• Title/Summary/Keyword: M-PAM

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Cytotoxicity of Paraquat or Bentazone and Compensatory Effects of 3-Methylcholanthrene on the Rat Liver (Paraquat 및 Bentazone의 세포독성과 흰쥐 간에서 3-Methylcholanchrene의 독성경감효과)

  • Rim, Yo-Sup;Han, Du-Seok
    • Korean Journal of Environmental Agriculture
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    • v.20 no.3
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    • pp.155-161
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    • 2001
  • This study was carried out to investigate cytotoxicity of paraquat or bentazone on NIH 3T3 fibroblasts, toxicity of paraquat or bentazone, and compensatory effects of 3-Methylcholanthrene(3-MC) on the rat liver. In order to MTT assay, the $5.0{\times}10^4$ cell/mL of NIH 3T3 fibroblast in each well of 24 multidish were cultured. After 24 hours, the cells were treated with solution of paraquat or bentazone(1, 25, 50, 100 ${\mu}M$ respectively). After the NIH 3T3 fibroblast of all groups were cultured in same condition for 48 hours. MTT assay were performed to evaluate the cytotoxicity of cell organelles. Paraquat or bentazone $MTT_{50}$ were 1668.97 ${\mu}M$ and 1506.97 ${\mu}M$, respectively. These $IC_{50}$ of paraquat or bentazone were decided low cytotoxicity by Borenfreund. In order to observe the toxicity and compensatory effects of paraquat or bentazone on the rat liver, Sprague-Dawley male rats were used as experimental animals and divided into paraquat or bentazone only treated group and simultaneous application group of paraquat or bentazone and 3-MC. At 30 min and 1, 3, 6, 12, 24, 48 and 96 hrs interval after each treatment, the animals were sacrificed by decapitation and liver were immediately removed, immersed in fixatives, and processed with routine method for light microscopic study. Paraffin sections were stained with H-E, PAM and Best Carmine. Under the light microscope, degenerative changes of hepatic lobules were frequently observed in portal area from 3 hrs after paraquat or bentazone treatment. All hepatic cells were induced degenerative change at 12 hrs and more severe degenerative change at 48 hrs after paraquat or bentazone treatment. Especially, hepatic cells of bentazone only treated group were distinctly showed pyknotic. Glycogen granules were increased in portal area at 3 hrs, all hepatic cells at 12 hrs and remarkably increased at 48 hrs after paraquat or bentazone treated group. But hepatic cells of bentazone only treated group were regeneration at 48 hrs from portal area and glycogen granules of hepatic cells of paraquat or bentazone and 3-MC combination treated group showed in central area only at 48 hrs. The results indicate that 3-MC may be decrease paraquat or bentazone cytotoxicity on the rat liver.

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Signal-Characteristic Analysis with Respect to Backing Material of PVDF-Based High-Frequency Ultrasound for Photoacoustic Microscopy (광음향 현미경을 위한 PVDF 기반 고주파수 초음파 변환기의 흡음층 소재에 따른 신호 특성 분석)

  • Lee, Junsu;Chang, Jin Ho
    • Journal of the Korean Society for Nondestructive Testing
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    • v.35 no.2
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    • pp.112-119
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    • 2015
  • Photoacoustic microscopy is capable of providing high-resolution molecular images, and its spatial resolution is typically determined by ultrasonic transducers used to receive the photoacoustic signals. Therefore, ultrasonic transducers for photoacoustic microscopy (PAM) should have a high operating frequency, broad bandwidth, and high signal-reception efficiency. Polyvinylidene fluoride (PVDF) is a suitable material. To take full advantage of this material, the selection of the backing material is crucial, as it influences the center frequency and bandwidth of the transducer. Therefore, we experimentally determined the most suitable backing material among EPO-TEK 301, E-Solder 3022, and RTV. For this, three PVDF high-frequency single-element transducers were fabricated with each backing material. The center frequency and -6 dB bandwidth of each transducer were ascertained by a pulse-echo test. The spatial resolution of each transducer was examined using wire-target images. The experimental results indicated that EPO-TEK 301 is the most suitable backing material for a PAM transducer. This material provides the highest signal magnitude and a reasonable bandwidth because a large portion of the energy propagates toward the front medium, and the PVDF resonates in the half-wave mode.

Biodegradable Check Dam and Synthetic Polymer, its Experimental Evaluation for Turbidity Control of Agricultural Drainage Water

  • Kim, Minyoung;Kim, Seounghee;Kim, Jinoh;Lee, Sangbong;Kim, Youngjin;Cho, Yongho
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.6
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    • pp.458-462
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    • 2013
  • A drainage ditch is normally a component of drainage networks in farming systems to remove surplus water, but at the same time, it may act as a major conduit of agricultural nonpoint source pollutions such as sediment, nitrogen, phosphorus, and so on. The hybrid turbidity reduction system using biodegradable check dam and synthetic polymer was developed in this study to manage pollutant discharge from agricultural farmlands during rainfall events and/or irrigation periods. The performance of this hybrid system was assessed using a laboratory open channel sized in 10m-length and 0.2m-width. Various check dams using agricultural byproducts (e.g., rice straw, rice husks, coconut fiber and a mixture of rice husks and coconut fiber) were tested and additional physical factors (e.g., channel slope, flowrate, PAM dosage, turbidity level, etc.) affecting on turbidity reduction were applied to assess their performance. A series of lab experiments clearly showed that the hybrid turbidity reduction system could play a significant role as a supplementary of Best Management Practice (BMP). Moreover, the findings of this study could facilitate to develop an advanced BMP for minimizing nonpoint source pollution from agricultural farmlands and ultimately to achieve the sustainable agriculture.

SOUND SIMILARITY JUDGMENTS AND PHONOLOGICAL UNITS

  • Yoon, Yeo-Bom
    • Proceedings of the KSPS conference
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    • 1997.07a
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    • pp.142-143
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    • 1997
  • The purpose of this paper is to assess the psychological status of the phoneme, syllable, and various postulated subsyllabic units in Korean by applying the Sound Similarity Judgment (SSJ) task, to compare the results with those in English, and to discuss the advantage and disadvantage of the SSJ task as a tool for linguistic research. In Experiment 1, 30 subjects listened to pairs of 56 eve words which were systematically varied from 'totally different' (e.g., pan-met) to 'identical' (e.g., pan-pan). Subjects were then asked to rate sound similarity of each pair on a 10-point scale. Not very surprisingly, there was a strong correlation between the number of phonemic segments matched and the similarity score provided by the subjects. This result was in accord with the previous results from English (e.g., Vitz & Winkler, 1973; Derwing & Nearey, 1986) and supported the assumption that the phoneme is the basic phonological unit in Korean and English. However, there were sharply contrasting results between the two languages. When the pairs shared two phonemes (e.g., pan-pat; pan-pen; pan-man), the pairs sharing the fIrst two phonemes were judged significantly more similar than the other two types of pairs. Quite to the contrary, in the comparable English experiments, the pairs sharing the last two phonemes were judged significantly more similar than the other two types of pairs. Experiment 2 was designed to conflrm the results of Experiment 1 by controlling the 'degree' of similarity between phonemes. For example, the pair pan-pam can be judged more similar than the pair pan-nan, although both pairs share the same number of phonemes. This could be interpreted either as confirming the result of Experiment 1 or as the fact that /n/ is more similar to /m/ than /p/ is to /n/ in terms of shared number of distinctive features. The results of Experiment 2 supported the former interpretation. Thus, the results of both experiments clearly showed that, although the 'number' of matched phonemes is the important predictor in judging sound similarity of monosyllabic pairs of both languages, the 'position' of the matched phonemes exerts a different influence in judging sound similarity in the two languages. This contrasting set of results may provide interesting implications for the internal structure of the syllable in the two languages.

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Hydrophilization of hydrophobic membrane surfaces for the enhancement of water flux via adsorption of water-soluble polymers

  • Kim, Ka Young;Rhim, Ji Won
    • Membrane and Water Treatment
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    • v.7 no.2
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    • pp.101-113
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    • 2016
  • In this study, to improve the water flux of porous hydrophobic membranes, various water-soluble polymers including neutral, cationic and anionic polymers were adsorbed using 'salting-out' method. The adsorbed hydrophobic membrane surfaces were characterized mainly via the measurements of contact angles and scanning electron microscopy (SEM) images. To enhance the durability of the modified membranes, the water-soluble polymers such poly(vinyl alcohol) (PVA) were crosslinked with glutaraldehyde (GA) and found to be resistant for more than 2 months in vigorously stirred water. The water flux was much more increased when the ionic polymers used as the coating materials rather than the neutral polymer and in this case, about 70% of $0.31L/m^2{\cdot}h$ (LMH) to 0.50 LMH was increased when 300 mg/L of polyacrylamide (PAAm) was used as the coating agents. Among the cationic coating polymers such as poly(styrene sulfonic acid-co-maleic acid) (PSSA_MA), poly(acrylic acid-comaleic acid) (PAM) and poly(acrylic acid) (PAA), PSSA_MA was found to be the best in terms of contact angle and water flux. In the case of PSSA_MA, the water flux was enhanced about 80%. The low concentration of the coating solution was better to hydrophilize while the high concentration inclined to block the pores on the membrane surfaces. The best coating condition was found: (1) coating concentration 150 to 300 mg/L, (2) ionic strength 0.15, (3) coating time 20 min.

Analysis of Springback and Die Material Suitability in the UHSS Sheet Forming Process (초고강도 강판 성형 시의 스프링백 해석 및 금형 소재 적합성 검토)

  • Oh, I.S.;Yun, D.Y.;Cho, J.H.;Lee, M.G.;Kim, H.Y.;Kim, H.J.
    • Transactions of Materials Processing
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    • v.29 no.4
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    • pp.203-210
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    • 2020
  • In this study, formability and springback behavior of 1.5 GPa grade ultra-high strength steel (UHSS) sheet were predicted through the finite element simulation, and structural stability of the forming dies was verified by the coupled forming-structural analysis. Uniaxial tension and uniaxial tension-compression tests were performed to obtain experimental data for modeling the springback properties of the sheet material. The springback values predicted by simulation were compared with those from actual measurements. The results calculated from the kinematic hardening model were found to be much more accurate than those from the isotropic hardening model. Deformation of the forming die and springback of the product were calculated by the coupled forming-structural analysis. The higher the strength of the die material, the smaller the surface displacement of the die and the springback of the product. The internal stresses of the dies made of three materials, FC300, FCD550 and STD11 were compared with the yield stress of each material. The results provided a basis for determining the most suitable material for each part of the die set. As a result, simulation techniques have been established for predicting formability and springback in the UHSS sheet forming process.

The Effect of Intradermal Acupuncture Therapy at Kyeonjeong, Cheonryo and Kokji on the Shoulder Pain (견정(肩井), 천요(天?), 곡지(曲池)의 피내침 요법이 견통(肩痛)에 미치는 효과)

  • Yoon, Hyun-Min;Kim, Jong-Hee;Lee, Ji-Won
    • Journal of Acupuncture Research
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    • v.23 no.5
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    • pp.155-165
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    • 2006
  • Objectives : This study was to examine the effect of Intradermal Acupuncture therapy at Kyeonjeong, Cheonryo and Kokji on the shoulder pain. The research was conducted with non equivalent control group non-synchronized design. Methods : IThe subjects were the women who was suffering for shoulder pain, who are employed at two hospitals in Busan, from April to June, 2006. The 24 women were experimental group who were applied to Intradermal Acupuncture Therapy at Kyeonjeong, Cheonryo and Kokji, while the 20 women were control group who weren't applied to any treatments. The severity of shoulder pain and the extent of the subjective symptoms of shoulder pain were pre-measured. The Intradermal Acupuncture therapy was done a total of 4 times, 2 times a week over 2 weeks and from 11 a.m. to 2 p.m. as an experimental treatment. As a post survey, the severity of shoulder pain, the frequency of shoulder pain and the extent of the subjective symptoms of shoulder pain were measured after one week and two weeks of experimental treatment. Research tools are Visual Analogue Scale by Cline et al. for measuring the severity of shoulder pain and the tool developed by Japan's industrial fatigue research committee of the industrial hygienics society and modified. Results : There was a significant difference(F=4.132, p=0.019) for the severity of shoulder pain on the interaction between time and group. There was a significant difference(F=11.193, p=0.000) for the extent of the subjective symptoms of shoulder pain on the interaction between time and. group. Conclusion : Based on the above results, it can be determined that Intradermal Acupuncture Therapy at Kyeonjeong, Cheonryo and Kokji can be used as the effective treatments for reducing of shoulder pam.

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Characterization of a New Poly(acrylonitrile-itaconate) based Gel-electrolyte (새로운 poly(acrylonitrile-itaconate)공중합체를 기초로 한 젤-전해질의 특성)

  • Choi B. K.;Kim S. H.;Gong M. S.
    • Journal of the Korean Electrochemical Society
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    • v.3 no.3
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    • pp.169-172
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    • 2000
  • A new gel polymer electrolyte based on the modified polyacrylonitrile (PAN), polyacrylonitrile-co-bis[2-(2-methoxyethoxy)ethyl]itaconate (abbreviated as PANI) copolymer was synthesized in expectation of enhanced trapping ability of liquid electrolytes. PAN and PANI blend was complexed with organic solvents, ethylene carbonate (EC) and dimethyl carbonate (DMC), and $LiClO_4$ salt. The highest room temperature conductivity of $2\times10^{-3}\;Scm^{-1}$ was found for a film of 25PAN+10PANl+50EC/DMC+$15LiClO_4$. The solvent-rich crystalline part decreases due to the blending of PANI and therefore number of charge carriers increases giving higher ionic conductivity. The addition of PAM as a host polymer in the PAN-based gels has beneficial effects such as higher ionic conductivity, better thermal characteristics, better miscibility with solvent, wider electrochemical stability, and better interfacial stability with lithium electrode, though it exhibits slightly less mechanical rigidity.

VIRTUAL PREDICTION OF A RADIAL-PLY TIRE'S IN-PLANE FREE VIBRATION MODES TRANSMISSIBILITY

  • CHANG Y. P.;EL-GINDY M.
    • International Journal of Automotive Technology
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    • v.6 no.2
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    • pp.149-159
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    • 2005
  • A full nonlinear finite element P185/70Rl4 passenger car radial-ply tire model was developed and run on a 1.7-meter-diameter spinning test drum/cleat model at a constant speed of 50 km/h in order to investigate the tire transient response characteristics, i.e. the tire in-plane free vibration modes transmissibility. The virtual tire/drum finite element model was constructed and tested using the nonlinear finite element analysis software, PAM-SHOCK, a nonlinear finite element analysis code. The tire model was constructed in extreme detail with three-dimensional solid, layered membrane, and beam finite elements, incorporating over 18,000 nodes and 24 different types of materials. The reaction forces of the tire axle in vertical (Z axis) and longitudinal (X axis) directions were recorded when the tire rolled over a cleat on the drum, and then the FFT algorithm was applied to examine the transient response information in the frequency domain. The result showed that this PI 85/70Rl4 tire has clear peaks of 84 and 45 Hz transmissibility in the vertical and longitudinal directions. This result was validated against more than 10 previous studies by either theoretical or experimental approaches and showed excellent agreement. The tire's post-impact response was also investigated to verify the numerical convergence and computational stability of this FEA tire model and simulation strategy, the extraordinarily stable scenario was confirmed. The tire in-plane free vibration modes transmissibility was successfully detected. This approach was never before attempted in investigations of tire in-plane free vibration modes transmission phenomena; this work is believed to be the first of its kind.

A Review on Multidecadal Coastal Changes at Funafuti, Tuvalu from 1897 to 2015

  • Ahmed, Harun-Al-Rashid;Chan-Su, Yang
    • Korean Journal of Remote Sensing
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    • v.39 no.1
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    • pp.23-45
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    • 2023
  • Tuvalu is a small reef islands country in the Pacific Ocean. Its coastal regions are very much dynamic due to the profound effects of tropical cyclones and sea level rise (SLR). However, research works on coastline dynamics of Tuvalu mainly cover its capital, Funafuti. Therefore, this review summarizes the extent of long-term coastal changes in different islets of Funafuti and on overall Tuvalu. In Funafuti, highly accreting areas are Te Afualiku, Fuafatu, Motugie, and Amatuku, and highly eroding areas are Fuagea and Tefala with the fully disappeared islet of Vasafua after 2005. However, in spite of different causes and supposition of scientists on disappearing these lands the accretion is more dominant than erosion which resulted in 7.3% net increase of land areas of Tuvalu over 117 years till 2015. Severe tropical cyclones mainly caused accretion of land areas by forming coral rubble rampart formation and further reworks and erosion to small sandy islands whereas frequent low-energy cyclones mainly caused erosion. Though, till now severe erosion of coastal areas are not evident by global SLR, islets of Funafuti experienced remarkable shoreline increase as formation of 30-40 m wide rubble rampart formation along 19 km in 1971 by tropical cyclone Bebe and net increase of area of 3.45 ha by tropical cyclone Pam in 2015. In spite of such overall accretion of coastal areas several scientists suspect drowning of its areas in future because of high SLR (~5.1±0.7 mm/year) at Funafuti which supposedly will not work as a breakwater anymore. Thus, protection measures should be taken to prevent coastline erosion as well as land reclamation activities should be done following the global examples.