• Title/Summary/Keyword: Low risk

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Prognostic Value of a Single Center Nutrition Screening Tool in Patients with Metastatic Cancer (전이암 환자에서 단일기관 영양검색 도구의 예후 가치)

  • Yoon, Sung Soo;Kim, Min Jin;Kim, Eun Hye;Lee, Jee Young;Yoon, Seong Woo
    • Journal of Korean Traditional Oncology
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    • v.24 no.2
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    • pp.1-11
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    • 2019
  • Objectives : We investigated whether a single center nutrition screening tool (Kyunghee Neo Nutrition Risk Screening, KNNRS) can predict survival in patients with metastatic cancer. Methods : We retrospectively reviewed data of inpatients with metastatic cancer from April 2016 to August 2019. Data on demographic and clinical parameters were collected from electronic medical records, and overall survival was estimated using the Kaplan-Meier method. Stepwise Cox regression analysis was used to determine factors associated with survival. Patients with a KNNRS score of 0 to 3 were classified as "no-risk", 4 to 10 as "low-risk", and 11 to 20 as "high-risk". Results : Total 105 patients were included in the study. According to nutritional screening at baseline, 25 patients (23.8%, median age 57.0) were classified as ""no risk"" group; 80 patients (76.2%, median age 68.5) as "low risk" group; No patients as "high risk" group. Predictors of survival were Eastern Cooperative Oncology Group Performance Status score of 3 or 4 (hazard ratio [HR] = 1.93; 95% confidence interval [CI] = 1.21-3.10), hemoglobin less than 10 g/dL (HR = 1.97; 95% CI = 1.25-3.10) and C-reactive protein more than 1.0 mg/dL (HR = 1.95; 95% CI = 1.21-3.13). Kaplan-Meier survival analysis showed significant differences in the survival between KNNRS groups: ""no risk"" group: 6.1 ± 1.4 months (95% CI = 3.37-8.83); ""low risk"" group: 3.4 ± 0.9 months (95% CI = 1.5-5.37). Conclusions : Nutritional status according to KNNRS wasn't significant predictor of survival for patients with metastatic cancer. Improvement of KNNRS score thresholds is needed.

A Study on the Environmental Professionals′ Risk Perception towards Some Pollution Issues (일부 환경 전문가들의 환경 위해성 인식도에 관한 연구)

  • 신동천;박종연;임영욱;김진용;장은아;박성은
    • Environmental Analysis Health and Toxicology
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    • v.14 no.4
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    • pp.175-187
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    • 1999
  • To investigate the risk perception of environmental issues, two consequtive surveys were conducted to environmental professionals using a standardized questionnaire from September to October in 1999. The number of subjects were 72 for the first survey and 68 for the second one. The questionnaire was consisted of items such as the degree of environmental pollution in Korea, risk perception of some issues on human health and ecosystem, and seriousness of the problems in the real situation in Korea. For the degree of environmental pollution in Korea, the average risk rating in the second test (7.4 point) was significantly higher than that in the first test (7.2 point). The risk perception on the general human health and ecosystem, and the seriousness in Korea situation were analyzed in the order of ′air pollution′, ′water pollution′,′soil contamination′,′waste′,′toxic chemical pollutants′,′food contamination′,′ocean contamination′, ′odor pollution′, and ′noise pollution′. Also ′toxic chemical pollutants′ problem was perceived to be the highest risk on general human health or ecosystem, and on present situation in Korea. ′Automotive vehicle exhaust′ problem was perceived to be the most severe environmental problems among specific 30 items. ′Industrial source air pollution′,′toxic air pollutants′, and ′domestic and industrial source pollutants to surface water′ were relatively severe environmental problems comparing to other problems. The pollution issues were classified into four categories by two aspects of perception; risk in general setting and seriousness in Korea situation. If the issues were highly serious in Korea and low risk perception in general setting then it is named "the Korea-specific group". Those that were all high score in two aspects, named "the Common group". Those that were all low in two aspects, named "the Nonsignificant group". And the issues were high risk perception in general setting and low seriousness in Korean situation, named "the Latent group".

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Effects of Easing LTV·DTI Regulations on the Debt Structure and Credit Risk of Borrowers

  • KIM, MEEROO;OH, YOON HAE
    • KDI Journal of Economic Policy
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    • v.43 no.3
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    • pp.1-32
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    • 2021
  • With CB data in South Korea, this study examines whether the credit risk of borrowers changes when the regulation on bank mortgage supply is relaxed. We analyze the effect of deregulation on LTV and DTI limits in the Seoul-metropolitan area in August 2014 with a difference-in-difference approach. We find that the probability of delinquency is lower in the Seoul metropolitan area after the deregulation than in other urban areas. The effect is noticeable among low-income and low-credit borrowers. We also find that borrowers change their debt structure to reduce the interest costs utilizing their improved access to bank mortgages. The findings suggest the necessity to consider the burden of the high interest costs of unsecured loans for debtors with low incomes and low credit ratings in designing housing finance regulations.

The Ownership of the Largest Family Blockholders and Korean Firm Risk

  • KIM, Hung Sik;CHO, Kyung-Shick
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.3
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    • pp.287-296
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    • 2021
  • This paper investigates the relationship between the ownership of the largest family blockholders and corporate risk. We also examine whether firms that belong to 30 main Chaebol groups lower corporate risk. We use panel analysis for companies listed on the Korea Exchange from 2005 to 2017. We use beta, volatility, and idiosyncratic risk as a proxy for corporate risk. We employ both the ownership of the largest family blockholders and firms that belong to 30 main Chaebol groups as a major independent variable. The results show that the ownership of the largest family blockholders is associated with low beta. In terms of the effects of the ownership of the largest family blockholders on beta, we find that a firm that belongs to the 30 main Chaebol group reinforces the lower beta. These results suggest that the ownership of the largest family blockholders and firms that belongs to 30 main Chaebol groups may be associated with low systematic risk in the Korean stock market. Our findings can provide meaningful information to investors and field officers who are interested in the relationship between firm risk and both the largest family blockholders' ownership and firms that belong to 30 main Chaebol groups.

Maternal Factors Associated with the Premature Rupture of Membrane in the Low Birth Weight Infant Deliveries (조기 파막 저체중아 분만의 관련 모성 요인)

  • Lee, Kang-Sook;Lee, Won-Chul;Meng, Kwang-Ho;Lee, Choong-Hoon;Kim, Soo-Pyung
    • Journal of Preventive Medicine and Public Health
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    • v.21 no.2 s.24
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    • pp.207-216
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    • 1988
  • Premature rupture of membrane is the most frequent cause of low birth weight infant delivery which increase the maternal and fetal morbidity and perinatal mortality. A retrospective case-control study was performed on 315 mothers who delivered low birth weight infants($\leq$2.5kg) with premature rupture of membrane and as control group 546 mothers who delivered normal birth weight infants(2.9-3.7kg) without premature rupture of membrane were chosen. The results obtained from this study were as follows: 1. The proportion of low birth weight infants due to premature rupture of membrane among all low birth weight infant deliveries was 14.5%, and this is equivalent to 1.1% among all deliveries. 2. The most significant maternal risk factor of low birth weight infant deliveries with premature rupture of membrane was infections on vagina, cervix and uterus during pregnancy. Compared with control, adjusted odds ratio was 7.61(95% confidence interval(CI) 1.88-30.88, p=0.004). Other significant maternal risk factors were the history of induced abortion, spontaneous abortion, and the experience of premature delivery. The risk ratios were 1.82, 2.07, 4.42, respectively. 3. Breech presentation did increase the risk of low birth weight infant delivery with premature rupture of membrane compared with control(Adjusted Odds ratio=2.66, 95% CI 1.35-5.26, p=0.005). 4. Mothers who had not taken antenatal care were having higher risk of low birth weight infant delivery with premature rupture of membrane against control(Adjusted odds ratio=1.73, 95% CI 1.19-2.53, p=0.004). These study results show that maternal factors such as the infection of genital organs during pregnancy, the history of induced abortion and breech presentation are significantly associated with the premature rupture of membrane in the low birth weight deliveries, and that most of these risk factors are controllable ones through proper antenatal cares.

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Analysis of Likelihood of Failure for the Brittle Fracture through Quantitative Risk Based Inspection using API-581 (API-581에 의한 정량적 위험기반검사에서 취성파괴에 의한 사고발생 가능성 해석)

  • Kim Tae-Ok;Lee Hern-Chang;Jang Seo-Il
    • Journal of the Korean Institute of Gas
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    • v.10 no.1 s.30
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    • pp.1-6
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    • 2006
  • To use pressurized facilities safely and effectively, a likelihood of failure (LOF) for the brittle fracture was analyzed quantitatively through the risk based inspection using API-581 BRD. We found that for the case of the low temperature/low toughness and the temper embrittlement, the technical module subfactor (TMSF) showed high value for the A impact curve, low temperature, and the no post weld heat treatment. But the risk didn't significantly change at the $855^{\circ}F$ embrittlement, and the LOF far the sigma phase embrittlement showed high value at low temperature of the high sigma.

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Estimation of Human Carcinogenic Potency (HCP) of Carcinogens in Risk Assessment and Management. (위해성 평가 및 관리에 있어서 발암물질의 인체발암능력 평가)

  • 이병무;김대영;김세기;김근종
    • Environmental Mutagens and Carcinogens
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    • v.19 no.1
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    • pp.39-45
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    • 1999
  • Human Carcinogenic Potency (HCP) can be estimated based on human daily exposure dose to carcinogen (Dh), body weight (Wh), 10% tumorigenic dose (TD10), and slope factor at TD10 (Q10) from 2-yr bioassay data. This approach is more relevant to humans generally exposed to low doses of carcinogens and can reduce more of extrapolation errors from high dose in animal experiments to low dose in humans than HERP (human exposure dose/rodent potency dose) proposed by Ames et al. (Science, 236, 271-280, 1987). TD50 and HERP have been routinely used to compare rodent carcinogenic potency and human carcinogenic potency, but those approaches have had limitations in extrapolation of high dose to low dose in humans. The advantages of HCP are to estimate human exposure dose (Dh) by human monitoring instead of environmental monitoring, to consider slope factor (Q10) which reflects the tendency of curve at low dose, and to use TD10 which represents much lower dose thant TD50 or HERP. HCP will be a useful parameter for the estimation of human carcinogenic potency in risk assessment and management of carcinogens.

The Short-Term Effect of Low-Quality Sellers' Voluntary Information Disclosure (제품에 대한 부정적 정보 공개의 단기적 효과에 대한 연구)

  • Huh, Seung
    • Journal of Convergence for Information Technology
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    • v.11 no.1
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    • pp.80-90
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    • 2021
  • This study examines whether, when, and how sellers with low-quality products can instantly enhance profitability by fully disclosing quality information. Our analytic model has found that a low-quality seller can increase demand even in the short run by voluntarily sharing the information about its quality, if he can sufficiently reduce perceived risk of buyers. Moreover, a low-quality seller's information disclosure may increase both the market's and the competitor's demand, depending on the level of perceived risk. The finding of this study is expected to provide meaningful implications to managers and policy makers on solving market dilemmas under information asymmetry.

Comparison of ASCUS and HPV Hybrid Capture II Test Results (미확정 편평 상피세포와 인체 유두종 바이러스와의 비교)

  • Park, Mi-Soon;Chang, Byung-Soo
    • Proceedings of the Korea Contents Association Conference
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    • 2012.05a
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    • pp.175-176
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    • 2012
  • 세포선별검사에서 ASCUS로 진단된 검체 중 F-UP이 진행되지 않은 검체 179건을 대상으로 HPV High risk factor, Low risk factor를 확인하기 위해서 Hybrid Capture II Test를 하였다. 결과 High risk factor 양성 및 Low risk factor 양성은 전체 179 cases 중 25 cases로 나타났으며, 전체 검체 중 약 15%에 해당되었다. 또한 전체 15%의 양성검체 중 High risk factor 양성은 87%에 해당되는 것을 확인하였다. 결론적으로 효과적인 검진 체계를 갖춘 나라에서도 자궁경부암의 예방이 완전히 해결되지 않고 있는 문제점이 있는 여건을 고려해 볼 때 추적 관찰이 용이하지 않은 경우를 대비해 자궁경부암으로 진행될 수 있는 precancerous lesion의 원인 인자인 HPV 존재 유무를 세포선별검사와 HPV Hybrid Capture II Test를 동시에 시행하는 것이 효과적이라고 사료된다.

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Tobacco Use, Beliefs and Risk Awareness in University Students from 24 Low, Middle and Emerging Economy Countries

  • Peltzer, Karl;Pengpid, Supa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.10033-10038
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    • 2014
  • The aim of this study was to determine the prevalence of tobacco use, beliefs and risk awareness and psychosocial correlates of tobacco use among university students in 24 low, middle and emerging economy countries. Using anonymous questionnaires, data were collected from 16953 undergraduate university students (mean age 20.9, SD=2.9) from 25 universities in 24 countries across Asia, Africa and the Americas. Results indicate that overall 13.3% of the university students were current tobacco users, 22.4% for men and 6.6% for women, ranging from 3.8% in Singapore to 32.5% in Cameroon. The risk awareness of the smoking lung cancer link was 83.6%, while the risk awareness of the smoking heart disease link was 46.5%. Multivariate logistic regression found that older age, male gender, having a wealthy family background, living in a low income country, residing off campus on their own, poor beliefs in the importance not to smoke, awareness of the smoking heart disease link, hit by a sexual partner, depressive symptoms, and substance use (binge drinking and illicit drug use) were associated with current tobacco use.