• 한국산학기술학회논문지
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• 제18권7호
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• pp.375-381
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• 2017

성토지지말뚝의 아칭효과를 실험적으로 살펴보고자 현장시험을 수행하였으며 계측결과로부터 구한 아칭효율을 이론식에 의한 값과 비교해 보았다. 성토지지말뚝의 아칭효과를 살펴보기 위해 측정한 하중계 및 토압계에 의한 계측값들은 대체적으로 성토지지말뚝의 아칭효과를 반영하였다. 하중계 측정값을 통해 볼 때 아칭효율은 성토고 3m 까지는 평면변형률 조건을 가정한 이론식에 의한 값보다 작았으나 4m 이상에서는 이론식에 의한 값보다 큰 값을 보였으며 이론식에 의할 경우, 아칭효율은 성토고에 따라 감소하는 경향을 보였으나 측정결과는 성토고에 따라 아칭효율도 증가하는 경향을 나타내었다. 현장 시험에서 계획했던 최종 성토고까지 비교적 원활하게 작동하였던 토압계에 의한 계측결과에 따르면, 성토고에 따라 평면변형률 조건을 가정한 이론식에 의한 값보다 큰 아칭효율을 나타내었으며 4m 이상의 성토고에 대해서는 아칭효율의 변화양상 또한 이론식과 유사한 경향을 보였다. 토압계 측정결과에 따르면 성토고 2m, 3m, 4m, 5m 그리고 6m일 때의 아칭효율은 평면변형률조건을 가정한 이론식에 의한 아칭효율에 비해 각각 1.05배, 1.23배, 1,29배, 1.28배 그리고 1.29배 큰 값들을 보여 우수한 아칭효과를 보임을 알 수 있었다. 현장시험을 통해 얻은 하중계 및 토압계 측정값들로부터 계산된 아칭효율은 말뚝을 격자배치한 경우에 대한 이론식에 의한 그것보다 상당히 컸다.

• 대한의생명과학회지
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• 제23권3호
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• pp.230-237
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• 2017

Changes in the activity of alkaline phosphatase (ALP) isoenzymes and isoforms in human serum have a major diagnostic value, therefore the regulation of ALP activities is a valuable target for therapeutic interventions. To assess the pharmacological activity of retinoids, i.e., all-trans retinoic acid and 13-cis retinoic acid, their tissue-specific inhibitory effect on human serum ALP activity was elucidated by chemical inhibition methods, heat-sensitive inactivation, and wheat-germ lectin precipitation test. Retinoids showed significant inhibition of the total ALP activity in human serum at a concentration of 5 mM. All-trans retinoic acid (5 mM) and 13-cis retinoic acid (5 mM) inhibited ALP activities by up to 12% and 15%, respectively, compared to that by guanidine hydrochloride (200 mM). L-phenylalanine (100 mM) and urea (30 mM) had no further inhibitory effect on ALP activities in human serum pretreated with retinoids (5 mM). Retinoids significantly inhibited ALP activities by up to 20% compared with that of tetramisole (30 mM). The ALP activities in retinoid-pretreated serum remained unchanged after the heat inactivation process. These results suggest that retinoids are inhibitors of the intestinal ALP isoenzyme. Remarkably, retinoids revealed potent inhibitory activities against ALP in wheat-germ lectin precipitant serum, indicating that they also function as inhibitors of the bone ALP isoform. The results show that retinoids inhibit the specific tissue-derived human serum ALP activities, moreover, the inhibitory effect of retinoids against bone ALP activity suggests their clinical utility as monitoring and prevention of metastasis of bone cancer.

• KSBB Journal
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• 제15권6호
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• pp.621-629
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• 2000

전남의 여수지역의 해양에서 carotenoid를 생산하는 세균을 분리하여 상용하였으며, 이 세균은 Curtobacterium sp.으로 동정되었다. 해양세균 Curtobacterium sp.의 carotenoid 생산 최적조건은 pH 7.0, 최적온도 $25^{\circ}C$, 탄소원으로서는 4 mM의 fructose, 질소원으로서는 0.07%의 tryptone, 미량원소 및 growth로서는 각각 0.5 mM의 $Mg^{+2}$ 이온, $1{\;}\mu\textrm{m}$의 cytocobalamine이었으며, 이 최적조건에서의 carotenoid의 생산량은 $13.0{\;}mg/\ell$ 였다. 해양세균 Curtobacterium sp.로 부터 생산된 carotenoid는 tunaxanthi (86.6%), diatoxanthin (7.1%), ${\beta}-carotene$ (2.1%), canthaxanthin (19.1%), cynthiaxanthin (1.9%) 5가지의 다른 성분으로 구성되어 있었으며, 주로 tunaxanthin을 생산하는균주로 사료된다. 그리고 분리 정제하지 않은 crude corotenoid을 이용한 생리활성 시험에서 E. coli 및 L. bulgaricus 등에 대해서는 항균활성은 나타내지 않았으나, HepG2 (hepatocellular carcinoma, human, ATCC HB-8065) 및 HeLa (cervical carcinoma, human, ATCC CCL-2) 등의 암세포에 대하여 각각 86.4% 및 39.2%의 강한 저해 활성을 나타내었다. CCL-13 (diploid, monotypic hepatocyte, huma, ATCC CCL-13) 세포를 사용한 항산화 활성은 $50{\;}\mu\textrm{g}/m{\ell}$의 carotenoid의 농도에서 83%의 강한 항산화 활성을 보였고, DPPH법에 의한 Free radical의 소거 기능도 43.4%의 높은 활성을 나타내었다. 따라서 해양세균 Curtobacterium sp.로부터 생산된 이 carotenoid는 정제하지 않은 상태로도 어류 및 축산사료, 첨가물, 항산화제, 의약품 등의 다양한 분야에 사용이 가능할 것으로 판단된다.

• 한국생활과학회지
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• 제15권5호
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• pp.811-821
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• 2006

The purpose of this report was to study visual effect and functional effect of waist line location of slacks for females in 20'. 1. Differences of visual effect of slacks waist line change to be expressed that mature, sexual and casual slacks waist line were W4 or W5, looks like long leg and mature and formal slacks waist line was W1, slim lower part of the body and flat slacks waist line was W4. 2. Analysis result of functional effect difference with the location variation of slacks waist line were as follows. In all motions(M1, M2, M3, M4) W2 that downed 7cm-6cm-6cm from natural waist line was valued as the most comfortable, W1 and W5 were valued as discomfortable, where waist line was too high or too low.

• Journal of Nutrition and Health
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• 제29권8호
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• pp.881-888
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• 1996

The purpose of this study was to determine whether vitamin B6(B6) deficiency affects fuel utilization and blood cholesterol profile with exercise-training. Twenty-four rats were fed a B6 deficient(-B6) diet or a control (+B6) diet for 5 weeks and either exercised(EX) or nonexercised (NE). EX rats were exercised on treadmill(10$^{\circ}$, 0.5-0.8km/h) for 20 minutes everyday. Glucose(GLU), glycogen (GLY), protein(PRO), trglyceride(TG), free fatty acid(FFA), total cholesterl(TC), HDL-cholesterol(HDL-C) and LDL-choleterol(LDL-C) were compared in plasma(P), liver(L) and skeletal muscle(M) of rats. There was a vitamin effect on the level of P-GLU, P-TG, M-TG, L-GLY, L-PRO and an exercise effect on the level of P-PRO, P-FFA, M-PRO, L-GLY, L-TG, P-TC, P-HDL-C, P-LDL-C. Compared to +B6 rats were lower and there were no differences in P-GLU, P-FFA, P-TG. M-GLY, L-TG, P-TC and P-HDL-C. In EX group, the level of P-TG was higher and M-PRO was lower in -B6 rats. There were no differences in M-GLY, L-TG, P-TC and P-HDL-C. These results suggest that a lowered intake of vitamin B6 may impair the adaptation of animals to fuel metabolism related to a decrease of fatty acid oxidation and attenuates the exercise-traning effect on blood lipid profile.

• 한국환경과학회지
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• 제11권6호
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• pp.561-567
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• 2002

This study was investigated to evaluate the effect of the sodium ion and pH on toxicity of dinitrophenol at high concentrations (0.41 to 0.54 mM), over a sodium concentration range of 0.1 mM to 107 mM and over a pH range of 5 to 9. The concentration of sodium ions in the activated sludge mixed liquor seemed to have very little effect on dinitrophenol toxicity. However, lack of sodium in the growth media resulted in a reduction of the dinitrophenol degradation rate by bacterial isolate from the activated sludge culture, which has been identified as Nocardia asteroides. Dinitrophenol inhibition was found to be strongly dependent on mixed liquor pH. The dinitrophenol degradation rate was highest in the pH range of 6.95 to 7.84; at pH 5.94 degradation of 75 mg/L dinitrophenol was significantly inhibited; at pH < 5.77, dinitrophenol degradation was completely inhibited after approximately 30% of the dinitrophenol was degraded.

• Asian-Australasian Journal of Animal Sciences
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• 제12권2호
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• pp.161-164
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• 1999

Dairy performances of Pabna cows and its crossbreds with Sahiwal (SL) and Friesian (F) in the Baghabarighat dairying area of Bangladesh were evaluated. Four SL and three F sires were used for the crossbreeding. The exotic sire effect of individuals on their daughters were also evaluated in this study. It showed that the genetic group had a significant (p<0.05) effect on birth weight, age at first heat, calving interval, lactation length and lactation yield. The lowest birth weight (17.9 kg), longest age at first heat (39.2 m) and calving interval (16.3 m) shortest lactation length (199 d) and lowest lactation yield (728 L) were found in Pabna cows. The highest birth weight (22.5 kg). shortest age at first heat (25.5 m) and calving interval (13.7 m), longest lactation length (253 d) and highest lactation yield (1936 L) were found in the F crossbreds. Within the same breed, the effect of individual sire was significant (p<0.05) on age at first heat, lactation length and lactation yield. Individual sire effects of SL bulls differed significantly (p<0.05) but F sires had a non-significant (p>0.05) effect on calving interval in their progeny. The fat % and SNF % in milk and number of services required for conception did not differ (p>0.05) among inter-and intra- breed sire groups.

• 경영과정보연구
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• 제4권
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• pp.327-348
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• 2000

There are three major motives for M&A, financial synergy effect, operating & managerial synergy effect, and tax effect. The purpose of this study is to prove the operating & managerial synergy effect of M&A. To do this, we analyze the market-ripple effect of M&A, focusing on the increase in market power. Specifically we use cross-sectional data from 1985 to 1998 to show whether a market power of mergers is higher than that of a matched non-merging control group. we use time series data to show whether a market power of merger is higher than that of pre-merger. Also we use the event study using market model to show the stock price movement after mergers. The result is that although revenue increase after mergers, profit of the firms does not improve after mergers. Also there is sufficient evidence to say that there is a cumulative abnormal return for the firms after mergers.

• 한국안전학회지
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• 제12권2호
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• pp.17-21
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• 1997

The fatigue crack propagation rate has so far been measured by the effective stress intensity factor range Δ K/sub eff/. But no research has been done to study how much the crack opening ratio influences the expectation of the fatigue crack propagation. Therefore, this paper evaluates of the crack opening ratio on the fatigue crack propagation life by using the method of parameter sensitivity study. Summarizing the result ; ( 1 ) When the crack opening ratio U' is high, the effect of U' gets larger than any other except for the material factor m. But when U' is low, the effect is also diminished. Therefore, the selection of the lowest value possible is desirable in the evaluation of life. (2) When the value of the material factor m is high, the effect of crack opening ratio U' is increased, at the same time the effect of the other parameters also increased wholly. The effect of material factor m itself on life is high, but in case the material factor m is high, that the effect of each parameter on life get higher is unique. In designing, better attention to the material selection should be drawn. (3) In case the stress ratio R gets smaller, the effect of crack opening ratio U' is unchangeable. But the effect of R itself remarkably decreases, and the effect of material factor m somewhat decreases.

• 한국운동역학회지
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• 제29권4호
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• pp.205-211
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• 2019

Objective: The purpose of this study was to analyze the effects of skill and distance factors on CoP (Center of pressure) and CoM (Center of mass) during golf putting. Method: 38 golfers were participated in this study. 8 motion capture cameras (250 Hz) and 2 force plates (1,000 Hz) were used to collect CoP and CoM during 2 m and 3 m of distance golf putting. To identify main effect and interaction effect, it was performed Two-Way ANOVA at a significant level of a .05. Results: In the novice group, CoP distance was significantly difference in the A/P direction and main effect between skill level and distance. Both groups indicated that CoP distance was significantly different and main effect between skill level and distance in the M/L direction. Finally, both groups showed that CoM was significantly different and main effect between skill level and distance in the M/L direction. Conclusion: Therefore, novice golfers are expected to be able to perform more accurate and proper putting exercise through the practice of minimizing the center of mass(CoM) and center of pressure (CoP) in the M/L direction, which is the pendulum movement of the putter head.