• Journal of the East Asian Society of Dietary Life
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• v.14 no.1
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• pp.64-69
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• 2004

The deficiency of the neurotransmitter acetylcholine(ACh) is responsible for the initiation of Alzheimer's disease. In addition, there is a simple evidence that oxidative stress significantly increases in persons with Parkinson's disease compared to age-matched healthy persons. Therefore, the objective of the study was to investigate the neurodegeneration inhibitory effect of soybean(Glycine Max) and Yak-Kong(Rhynchosia Nolubilis) by measuring the degree of inhibiting Acetylcholinesterase (AChE) catabolizing the ACh and the free radical scavenger effect in vitro. AChE was measured by the minor modified Ellman assay. Free radical scavenging activity was measured using l-diphenyl-2-picrylhydrazyl (DPPH). First, the MeOH extracts of Soybean and Yak-Kong showed the AChE inhibiting activity of 62.0$\pm$2.43％ and 65.0$\pm$3.29％ at the 5 mg/$m\ell$ concentration. The 50％ inhibitory concentration ($IC_{50}$/) of AChE was 1.96 and 1.31 mg/$m\ell$ in the MeOH extracts of soybean and Yak-Kong. Second, the MeOH extracts of soybean and Yak-Kong showed the free radical scavenger activity of 23.1$\pm$4.26％ and 80.7$\pm$4.61％ at the 5 mg/$m\ell$. IC50 of free radical scavenger activity in Soybean and Yak-Kong was 13.00 and 1.41 mg/$m\ell$ in MeOH extracts and was 5.95 and 2.74 mg/$m\ell$ in hot-water extracts, respectively. In this study, the extracts of Soybean and Yak-Kong showed powerful effects in the AChE inhibition and free radical scavenging. The extracts of Soybean and Yak-Kong were expected to prevent the many neurodegenerative diseases.

• Korean Journal of Soil Science and Fertilizer
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• v.42 no.4
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• pp.231-238
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• 2009

This study was carried out to investigate the effect of vegetative buffer to reduce runoff and soil and nutrient loss at highland agricultural area. The soil of experimental field was classified as Ungyo series (Fine, Humic Hapludults). An area of each field with lysimeter was $50m^2(width\;2.5m{\times}length\;20m)$ and was a gradient of 17%. Chinese cabbage (Brassica campestris L.) was cultivated by general management in each field. For establishing vegetative buffer, rye (Secalecereale L.), tall fescue (Festucaarundinacea Schreb) and orchard grass (Dactylis glomerata L.) were planted at the edge of field. Rye buffers were 1m, 2m and 4m wide. Both orchard grass and tall fescue buffers were 2m wide. Vegetative buffers were set up in September 2005 and chinese cabbage was planted in June 2006. Soil loss, runoff and nutrient loss were measured from June to August in 2006. Since the precipitation amount was heavy in July, amounts of runoff, soil erosion and nutrient loss were the highest in July during this study period. In comparison with control, vegetative buffers of rye 2m, orchard grass 2m and tall fescue 2m reduced runoff by 3%, 1% and 2%, respectively. In comparison among width of rye buffer, rye 1m, rye 2m, and rye 4m reduced by 1%, 4% and 13%, respectively. Vegetative buffers of rye 2m, orchard grass 2m and tall fescue 2m showed the reducing of soil loss by 59%, 46% and 28%, respectively. In comparison among width of rye buffer, the highest reducing effect of 88% was observed in 4m treatment. Additionally, vegetative buffer reduced N, P and K losses in runoff and eroded soil which were 10 to 54%, 7 to 24% and 11 to 21%, respectively. In different widths, wider vegetative buffer showed lower loss of N, P and K in runoff and eroded soil. As a result of this study, the vegetative buffer of rye was most effective for reducing runoff and soil loss in comparisons with other plants. In addition, wider range of buffers recommended for reducing runoff and soil loss, if possible.

• Journal of the Korean Recycled Construction Resources Institute
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• v.9 no.4
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• pp.478-482
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• 2021

In this paper, methods for manufacturing shielding concrete by recycling steelmaking slag discarded as industrial waste and measuring the shielding effectiveness of the shielding concrete were studied. By comparing the result of shielding effectiveness measurement of this concrete block with shielding effectiveness measurement of the structure constructed with this concrete, the measurement system for measuring shielding effectiveness of the concrete block was verified. The size of the concrete stru ctu re is 2.9 × 2.9 × 3.4m and the concrete block is 0.3 × 0.3 × 0.2m. The frequ ency band u sed for mesu rement is 600MHz - 2GHz, the types of concrete u sed to measu re the shielding effectiveness are general concrete and concrete containing electric arc furnace oxidizing slag. In the case of the concrete structure, reinforcing rebars are installed at intervals of 15cm for stru ctu ral safety, as the frequ ency increase, the electromagnetic wave properties of rebars gradu ally decreased, there was a slight difference in the measurement results. In conclusion, the measurement result of shielding effectiveness of the concrete block is similar to the result of the concrete structure. It is thought that it can be sufficiently utilized for electromagnetic wave engineering design, and the concrete shielding effectiveness measurement system using standard specimens was verified.

• Food Science and Preservation
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• v.25 no.1
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• pp.117-123
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• 2018

This study was designed to determine the biological activities of Chionanthus retusus flower extracts. Water and 90% ethanol extracts of C. retusus flower were prepared. The inhibitory activities of water and ethanol extracts with a phenolic content of $200{\mu}g/mL$ against xanthine oxidase were 25.60% and 15.92%, respectively. Further, the water extract did not show any inhibitory activity against ${\alpha}$-glucosidase whereas the ethanol extract showed 100.00% inhibition of ${\alpha}$-glucosidase. The inhibitory activities of the extracts against tyrosinase were 17.27% (water extract) and 36.13% (ethanol extract), which suggest that the extracts may have a whitening effect. The water extract did not inhibit elastase activity but showed a collagenase-inhibitory activity of 20.21%. On the contrary, the ethanol extract showed 96.26% and 35.93% inhibition of collagenase and elastase, respectively. These findings suggest that the extracts may have an anti-wrinkle effect. Lastly, the extracts showed a hyaluronidase inhibitory activity of 36.96% (water extract) and 88.70% (ethanol extract), suggesting that they may have an anti-inflammatory effect. The results indicate that C. retusus flower extracts containing phenolic compounds can be used as functional resources because they have anti-gout, carbohydrate degradation-inhibitory, whitening, anti-wrinkle, and anti-inflammatory effects.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.5
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• pp.572-580
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• 2017

The contents of phenolic compounds in water and 40% ethanol extracts from Okkwang (Castanea crenata) chestnut bur solid (OCS) were $11.24{\mu}g/50{\mu}g$ solid and $10.28{\mu}g/50{\mu}g$ solid, respectively. The 1,1-diphenyl-2-picrylhydrazyl free radical scavenging and 2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulfonic acid) radical decolorization activities of water and ethanol extracts were 85% and 100% as well as 87% and 86% at a solid content of $50{\mu}g/mL$, respectively. The anti-oxidant protection factors (PFs) of water and ethanol extracts at a solid content of $200{\mu}g/mL$ were 1.22 PF and 1.45 PF, respectively. Thiobarbituric acid reactive substance were 83% in water extract and 73% in ethanol extract at a solid content of $200{\mu}g/mL$. The inhibitory activities against xanthine oxidase in water and ethanol extracts were 54% and 43% at a solid content of $200{\mu}g/mL$, respectively. The inhibitory activities against ${\alpha}$-glucosidase were 95% in water extract and 96% in ethanol extract at a solid content of $50{\mu}g/mL$. Tyrosinase inhibitory activity was 27% in ethanol extract at a solid content of $200{\mu}g/mL$. The collagenase and elastase inhibitory activities as anti-wrinkle effect were 93% and 11% in water extract as well as 94% and 56% in ethanol extract at a solid content of $200{\mu}g/mL$. Hyaluronidase inhibitory activity as anti-inflammatory effect of water and ethanol extracts were 96% and 52% at a solid content of $200{\mu}g/mL$, respectively. The results show that extracts from OCS can be used as a functional resource with antioxidant, anti-gout, carbohydrate degradation inhibitory, whitening, anti-wrinkle, and anti-inflammatory activities.

• Food Science and Preservation
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• v.18 no.1
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• pp.65-71
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• 2011

We explored the effect of extracts of dried Platycodon grandiflorum on production of reactive oxygen species (ROS), glutathione (GSH) and nitric oxide (NO). To determine antioxidant activity in the presence of $H_2O_2$-induced oxidative stress, DCFH-DA (dichlorodihydrofluorescin diacetate) assay was employed. Acetone/methylene chloride (A+M) and methanolic (MeOH) extracts of P. grandiflorum reduced intracellular ROS levels. Of the various tested fractions, n-BuOH fraction showed the highest protective effect in terms of lipid peroxide production. Total GSH levels were measured after treatment of HT1080 cells with the A+M and MeOH extracts, and other solvent fractions, at various concentration. The A+M extacts and 85% (v/v) aqueous MeOH fraction significantly increased GSH levels (p<0.05). When lipopolysaccharide (LPS)-induced NO production was evaluated, all tested crude extracts, and fractions thereof, significantly reduced NO production (p<0.05), and the n-BuOH and 85% (v/v) aqueous MeOH fractions (at 0.05 mg/mL) showed the strongest inhibitory effects. The results showed that the n-BuOH fraction inhibited both cellular oxidation and NO production, and this fraction may thus contain valuable active compounds.

• Journal of Life Science
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• v.18 no.9
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• pp.1271-1277
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• 2008

We investigated to determine the inhibitory effects of solvent extracts from dried onion on growth of cancer cell lines (HT-1080 human fibrosarcoma and HT-29 human colon cancer cells) and $H_{2}O_{2}$-induced oxidative stress. Two different drying methods, low temperature vacuum dryer and freeze dryer, were employed to dry onion. Inhibitory effects of acetone with methylene chloride (A+M) and methanol (MeOH) extracts from onion by two drying methods on the growth of HT-1080 and HT-29 cancer cells increased in a dose dependent manner (p<0.05) and the higher inhibitory effect was shown in onion extracts dried by low temperature vacuum dryer. The treatments of hexane, 85% aq. methanol, butanol and water fractions significantly inhibited the growth of both cancer cells (p<0.05) and onion fractions dried by freeze dryer showed a higher inhibitory effect compared with those dried by low temperature vacuum dryer. In order to determine a protective effect on H2O2-induced oxidative stress, DCHF-DA (dichlorodihydrofluorescin diacetate) assay was conducted. All fractions including crude extracts of dried onion appeared to significantly reduce the levels of intracellular reactive oxygen species (ROS) (p<0.05). Higher antioxidant effect was observed in onions dried by the low temperature vacuum dryer method. These results indicate that the low temperature vacuum dryer is useful to dry and produce onion powder.

• Fire Science and Engineering
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• v.23 no.5
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• pp.143-152
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• 2009

The numerical analyses for each single simplified shaft with three type openings were carried out by using computational fluid dynamics model for the calculation of the pressure difference and the location of the neutral plane and the visualization of stack effect. As the height of shaft heighten, the pressure difference of stack effect is much deviated against the theoretical value. For the Type A models shorter than 30 m height of shaft and the Type B models longer than 30m, the simulation results for the location of the neutral plane are well agreed to the theoretical values with 5% less deviations just after the beginning of simulation (t = 10s). For the Type B models longer than 30m with multiple openings, therefore, it is possible to calculate the location of the neutral plane by using a CFD model. The phenomenon of the air flow of stack effect can be easily understood with the visualization of stack effect.

• Applied Biological Chemistry
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• v.6
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• pp.37-43
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• 1965

8-Hydroxyquinoline, known to have the therapeutic effect to fusarium; and to diminish the amount of evaporation because of reducing the size of the stomata, and a new compound, phenylmercuric 8-oxyquinolinate, were synthesized. The fungicidal effect and diminishing effect of evaporation in phenylmercuric 8-oxyquinolinate were studied and the results are as follows. 1) 8-Hydroxyquinoline(m.p. $74{\sim}75^{\circ}C$, white needle crystalline) was synthesized by Skraup's method, 2) Phenylmercuric 8-oxyquinolinate(m.p. $159{\sim}160^{\circ}C$, yellowish brown needle crystalline) was synthesized by reacting phenylmercuricacetate to 8-hydroxyquinoline. 3) The orders of the fungicidal effects are; a) To Cochliobolus miyabeanus P.M.A.

• Journal of Applied Biological Chemistry
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• v.64 no.2
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• pp.133-140
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• 2021

In this study, we investigated the antibacterial, antioxidant, and whitening effects of Prunus persica Batsch var. davidiana Max. (Feral Peach) and Prunus mume (white and pink) flowers. The extracts of the three kinds of flowers showed antibacterial activity against Staphylococcus. aureus. The chloroform fractions of the white Prunus mume, Feral Peach, and pink Prunus mume flowers exhibited antibacterial activities of 84, 49, and 30%, respectively, against Staphylococcus. aureus at a concentration of 0.5 mg/mL. The flower extracts of the three species also exhibited antibacterial effects against Pseudomonas. aeruginosa. The chloroform fractions of the Feral Peach and pink Prunus meme flowers exhibited antibacterial activities of 36 and 30%, respectively, at a concentration of 0.5 mg/mL. These extracts did not exhibit any significant antibacterial activity against Staphylococcus. epidermidis and Escherichia. coli. The extracts of the three kinds of flowers did not significantly affect the survival of HaCaT cells. The distilled water fraction of the pink Prunus mume flower extract exhibited antioxidant effects at concentrations of both 20 and 40 ㎍/mL. The ethyl acetate fraction of the pink Prunus mume flower extract exhibited an antioxidant activity superior to glutathione at a concentration of 40 ㎍/mL. The flower extracts did not significantly affect the survival rate of B16F10 cells. The chloroform fraction of the Feral Peach flower exhibited a whitening effect of 18% at a concentration of 40 ㎍/mL. Based on these results, we conclude that the three kinds of flower extracts are raw materials exhibiting antibacterial, antioxidant, and whitening effects.