• Tuberculosis and Respiratory Diseases
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• 제65권4호
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• pp.313-317
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• 2008

저자들은 기침, 우측 흉부 불쾌감을 주소로 내원한 58세 남자 환자에서 기관지내시경 육안 소견상 양성 종양이 의심 되었으나 조직 검사상 지방종을 확진하지 못하였고 악성 종양을 배제할 수 없는 상황에서 종괴에 의한 우중엽과 우하엽의 허탈 및 폐쇄성 폐렴 때문에 수술적 치료를 시행하였으며, 수술 결과 기관지 지방종에 의한 폐허탈과 함께 폐쇄세기관지기질화 폐렴이 발생한 예가 있어 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제44권5호
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• pp.1132-1139
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• 1997

기관지에서 점액상피양 종양은 드문 병변으로 대부분은 임상적으로 양성 경과를 보이는 저등급 암종이나 때로는 치명적인 고등급 암종을 보일 수 있으며 치료는 병리학적 등급에 관계없이 외과적 절제가 우선이다. 저자들은 호흡곤란을 내원하여 우폐 전체의 허탈 소견을 보인 임신 32주의 여자에서 조직학적으로 확인되어 수술한 저등급의 점액 상피양암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제26권3호
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• pp.209-213
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• 1993

The pathogenesis of the primary spontaneous pneumothorax is the rupture of subpleural bleb or bullae and subsequent sudden collapse of the affected lung. Mostly, the bullae or blebs are present bilaterally, but detecting the number, size, and location of the causating foci by plain chest film is quite difficult . We have performed chest CT scans for detecting the bullous lesions in 33 cases of primary spontaneous pneumothorax, and compared the results with surgical findings.1. Seventy-four blebs were identified in the chest CT scan, and 100 blebs or bullae were detected surgically [ Sensitivity was 0.74 ].2. Diagnosis rate was 80% [40/50] at right upper lobe, 75.7% [28/37] at left upper lobe, 55.6% at right lower lobe, and 25.0% at left lower lobe, respectively.3. Blebs or bullae smaller than 1 cm of its diameter were detected by 57.1% [24/42] of sensitivity, and in the cases of size larger than 1 cm, it revealed 86.2% [50/58] of sensitivity respectively.4. Of the 45 cases, 7 cases were false negative [15.6%], most of these were ruptured or small size [< 0.5 cm]. 5. One case was false positive, which was irregular adhesion at the apex of the lung.6. We could detect blebs or bullae with preoperative CT scans in 84.4% [38/45] of total patients. In conclusion, chest CT scan is a very advantageous diagnostic tool for proper management and preventing recurrence of primary spontaneous pneumothorax patient.

• 한국동물위생학회지
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• 제41권1호
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• pp.51-55
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• 2018

Herein, we report a case of badgers showing high morbidity and mortality rate due to the mixed infection of canine distemper virus (CDV) and Streptococcus canis (S. canis) in a farm where wild animal, badger, is being reared for herbal medicine. During the period of about one month, 120 out of 320 badgers showed severe respiratory symptoms and died, and 3 bodies were submitted to the Animal and Plant Quarantine Agency for disease diagnosis. The lung with the most severe necropsy findings failed to collapse and showed dark reddening and had yellowish nodules on the cut surface. The characteristic and common histopathologic findings include multifocal necrosis with hemorrhage of the lung, severe lymphoid depletion of the spleen and intracytoplasmic or intranuclear inclusion bodies in almost all organs. Finally, CDV and S. canis were identified by immunohistochemistry and bacterial isolation, respectively. This is the first mixed infection case of CDV and S. canis in badgers being raised on the farm.

• Journal of Chest Surgery
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• 제23권3호
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• pp.572-576
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• 1990

A complete transection of left main bronchus was repaired by end to end anastomosis 5 months after the chest trauma in the Yeungnam University Hospital. The patient was a 36 years old male who had been injured bluntly by a heavy package on the left chest. The initial symptoms and signs were dyspnea, chest pain and subcutaneous emphysema on the left neck, but on admission at our hospital his chief complaint was only mild left chest discomfort. The preoperative chest X-ray findings 5 months after the trauma revealed total collapse of the left lung, deviation of trachea to the left, elevation of left diaphragm, abrupt discontinuation in the course of an air-filled left main bronchus and bronchoscopy showed that the left main bronchus was completely occluded, without any signs of inflammation, approximately 4 cm from the carina. The operation was performed through standard posterolateral thoracotomy incision at the fifth intercostal space. There was not any suppuration within the transected lung but plenty of white mucus which was removed by forceful suction. The transected bronchial edges were debrided and anastomosed primarily by end to end with interrupted nonabsorbable sutures. The suture line was reinforced with a pleural flap. The postoperative course was uneventful and pulmonary function following operation improved progressively and proved the delayed repair to have a reasonable decision.

• The Korean Journal of Physiology and Pharmacology
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• 제17권4호
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• pp.267-274
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• 2013

A beneficial radioprotective agent has been used to treat the radiation-induced lung injury. This study was performed to investigate whether curcumin, which is known to have anti-inflammatory and antioxidant properties, could ameliorate radiation-induced pulmonary inflammation and fibrosis in irradiated lungs. Rats were given daily doses of intragastric curcumin (200 mg/kg) prior to a single irradiation and for 8 weeks after radiation. Histopathologic findings demonstrated that macrophage accumulation, interstitial edema, alveolar septal thickness, perivascular fibrosis, and collapse in radiation-treated lungs were inhibited by curcumin administration. Radiation-induced transforming growth factor-${\beta}1$ (TGF-${\beta}1$), connective tissue growth factor (CTGF) expression, and collagen accumulation were also inhibited by curcumin. Moreover, western blot analysis revealed that curcumin lowered radiation-induced increases of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), TNF receptor 1 (TNFR1), and cyclooxygenase-2 (COX-2). Curcumin also inhibited the nuclear translocation of nuclear factor-${\kappa}B$ (NF-${\kappa}B$) p65 in radiation-treated lungs. These results indicate that long-term curcumin administration may reduce lung inflammation and fibrosis caused by radiation treatment.

• 대한수의학회지
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• 제7권2호
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• pp.25-30
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• 1967

Pathological studies, on the lung of 27 cases of bovine parasitic bronchitis which were secured from abattoirs in Korea, were performed and discussed. The chief pathological findings were as follows. Grossly, the lungs were shown various degree of lobular consolidation, collapse and alveolar emphysema around the bronchi in which nematodes of Dictyocaulus viviparus were present. Emphysema and edema were observed in the interlobular septa. The lesions were encountered mostly in the caudal and ventral borders of the diaphragmatic lobes. In all the cased of parasitic bronchitis in which thickening of the visceral pleura and fibrinous deposition on the pleural surfaces were not seemed to be entirely due to the lungworm infection. Microscopically, bronchopneumonia, peribronchial and peribronchiolar lymphoid hyperplasia, lympho-reticular broncho-occlusive legion, and bleakthrough lesion were examined in the affected lungs.

• Journal of Chest Surgery
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• 제18권4호
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• pp.835-839
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• 1985

Spontaneous pneumothorax is the sudden collapse of a lung usually caused by air leaking from a sub-visceral pleural bleb. Response to closed thoracotomy, needle aspiration and simple observation is usually prompt and effective. But in some cases, these are unsuccessful and open thoracotomy is indicated. Author reviewed 37 cases of open thoracotomy in spontaneous pneumothorax experienced in the Dept. of Thoracic and Cardiovascular Surgery, Pusan National University Hospital, since Jan., 1980 to Dec., 1984. The results were as follows: 1. The causes of spontaneous pneumothorax: 73.0% was primary, 27.0% was secondary origin. 2. The most frequent age group of the patient: Between 11 and 30 years old. 3. All of te patient were male. 4. The side of open thoracotomy: 58.8% was right side, 8.8% was both side. 5. The most common indication of open thoracotomy; Persistent air leakage. 6. The most frequent sites of bleb or bullae: A-P segment in the L.U.L. and apical segment in the R.U.L.

• 한국임상수의학회지
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• 제29권1호
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• pp.78-81
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• 2012

5세 수컷 포인터견이 만성 기침 증상으로 내원하였다. 기관지내시경 검사에서 좌측 폐엽으로 분지하는 기관지 내강은 점액농성 삼출물과 함께 70% 이상 허탈된 상태로 관찰되었으며, 주기관 내강에서는 점액성 결절들이 확인되었다. 컴퓨터 단층촬영 검사는 좌측 폐엽으로 주행하는 기관지의 허탈을 재확인하게 하였다. 해당 검사결과들을 근거로, 환자는 만성기관지염과 함께 기관지연화증이 발병한 것으로 진단되었다. 본보는 만성기침을 보이는 대형견에서 기관지연화증을 진단한 증례이며, 기관지내시경검사는 기관지연화증의 발생 유무를 평가할 수 있는 중요한 검사법임을 보여준다.

• Journal of Chest Surgery
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• 제42권3호
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• pp.355-360
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• 2009

배경: 양성 기형종은 대부분은 무증상이지만 적은 빈도에서 늑막, 심외막, 폐실질, 기관지 내로 파열 되어 심한 증상 유발과 함께 치료가 어려워 술 전 파열여부에 대한 정확한 진단이 수술적 치료에 있어서 중요하다. 따라서, 이 연구에서는 파열된 양성 기형종의 임상적 증상, 영상학적 소견과 수술적 소견에 대해서 알아보고 파열되지 않은 기형종과의 차이를 알아 보고자 하였다. 대상 및 방법: 24명의 완전 절제된 양성 기형종의 환자를 후향적으로 조사하였다. 수술 전 임상 증상, 흉부 CT 소견, 수술 소견과 수술 성적의 차이를 파열된 군과 파열되지 않은 두 군에서 비교하였다. 특히 흉부 CT 소견에서는 종괴 크기, 피막 두께, 종괴의 위치, 분엽 정도, 균일성, 종괴 내용물, 주위 장기와의 관계 등을 조사하였다. 결과: 총 24명의 환자에서 수술 소견 결과, 7명의 환자(29.2%)가 파열된 양성 기형종으로 진단되었다. 15명(62.5%)의 환자에서 술 전 흉통, 기침 등의 증상이 있었으며 파열된 양성 기형종에서 증상이 심하고 빈도가 높았으나 통계적으로 차이는 없었다(p=0.37). 흉부 CT 소견에서는 두 군간에 종괴의 크기, 피막 두께, 종괴의 위치, 분엽정도, 균일성에는 차이가 없었다. 하지만 석회화 정도와(p=0.04), 종괴 주변 소견으로 폐경화, 폐허탈의 빈도가 파열 양성 기형종에서 통계적으로 유의하게 높았다(p=0.03). 파열된 양성 기형 종에서 수술적 접근은 모두 흉골 절개 또는 개흉술을 통해서 이루어 졌으며 동반된 폐절제 건수도 많았다. 결론: 술 전 흉부 CT는 파열된 기형종을 정확하게 진단할 수 있었고, 종괴 내에 석회화가 존재하거나 폐병변이 동반된 경우 파열된 기형종의 확률이 높았다. 따라서, 술 전 임상 소견 및 흉부 CT 소견에 의한 정확한 진단은 적절한 수술적 시기를 정하거나 접근 방법을 정하는 데에도 중요한 역할을 할 것으로 생각된다.