• 대한임상검사과학회지
• /
• 제43권1호
• /
• pp.26-31
• /
• 2011

The genotypes of Human Papilloma Virus (HPV) are important in the carcinogenesis of uterine cervical cancer. Diagnosis of uterine cervical cancer screening has been executed using Papanicolau method (Pap) and HPV DNA Chip method. We researched the interrelation of HPV DNA genotypes in single and multiple infections and analyzed the results of Pap and HPV DNA Chip tests at Gunsan Medical Center (GMC). The correlation analysis was surveyed on collected results from 599 patients who have been tested with both Pap and HPV DNA chip tests from November 2004 to May 2010 at GMC. The inconsistency between Pap and HPV DNA Chip tests was 41.1%. The HPV DNA Chip genotype related with high risk cases were type 16 (13.5%), type 52 (10.5%), type 58 (10.1%), and type 18 (3.4%). Those related with low risk cases were type 70 (8.9%), type 6 (1.7%), type 40 (1.2%), type 11 (1.3%), and other types (14.3%). Among the 195 cases of HPV positive status, 161 cases were associated with single infection; 108 (67.1%) cases were related with high risk genotype; 19 (11.8%) cases were low risk genotype; 31 (21.1%) cases were related with other types. 29 cases were associated with double infections; 23 (79.3%) cases were high risks; 5 (17.2%) cases were mixed high and low risks; 1 (3.5%) case was low risk.

• 대한임상독성학회지
• /
• 제2권2호
• /
• pp.116-122
• /
• 2004

Purpose: Several risk factors related with chronic complications and mortality related with liver injury of mushroom poisoning were reported. But, there were few reports about the long term outcomes. The aim was to evaluate the long term clinical outcomes in mushroom poisoning regarding the risk factors. Methods: Clinical data were reviewed and outcomes were evaluated with medical records and/or telephone interviews. The patients who had one or more risk factors such as markedly elevated aspartate aminotransferase (AST) or alanine aminotransferase (ALT), prolonged prothrombin time (PT) were classified into high risk group. Patients had no risk factor classified into low risk group. Results: From June 1989 to December 2003, nineteen mushroom poisoning patients admitted to Asan Medical Center, seven were male, and mean age was $58\pm9$ years old. All the patients accidentally ingested and the interval from ingestion to symptom onset was $9\pm4$ hours. There were four patients in high risk group, and fifteen in low risk group. In high risk group, peak AST was $2,263.3\pm1,303.0IU/L$most prolonged PT was $38.0\pm27.4\%$, and stuporous mental status was shown in one patient. In low risk group, laboratory values returned to the normal values but histological evaluation revealed specific features of toxic hepatitis on sixth hospital day. Chronic complications such as persistent or chronic hepatitis, mortality was not occurred during follow up period (from 10 months to 16 years) in both groups. Conclusion: Although the number of patients were small, there were no chronic complications or mortality related with liver injury after mushroom poisoning regardless risk factors of chronic complications and mortality.

• Parasites, Hosts and Diseases
• /
• 제55권2호
• /
• pp.203-206
• /
• 2017

The seroprevalence of human toxoplasmosis has been increasing in Korea, and it is controversial whether cats are an important infection source or not. This study was performed to evaluate the seroprevalence of Toxoplasma gondii infection in a high risk group (cat sitters) and to determine the possible importance of cats as an infection source in Korea. Risk factors, including the age, sex, and diet of cat sitters, their contact experience and contact frequency with stray cats, and origin, number, and outdoor activity of their pet cats, were analyzed using structured questionnaires. A total of 673 serum samples from people who have frequent contact with cats (high risk group) and 1,114 samples from general people (low risk group) were examined for specific IgG antibodies against T. gondii by ELISA. The results revealed that the overall seroprevalence of T. gondii infection was 7.4% (n=1,787). The seroprevalence among low risk group was 8.0% (89/1,114), whereas that among high risk group was rather lower 6.4% (43/673), though this difference was statistically not significant (P=0.211). Among the risk factors, only the outdoor activity of pet cats was important; people having cats with outdoor activities revealed 2 times higher seroprevalence than people having cats with only indoor activities (P=0.027). In conclusion, the seroprevalence of T. gondii was not significantly different between the high risk group and low risk group, and the importance of cats as a source of infection in Korea is questionable.

• 대한가정학회지
• /
• 제38권6호
• /
• pp.149-169
• /
• 2000

The purpose of this study was to examine the environmental characteristics of adolescents in low-income families, identify the high-risk & protective factors among environmental contexts surrounding adolescents, and investigate the relative importance of high-risk & protective factors to adolescents'psychological and behavioral adjustment separately. The present study was the primary research of developing prevention program for adolescents'deviant behaviors in low-income families. Subjects of this study consisted of 176 adolescents drawn from 8 social-welfare institutions in Chungbuk province. The pilot study was done to examine the applicability of survey instrument. Data were analyzed by the frequency, percentage, Pearson correlation, stepwise regression using SPSS/WIN program. The results were as followings: 1. There was statistically correlated with each other in environmental high-risk and protective factors except an housing environment. The results implies that environmental contexts itself surrounding adolescents in low-income families can be either high-risk factors or protective factors. 2. The adolescents in low-income families perceived that stresses from consumer and school environments were high-risk factors among other environmental contexts. 3. The adolescents in low-income families perceived that resources from friend and school were protective factors among other environmental contexts. 4. The stresses from friend and eating behaviors were significant factors predicting adolescents'relative psychological adjustment. However, the behavioral adjustment was not predicted by environmental contexts. 5. The resources from school, consumer, and eating behaviors were significant factors predicting adolescents'relative psychological adjustment. Also, the resources from school, eating behavior, and family were predictors of behavioral adjustment. This research implies that the findings can be based on the development of prevention program for adolescents deviant behaviors in low-income families.

• 가정과삶의질연구
• /
• 제4권2호
• /
• pp.53-66
• /
• 1986

The prensent study was aimed to explore the reality of the low-income consumers problem by the comparison among five income classes. Specifically, this study was intended to (1) compare the levels of consumer skill, market risk, and consumer problem among the five income classes, (2) examine the relationship between consumer problem and consumer skill, and the relationship between consumer problem and market risk, and (3) search the types of consumer problems that each income class consumers might experience the most often. For this purpose, a survey was conducted using questionaire on 525 home managers in Seoul. The deta were analyzed by ANOVA and DMR test. The major findings were as follows; First, the consumer skill was the poorest in the low-income consumers. There was curvilinear relationship between consumer skill and income level. Second, the market risk was the highest in the low-income consumers. Market risk had a negative linear relationship with income level. Third, consumer problem was the most serious in the low-income consumers and was the least serious in the middle-income consumers. Fourth, the lower consumer skill and the higher market risk the consumers had, the more consumer problems they tended to experience. Finally, the low-income consumers had relatively more difficulties in door-to-door sale and inferior goods problem than the middle and the high-income consumers. On the other hand, the latter experienced relatively more difficulties in false and misleading advertising, overcharge, unfair bargain, and warrenty-repair-exchange problem than the former. Taken together, the research hypotheses were well supported in this study. It was suggested that the quality and the quantity of the low-income consumers problem were different from those of the middle-and the high-income consumers problem.

• Journal of Korean Neurosurgical Society
• /
• 제46권5호
• /
• pp.451-458
• /
• 2009

Objective : The purpose of this study was to analyze risk factors that are associated with intracranial lesion, and to propose criteria for classification of mild head injury (MHI), and appropriate treatment guidelines. Methods : The study was based on 898 patients who were admitted to our hospital with Glasgow Coma Scale (GCS) score of 13 to 15 between 2003 and 2007. The patients' initial computerized tomography (CT) findings were reviewed and clinical findings that were associated with intracranial lesions were analyzed. Results : GCS score, loss of consciousness (LOC), age and skull fracture were identified as independent risk factors for intracranial lesions. Based on the data ana lysed in this study, MHI patients were divided into four subgroups : very low risk MHI patients are those with a GCS score of 15 and without a history of LOC or headache; low risk MHI patients have a GCS score of 15 and with LOC and/or headache; medium risk MHI patients are those with a GCS score of 15 and with a skull fracture, neurological deficits or with one or more of the risk factors; high risk MHI patients are those with a GCS score of 15 with abnormal CT findings and GCS score of 14 and 13. Conclusion : A more detailed classification of MHI based on brain CT scan findings and clinical risk factors can potentially improve patient diagnosis. In light of our findings, high risk MHI patients should be admitted and treated in same manner as those with moderate head injury.

• 셀메드
• /
• 제4권3호
• /
• pp.21.1-21.5
• /
• 2014

The purpose of this study is to determine the type-2 diabetes risk status of the individuals applying to the internal diseases outpatient clinic and the affecting factors. This descriptive study was conducted on 500 individuals who applied to the internal diseases department of a hospital in Ordu Turkey, between May and June 2010 without diabetes diagnosis. The questionnaire form and Type 2 Diabetes Risk Assessment Form are used to collect the data. For the evaluation of data; independent samples t-test and One-Way Anova are used to evaluate the data. It is determined that the type-2 diabetes risk an score of the individuals participating in the study is $10.4{\pm}5.5$ and 32.4% of them have low type-2 diabetes risk score, 26.6% have slightly elevated score, 18% have moderate score, 16.6% have high and 6.4% have very high type-2 diabetes risk score. It is found that the type-2 diabetes risk mean score of the women participating in the study who are adults, are married, have low education level, are unemployed, are non-smoker, do not drink alcohol and do not have any information about type-2 diabetes is statistically significantly high (p < 0.05). It is determined that 16.6% of the individuals participating in the study have high type-2 diabetes risk and 6.4% have very high type-2 diabetes risk.

• Nuclear Engineering and Technology
• /
• 제44권5호
• /
• pp.459-470
• /
• 2012

From the PSA point of view, the Fukushima accident of Japan in 2011 reveals some issues to be re-considered and/or improved in the PSA such as the limited scope of the PSA, site risk, etc. KAERI (Korea Atomic Energy Research Institute) has performed researches on the development of an integrated risk assessment framework related to some issues arisen after the Fukushima accident. This framework can cover the internal PSA model and external PSA models (fire, flooding, and seismic PSA models) in the full power and the low power-shutdown modes. This framework also integrates level 1, 2 and 3 PSA to quantify the risk of nuclear facilities more efficiently and consistently. We expect that this framework will be helpful to resolve the issue regarding the limited scope of PSA and to reduce some inconsistencies that might exist between (1) the internal and external PSA, and (2) full power mode PSA and low power-shutdown PSA models. In addition, KAERI is starting researches related to the extreme external events, the risk assessment of spent fuel pool, and the site risk. These emerging issues will be incorporated into the integrated risk assessment framework. In this paper the integrated risk assessment framework and the research activities on the emerging issues are outlined.

• 식품보건융합연구
• /
• 제8권1호
• /
• pp.1-7
• /
• 2022

This study classified subjects aged 30 to 64 into normal group, impaired fasting glucose group, and diabetes mellitus patient group based on data from the 6th period of the National Health and Nutrition Examination Survey (2013-2015). Skipping breakfast, lack of physical activity, inadequate sleep time, inadequate weight, excessive drinking, and current smoking are classified as a low health risk group when three or less items are present, and a high health risk group when three or more items are included. By classification, each item included in the physical measurement and biochemical analysis factors and health risk behavior factors was comparatively analyzed. As a result, in the normal group, impaired fasting glucose group, and diabetes group, the average age was higher in the group with high health risk factors than the group with low risk factors, and the male ratio was higher. Body mass index, waist circumference, blood pressure, triglyceride showed a significantly higher result. In the normal group, the fasting blood glucose level and total cholesterol level were also higher in group 2. Therefore, it is thought that it is necessary to control health risk behaviors through lifestyle changes in the normal group, fasting glucose disorder group, and diabetes group.

• 근관절건강학회지
• /
• 제24권2호
• /
• pp.67-76
• /
• 2017

Purpose: The purpose of this study was to evaluate preoperative nutritional status in elderly patients with orthopedic surgery and identify related factors for malnutrition risk. Methods: This study enrolled 337 patient's medical record who underwent orthopedic surgery in hospital between January and December 2015. Data was collected retrospectively. Nutritional status was evaluated by using the Nutritional Risk Screening 2002. Multivariable logistic regression analysis was used to identify independent related factors for malnutrition risk. Results: Malnutrition risk developed in 58 patients (17.2%). Logistic regression analysis identified low physical activity, visual impairment, depression, sleep disorder, low serum calcium level, and low serum albumin level as related factors. Conclusion: Orthopedic surgery in elderly patients was associated with high risk of preoperative malnutrition. The results of this study suggest that evaluating the nutritional status and related factors should be done with preoperative status of elderly patients. At the same time, interventions for nutritional care should be adjusted to meet the nutritional needs of individuals and decrease the risk of malnutrition.