• Title/Summary/Keyword: Low risk

Search Result 4,333, Processing Time 0.034 seconds

Controversies about Radioactive Iodine-131 Remnant Ablation in Low Risk Thyroid Cancers: Are We Near A Consensus?

  • Zaman, Maseeh Uz;Fatima, Nosheen;Padhy, Ajit Kumar;Zaman, Unaiza
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.11
    • /
    • pp.6209-6213
    • /
    • 2013
  • Well differentiated thyroid cancers (WDTC), including papillary (80%) and follicular (10%) types, are the most common endocrine cancers globally. Over the last few decades most the diagnosed cases have fallen into low risk categories. Radioactive iodine-131 (RAI) has an established role in reducing recurrence and improving the survival in high risk patients. In patients with primary tumor size <1 cm, RAI is not recommended by many thyroid societies. However, low risk WDTC has been an arena of major controversies, most importantly the role and dose of adjuvant RAI for remnant ablation to minimize chances of recurrence and improving survival. This review is an attempt to update readers about the previous and existing practice based on results of non-randomized trials and evolving trends fueled by recently published randomized studies.

- Analysis of Likelihood of Failure for the External Corrosion of Carbon and Low Alloy Steels through the Quantitative Risk Based Inspection using API-581 - (API-581에 의한 정량적 위험기반검사에서 탄소강 및 저합금강의 외부부식에 치한 사고발생 가능성 해석)

  • Lee Hern Chang;Kim Hwan Joo;Jang Seo Il;Kim Tae Ok
    • Journal of the Korea Safety Management & Science
    • /
    • v.6 no.4
    • /
    • pp.239-248
    • /
    • 2004
  • Likelihood of failure for the external corrosion of carbon and low alloy steels, which affect to a risk of facilities, was analyzed quantitatively through the risk based inspection using API-581 BRD. We found that the technical module subfactor (TMSF) decreased as the inspection number increased and it increased as the Inspection effectiveness and the used year increased. In this condition, the TMSF showed high value for the case of the marine/cooling tower drift area as a corrosion driver, poor quality of coating, no insulation, and low insulation condition.

The Influence of Consumers' Purchase Experience and Technology Readiness on Risk Perception and Satisfaction in Internet Clothing Shopping (소비자의 인터넷쇼핑 구매경험과 기술준비성이 인터넷 의류쇼핑시 위험지각과 만족도에 미치는 영향)

  • Hong, Keum-Hee
    • Fashion & Textile Research Journal
    • /
    • v.6 no.1
    • /
    • pp.93-101
    • /
    • 2004
  • The purpose of this study is to examine consumers' risk perception in internet clothing shopping and its relation with technology readiness and the frequency of purchase. Thereafter, this study examines how consumers' risk perception affect service quality and satisfaction at the apparel shopping sites. An on-line survey was made to collect data, and the replies from 785 people, who had an experience of apparel shopping on line, were used in data analysis. From factor analyses, risk perception comprised 3 factors of product related risk, delivery related risk, and security related risk, and technology readiness comprised 4 factors of optimism, innovativeness, discomfort, and insecurity. Based on cluster analysis, consumers were classified into 3 types in terms of the internet risk perception: low risk group, medium risk group, and high risk group. From path analysis, risk perception was decreased with high frequency of purchase and low discomfort and insecurity of technology readiness, and risk perception and service quality had an influence on consumers' satisfaction with the shopping sites.

A study on the quantitative risk grade assessment of initial mass production for weapon systems (초도양산 군수품에 대한 정량적 위험등급평가 방안 연구)

  • Jung, Yeongtak;Ham, Younghoon;Roh, Taegoo;Ahn, Manki;Ko, Kyungwa
    • Journal of Korean Society for Quality Management
    • /
    • v.46 no.3
    • /
    • pp.441-452
    • /
    • 2018
  • Purpose: The purpose of this paper is to study quantitative risk grade assessment for objective government quality assurance activities based on risk management in initial mass production for weapon systems. Methods: The Defense quality management regulations and foreign risk assessment documents are referred to analyze problems performing quality assurance actives. The failure rate data, maintainability and cost of products have been studied to quantify the risk Likelihood and impact. The analyzed data were classified as risk grade assessment through K-means Cluster Analysis method. Results: Results show that a proposed method can objectively evaluate risk grade. The analyzed results are clustered into three levels such as high, middle and low. Two products are allocated high, eleven low and seven middle. Conclusion: In this paper, quantitative risk grade assessment methods were presented by analyzing risk ratings based on objective data. The findings showed that the methods would be effective for initial mass production for weapon systems.

Design and Implementation of Road Construction Risk Management System based on LPWA and Bluetooth Beacon

  • Lee, Seung-Soo;Kim, Yun-cheol;Jee, Sung-Hyun
    • Journal of the Korea Society of Computer and Information
    • /
    • v.23 no.12
    • /
    • pp.145-151
    • /
    • 2018
  • While commercialization of IoT technologies in the safety management sector is being promoted in terms of industrial safety of large indoor businesses, implementing a system for risk management of small outdoor work sites with frequent site movements is not actively implemented. In this paper, we propose an efficient dynamic workload balancing strategy which combined low-power, wide-bandwidth (LPWA) communication and low-power Bluetooth (BLE) communication technologies to support customized risk management alarm systems for each individual (driver/operator/manager). This study was designed to enable long-term low-power collection and transmission of traffic information in outdoor environment, as well as to implement an integrated real-time safety management system that notifies a whole field worker who does not carry a separate smart device in advance. Performance assessments of the system, including risk alerts to drivers and workers via Bluetooth communication, the speed at which critical text messages are received, and the operation of warning/lighting lamps are all well suited to field application.

Feedback on Baseline Use of Staging Images is Important to Improve Image Overuse with Newly Diagnosed Prostate Cancer Patients

  • Sawazaki, Harutake;Sengiku, Atsushi;Imamura, Masaaki;Takahashi, Takeshi;Kobayashi, Hisato;Ogura, Keiji
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.4
    • /
    • pp.1707-1710
    • /
    • 2014
  • Background: The objective of this study was to evaluate baseline use and positive rates of staging images (bone scan, CT) in newly diagnosed patients with prostate cancer (PCa) and to improve staging image overuse. Materials and Methods: This retrospective study covered a consecutive series of patients with PCa who underwent stage imaging at our institution between 2006 and 2011. Various clinical and pathological variables (age, PSA, biopsy Gleason score, clinical T stage, positive biopsy core rate) were evaluated by multivariate logistic regression analysis for their ability to predict a positive staging image. All patients were stratified according to the NCCN risk stratification and positive rates were compared in each risk group. Results: 410 patients (100%) underwent a bone scan and 315 patients (76.8%) underwent a CT scan. Some 51 patients (12.4%) had a positive bone scan, clinical T3 and T4 being significant independent predictors. Positive bone scan rates for low-, intermediate-, high-, and very high-risk groups were 0%, 0%, 8.25%, and 56.6%. Some 59 (18.7%) patients had a positive CT scan, with elevated PSA and clinical T3, T4 as significant independent predictors. Low-, intermediate-, high- and very high-risk group rates were 0%, 0%, 13.8% and 80.0%. Conclusions: The incidences of positive staging image in low- and intermediate- risk group were reasonably low. Following feedback on these results, staging in low- and intermediate- risk groups could be omitted.

The Study of Consumer's Clothing Discount Store Selection Behavior by Their Price Attitude and Risk Perception (소비자의 가격태도와 위험지각에 따른 의류할인점 선택행동에 관한 연구)

  • 박은주;홍금희
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.23 no.4
    • /
    • pp.529-540
    • /
    • 1999
  • The purpose of this study is examine how price attitude and risk perception affect6 consumer's attitude to clothing discount stores. As for the methods of the research 313 female consumers who just finished shopping at discount stores were interviewed and questioned. The result is as the following. 1. The factors such as discount price inclination effective value inclination price-quality association and price-social grade association in the price attitude as well as social psychological risk and the risk of losing opportunity in the risk perception affected consumer's attitude to clothing discount store. 2. The domestic national brand discount store acquired the highest scores in all factors but discount inclination factor and low price inclination factor. No difference was seen between stores in terms of the risk perception. 3. The determining factors for repurchase intention were found to be store satisfaction and the attitude to clothing discount store. 4. The convenience of transportation the availability of exchange or repair the payment option the quality of the product and the attributes of the store e, g, good quality with relatively low price affected the store satisfaction. 5. Domestic national brand discount store showed higher score in 'good quality with relatively low price' than domestic casual brand discount store did. And difference between groups was found in repurchase intention, Conclusively most consumers using clothing discount stores are effective value-oriented.

  • PDF

Comparison of ASCUS and Human Papilloma Virus (미확정 편평상피세포와 인체 유두종바이러스와의 비교)

  • Park, Mi-Soon;Chang, Byoung-Soo
    • The Journal of the Korea Contents Association
    • /
    • v.13 no.8
    • /
    • pp.308-313
    • /
    • 2013
  • Among 179 specimen diagnosed with ASCUS but did not go through biopsy or other tests, 26 cases (14.52%) showed positivity in HPV Hybrid Capture II Test. There were 25 cases of HPV high risk factor(+), marking 13.96%, and 3 cases of low risk factor(+) at 1.67%. According to cytology manifestation, patients with over LSIL can increase their complete recovery rate with continuous tests, but most patients diagnosed ASCUS do not go through any tests at all. It is considered that in order to prevent and start early treatment on cervical cancer, the HPV Hybrid Capture II Test must be enforced to patients diagnosed with ASCUS. Negative patients should go through routine screening, and positive patients should receive treatment after colposcopy.

A prediction model of low back pain risk: a population based cohort study in Korea

  • Mukasa, David;Sung, Joohon
    • The Korean Journal of Pain
    • /
    • v.33 no.2
    • /
    • pp.153-165
    • /
    • 2020
  • Background: Well-validated risk prediction models help to identify individuals at high risk of diseases and suggest preventive measures. A recent systematic review reported lack of validated prediction models for low back pain (LBP). We aimed to develop prediction models to estimate the 8-year risk of developing LBP and its recurrence. Methods: A population based prospective cohort study using data from 435,968 participants in the National Health Insurance Service-National Sample Cohort enrolled from 2002 to 2010. We used Cox proportional hazards models. Results: During median follow-up period of 8.4 years, there were 143,396 (32.9%) first onset LBP cases. The prediction model of first onset consisted of age, sex, income grade, alcohol consumption, physical exercise, body mass index (BMI), total cholesterol, blood pressure, and medical history of diseases. The model of 5-year recurrence risk was comprised of age, sex, income grade, BMI, length of prescription, and medical history of diseases. The Harrell's C-statistic was 0.812 (95% confidence interval [CI], 0.804-0.820) and 0.916 (95% CI, 0.907-0.924) in validation cohorts of LBP onset and recurrence models, respectively. Age, disc degeneration, and sex conferred the highest risk points for onset, whereas age, spondylolisthesis, and disc degeneration conferred the highest risk for recurrence. Conclusions: LBP risk prediction models and simplified risk scores have been developed and validated using data from general medical practice. This study also offers an opportunity for external validation and updating of the models by incorporating other risk predictors in other settings, especially in this era of precision medicine.

Treatment results of the second-line chemotherapy regimen for patients with low-risk gestational trophoblastic neoplasia treated with 5-day methotrexate and 5-day etoposide

  • Kanno, Toshiyuki;Matsui, Hideo;Akizawa, Yoshika;Usui, Hirokazu;Shozu, Makio
    • Journal of Gynecologic Oncology
    • /
    • v.29 no.6
    • /
    • pp.89.1-89.8
    • /
    • 2018
  • Objective: Highly effective chemotherapy for patients with low-risk gestational trophoblastic neoplasia (GTN) is associated with almost a 100% cure rate. However, 20%-30% of patients treated with chemotherapy need to change their regimens due to severe adverse events (SAEs) or drug resistance. We examined the treatment outcomes of second-line chemotherapy for patients with low-risk GTN. Methods: Between 1980 and 2015, 281 patients with low-risk GTN were treated. Of these 281 patients, 178 patients were primarily treated with 5-day intramuscular methotrexate (MTX; n=114) or 5-day drip infusion etoposide (ETP; n=64). We examined the remission rates, the drug change rates, and the outcomes of second-line chemotherapy. Results: The primary remission rates and drug resistant rates of 5-day ETP were significantly higher (p<0.001) and significantly lower (p=0.002) than those of 5-day MTX, respectively. Forty-seven patients (26.4%) required a change in their chemotherapy regimen due to the SAEs (n=16) and drug resistance (n=31), respectively. Of these 47 patients failed the first-line regimen, 39 patients (39/47, 82.9%) were re-treated with single-agent chemotherapy, and 35 patients (35/39, 89.7%) achieved remission. Four patients failed second-line, single-agent chemotherapy and eight patients (17.0%) who failed first-line regimens were treated with combined or multi-agent chemotherapy and achieved remission. Conclusions: Patients with low-risk GTN were usually treated with single-agent chemotherapy, while 20%-30% patients had to change their chemotherapy regimen due to SAEs or drug resistance. The second-line regimens of single-agent chemotherapy were effective; however, there were several patients who needed multiple agents and combined chemotherapy to achieve remission.