로 심하게 변동하는 동중국해 북부해역에서 현장 클로로필 $\alpha$와 OSMI 밴드(412, 443, 490, 555nm) 및 해수 다중 광측정기(PRR-800) 밴드(412, 443, 490, 510, 555, 670, 765nm)간의 관계성을 구한 결과, 클로로필 $\alpha$에 대한 각 밴드별 remote sensing reflectance (Rrs) 값이 맑은 해수(미국 캘리포니아 근해)에서 보다 동중국해 북부해역에서 크게 나타났다. 또한 440nm와 670nm 영역에서 현장 관측 클로로필 $\alpha$에 대한 입자 물질들의 광흡수 값이 맑은 해수의 경우보다 큰 값을 보였다. 그러므로, OSMI밴드에서 클로로필로 인해 최대 흡수가 일어나는 밴드가 443nm을 추정할 수 있었다. 동중국해를 관측한 OSMI 위성의 각 band (412, 443, 490, 555 nm)로부터 nLw (normalized water-leaving radiance)와 현장 클로로필 $\alpha$(Chl $\alpha$)값의 관계성(Chl $\alpha$= f(nLw)을 구하였다. OSMI 밴드에서 클로로필 $\alpha$ 값과 각 밴드별 nLw 값과의 상관성은 412nm에서 최저 상관성을, 555nm에서 최고 상관성을 나타내었다. 클로로필 $\alpha$ 현장 관측 값 및 OSMI 복합밴드 비 값(nLw412/nLw555, nLw443/nLw555, nLw490/nLw555)을 비교 분석한 결과, nLw490/nLw555 비 값과 현장 클로로필 $\alpha$ 값간에 최고 높은 상관성을 나타내었다. 다음으로 nLw443/nLw555 순으로 안정된 값을 보였으나, nLw412/nLw555와 클로로필 $\alpha$ 값간의 상관성이 가장 낮게 나타났다. 3시간이내 현장 측정 클로로필 $\alpha$ 값을 기준으로 OSMI 및 SeaWiFS 위성 자료를 OC2 알고리즘을 이용하여 추정한 클로로필 값간의 차이는 해양의 수평 공간 변동에 관계없이 OSMI 추정 값이 약 0.3mg/m$^3$ 정도 일정하게 낮게 나타났다. 향후 OSMI 위성 밴드를 이용한 클로로필 $\alpha$ 추정시에는 SeaWiFS 위성과 관련된 global algorithms 중에서 490nm와 555nm의 복합밴드를 포함하는 OC2 알고리즘(ocean color chlorophyll 2 algorithm)을 사용하는 것이 OC2 series 및 OC4 알고리즘보다 좋은 추정 값을 도출할 수 있을 것으로 기대된다.

• Asian-Australasian Journal of Animal Sciences
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• 제18권1호
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• pp.8-12
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• 2005

Response in a modified reciprocal recurrent selection scheme for egg production was evaluated considering variable family sizes and genetic correlation between purebred and crossbred half sisters. The criteria of selection of purebred breeders included pullet's own performance, purebred full and half sisters and crossbred half sister's performance. Heritability of egg production of crossbreds (aggregate genotype) and purebred's was assumed to be 0.2 and genetic correlation between purebred and crossbred half sisters ($r_{pc}$) as 0.1, 0.2, 0.3, 0.4, 0.5, 1.0, -0.1, -0.2, -0.3, -0.4, -0.5 and -1.0. Number of dams per sire to produce purebred and crossbred progenies assumed to be 5, 6, 7, 8, while number of purebred female progeny ($N_p$) and crossbred progeny ($N_c$) per dam were considered to be 3, 4, 5 and 6 in each case. Considering phenotypic variance as unity, selection indices were constructed for different combinations of dams and progeny for each value of $r_{pc}$. Following selection index theory, response in crossbred and purebred for egg production was computed. Results indicated that response in crossbreds depended mainly on crossbred family size and also on magnitude of$r_{pc}$ irrespective of its direction, and response was greater with large crossbred family size than the purebred families. Correlated response in purebreds depends both on magnitude and direction of $r_{pc}$ and was expected to be greater with large purebred family size only. Inclusion of purebred information increased the accuracy of selection for crossbred response for higher magnitude of$r_{pc}$ irrespective of its direction. Present results indicate that desirable response in both crossbred and purebred performance is a function of $r_{pc}$ and family sizes. The ratio of crossbred and purebred family sizes can be optimized depending on the objective of improving the performance of crossbreds and/or of purebreds.

• Tuberculosis and Respiratory Diseases
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• 제72권1호
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• pp.44-49
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• 2012

Background: Multidrug-resistant tuberculosis (MDR-TB) is an increasing public health problem and poses a serious threat to global TB control. Fluoroquinolone (FQ) and aminoglycoside (AG) are essential anti-TB drugs for MDR-TB treatment. REBA MTB-FQ$^{(R)}$ and REBA MTB-KM$^{(R)}$ (M&D, Wonju, Korea) were evaluated for rapid detection of FQ and kanamycin (KM) resistance in MDR-TB clinical isolates. Methods: M. tuberculosis (n=67) were isolated and cultured from the sputum samples of MDR-TB patients for extracting DNA of the bacilli. Mutations in genes, gyrA and rrs, that have been known to be associated with resistance to FQ and KM were analyzed using both REBA MTB-FQ$^{(R)}$ and REBA MTB-KM$^{(R)}$, respectively. The isolates were also utilized for a conventional phenotypic drug susceptibility test (DST) as the gold standard of FQ and KM resistance. The molecular and phenotypic DST results were compared. Results: Sensitivity and specificity of REBA MTB-FQ$^{(R)}$ were 77 and 100%, respectively. Positive predictive value and negative predictive value of the assay were 100 and 95%, respectively, for FQ resistance. Sensitivity, specificity, positive predictive value and negative predictive value of REBA MTB-KM$^{(R)}$ for detecting KM resistance were 66%, 94%, 70%, and 95%, respectively. Conclusion: REBA MTB-FQ$^{(R)}$ and REBA MTB-KM$^{(R)}$ evaluated in this study showed excellent specificities as 100 and 94%, respectively. However, sensitivities of the assays were low. It is essential to increase sensitivity of the rapid drug resistance assays for appropriate MDR-TB treatment, suggesting further investigation to detect new or other mutation sites of the associated genes in M. tuberculosis is required.