• Journal of Acupuncture Research
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• 제30권5호
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• pp.219-226
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• 2013

Objectives : The purpose of this study is to report the effect of Korean medicine treatment on a patient with brachial plexus injury. Methods : The patient with symptoms of pain and dysesthesia on right forearm and hand was treated with acupuncture treatment, herbal medicine, moxibustion and physical treatment. Improvement of the patient's symptoms was evaluated by Hepatic dullness sound, NRS, VAS, SF-36 bodily pain, grip strength. Results : After 42 days of treatment, NRS score significantly decreased. VAS score, SF-36 bodily pain and grip strength showed moderate improvement. Conclusions : This results suggest that Korean medicine treatment may be effective in reducing the symptoms of brachial plexus injury.

• 대한상부위장관⦁헬리코박터학회지
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• 제18권3호
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• pp.209-212
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• 2018

We report a rare case of systemic amyloidosis with gastrointestinal and lymph node involvement. A 64-year-old woman was admitted to our hospital with dyspepsia and weight loss. Initial esophagogastroduodenoscopy (EGD) revealed nonspecific findings, and abdominal computed tomography showed necrotizing lymphadenopathy at the porta hepatis. Laparoscopic lymph node biopsy was performed under suspicion of tuberculous lymphadenopathy, but a definite diagnosis was not established. Follow-up EGD performed 6 months later revealed multiple telangiectasia-like lesions at the gastric body, and endoscopic biopsy revealed amyloid deposition. Through additional blood and urine protein electrophoresis, the patient was finally diagnosed with systemic amyloidosis associated with multiple myeloma. She was treated with dexamethasone, thalidomide, and bortezomib; however, she died 3 months after diagnosis because of pneumonia and multiple organ failure.

• 대한세포병리학회지
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• 제3권2호
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• pp.60-66
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• 1992

Islet cell neoplasms (ICNs) of pancreas are uncommon, and the cytologic features of ICN are not well delineated. We report a case of islet cell tumor with lymph node metastasis, describing the cytologic, histologic, and immunohistochemical findings. A 40-year-old woman was admitted due to upper gastrointestinal bleeding of 2 days' duration. Computed tomography of the abdomen showed a diffusely infiltrating bulky mass in the body and tail of the pancreas. The fine needle aspirate showed moderate to high cellularity, monotonous cell population, single ceil predominance over small cell clusters, and eccentrically located nuclei. Although the definite diagnosis of ICN on the cytologic basis is difficult, the cytomorphologic features are sufficiently distinctive to suggest the diagnosis.

• Journal of Gastric Cancer
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• 제11권4호
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• pp.234-238
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• 2011

A 67 year old male at a regular checkup underwent esophagogastroduodenoscopy. On performing esophagogastroduodenoscopy, a lesion about 1.2 cm depressed was noted at the gastric angle. The pathology of the biopsy specimen revealed a well-differentiated adenocarcinoma. On performing an abdominal computed tomography (CT) scan & positron emission tomography-computed tomography (PET-CT) scan, no definite evidence of gastric wall thickening or mass lesion was found. However, lymph node enlargement was found in the left gastric and prepancreatic spaces. This patient underwent laparoscopic assisted distal gastrectomy and D2 lymph node dissection. On final examination, it was found out that the tumor had invaded the mucosal layer. The lymph node was a metastasized large cell neuroendocrine carcinoma with an unknown primary site. The patient refused chemotherapy. He opted to undergo a close followup. At the postoperative month 27, he had a focal hypermetabolic lesion in the left lobe of the liver that suggested metastasis on PET-CT scan. He refused to undergo an operation. He underwent a radiofrequency ablation.

• Imaging Science in Dentistry
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• 제49권3호
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• pp.201-208
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• 2019

Purpose: The aim of this study was to evaluate the characteristic features of oral and maxillofacial swellings that could be seen on ultrasonographic examinations. Materials and Methods: Fifty patients with oral and/or maxillofacial swellings were randomly selected, thorough case histories and clinical examinations were done, ultrasonographic examinations with Doppler imaging were performed, and the features of every group were studied. Finally, histopathological evaluations were performed to identify the final diagnosis, according to which patients were classified into 5 groups; group I: inflammatory/space infection and abscess swellings, group II: cystic swellings, group III: lymph node swellings, group IV: benign swellings, and group V: malignant neoplastic swellings. Results: A significant association (P<0.05), with a contingency coefficient of 0.88, was found between the histopathological and ultrasonographic diagnoses, with ultrasonography having a diagnostic accuracy of 89% in diagnosing maxillofacial swellings. The diagnostic accuracy of ultrasonography was 100% for lymph node and malignant swellings, followed by 98% for inflammatory and cystic swellings and 92% for benign swellings. The sensitivity of the ultrasonographic diagnosis was 100% for cystic, lymph node, and malignant swellings, followed by 91% for inflammatory swellings and 86% for benign swellings. Conclusion: Ultrasonographic features with Doppler imaging greatly aid in obtaining accurate diagnoses of oral and maxillofacial swellings. Ultrasonography is a recommended imaging tool for differentiating maxillofacial swellings and classifying them accurately.

• Journal of Yeungnam Medical Science
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• 제38권3호
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• pp.245-250
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• 2021

Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a self-limiting lymphadenitis. It is a benign disease mainly characterized by high fever, lymph node swelling, and leukopenia. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease with clinical symptoms similar to those of KFD, but it requires a significantly more aggressive treatment. A 19-year-old Korean male patient was hospitalized for fever and cervical lymphadenopathy. Variable-sized lymph node enlargements with slightly necrotic lesions were detected on computed tomography. Biopsy specimen from a cervical lymph node showed necrotizing lymphadenitis with HLH. Bone marrow aspiration showed hemophagocytic histiocytosis. The clinical symptoms and the results of the laboratory test and bone marrow aspiration met the diagnostic criteria for HLH. The patient was diagnosed with macrophage activation syndrome-HLH, a secondary HLH associated with KFD. He was treated with dexamethasone (10 mg/m²/day) without immunosuppressive therapy or etoposide-based chemotherapy. The fever disappeared within a day, and other symptoms such as lymphadenopathy, ascites, and pleural effusion improved. Dexamethasone was reduced from day 2 of hospitalization and was tapered over 8 weeks. The patient was discharged on day 6 with continuation of dexamethasone. The patient had no recurrence at the 18-month follow-up.

• 대한골관절종양학회지
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• 제16권2호
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• pp.69-73
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• 2010

목적: 사지에 발생된 편평 상피암이나 악성 흑색종에서 술 중 소속 림프절 생검의 의미에 대해 알아보고자 한다. 대상 및 방법: 2005년 9월부터 2009년 1월까지 본원에서 악성 흑색종 또는 편평상피세포암으로 진단된 환자 중, 원발 부위의 광범위 절제술을 시행한 이후 술 후 면역항암화학요법을 시행하고 1년 이상 추시가 가능하였던 악성 흑색종 15예, 편평상피암 10예, 총 25예를 대상으로 하였고, 이 중 소속 림프절 생검을 시행한 군은 10예였다. 평균 연령은 64세였으며, 남자 15예, 여자 10예였다. 결과: 총 25예의 3년 생존율은 100%였고, 3년 무병 생존율는 76%였다. 총 6예에서 전이가 발생하였고, 서혜부 림프절 4예, 슬부 주위 연부조직 1예, 좌측 아킬레스건 1예였다. 소속 림프절 절제술을 시행하지 않았던 15예에서는 평균 생존율은 93.3%였고, 무병 생존율은 73.3%였다. 소속 림프절 절제술을 시행한 10예에서 평균 생존율은 100%였고, 무병 생존율은 90%였다. 술 중 소속 림프절 절제술을 시행한 10예 중 단 1예에서만 조직검사 상 양성 소견을 보였고, 소속 림프절 절제술을 시행하였던 10예 모두에서 추시 상 전이는 없었다. 소속 림프절 절제술 이후 합병증이 발생한 경우는 없었다. 결론: 소속 림프절의 생검 및 절제는 과거의 전 림프절 절제술과 비교하여 간단하고 적은 합병증으로 높은 정확도를 보이며, 종양의 정확한 병기 설정으로 치료 방향을 결정하는 것이 환자의 생존율을 높이는데 도움을 줄 수 있다고 판단된다.

• Journal of Gastric Cancer
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• 제4권3호
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• pp.186-191
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• 2004

Primary small-cell carcinomas of the stomach are rare and aggressive malignancies with poor survival rates. Preoperative diagnosis is difficult and a standard treatment is not yet established. We have recently experienced two cases of a primary small-cell carcinoma of the stomach. The first case was a 65-year-old man with epigastric soreness. Endoscopic biopsy showed an adenocarcinoma. He underwent a radical subtotal gastrectomy with D2 lymph-node dissection. Pathology revealed a collision tumor of a smallcell carcinoma and an adenocarcinoma with submucosal invasion and with metastasis in 20 out of 48 lymph nodes (T1N3M0). The second case was a 64-year-old man with epigastric soreness. Endoscopic biopsy revealed a small-cell carcinoma. There was no evidence of a primary tumor in the lung. A radical subtotal gastrectomy with D2 lymph-node dissection was performed. Pathology showed a pure smallcell carcinoma with proper muscle invasion and with metastasis in 1 out of 36 lymph nodes (T2aN1M0).

• Tuberculosis and Respiratory Diseases
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• 제41권6호
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• pp.644-650
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• 1994

어머니가 Stage 2 폐유육종증으로 진단 받고 치료된 후 4년만에 친 딸에서 X선상 폐문종대와 전방 포도막염이 발생하여, 기관지 폐생검 및 종격동경으로 실시한 종격동 임파선 생검으로 유육종증으로 진단된 가족형 유육종증이 우리나라에서는 처음 발견되어 문헌 고찰과 함께 보고하는 바이다.

• 대한방사선기술학회지:방사선기술과학
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• 제29권2호
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• pp.75-81
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• 2006

과거 유방암 환자에서 대부분을 수술로 불필요한 액와림프절 절개술을 하였지만, 그 결과로 부작용이 발생하였다. 본 논문에서는 유방암 환자에게 $^{99m}Tc-Tincolloid$를 이용하여 수술 전 유방림프절 검사를 먼저 시행한 뒤 처음 나오는 전초림프절을 영상화한 뒤 전초림프절의 전이 여부에 따라 수술범위를 달리 결정함으로써 환자의 수술 시간 및 수술 후의 부작용 최소화가 목적이다. 논문의 실험 결과는 실험대상 20명의 환자 중 15명에서는 액와림프절 절개술을 시행하지 않아도 되기에 수술로 인한 부작용을 줄일 수 있다. 그러나 아직까지 표준방법, 즉 방사성의약품 주사부위, 방사선량, 주사량, 마사지여부, 림프신티그라피 시행여부 등이 결정되지 않았으므로, 환자에 대한 고통경감과 부작용을 최소화 하고 수술부위를 최소화하기 위해서는 유방암 림프절검사법이 유용할 것이라 생각된다. 실험의 대상이 되는 환자는 초음파, 유방촬영술, 생검에서 유방암 진단을 받고 수술할 예정인 환자 20명으로, 환자의 연령 범위는 $31{\sim}71$세로 평균 연령은 45.4세이며, 임상 병기 I이 9명, 임상병기 II가 11명이다. 실험 장비로는 전초림프절을 묘출시켜주는 추적자로 $^{99m}Tc-Tincolloid(Amesham)$과 전초림프절의 위치를 찾는 장비로 Micro Probe : Neoprobe 2000(이하 감마 프로브), 영상 묘출 장비로 MS-II Gamma Camera : SIEMENS (이하 MS-II Gamma Camera)가 사용되었다. 실험 방법은 3가지 방법을 사용하며, 그 중 하나를 선택해 전초림프절 검사 및 수술실에서 감마프로브를 이용하여 생검을 실시한 결과의 20명 모두에서 전초림프절을 영상화 했다. 그리고 감마프로브로 전초림프절을 찾아 조직 생검 결과 20명 중에서 전초림프절의 전이가 발견된 환자는 5명이다. 본 실험에서 전이가 발견된 환자 5명을 다시 액와림프절을 생검한 결과의 3명에서 액와림프절 전이가 발견되었다.