• 한방안이비인후피부과학회지
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• 제17권2호
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• pp.140-145
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• 2004

Systemic lupus erythematosus is a disease of unknown etiology that affects many organ system and is characterized by the presence of multiple autoantibodies that participated in immunology mediated tissue injury. A 36 years-old female patient was admitted to ward due to high fever and erythematous rash on face and hole body. She exhibited itching sense, joint pain, nausea, fatigue, sensitivity to light. The homatologic finding revealed anemia, decrease of lymphocyte, low platelet count, but LE cell, Anti nuclear antibody(ANA) were negative. In the point of Differentiation of Syndrome(辨證), SLE can be thought to be a category of Seasonal febril disease(溫病). This subject diagnosed as Domination of intense evil heat(熱毒熾盛), and was administrated with Chungonpadocyem-gamibang(淸瘟敗毒飮加味方). The clinical and laboratory findings of our patient were improved by herb medication, acupuncture therapy and general supportive measure.

• Journal of Yeungnam Medical Science
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• 제35권2호
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• pp.227-231
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• 2018

Left main coronary artery (LMCA) thrombosis is rare and the cause should be determined. A previously healthy young man presented with severe chest pain and dyspnea. The electrocardiogram showed typical ST-segment elevation myocardial infarction with clinical instability. Emergency coronary angiography revealed complete LMCA occlusion by thrombosis. After reperfusion, the patient was admitted to the cardiac care unit. He was diagnosed with hemolytic anemia and tested positive for antinuclear antibodies. Systemic lupus erythematosus (SLE) and LMCA disease due to systemic thrombosis were diagnosed. Steroids were started and the patient was discharged without complications. We report this rare case of LMCA thrombosis as an initial presentation of SLE.

• 대한수의학회지
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• 제61권1호
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• pp.1.1-1.5
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• 2021

A 5-year-old neutered female Dachshund dog presented with a 3-month history of hyperthermia, skin lesions, and shifting lameness. Based on physical examination, blood tests, urinalysis, and radiographs, the dog was diagnosed with systemic lupus erythematosus. Clinical signs improved after administration of prednisolone and cyclosporine but relapsed after the prednisolone was reduced due to side effects. Oral levamisole was commenced and the other immunosuppressants were tapered over a period of 2 months and then stopped. Levamisole was retained as the sole therapy for an additional 2 months. Six months after discontinuation of all treatment, the patient remained in remission.

• Clinics in Shoulder and Elbow
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• 제24권3호
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• pp.178-182
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• 2021

A 50-year-old woman who had been previously diagnosed with systemic lupus erythematosus consulted our clinic for pain and weakness in her right shoulder. On examination, she had an atrophied deltoid muscle, a painful right shoulder on movement, and a tender mass in the deltoid area. The patient was diagnosed with corticosteroid-induced deltoid myopathy, shoulder pain, and loss of range of motion that did not resolve with conservative treatment. We decided to perform reverse shoulder arthroplasty. No complications were observed at the last follow-up visit at 3 years postoperative. Unlike deltoid insufficiency that results from axillary nerve injury, deltoid myopathy due to corticosteroid use contains intact fibers,. Therefore, we increased the effectivity of the remaining deltoid fibers by extending the moment arm of the anterior fibers using reverse shoulder arthroplasty and achieved reliable improvements in clinical symptoms and function without increasing the risk of dislocation.

• ETRI Journal
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• 제45권4호
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• pp.594-602
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• 2023

Internet of things (IoT) is commonly employed to detect different kinds of diseases in the health sector. Systemic lupus erythematosus (SLE) is an autoimmune illness that occurs when the body's immune system attacks its own connective tissues and organs. Because of the complicated interconnections between illness trigger exposure levels across time, humans have trouble predicting SLE symptom severity levels. An effective automated machine learning model that intakes IoT data was created to forecast SLE symptoms to solve this issue. IoT has several advantages in the healthcare industry, including interoperability, information exchange, machine-to-machine networking, and data transmission. An SLE symptom-predicting machine learning model was designed by integrating the hybrid marine predator algorithm and atom search optimization with an artificial neural network. The network is trained by the Gene Expression Omnibus dataset as input, and the patients' data are used as input to predict symptoms. The experimental results demonstrate that the proposed model's accuracy is higher than state-of-the-art prediction models at approximately 99.70%.

• 대한족부족관절학회지
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• 제28권1호
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• pp.36-39
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• 2024

Lupus panniculitis is a rare disease that may present with similar clinical manifestations to an infection, such as cellulitis or abscess. This paper reports a case of a 25-year-old woman with systemic lupus erythematosus who underwent surgical intervention initially with the suspicion of an abscess but who was eventually diagnosed with lupus panniculitis. Despite the low incidence of lower leg involvement of panniculitis, clinicians should be aware of the possibility of an etiology other than infection when encountering patients with inflammatory diseases. Moreover, a skin biopsy and magnetic resonance imaging with a diffusion-weight image may be helpful.

• Childhood Kidney Diseases
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• 제28권2호
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• pp.80-85
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• 2024

Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare entity characterized by the presence of lupus anticoagulant (LA) and prothrombin (factor II) deficiency. It may cause severe bleeding contrary to classical antiphospholipid syndrome. Here, we report a case of LAHPS presenting with a hemorrhagic ovarian cyst in a 17-year-old girl with systemic lupus erythematosus (SLE) nephritis. She had been followed up for 8 years. Her first manifestation of SLE was prolonged gingival bleeding after tooth extraction at 9 years of age. During the follow-up period, she had neither severe bleeding nor thrombotic complications despite a positive LA and a prolonged activated partial thromboplastin time (aPTT). At this visit, the patient presented with colicky abdominal pain, a hemorrhagic ovarian cyst, a prolonged prothrombin time, a prolonged aPTT, a low factor II level, and a positive LA, leading to the diagnosis of LAHPS. While a hemorrhagic ovarian cyst resolved completely in 3 months, she received oral pill, transfusions of red blood cells and plasma, and intravenous cyclophosphamide pulse therapy in combination with glucocorticoids due to persistent menorrhagia, anemia, prolonged aPTT, and lupus flaring. Thus, LAHPS needs to be considered in SLE patients with positive LA and prolonged aPTT.

• Clinical and Experimental Pediatrics
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• 제48권3호
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• pp.342-345
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• 2005

저자들은 전신성 홍반성 루푸스 산모에서 출생한 생후 1개월된 신생아에서 매우 드물게 나타나는 항-$U_1RNP$ 항체 양성으로 인한 신생아 홍반성 루푸스 1례를 경험하였기에 그 임상적 특징을 문헌고찰과 함께 보고하는 바이다.

• 기본간호학회지
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• 제8권3호
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• pp.324-333
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• 2001

Purpose: A quasi-experimental study was conducted to identify the effects on Self-efficacy, Fatigue, Coping Skills and Self-care Activities by Korean patients following a Systemic Lupus Erythematosus Self-Management (SLESM) Course. Methods : A two group pre-test and post-test design was used. The participants in the study were forty-one people with Systemic Lupus Erythematosis of which 21 subjects were assigned to the experimental group and 20 to the control group The experimental group received six weekly 2-hour group sessions, while the control group did not receive any intervention Outcome measures included self-efficacy, fatigue, coping skills and self-care activities. Baseline demographic and clinical variables did not differ between the two groups. Results : Patients who Participated in the self-management course showed significant decrease in fatigue (p= .038), improvement in self-efficacy (P= .001) and coping skills (p= ,048), increase in self-care activities (p= .003), and in the number of types of self-care activities(P= .048). Conclusion: Self-efficacy, coping skills and self-care activities improved and fatigue was reduced following the SLESM course. This study showed that a SLESM course is a good nursing intervention that can be offered in community settings.

• Tuberculosis and Respiratory Diseases
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• 제50권6호
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• pp.732-739
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• 2001

교원성 질환에 병발하여 나타나는 간질성 폐렴은 여러가지가있으며, 이 중 비특이성 간질성 폐렴은 통상성 간질성 폐렴과는 달리, 예후가 좋고 스테로이드에 반응이 좋은 질병이다. 저자들은 전신성 홍반성 낭창에 동반된 비특이성 간질성 폐렴환자를 경험하고, 스테로이드를 써서 치료 후 외래에서 추적 관찰하는 1예가 있었기에 문헌 고찰과 함께 보고하는 바이다.