• 제목/요약/키워드: Lower Body Obesity

검색결과 717건 처리시간 0.021초

A ketogenic diet reduces body weight gain and alters insulin sensitivity and gut microbiota in a mouse model of diet-induced obesity

  • Sumin Heo;Soo Jin Yang
    • Journal of Nutrition and Health
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    • 제56권4호
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    • pp.349-360
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    • 2023
  • Purpose: Ketogenic diets (KDs) have anti-obesity effects that may be related to glucose control and the gut microbiota. This paper hypothesizes that KD reduces body weight and changes the insulin sensitivity and gut microbiota composition in a mouse model of diet-induced obesity. Methods: In this study, C57BL/6 male mice were assigned randomly to 3 groups. The assigned diets were provided to the control and high-fat (HF) diet groups for 14 weeks. The KD group was given a HF diet for 8 weeks to induce obesity, followed by feeding the KD for the next 6 weeks. Results: After the treatment period, the KD group exhibited a 35.82% decrease in body weight gain compared to the HF group. In addition, the KD group demonstrated enhanced glucose control, as shown by the lower levels of serum fasting glucose, serum fasting insulin, and the homeostatic model assessment of insulin resistance, compared to the HF group. An analysis of the gut microbiota using 16S ribosomal RNA sequencing revealed a significant decrease in the proportion of Firmicutes when the KD was administered. In addition, feeding the KD reduced the overall alpha-diversity measures and caused a notable separation of microbial composition compared to the HF diet group. The KD also led to a decrease in the relative abundance of specific species, such as Acetatifactor_muris, Ligilactobacillus_apodemi, and Muribaculum_intestinale, compared with the HF group. These species were positively correlated with the body weight, whereas the abundant species in the KD group (Kineothrix_alysoides and Saccharofermentans_acetigenes) showed a negative correlation with body weight. Conclusion: The current study presents supporting evidence that KD reduced the body weight and altered the insulin sensitivity and gut microbiota composition in a mouse model of diet-induced obesity.

도시지역 초등학생 비만 수준 및 관련 요인에 대한 연구 -사회경제적 요인을 중심으로- (Study on the Relationship between Childhood Obesity and Various Determinants, including Socioeconomic Factors, in an Urban Area)

  • 강희태;박경희;권영준;임형준;백도명;이현주;주영수
    • Journal of Preventive Medicine and Public Health
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    • 제39권5호
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    • pp.371-378
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    • 2006
  • Objectives: This study was conducted to investigate the prevalence of childhood obesity, the association between the undesirable lifestyles and socioeconomic factors, the association between childhood obesity and various risk factors, including socioeconomic factors, and the agreement between the body mass index (BMI) classification and the body fat percentage. Methods: The study subjects were all the 5th grade students from all the elementary schools in Gunpo City, Kyunggi Province, South Korea (4043 children at 22 schools). The subjects were measured for their height, weight and percent body fat etc. and they were also surveyed by questionnaire from March 18th to April 25th, 2005. To determine whether the children were within normal limits or not, standardized BMIs for each age group were used. The data was analyzed by logistic regression analysis using SAS 9.0 version. Results: The prevalence of childhood obesity prevalence was 25.1 %. Boys had a higher prevalence of obesity (27.5%) than did the girls (22.5%). Children had tendencies of having undesirable lifestyles and getting obese if they had a lower socioeconomic status. The risk factors for childhood obesity were low paternal education (OR: 1.17, 95% CI : 0.97-1.42) and non-parental caregivers (OR: 1.34, 95% CI : 0.98-1.82). Other risk factors for childhood obesity were a high birth-weight, longer TV/computer-using time, a lower fruit-eating frequency, short sleeping hours and parental obesity. The agreement rate between the BMI classification and the body fat percentage was 93.1 %. Conclusions: This study showed the children had a higher prevalence of obesity: further, not only individual lifestyles, but also socioeconomic factors could influence childhood obesity. Childhood obesity was especially more problematic for children with a low socioeconomic status.

학령기아동의 체형분류법에 따른 체중, 키, 비만도 및 체질량지수 비교 (Comparison in Weight, Height, Degree of Obesity and Body Mass Index Among Different Methods for Body Shape Classification in School-Age Children)

  • 안영미;손민;최선하
    • 대한간호학회지
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    • 제40권6호
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    • pp.775-784
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    • 2010
  • Purpose: The study was conducted to describe body shapes of school age children using the degree of obesity index (DOI) and body mass index obesity index classified by the Ministry of Education, Science and Technology (M-BOI) and Seoul Metropolitan Office of Education (S-BOI). Methods: In this cross sectional descriptive study health screening data for school children collected in 2007 was used. Results: Data were analyzed for 2,193 4th-6th grade boys (52%) and girls who attended 4 schools in rural areas. DOI determined that only 44.3% of students had average weight. This proportion was much lower than the results of other methods (74.3-77.6%). All three methods defined girls (51.3-61.8%) as skinnier than boys. Skinny and average body shaped children classified by DOI and obese children classified by S-BOI were heavier and taller and presented higher degrees of obesity (DO) and BMI scores than by other methods. M-BOI and S-BOI presented statistically significant positive correlations with weight, height, DO and BMI, while DOI was not correlated with height. Conclusion: BMI based body shape classifications provide a more rigorous classification of body shape which are favorable for school health professionals with limited resources and policy makers for internationally comparable references.

성인 비만 여성 체형의 유형별 특성에 관한 연구

  • 최혜선;이진희
    • 대한인간공학회:학술대회논문집
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    • 대한인간공학회 1996년도 춘계학술대회논문집
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    • pp.201-211
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    • 1996
  • This study was carried out on 132 obese women who satisfied both of the conditions for obesity : over 1.6 in Roher index and over 90cm in bust girth. The purpose of the study was to classify body shape of obese women and find out their respective characteristics. 1. The characteristics on shape of body measurements are the front of waist height was higer than the back of waist height due to the obesity in abdominal region and the front of the abodominal depthe was high indicating the protruding of the abdominal region. 2. Characteristics of different obese body types 1) In the study of total body type, 5 factors were found as a result of factor analsis and body types were classified 4 types (type 1: short upper torso and obese arms and legs, type 2: Long and thick torso, type 3: the most obese torso, arms and legs, type 4: less obese torso according to the cluster analysis. 2) The torso body types were coassified 2 groups (type 1: less obese than average body type, type 2: large in all girth, depth and breadth according) to the different body parts such as back lengh, bust girth, hip girth and acromion to acromion breadth. 3) The lower body types were classified 2 groups (type 1: short legs, less the depth and breadth, type 2: large in all lower body measurenents) according to back of waist height, waist girth and hip girth.

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Attenuated Sympathetic Activity and Its Relation to Obesity in MSG Injected and Sympathectomized Rats

  • Park, So-Young;Kim, Yong-Woon;Dan, Jin-Myoung;Kim, Jong-Yeon
    • The Korean Journal of Physiology and Pharmacology
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    • 제11권4호
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    • pp.155-161
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    • 2007
  • In order to characterize the role of sympathetic activity in obesity, we repeatedly assessed sympathetic activity via power spectral analyses of heart rate variability in the same subjects at 7, 11, 25, and 60 weeks, using monosodium glutamate (MSG)-induced obese and control rats. The effects of lower sympathetic activity on obesity were also evaluated. Fat mass in MSG rats was already higher at 7 weeks, but the sympathetic activity did not differ between 7 and 25 weeks. Between 25 and 60 weeks, the increase in fat mass, food efficiency, and body weight gain was higher in MSG rats. The increase in sympathetic activity between 25 and 60 weeks and sympathetic activity at 60 weeks were lower in MSG rats. Fat mass at 60 weeks was inversely correlated with changes in sympathetic activity between 25 and 60 weeks. Reduced plasma epinephrine levels by bilateral adrenal demedullation induced increase of fat mass. In, an attenuated increase of sympathetic activity with age may partly be responsible for aggravated obesity in MSG rats. Additionally, reduced sympathetic activity per se induced obesity in rats. These results suggest that lower sympathetic activity contributes to obesity in rats.

Plus-size 성인여성의 의복패턴 설계를 위한 상반신 체형 연구 (An Analysis of Upper-Body Shapes in Obese Women for Apparel Pattern Design)

  • 윤지원;윤혜준;안재상
    • 한국의류산업학회지
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    • 제15권1호
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    • pp.130-137
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    • 2013
  • The percentage of overweight people has increased in older people due to the change of body shape (including pregnancy and giving birth for women). Obesity is accompanied by body shape changes; subsequently, there are more pattern design considerations compared to standard body shapes. This paper classifies the upper body shape of overweight women in Korea, analyzes features by body shape and proposes basic pattern design data that reflects the features of plus-size women body shapes. The data on 540 subjects in the overweight group (from 20 to 69 years old)whose BMI was over 25 was selected. The following features by shape were identified in accordance with the upper body shape classification of overweight women. Body Shape1 had lower body obesity with long stature and arms in proportion to the trunk length and represented 22.2% of the subjects. Body Shape2 had most parts near average sizes for overweight body shapes with short height and arms that represented 37.6% of the subjects (the highest ratio). Body Shape3 was the smallest body shape in the four groups with the most distinct body figure and represented 30.7% of the subjects. Body Shape4 (9.4% of the subjects)was the upper body obesity type (the fattest group)and with of the waist bigger abdominal obesity type.

운동용 속옷의 착용효과 -부위별 체지방의 변화를 중심으로- (The Wearing Effect of Sport Underwear -Focusing on the Change of Fat in Each Body-)

  • 나미향;김미선;정복희
    • 복식문화연구
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    • 제10권6호
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    • pp.735-747
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    • 2002
  • This study aimed at investigating the change of fat in each body part according to the wearing of sport underwear made of specially-processed materials. in this study. 6 females made up of three early twenties, and three later thirties took part in the exercises for 12 weeks to to out the change of fat amount in body, square of body part by CT and obesity after and before an exercise. The results are as follows: In the obesity condition after and before an exercise, Roller's index shows that in case of 51 and 54, one level was lowered concerning the basic physical strength and optimal index was not changed. In the silhouette between body frames. there are differences between ages. The body fat rate decreased 35.95% on the average. and the amount of the body fat of females in twenties was more than that in thirties. The amount of body fat decrease with the lapse of exercising time, while the amount of body fat shows increased of 0.75%, which showed the minus correlation. The rate of averaged flat by CT went up after an exercise in every body part. and also the decreased value of subcutaneous fat was not proportioned to that of weight and girth. Inbody parts, the lower abdomen was shown 49.7%, navel part 47.7% and waist part 37.3% each in numerical value. In the thickness of subcutaneous fat concerning waist, the value of front-center line was the lowest, and followed by rear-center line and lateral line. 1204degree part in the navel showed the most fat layed, and the lowest fat layed was in the lateral part. Concerning the lower part of abdomen, under-skin fat was the most layed in 120degree part like that of navel part.

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도시지역 여자고등학생들의 체형과 체형에 대한 의식 및 자각증상과의 관계 (Body Types and Its Relation with the Body Type Awareness, and Subjective Symptoms of Female High School Students in an Urban Area)

  • 류광하;권인선;김형선;조영채
    • 한국학교보건학회지
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    • 제21권2호
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    • pp.13-22
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    • 2008
  • Purpose : This study investigated the relationship between body type, subjective symptoms and health awareness in female high school students Methods : The subjects were 393 students at the female high school in Taejon City by self-recorded questionnaires in May, 2006. Results : In the classification of body type based on the degree of obesity, low weight group was 20.9%, normal weight group was 58.0%, over weight group was 11.7% and obesity group was 9.4%. In the level of body type wareness, those who consider themselves to be obesity type 13.7%, standard type were 43.8%, and leptosomic type 8.1%, but there was a clear tendency to be leptosomic type that the rate was 76.3%. In the complaint rates of subjective symptoms, “fatigue” was the highest, followed by “neck pain(stiffness)”, “dizziness”, “stomachache” in the descending order. In the complaint rates of subjective symptoms by the degree of obesity, dizziness, irregular menstruation and anorexia were higher according to the lower obesity, but constipation and wearied eyes were the higher the more obesity. Conclusion : The study results showed that the recent female high school students were clear tendency to be leptosomic type, and leptosomic and obesity type were related with subjective symptoms. Considering these findings, it appeared that being excessively thin is related to symptoms and young women's thinness-oriented attitudes are unhealthful.

마황포황탕이 비만생쥐의 비만유전자 및 관련인자에 미치는 영향 (Effects of Mahwangpohang-tang on the Expression of Obesity-Related Genes and Cytokines in Obesity Mice)

  • 송인선;송태원;오민석
    • 동의생리병리학회지
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    • 제19권4호
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    • pp.1055-1061
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    • 2005
  • In this study, the aim was to investigate the effect of Mahwangpohang-tang on the expression of obesity-related genes and cytokines in high fat diet induced obesity mice. In order to investigate the effects of Mahwangpohang-tang(MHPH) on the obesity-related genes and cytokines, C57BL/6 mice were fed with high fat diet. C57BL/6 mice were divided into three groups and fed for 13weeks. Body weight change, diet intake change, final increase of body weight, the ratio of the adipocyte in body weight, the expression of leptin gene in primary adipocytes, the expression of UCP-2 in primary adipocytes, the production change of $TNF-\alpha$ and leptin in primary adipocytes, the expression of leptin in adipocytes tissue. The body weight of Mahwangpohang-tang(MHPH) intake mice was significantly lower than high fat diet group. The amount of the adipocyte in body weight was decreased Significantly. In primary adipocytes, leptin gene expression and the expression of UCP-2 did not change significantly. In primary adipocytes, the amount of $TNF-\alpha$ was significantly decreased at dose of $100{\mu}/ml$ density. In adipocytes tissue, the expression of leptin did not change significantly. These results suggest that MHPH may inhibit the expression of obesity-related genes and cytokines in high fat diet induced obesity mice

Validity of Self-Reported Height, Weight, and Body Mass Index of the Korea Youth Risk Behavior Web-Based Survey Questionnaire

  • Bae, Ji-Suk;Joung, Hyo-Jee;Kim, Jong-Yeon;Kwon, Kyoung-Nam;Kim, Yoon-Jung;Park, Soon-Woo
    • Journal of Preventive Medicine and Public Health
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    • 제43권5호
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    • pp.396-402
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    • 2010
  • Objectives: Self-reported anthropometric values, such as height and weight, are used to calculate body mass index (BMI) and assess the prevalence of obesity among adolescents. The aim of this study was to evaluate the validity of selfreported height, weight, and BMI of the Korea Youth Risk Behavior Web-based Survey questionnaire. Methods: A convenience sample of 137 middle school students and 242 high school students completed a selfadministered questionnaire in 2008. Body height and weight were directly measured after self-reported values were obtained from the questionnaire survey. Sensitivity, specificity, and kappa statistics were computed in order to evaluate the validity of the prevalence of obesity (BMI $\geq$ 95th percentile or $\geq$ $25;kg/$m^2$) based on self-reported data. Results: Self-reported weight and BMI tended to be underestimated. Self-reported height tended to be overestimated among middle school females and high school males. Obese adolescents tended to underestimate their weight and BMI and overestimate their height more than non-obese adolescents. The prevalence estimate of obesity based on selfreported data (10.6%) was lower than that based on directly measured data (15.3%). The estimated sensitivity of obesity based on self-reported data was 69.0% and the specificity was 100.0%. The value of kappa was 0.79 (95% confidence interval, 0.70 - 0.88). Conclusions: This study demonstrated that self-reported height and weight may lead to the underestimation of BMI and consequently the prevalence of obesity. These biases should be taken into account when self-reported data are used for monitoring the prevalence and trends of obesity among adolescents nationwide.