• The Korean Journal of Nuclear Medicine
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• v.36 no.5
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• pp.288-297
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• 2002

Purpose: Soft tissue attenuation and scattering are major methodological limitations of myocardial perfusion SPECT. To overcome these limitations, algorithms for attenuation, scatter correction and resolution recovery (ASCRR) is being developed, while quantitative myocardial SPECT has also become available. In this study, we investigated the efficacy of an ASCRR-corrected quantitative myocardial SPECT method for the diagnosis of coronary artery disease (CAD). Materials and Methods: Seventy-five patients (M:F=51:24, $61.0{\pm}8.9$ years old) suspected of CAD who underwent coronary angiography (CAG) within $7{\pm}12$ days of SPECT(Group-I) and 20 subjects (M:F=10:10, age $40.6{\pm}9.4$) with a low likelihood of coronary artery disease (Group-II) were enrolled. Tl-201 rest/ dipyridamole-stress Tc-99m-MIBI gated myocardial SPECT was performed. ASCRR correction was peformed using a Gd-153 line source and automatic software (Vantage-Pro; ADAC Labs, USA). Using a 20-segment model, segmental perfusion was automatically quantified on both the ASCRR-corrected and uncorrected images using an automatic quantifying software (AutoQUANT; ADAC Labs.). Using these quantified values, CAD was diagnosed in each of the 3 coronary arterial territories. The diagnostic performance of ASCRR-corrected SPECT was compared with that of non-corrected SPECT. Results: Among the 75 patients of Group-I, 9 patients had normal CAG while the remaining 66 patients had 155 arterial lesions; 61 left anterior descending (LAD), 48 left circumflex (LCX) and 46 right coronary (RCA) arterial lesions. For the LAD and LCX lesions, there was no significant difference in diagnostic performance. In Group-II patients, the overall normalcy rate improved but this improvement was not statistically significant (p=0.07). However, for RCA lesions, specificity improved significantly but sensitivity worsened significantly with ASCRR correction (both p<0.05). Overall accuracy was the same. Conclusion: The ASCRR correction did not improve diagnostic performance significantly although the diagnostic specificity for RCA lesions improved on quantitative myocardial SPECT. The clinical application of the ASC-RR correction requires more discretion regarding cost and efficacy.

• Journal of Embryo Transfer
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• v.22 no.3
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• pp.179-184
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• 2007

Culture method of somatic cells is one of the important factors in the production of transgenic pigs by somatic cell nuclear transfer. In this study, we established an efficient culture method of porcine fetal fibroblasts. Porcine fetal fibroblasts were isolated from 33-day-old fetuses. The proliferation of porcine fetal fibroblasts was analyzed by different serum types and culture media. The cultures in medium supplied 15% ES screened FBS showed faster increase in cell number than 15% FBS. Also, fetal fibroblasts have been propagated continuously for $7{\sim}8$ passages in ES modified DMEM and DMEM medium. We transfected $PGK-neo^r$ vector (pKJ2) into porcine fetal fibroblasts to estimate colony formation in this culture condition. The formation of colonies was confirmed in the medium containing $300\;{\mu}g/ml$ G418 at 12 day. These data show that this culture system can be used screening of porcine somatic cells transfected transgene.

• The Korean Journal of Nuclear Medicine Technology
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• v.15 no.1
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• pp.86-89
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• 2011

Purpose: The KOTRON-13 cyclotron was developed in South Korea and was introduced to regional cyclotron centers to produce short-lifetime medical radioisotopes. However, this cyclotron has limited capacity to produce carbon-11 isotope so far. We herein study how to develop and optimize an effective carbon-11 target system in the KOTRON-13 cyclotron by changing cooling system, combing with fluorine-18 target and evaluating beam currents. Materials and Method: To develop the optimal carbon-11 target and an effective cooling system, we designed the carbon-11 target system by Stopping and Range of Ions in Matter (SRIM) simulation program and considered the cavity pressure during irradiation at target grid. In this investigation, we evaluated the yield of carbon-11 production at different beam currents and the stability of the operation of the KOTRON-13 cyclotron. Results: The production of carbon-11 was enhanced from about 1.700 mCi ($50{\mu}A$) to 2,000 mCi ($60{\mu}A$) on the carbon-11 target which developed by seoul national university bundang hospital (SNUBH) and Samyoung Unitech. Additionally, the cooling condition was showed stable to produce carbon-11 under high beam current. Conclude: The carbon-11 target system of the KOTRON-13 cyclotron was successfully developed and improved carbon-11 production. Consequently, the operation of carbon-11 target system was highly effective and stable compare with other commercial cyclotrons. Our results are believed that this optimal carbon-11 target system will be helpful for the routine carbon-11 production in the KOTRON-13 cyclotron.

• Journal of the Korean Ceramic Society
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• v.38 no.12
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• pp.1155-1161
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• 2001

Yittrium Iron Garnet(YIG) has been used as an important material in the circulator/isolator which is used in RF communication system, mobile phone, adn satellite broadcasting, etc. In this study, we investigated the microstructural and magnetic properties of YIG ferrites with the sintering temperature and additives. We fabricated the YIG ferrites substituted with Ca, In, V by the traditional ceramic sintering method at 1250$\^{C}$, 1275$\^{C}$, 1300$\^{C}$ and 1325$\^{C}$. Powders were granulated by using a spray dryer. Crystallographic and microstructural properties were measured by using XRD and SEM. Magnetic properties were measured by using a VSM for saturation magnetization (4$\pi$M$\_$s/) and FMR (Ferromagnetic Resonance) experiment for ferromagnetic resonance line width (△H). The YIG ferrite, Y$\_$1.6/Ca$\_$1.4/Fe$_4$V$\_$0.7/In$\_$0.3/O$\_$12/, sintered at 1300$\^{C}$, showed higher saturation magnetization and lower ferromagnetic resonance line width than any other sintering temperatures.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.3
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• pp.25-31
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• 2019

This study was conducted to evaluate the penetration performance of the Silane Surface Protection Material (SSPM) penetrating the micro pore of concrete surface. The results was indicated microstructure, porosity and penetration depth of applied SSPM. Silica sand and conventional sand were used as fine aggregate in mortar. And liquid and cream types SSPM were used. The amounts of SPM were applied the 127, 255, 382, 510 g/m2 on the surface of mortar. The penetration depth specimens were made with $100{\times}30mm$ in according with KS F 4930. Penetration depth was evaluated according to KS F 4930, divide specimen and then spraying with water in cross section of specimens, and measure the depth of the non-wetted area. The microstructure result of mortar applied SSPM, it was obtained liquid and cream SSPM in mortar. The porosity results of SSPM application specimens were improved with than that of plain specimens. Test results indicated that the penetration depth of SPM were improved with increasing in amounts of SSPM. As a result of test, application of SSPM to concrete surface, it will improve durability.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.11 no.4
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• pp.113-119
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• 1991

In the present study, a methodology has been established for water budget analysis of a river basin for which monthyl rainfall and evaporation data are the only available hydrologic data. The monthly rainfall data were first converted into monthyl runoff data by an empirical formula from which long-term runoff data were generated by a stochastic generation mothod. Thomas-Fiering model. Based on the generated long-term data low flow frequency analysis was made for each of the oberved and generated data set, the low flow series of each data set being taken as the water supply for budget analysis. The water demands for various water utilization were projected according to the standard method and the net water consumption computed there of. With the runoff series of the driest year of each generated data set as an input water budget computation was made through the composite reservoirs comprised of small reserviors existing in the basin by deficit-supply method. The water deficit computed through the reservior operation study showed that the deficit radically increases as the return period of low flow becomes large. This indicates that the long-term runoff data generated by stochastic model are a necessity for a reliable water shortage forecasting to cope with the long-term water resourse planning of a river basin. F.E.M. program (ADINA) is also presented herein.

• Tunnel and Underground Space
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• v.13 no.1
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• pp.20-32
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• 2003

To understand the behavior of migration of contaminants in a fractured porous medium is a key to assure the overall safety of a potential radwaste repository. The feasible retention mechanism of contaminant transport in a tinctured medium are sorption of contaminants on solid surface and matrix diffusion of contaminants from a fracture into an adjacent porous medium. The acceleration mechanisms are the migration of contaminants in the form of pseudo-colloids and the limit of a volume f3r matrix diffusion. In this paper, the effects of these two acceleration mechanisms are studied mathematically, then semi-analytically computed by the application of the Talbot theorem and verified. Results indicate that the acceleration processes cannot be neglected in the modeling of contaminant transport in a fractured porous medium.

• International Journal of Control, Automation, and Systems
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• v.3 no.spc2
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• pp.315-321
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• 2005

Interactions among multiple control functions of a UPFC installed in a power system have been observed in power system simulation and been reported in authors' previous publications [1,2]. This paper presents new analytical results about these observed interactions and concludes that they are due to the control conflict between the series and shunt part of the UPFC, which are connected through the internal common capacitor inside the UPFC. Investigation in the paper reveals, for the first time as far as the authors are aware of, that the linkage pattern of UPFC series and shunt part decides whether the control functions implemented by the UPFC series and shunt part conflict each other or not. This linkage pattern of UPFC series and shunt part can be described by the flow of active power through the UPFC at steady-state operation of the power system. Hence in order to predict the possible interactions among multiple control functions of the UPFC, an interaction indicator is proposed in the paper which is the direction and amount of active power flow through the internal link of the UPFC series and shunt part at steady-state operation of the power system. This proposed interaction indicator can be calculated from power system load flow solution without having to run simulation of the power system with UPFC controllers installed. By using the indicator, the interactions among multiple control functions of the UPFC caused by badly set controller's parameters are excluded. Therefore the indicator only identifies the possible existence of inherent control conflict of the UPFC.

• Journal of the Society of Naval Architects of Korea
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• v.39 no.2
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• pp.34-44
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• 2002

Approximately 70 percent of shop's hull plate consists of three-dimensional curved shell. Concerning with the research on the automation of plate forming many studies have been carried out for the last decade. The purpose of this study is to develop the simulator of heating on the basis of the reasonable mechanical model representing a heating phenomenon. The beating experiment has been carried out with varying parameters influencing on the results of heating information at the kinematics analysis, simulatorestimate the shape of deformed plate that process along the processing information. When we get the initial shape and the object shape, we calculate the processing information first, using kinematics analysis. In a simulator we estimate deformed shape from the processing information. After this we compare deformed shape and object shape. If the error of deformed shape and object shape is in the proper limits, that information is determined the final processing information. Else we repeat the process changing variable.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.9 no.1
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• pp.73-80
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• 2015

In this paper, we propose the robotic arm control method based on upper extremity electromyogram for lower upper extremity amputation patient. The muscle activity of the forearm flexor, forearm extensor and biceps was analyzed to utilize distribution of muscle activity to a specific position in order to the control input. This control input is converted into a control command for controlling the robotic arm through the algorithm. For the experiment and verify the proposed method, 5DoF robotic arm control system was constructed with 1 channel EMG Module and PC applications through the interworking with each module to perform a three-channel EMG analysis. For accuracy and performance evaluation of control, Experiments were performed with robotic arms moving objects. As a result of experiments which after training for 10 hours by middle 20's man, Validity of the proposed method was evaluated based an average accuracy of 92.5%.