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Cadiorespiratory effects of isoflurane-anesthetized dogs with closed chest during spontaneous two-lung and one-lung ventilation (마취된 개의 자발호흡상태에서 일측폐환기 및 양측폐환기가 심순환기 및 호흡기계에 미치는 영향)

  • Song, Young-sung;Chang, Hwa-seok;Kim, Hye-jin;Kim, Soon-shin;Choi, Joon-chul;Yang, Hee-taek;Chung, Dai-jung;Kim, Hwi-yool
    • Korean Journal of Veterinary Research
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    • v.45 no.2
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    • pp.279-285
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    • 2005
  • One-lung ventilation (OLV) is the isolation and selective ventilation of one lung field. OLV allows the collapse of lung lobes on the side of the thoracic surgical approach to facilitate observation of intrathoracic structures and to achieve lung immobility. OLV be achieved by endotracheal intubation with double lumen tubes or bronchial blockers. In this study, cardiopulmonary consequences of two-lung ventilation (TLV), OLV and Re-TLV (TLV after OLV) were evaluated in 5 dogs. The dogs were anesthetized with mask induction and maintained with isoflurane in oxygen. Tidal volume and respiratory rates were set to maintain end-tidal $CO_2$ at $40{\pm}2mmHg$ during instrumentation. Following instrumentation, the dogs were placed in right lateral recumbency and induced spontaneously respiration state. Effect of TLV on hemodynamic and pulmonary variables were recorded. Then, the left bronchus was obstructed by endotracheal intubation with double lumen endotracheal tube to achieve OLV state and recording was continued. After OLV, double lumen endotracheal tube was extubated, and standard endotracheal tubes was intubated again. In this study, spontaneous OLV caused significant decrease in $PaO_2$, arterial oxygen saturation, mixed-venous oxygen saturation, and increase in $PaCO_2$. Especially, a significant elevation in $PaCO_2$ and respiratory acidosis were remarkable findings. So spontaneous ventilation in OLV affected gas exchange and hemodynamic function.

EFFECTS OF LOCAL IRRIGATION AND/OR INTRAVENOUS ADMINISTRATION OF ARGATROBAN ON THROMBOSIS IN MICROVASCULAR ANASTOMOSES OF FEMORAL VEIN OF RABBIT (가토대퇴정맥에서 미세혈관문합시 Argatroban의 국소세척 및 전신투여가 혈전형성에 미치는 영향)

  • Kook, Min-Suk;Park, Hong-Ju;Oh, Hee-Kyun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.31 no.4
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    • pp.300-305
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    • 2005
  • Purpose: For the reconstruction of maxillofacial defect created by trauma, infection, or tumor etc, the role of microvascular anastomosis or vessel graft has been increased. Many methods has been tried to increase the success rate of microvascular anastomosis. Various anticoagulants and thrombolytic agents have been used to reduce the failure rate of microvascular anastomosis and avoid re-operation. Many drugs, however, have been used in the limited cases because most of these drugs may cause complications, such as allergy, fever or systemic bleeding. This study was performed to evaluate the influence of the Argatroban on patency and thrombosis in microvascular anastomosis when it is used for local irrigation or general administration. Materials & methods: Eight mature rabbits, weighing 2kg, were used. After exposing both femoral veins, the artificial thrombotic model was made by crushing injury using a smooth needle holder, and the transverse incision were made on femoral vein. The animals were divided into 4 groups according to Argatroban administration methods; control group (n=4), topical irrigation of lumen with saline solution; experimental group 1 (n=4), topical irrigation of lumen with Argatroban saline solution; experimental group 2 (n=4), topical irrigation of lumen with heparin followed by intravenous injection of Argatroban; experimental group 3 (n=4), topical irrigation of lumen with Argatroban followed by IV of Argatroban. Microvascular anastomosis was done with 10-0 Ethilon. The patency was evaluated by empty-and-refill test 30 minutes and 3 days after microanastomosis. The thrombus formation was examined 3 days after microanastomosis by surgical microscope. The histologic findings were also examined. Results: 1. Thirty minutes after microvascular anastomosis, the patency of all experimental groups was better than that of control group, but there was no significant difference among groups. 2. Three days after microvascular anastomosis, the patency of all experimental groups was more improved than that of control group (p<0.05). There was no significant difference among experimental groups. 3. Three days after microvascular anastomosis, the amount of thrombus in all experimental groups was less than that of control group (p<0.05). There was no significant difference among experimental groups. 4. Histologically, a lot of luminal thrombus was observed around sutured area in control group. Few luminal thrombus was observed in all experimental groups. The necrotic changes were observed on the sutured vein wall in all specimens. Conclusion: These results indicate that topical irrigation and/or intravenous administration of Argatroban is effective in improving patency and preventing thrombus formation after microvascular anastomosis.

Usefulness of ultrasonography radial artery diameter with lumen evaluation (초음파를 이용한 요골동맥의 직경 및 내강 평가)

  • Park Young-Hee
    • Journal of The Korean Radiological Technologist Association
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    • v.27 no.2
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    • pp.175-180
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    • 2001
  • Ⅰ. Background and Objectives : Recently the percutaneous transradial approach for coronary angiography and angioplasty has been using. When the radial artery as a graft for coronary artery bypass surgery was used, pantency increased. Many examination and

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Ultrasonographic Evaluation of the External Ear Canal in Dogs (개에서 외이도의 초음파학적 평가)

  • 이해운;엄기동;성윤상;이정민;이종원;김정은;장광호;이근우;장동우
    • Journal of Veterinary Clinics
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    • v.21 no.2
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    • pp.149-153
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    • 2004
  • This study was to determine the procedure for ultrasonographic imaging of the canine external ear canal(ECC). By infusion of warm saline solution into the ear canal, a real-time B mode ultrasonographic examination of the ECC was performed in five healthy Beagle dogs and two dogs with severe otitis externa. The ultrasonography was very useful to detect the structures of the ECC and the tympanic membrane. An 11 NHz linear probe was permitted to assess an anechoic lumen of the ECC and a hyperechoic cartilage surrounding the ear canal. In two dogs with otitis externa, it could be assessed the ECC with ultrasonography without ear cleansing. A lumen of the ECC was irregular and a cerumen could be seen, but edematous inflammatory changes of the ECC could not be identified. The results suggest that ultrasonography of the ECC with an 11 NHz linear probe after infusing the saline solution into the ear canal may be an accurate, non-invasive, rapid, and widely available method for assessment of the ear canal diseases such as otitis externa, polyp, stenosis, hyperplasia, and foreign body in dogs.

Chemical Properties of Artificially Buried Wood in an Intertidal Zone during the Deterioration Period

  • SEO, Sujin;KIM, Taekjoon;LEE, Jae-Won
    • Journal of the Korean Wood Science and Technology
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    • v.48 no.6
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    • pp.896-906
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    • 2020
  • Wood deterioration experiments were carried out for 6 months in an intertidal zone of South Korea to monitor the changes in the chemical properties of two types of species, Korean red pine and sawtooth oak. The results of FT-IR spectra and XRD patterns have shown that the chemical properties of the wood did not change significantly during the 6-month burial period. However, the brightness of the surface decreased after burial; the value of the sawtooth oak sample was lower than that of the Korean red pine sample owing to an accumulation of inorganic compounds in cell lumen as observed by ICP analysis. Among the inorganic compounds, sodium and sulfur concentrations increased significantly over the burial period compared with the control. Further, the maximum moisture content decreased from 199% to 136% in the Korean red pine and 62% to 60% for the sawtooth oak. Nevertheless, the major chemical composition of both the wood species did not change significantly during the 6-month burial period, whereas, the crystallinity decreased with an increasing burial period owing to an accumulation of inorganic compounds in the lumen.

The Effect of Low Molecular Weight Heparin on Groin Flap Transplantation in Rat (저분자량 헤파린이 쥐 서혜부 유리피판 이식술에 미치는 영향)

  • Lee, Jun-Mo;Lee, Gang-Wook;Lee, Dong-Geun
    • Archives of Reconstructive Microsurgery
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    • v.2 no.1
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    • pp.77-81
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    • 1993
  • Free tissue transplantation is commonly performed with the brilliant achievement in microsurgery and anticoagulants and antithrombotic agents have been prescribed in the procedures. However, there is no clean-cut indication as to which agents would be more effective in every steps and final consequences. Low molecular weight heparins inhibiting coagulation in plateletrich plasma and acting on the vascular endothelium have antithrombotic and fibrinolysis action. The experiment with rat groin free flap transplantation after 6-hour ischemia and injection of the low molecular weight heparin was performed and the results between the injection and non-injection group were analysed as follows, 1. Both of the 24-hour groups, vessel patency was not proportional to color change of the groin flap. 2. On the second day after anastomois, heparin-injection group showed intact intima, patent lumen without thrombus, and mild granulomatous inflammation around the suture material and control group with doubtful patency revealed intimal loss and thrombus formation. 3. On the 5th, 7th, and 9th postoperative day, heparin group was patent in anastomosis and showed acute inflammatory cells. 4. The 7th-week period, heparin-injection group showed intact flap color, patent lumen with intact intima and persistent foreign body granuloma.

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A Comparison Study Between International Standard and Statistical Analysis on LED Package Life (국제표준과 통계적 분석을 통한 LED Package 수명 비교 연구)

  • Park, Se Il;Kim, Gun So;Kim, Chung Hyeok
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.31 no.2
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    • pp.122-127
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    • 2018
  • In an attempt to estimate the life projection of LED packages, IESNA published a paper regarding an LED package measurement test method in 2008, and a life projection technical document in 2011, to be used for LED life estimation. IESNA's publications regarding LED package measurement methods were functional, but they were not internationally standardized before 2017. In order to develop a standardized method, the International Standard chose to use the LM-80 as a measurement method for LED life projection in their publication in 2017. Many projection methods have been discussed by the IEC Technical Committee 34 working group, including the method using an exponential function, which reflects lumen degradation characteristics well. This study is designed to explore alternative LED package life estimation methods using an exponential function with statistical analysis, other than the one suggested by the International Standard.

Use of Intraluminal Sutureless Graft in the Surgical Treatment of Dissecting Aneurysm(Debakey type III) of the Thoracic Aorta (무봉합 혈관내 인조혈관을 사용한 박리성 하행흉부대동맥류의 치료 -2례 보고-)

  • 홍순필
    • Journal of Chest Surgery
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    • v.27 no.10
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    • pp.862-867
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    • 1994
  • We experienced two cases of dissecting aneurysm[DeBakey type III] of the thoracic aorta treated using intraluminal sutureless graft. Controversy still exists about the exact timing of surgical intervention for dissection of the descending thoracic aorta. The surgical indication of dissecting aneurysm[DeBakey type III] is continuous flow in the false lumen, continuous chest pain, compromise of arterial supply to a specific organ or limb, or extension of the dissection while the patient is receiving satisfactory medical treatment. Surgical therapy for dissection of the aorta has had a high mortality. One contributing factor has been hemorrhage from the prosthesis and the suture lines. Recently, a new method of treatment with a intraluminal sutureless graft that requires no end-to-end anastomosis has been developed. In our cases, cardiopulmonary bypass and circulatory arrest was utilized in repairing dissecting aneurysm of descending aorta[DeBakey type III] in order to avoid the aortic cross clamping because of friable aortic intima. The basic technique consists of vertical incision of descending aorta in the area of intimal tear and inserting the whole ringed graft into the true lumen of the dissected aorta and circumferentially ligating the aorta against the groove in the rings. Postoperative course was uneventful.

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Laparoscopic Transabdominal Transfer of Blastocysts in Korean Black Goats

  • Cho, Sang-Cheol;Cho, Jong-Ki;Shin, Sang Tae
    • Journal of Embryo Transfer
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    • v.32 no.2
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    • pp.47-52
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    • 2017
  • As a part of the effort to improve post-transfer survival rate of embryos in Korean black goats, a technique for laparoscopic uterine transfer of blastocysts was carried out. A total of 26 transferrable embryos (morula to expanded blastocysts) were transferred to 13 recipient goats via transabdominal laparoscopic method. In consequence of our hormone protocol, 65% of the recipients (13/20) were found to have synchronized estrus. After confirmation of corpus luteum in each recipient goat, a Babcock laparoscopic forceps was inserted into the lower abdominal cavity to hold a uterine horn and fasten it near the peritoneum without causing injury. Then 7.5cm long 16G IV catheter was inserted directly into the uterine lumen through the abdominal wall. After removal of the stylet of the IV catheter, the embryo transfer tube (identical in size to the stylet and loaded with blastocysts) was inserted into the uterine lumen through the catheter to unload the embryos. Of the 13 estrus synchronized recipients, 9 were transferred blastocysts and 4 were transferred molurae (2 embryos in each recipient) in uterine ipsilateral to the ovary with corpus luteum. Four of the 9 recipients which blastocysts were transferred using this method has been confirmed pregnant (44.4% pregnancy rate).

Liquid-liquid extraction process for gas separation from water in polymeric membrane: Mathematical modeling and simulation

  • Salimi, Nahid;Moradi, Sadegh;Fakhar, Afsaneh;Razavi, Seyed Mohammad Reza
    • Membrane and Water Treatment
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    • v.7 no.5
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    • pp.463-476
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    • 2016
  • In this study, application of polypropylene hollow fiber membrane contactors for $CO_2$ removal from water in liquid-liquid extraction (LLE) mode was simulated. For this purpose, a steady state 2D mathematical model was developed. In this model axial and radial diffusion was considered to $CO_2$ permeation through the hollow fibers. $CO_2$ laden water is fed at a constant flow rate into the lumen side, permeated through the pores of membrane and at the end of this process, $CO_2$ solution in the lumen side was extracted by means of aqueous diethanolamine (DEA) and chemical reaction. The simulation results were validated with the experimental data and it was found a good agreement between them, which confirmed the reliability of the proposed model. Both simulation and experimental results confirmed the reduction in the percentage of $CO_2$ removal by increment of feed flow rate.