• Journal of Life Science
• /
• v.30 no.5
• /
• pp.476-482
• /
• 2020

In rice agriculture, Eleocharis kuroguwai Ohwi (olbanggae) is a target for herbicidal intervention as a problem weed although it has also long been used clinically as a traditional medicine for jaundice, fever, and blood flow. E. kuroguwai has been evaluated in many clinical trials, but its molecular biological advantages are still unknown. Here, we investigate the anti-inflammatory effects of E. kuroguwai 80% ethanol extracts by screening NO production in LPS-induced macrophage activation. To find the most effective fractions, we partitioned five sub-fractions using HP20 column chromatography, namely 20%, 40%, 60%, 80%, and 100%. Of these, the 60% and 80% sub-fractions were found to significantly inhibit NO production; there were no toxicological effects at any concentration. In addition, the 80% sub-fraction inhibited significantly the iNOS and the mRNA of the pro-inflammatory mediators IL-6, TNF-α, and IL-1β by inhibiting the phosphorylation of JNK and ERK pathways associated with MAPKs signaling. Our results suggest that the 80% E. kuroguwai sub-fraction has the most significant anti-inflammatory effects of inhibiting iNOS and pro-inflammatory mediators and suppressing the phosphorylation of JNK and ERK. Therefore, the 80% sub-fraction of E. kuroguwai extract may be a therapeutic candidate for inflammatory diseases associated with the overexpression of MAPKs.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 1994.04a
• /
• pp.94-99
• /
• 1994

최근 인구의 과밀화와 이에 따른 지가의 상승 등으로 대표적인 주거용 빌딩인 아파트의 고층화가 급속하게 진행되고 있고 아파트에 설치되는 엘리베이터도 점차 대형화, 고속화 되고 있다. 실례로 15층 아파트의 경우 11인승, 60m/min의 엘리베이터가 일반적으로 사용되는 반면, 20층 아파트의 경우 17인승, 90m/min이 주로 사용된다. 이와 같이 엘리베이터의 용량과 운행 속도가 증가함에 따라 필연적으로 소음 및 진동 문제가 발생하게 된다. 특히 아파트의 경우 침실, 공부방 등 고도의 정숙을 요하는 생활 공간이 많고, 내부 공간의 활용도를 높이기 위하여 이들 방들이 엘리베이터 기계실 또는 운행 통로와 직접 접하여 있는 경우도 있어 이 경우 소음, 진동 문제는 아주 심각한 문제로 대두된다. 본 연구소가 측정한 방에 의하면 S신도시 L아파트의 경우 아파트 최상층 방에서 실내 소음도가 46dB(A), 벽의 진동가속도가 3.4mm/s$^{2}$(RMS)으로 나타났다. 진동의 경우 생활에 직접적인 악영향을 미칠 수준은 아니지만 소음의 경우 ASHRAE 권장 주택소음 기준치가 35dB(A) 이하임ㅇㄹ 감안하면 주거에 곤란한 수준이다. 수년전, 고층 아파트가 보급될 초기에는 아파트에 엘리베이터가 설치되어있다는 그 자체만으로 충분한 장점이 되어 다소음 소음, 진동문제는 큰 불만거리가 되지 않았지만 엘리베이터가 보편화된 지금에는 엘리베이터의 편리성만으로는 점점더 크게 요구되는 정숙성이 보상되지 않는다. 따라서 전반적인 아파트의 소음, 진동 문제에 큰 비중을 차지하는 엘리베이터에 의한 소음, 진동에 관하여 체계적인 연구가 필요하다. 이에 본고에서는 엘리베이터에 의한 아파트의 소음 및 진동에 관하여 그 현황, 원인 그리고 대책에 관한여 논하고자 한다.감 방법을 연구하였고, T.Sakai는 5자유도 모델을 이용하여 엔진 공회전시 발생하는 치타음에 대해 이론과 실험을 통해 해석하고, 엔진 회전수 변동, 클러치 특성, 변속기의 드래그(drag) 토크의 영향과 치타음 저감을 위한 개선된 클러치 특성을 제시하였다. 이 외에도 Thomas C.T.와 E.P.Petkus는 특정 차량에 대한 동력전달계의 비틀림 진동 현상에 대해 연구하였다. 이러한 연구들로 볼 때, 자동차 동력전달계에서 발생하는 진동은 이론과 실험을 통해 그 해석이 가능하며 설계에 매우 유용하게 이용되고 있음을 알 수 있다. 따라서, 본 연구는 4 실린더 4 싸이클 1.5 L 엔진을 장착한 경승용차의 실차 주행실험을 통해 가속 페달의 급조작에 따른 차체의 종진동 현상을 측정하고, 엔진-변속기-타이어-차체의 반환정계 4자유도 진동모델로 시뮬레이션을 수행하여 실차 주행실험의 결과치와 비교, 분석한 후 클러치 비틀림 특성을 비롯한 자동차 동력전달계의 각 설계인자들이 차체의 종진동에 어떠한 영향을 미치는가를 해석하고자 한다.be presented.LIFO, 우선 순위 방식등을 선택할 수 있도록 확장하였다. SIMPLE는 자료구조 및 프로그램이 공개되어 있으므로 프로그래머가 원하는 기능을 쉽게 추가할 수 있는 장점도 있다. 아울러 SMPLE에서 새로이 추가된 자료구조와 함수 및 설비제어 방식등을 활용하여 실제 중형급 시스템에 대한 시뮬레이션 구현과 시스템 분석의 예를 보인다._3$", chain segment, with the activation energy of carriers from the shallow trap with 0.4[eV], in he amorphous regions.의 증발산율은 우기의 기상자료를 이용하여 구한 결과 0.05 - 0.1

• The Journal of the Korea Contents Association
• /
• v.13 no.7
• /
• pp.51-61
• /
• 2013

This Paper aims to explore the key factors that drive box-office success in Korean, Chinese and Japanese film market regarding to the storytelling of the movies. At first, I researched the top 20 movies at the box office of Korean, Chinese and Japanese film market from 2007 to 2011.And then I tried to figure out the key factors for the success and the differences among those countries. Usually the purpose of the movie planning in Korea is for the domestic market. In the profit structure of Korean film industry, it is really hard to focus on the overseas film market. In Chinese film market, recently it has been changed a lot especially film genre. The movie liked to watch is melodrama, romantic comedy movie It is being changed to the comedy genre from the war and martial arts movie. And it is emphasized the importance of the scenario in the film production. They want to watch their lives like a real and dreams at the movie and the movie tries to show this trend. In Japanese film market, they made movies in which TV drama, animation and cartoon according to the O.S.M.U. strategy. The movies like to watch are the blockbuster movies, horror movies, thriller movies and melodrama. Comparing with Korea and China, they like movies which show more fantastic and fairy tale imagination.

• Journal of Digital Convergence
• /
• v.12 no.5
• /
• pp.139-148
• /
• 2014

In recent years, computational models using parametric estimation method have been developed and used widely for efficient cost analysis. In this research, by applying experienced data from Guidance and Control Systems in Missile System field, the cost analysis for engineering model and commercial computational model(Price H, HL, M, S) are conducted and its result is analysed, so that the difference between two models and its grounds are apprehended. Comparing the calibrated value of computational model based on the data base of similar equipment and the cost from the engineering estimation, the two results are very close. It means that the credibility of data is enhanced through calibration. Also, for cost analysis of similar components in the future, the method for calibration of the computational models is also examined. When estimating development cost in this research, although many parts have been estimated through uncertain elements, the reliability could have been enhanced by applying computational model which secures objectivity. It is a very reasonable estimation method by utilizing calibration of the computational models based on existing accumulated development data.

• Korean Journal of Construction Engineering and Management
• /
• v.18 no.1
• /
• pp.74-82
• /
• 2017

It is known that energy usage from Korean Universities was growing rapidly in the early 2000s. But since 2011, the change was caused by GHG emissions regulation enforced by the government. The purpose of this research was to find the characteristics and trends of greenhouse gas emissions from major universities in Korea according to the each university's data and information. The result shows that GHG emissions from University have increased steadily prior to enforcement by 4-5% annually, but the rate of increase marked 0.5~1% in 2011~2013 is the season of emission regulation and the total amount of emissions decreased 3%~5% in 2014~2015 while preparing an emissions trading scheme. Therefore we can say that the enforcement of GHG reduction such as energy target management system makes a visible effect at least in the University sector that level of GHG emissions is from $75kg/m^2$ to $58Kg/m^2$ for seven years. Another result says that the size of research fund is the main factor that affects the amount of GHG emissions before 2011, but the size of building area has been a new factor influencing the GHG emission since 2013. Thus we suggest that the criteria for evaluating the level of GHG emission from University is suitable if it is based on the building area intensity.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.23 no.4
• /
• pp.283-288
• /
• 2003

This study was carried out to a comparison of nutrient value and total digestible nutrient yield f3r select the promising barley cultivar for whole crop silage in paddy field of Suwon from 1998 to 2001. In milk stage, acid deferent fiber(ADF) content of barley were 27.3 ∼ 29.1, 27.4 ∼ 30.4 at yellow ripe stage. Neutral deferent fiber(NDF) content of milk and yellow ripe stage were 50.6 ∼ 55.9 and 53.1 ∼ 00.0. Also, total digestible nutrient(TDN) content of milk and yellow ripe stage we.e 65.4 ∼ 67.4 and 64.3 ∼ 67.7. And TDN yield at milk and yellow ripe stage were 4,120 ∼ 5,528 and 5,674 ∼ 6,569 MT per ha and in vitro dry matter digestibility(IVDMD) at milk and yellow ripe stage were 65.8 ∼ 74.6 and 64.6 ∼ 73.9. The for promising barley cultivars for whole crop silage in paddy field were Albori at Suwon. it was best before yellow ripe stage for harvest in cropping system.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.10
• /
• pp.182-188
• /
• 2016

A decoy is a weapon system that can protect vessels from an enemy's torpedo. Thus, the decoy should be able to operate in the field without any failure. Because the decoy can be inoperable once its sealing is broken and water permeates inside the system, the hermetic sealing capability considering the operational environment is mandatory. To be hermetically sealed, a rubber-type O-ring is generally used in a decoy system. The sealed performance of rubber-type products, however, tends to age and deteriorate with time. Therefore, the O-ring needs to be maintained or changed periodically. This paper proposes a method to estimate the proper maintenance period using the hardness and elongation percentage, which represents the performance of the O-ring product and test data from Accelerated Life Test (ALT) of the product. The O-ring used in this paper is a NBR type, and the temperature was chosen to be the main accelerating factor as referenced in many studies. The criteria for the failure of the O-ring was set for the product to be 50% degraded compared to the initial performance. In addition, the Korean standard KS M 6518 was adopted and referenced for the preparation of test samples and the calculation of estimates. The O-ring's predicted life was simulated by analyzing the test results from a computer program, and the optimized maintenance period for the product was determined.

• Journal of Korean Philosophical Society
• /
• v.130
• /
• pp.23-45
• /
• 2014

It can be said that Scheler's theory of perception is the theory of drive-conditioned perception, in more detail the theory of drive-motoric conditions of perception. Scheler tells us that Immanuel Kant and Ernst Mach were mistaken in their assumption that sensations are purely receptive and primary in all experience. He claims that sensations are not primary but subsequent to a subliminal attention of vital drives(called 'Vor-Liebe und Vor-Interesse' by him). And because sense perception cannot take place without a vital energy of drives that account for the ongoing activity of perception, no object can be perceived unless it stimulates movement in an organism which exercises a count-movement against objects and thereby resisting objects. According to Scheler, an order of foundation such as the preexistence of images prior to perception; the priority of perception with regard to functions of senses; the priority of sense functions with regard to sensations has to be kept in mind. And it has to be kept in mind that the essence of life is pre-empirical, is pure becoming(Werden) and unbecoming(Entwerden), a process in which its two empirical sides are not yet separated. Then it is easy to see that perception is conditioned by vital drives. The drive-conditioned theory of perception is also supported by the fact that the motility of an organism determines its sensory apparatus, an organism has an alphabet of senses that can serve as signs of luring and noticing objects that are meaningful for its drive-motoric behavior. For example a lizard remains undisturbed by a gun shot but runs away from the slightest noise in the grass.

• Industry Promotion Research
• /
• v.4 no.2
• /
• pp.9-18
• /
• 2019

This study investigated the relationship between ICT environment and business performance. In the case of Korea's major industries, large corporations have already established and operate a considerable level of smart factories, leading the global market. However, SMEs, which account for 95% of the total companies, are not able to build smart factories themselves. Smart factory construction The total number of government-supported enterprises is 4.891 companies (3,984 companies, 907 companies in construction) 2.9% of factories and 97.1% (166,344 companies) There is a big problem to be improved. The result of this study is that the first research objective of this study, which suggests the theoretical system that the will of the manager is most important for the successful establishment of the smart factory, which is part of the corporate innovation to meet the rapidly changing environment. Second, it can be seen that financing for building a smart factory is a key factor in building a smart factory, as well as funding itself. Third, it was found that besides its own technology, technology support for government and external technology consulting support are very important for smart construction. Fourth, organizational participation of internal organizers showed that cooperative and positive positive participation is also a factor of success. As a follow-up study, we analyzed the cause of the company's operation, analyzed the cause of the problem with the 4M1E technique, developed the countermeasures, and compared it before and after the improvement, standardized the improvement and needed further study. It is meaningful that the study provided basic data for building a smart factory through the analysis of the relationship between the ICT environment and business performance of the company.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.4
• /
• pp.479-488
• /
• 2019

The flight test operational procedure artifact includes mission planning, execution methods, and safety measures for each step of test progress. As the development of guided missiles has become more advanced and strategic, flight test has become increasingly complex and broadened. Therefore, increased reliability of the flight test operation procedures was required to ensure test safety. Particularly, the design of the flight test operational procedures required verification through M&S to predict and prepare for the uncertainty in a new test. The relevant studies have published the optimal framework development for flight tests and the model-based improvements of flight test processes, but they lacked the specificity to be applied directly to the flight test operational procedures. In addition, the flight test operational procedures, which consist of document bases, have caused problems such as limitations of analysis capabilities, insensitive expressions, and lack of scalability for the behavior and performance analysis of test resources. To improve these problems, this paper proposes how to design operational procedure of guided missile flight test system by applying MBSE(Model-based Systems Engineering). This research has improved reliability by increasing the ability to analyze the behavior and performance of test resources, and increased efficiency with the scalability applicable to multiple flight tests. That can be also used continuously for the guided missile flight tests that will be developed in the future.