• Title/Summary/Keyword: Lycoperdon perlatum

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Inhibition of Topoisomerase-mediated DNA Cleavage by Lycoperdon perlatum (말불버섯 추출물의 Topoisomerase 저해 효과)

  • Park, Mi-Jung;Cho, Kang-Jin;Kim, Jung-Bong;Kim, Dong-Hern;Kim, Yang-Sub;Seok, Soon-Ja;Kim, Sun-Yeou;Hwang, Young-Soo
    • Korean Journal of Food Science and Technology
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    • v.29 no.5
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    • pp.1057-1062
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    • 1997
  • In the course of searching for anticancer agents from 32 mushrooms, it was found that methanol extract of Lycoperdon perlatum showed inhibitory effect on topoisomerase II-mediated DNA cleavage. This active methanol extract was sequentially fractionated with hexane, chloroform, n-buthanol and water. Among the solvent-fractionated extracts, $1\;{\mu}g/mL$ hexane fraction of L. perlatum inhibited on topoisomerase II-mediated DNA cleavage. The effect of hexane fraction of L. perlatum was dose- and reaction time-dependent. The hexane fraction of L. perlatum was found to have inhibitory activity on relaxation assay of DNA topoisomerase I. The hexane fraction of cultured L. perlatum, however, had no inhibitory effect on either type of topoisomerase.

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The Screening of Antifungal and Antibacterial Activities of Extracts from Mushrooms in Korea (II) (한국산 버섯추출물의 항진균 및 항세균활성 검색(II))

  • Min, Tae-Jin;Kim, Eun-Mi;You, Sun-Hoo
    • The Korean Journal of Mycology
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    • v.24 no.1 s.76
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    • pp.25-37
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    • 1996
  • Antifungal and antibacterial activities of 108 extracts from 36 species of mushrooms in Korea were screened. The powder of fruiting body of each mushroom was extracted with petroleum ether, 80% ethanol and distilled water subsequently. Among these, five extracts including the ethanol extract of Agaricus subrutilescens, seven extracts including the water extract of Amanita virosa, nine extracts including the water extract of Amanita pantherina and twenty five extracts including the water extract of Lycoperdon perlatum showed antibiotic activities against yeasts, fungi, Gram-negative bacteria and Gram-positive bacteria, respectively.

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Relationship between Macrofungi Fruiting and Environmental Factors in Songnisan National Park (속리산 국립공원의 버섯발생과 환경요인과의 관계)

  • Park, Yong-Woo;Koo, Chang-Duck;Lee, Hwa-Yong;Ryu, Sung-Ryul;Kim, Tae-Heon;Cho, Young-Gull
    • Korean Journal of Environment and Ecology
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    • v.24 no.6
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    • pp.657-679
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    • 2010
  • Mushroom fruiting was investigated in pine and oak dominated forest stands in Songni National Park located in central Korea for six years from 2003 to 2008, in order to understand the relationship between mushroom diversity and the environmental factors, precipitation, temperature, soil moisture and vegetation. The most frequent fruiting families were those of ectomycorrhizal mushrooms, Tricholomataceae, Amanitaceae, Russulaceae, Cortinariaceae, and Boletaceae. The frequency of mushroom fruiting varied from 94 to 167 species per year, with July and August having the highest(13~90 species). Mushroom fruiting was positively correlated to precipitation(r=0.897), using Palmer Drought Severity Index for the long term period and Standard Precipitation Index for short term period. Soil moisture content also affected mushroom fruiting, with Lactarius chrysorrheus and Russula virescens fruiting only at soil moisture content higher than 20%. Positive correlation between mushroom fruiting and temperature was also noted(r=0.77), with optimum rates at $21{\sim}25^{\circ}C$. Tricholoma flayayirens, Amanita gymnopus, Lactarius piperatus, Inocybe asteropora and Xerocomus chrysenteron were able to fruit at temperatures higher than $25^{\circ}C$. However, Laccaria amethystea, Amanita virosa and Russula mariae fruited at relatively wide temperature range. The influence of vegetation on mushroom fruiting was likewise noted, with 38 species, including Suillus bovinus and Boletopsis leucomelas being specific to pine dominated stands, while 42 species, including Polyporus arcularius and Hericium erinaceum were specific to oak dominated stands. On the other hand, around 50 species, including Laccaria laccata and Lycoperdon parlatum, were able to fruit in both types of vegetation. In conclusion, mushroom fruiting greatly varies with changes in precipitation, soil moisture, temperature and vegetation.