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http://dx.doi.org/10.15432/JKTO.2019.24.2.001

Prognostic Value of a Single Center Nutrition Screening Tool in Patients with Metastatic Cancer  

Yoon, Sung Soo (Department of Korean Internal Medicine, Korean Medicine Cancer Center)
Kim, Min Jin (Nutritional Support Team, Kyung Hee University Hospital at Gangdong)
Kim, Eun Hye (Department of Korean Internal Medicine, Korean Medicine Cancer Center)
Lee, Jee Young (Department of Korean Internal Medicine, Korean Medicine Cancer Center)
Yoon, Seong Woo (Department of Korean Internal Medicine, Korean Medicine Cancer Center)
Publication Information
Journal of Korean Traditional Oncology / v.24, no.2, 2019 , pp. 1-11 More about this Journal
Abstract
Objectives : We investigated whether a single center nutrition screening tool (Kyunghee Neo Nutrition Risk Screening, KNNRS) can predict survival in patients with metastatic cancer. Methods : We retrospectively reviewed data of inpatients with metastatic cancer from April 2016 to August 2019. Data on demographic and clinical parameters were collected from electronic medical records, and overall survival was estimated using the Kaplan-Meier method. Stepwise Cox regression analysis was used to determine factors associated with survival. Patients with a KNNRS score of 0 to 3 were classified as "no-risk", 4 to 10 as "low-risk", and 11 to 20 as "high-risk". Results : Total 105 patients were included in the study. According to nutritional screening at baseline, 25 patients (23.8%, median age 57.0) were classified as ""no risk"" group; 80 patients (76.2%, median age 68.5) as "low risk" group; No patients as "high risk" group. Predictors of survival were Eastern Cooperative Oncology Group Performance Status score of 3 or 4 (hazard ratio [HR] = 1.93; 95% confidence interval [CI] = 1.21-3.10), hemoglobin less than 10 g/dL (HR = 1.97; 95% CI = 1.25-3.10) and C-reactive protein more than 1.0 mg/dL (HR = 1.95; 95% CI = 1.21-3.13). Kaplan-Meier survival analysis showed significant differences in the survival between KNNRS groups: ""no risk"" group: 6.1 ± 1.4 months (95% CI = 3.37-8.83); ""low risk"" group: 3.4 ± 0.9 months (95% CI = 1.5-5.37). Conclusions : Nutritional status according to KNNRS wasn't significant predictor of survival for patients with metastatic cancer. Improvement of KNNRS score thresholds is needed.
Keywords
KNNRS; nutritional screening; nutritional status; metastatic cancer; cancer survival;
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