• Title/Summary/Keyword: Low effective index

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Studying the Genetic Diversity and Phenetic Relationships of Porphyra yezoensis Populations in Korea Using Random Amplified Polymorphic DNA (RAPD) (RAPD를 이용한 한국 김 집단의 유전적 다양성과 표현형 관계)

  • Kim, Young-Mog;Eom, Sung-Hwan;Huh, Man Kyu
    • Journal of Life Science
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    • v.29 no.2
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    • pp.152-157
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    • 2019
  • Porphyra yezoensis is a red algal species in the genus Porphyra. The phenetics and genetic diversity of four populations of P. yezoensis in Korea were reconstructed using random amplified polymorphic DNA (RAPD) markers. Overall, 55 fragments were generated among the tested P. yezoensis array with 20 OPERON primers. A total of 30(54.5%) of these bands were polymorphic. The OPA-18-02 band was amplified in the samples of Nakdong population and absent in them of other three populations. The OPA-20-02 band was only amplified in the Seocheon population. Both bands exhibited distinctive patterns in specific populations. The effective number of alleles per locus (Ae) ranged from 1.161 to 1.293 with a mean of 1.366. The Seocheon population had a high expected diversity (0.163). The Nakdong population was an isolated endemic and intertidal zone. Thus the narrow distributed Nakdong population had a low expected diversity (0.092). Shannon's index of phenotypic diversity (I) of the Seocheon population (0.238) was the highest among all populations. Total genetic diversity ($H_T$) varied between 0.132 for OPA-02 and 0.420 for OPA-19. The interlocus variation of genetic diversity ($H_S$) was 0.059 for OPA-18 and 0.339 for OPA-19. On a per locus basis, the proportion of total genetic variation due to differences among populations ($G_{ST}$) ranged from 0.012 for OPA-11 to 0.762 for OPA-18 with a mean of 0.415, indicating that 42% of the total variation was found among these populations. In an assessment of the proportion of diversity present within this species, 58.5% (100%-41.5%) of genetic variation resided within the populations studied. The Nm was estimated to be low (0.705).

The Efficacy of Low Frequency Electroacupuncture Therapy for Weight Loss in Obese Korean Women (저주파 전침 위주의 한방비만치료의 체중감량 효과 및 관련 인자에 관한 연구)

  • Hwang, Deok-Sang;Lee, Yoon-Jae;Lee, Chang-Hoon;Kim, Yong-Suk;Jang, Jun-Bock;Lee, Kyung-Sub
    • The Journal of Korean Obstetrics and Gynecology
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    • v.22 no.2
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    • pp.140-150
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    • 2009
  • Purpose: We investigated the efficacy of electroacupuncture therapy in obese Korean women in order to make basic guidelines for the use of oriental medicine in treating obesity. Methods: Forty women were divided into two groups and each was treated 12 times: 1) one group was treated using electroacupuncture (EA) involving auricular acupuncture and physical treatment, without exercise (EA group, n=10), and 2) the other group was treated using electroacupuncture and exercise (EA plus exercise group, n=30). The EA was applied to subcutaneous fat tissue manually. Body weight was evaluated every visit and body composition was checked at the $1^{st}$ and $12^{th}$ visits. Statistical comparisons were made using SPSS13.0. We compared the weight loss, body mass index (BMI), and body composition before and after treatment using the pairedt-test. The correlations between weight loss and BMI and age were examined. Results: After the $12^{th}$ treatment, both groups showed significant reductions in body weight, BMI, body fat, and body fat percentage. The weight loss averaged 4.58${\pm}$3.87% in the EA group and 4.69${\pm}$3.10% in the EA plus Exercise group. The reduction in skeletal muscle was significant in the EA group, but not significant in the EA plus Exercise group. The speed of the weight loss was correlated with age using Pearson's correlation coefficient. Based on BMI, normal and obese subjects in the EA plus Exercise group had significant reductions in body weight, BMI, body fat, and body fat percentage; the obese subjects also had a significant reduction in skeletal muscle. Conclusion: Combined EA therapy may be effective for weight reduction. Age and BMI were related to weight loss using EA therapy.

Analysis of the relationship between satisfaction and use value of the amount of construction technology information provided (건설기술정보 제공물량의 만족도 및 사용 가치 간의 관계 분석)

  • Seong Yun Jeong;Jin Uk Kim
    • Smart Media Journal
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    • v.12 no.11
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    • pp.154-164
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    • 2023
  • The Construction Technology Information System collects, processes, and provides the public with free of charge 16 types of construction technology-related texts or index information, such as construction standards, construction practices, and construction reports, required at construction sites to enhance domestic construction technology. This study judged that user satisfaction could be increased if the budget was allocated first to the most effective construction technology information DB establishment. For each type of construction technology information, the level of satisfaction felt by the population for the quantity provided and the value of use according to the acquisition and utilization of information were investigated. Reliability between independent variables and dependent variables through a multiple regression analysis process to identify how the demographic characteristics of the population affect user satisfaction and the factors that affect the use value of information for each type of construction technology information. and the correlation was analyzed. The correlation between the demographic characteristics of respondents and users' satisfaction with the provided quantity was generally low, but construction experience, age, etc. were found to have an effect on satisfaction with the provided quantity. In particular, among the demographic measurement items of respondents, the more construction experience they had, the higher their satisfaction level with the quantity provided of low-level technical standards, and it was analyzed that older age had an impact on satisfaction with the quantity provided for small and medium-sized business support information.

Methods for Integration of Documents using Hierarchical Structure based on the Formal Concept Analysis (FCA 기반 계층적 구조를 이용한 문서 통합 기법)

  • Kim, Tae-Hwan;Jeon, Ho-Cheol;Choi, Joong-Min
    • Journal of Intelligence and Information Systems
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    • v.17 no.3
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    • pp.63-77
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    • 2011
  • The World Wide Web is a very large distributed digital information space. From its origins in 1991, the web has grown to encompass diverse information resources as personal home pasges, online digital libraries and virtual museums. Some estimates suggest that the web currently includes over 500 billion pages in the deep web. The ability to search and retrieve information from the web efficiently and effectively is an enabling technology for realizing its full potential. With powerful workstations and parallel processing technology, efficiency is not a bottleneck. In fact, some existing search tools sift through gigabyte.syze precompiled web indexes in a fraction of a second. But retrieval effectiveness is a different matter. Current search tools retrieve too many documents, of which only a small fraction are relevant to the user query. Furthermore, the most relevant documents do not nessarily appear at the top of the query output order. Also, current search tools can not retrieve the documents related with retrieved document from gigantic amount of documents. The most important problem for lots of current searching systems is to increase the quality of search. It means to provide related documents or decrease the number of unrelated documents as low as possible in the results of search. For this problem, CiteSeer proposed the ACI (Autonomous Citation Indexing) of the articles on the World Wide Web. A "citation index" indexes the links between articles that researchers make when they cite other articles. Citation indexes are very useful for a number of purposes, including literature search and analysis of the academic literature. For details of this work, references contained in academic articles are used to give credit to previous work in the literature and provide a link between the "citing" and "cited" articles. A citation index indexes the citations that an article makes, linking the articleswith the cited works. Citation indexes were originally designed mainly for information retrieval. The citation links allow navigating the literature in unique ways. Papers can be located independent of language, and words in thetitle, keywords or document. A citation index allows navigation backward in time (the list of cited articles) and forwardin time (which subsequent articles cite the current article?) But CiteSeer can not indexes the links between articles that researchers doesn't make. Because it indexes the links between articles that only researchers make when they cite other articles. Also, CiteSeer is not easy to scalability. Because CiteSeer can not indexes the links between articles that researchers doesn't make. All these problems make us orient for designing more effective search system. This paper shows a method that extracts subject and predicate per each sentence in documents. A document will be changed into the tabular form that extracted predicate checked value of possible subject and object. We make a hierarchical graph of a document using the table and then integrate graphs of documents. The graph of entire documents calculates the area of document as compared with integrated documents. We mark relation among the documents as compared with the area of documents. Also it proposes a method for structural integration of documents that retrieves documents from the graph. It makes that the user can find information easier. We compared the performance of the proposed approaches with lucene search engine using the formulas for ranking. As a result, the F.measure is about 60% and it is better as about 15%.

THE ANTICANCER EFFECT OF PACLITAXEL($Taxol^{(R)}$) IN ORAL SQUAMOUS CELL CARCINOMA XENOGRAFT (이종 이식된 구강편평세포 암종에서 Paclitaxel ($Taxol^{(R)}$)의 항암 효과)

  • Kim, Ki-Hwan;Kim, Chul-Hwan;Han, Se-Jin;Lee, Jae-Hoon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.2
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    • pp.95-110
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    • 2006
  • The treatment for oral and maxillofacial carcinoma with chemotherapeutic agents is evaluated by many effective methods to reduce the tumor mass and cancer cell proliferation. However these chemotherapy have many serious side effects, such as bone marrow suppression, renal toxicity, G-I troubles. Therefore a possible approach to develop a clinically applicable chemotherapeutic agent is to screen anticancer activity of Taxol which is known to have very little side effect and have been used to breast cancer and ovarian carcinoma. Taxol is a new anti-microtubular anti-cancer agent extracted from the bark of the Pacific yew, Taxus brevifolia. Paclitaxel(Taxol) acts by promoting tubulin polymerization and over stabilizing microtubules agianst depolymerization. Despite the constant improvements of methods of the cancer treatment especially chemotherapy, the rate of cancer metastasis and recurrent are not decreased. Thus the investigation of new drug which have very little side effect and a possible clinically application continues to be a high priority. Considering that the Taxol have shown very effective chemotherapeutic agent with relatively low toxicity in many solid tumors, it deserves to evaluate its efficacy in oral squamous cell carcinoma. In this study, to investigate the in-vivo and in-vitro anti-cancer efficacy of Taxol in oral squamous cell carcinoma and lastly, the potency of Paclitaxel in the clinical application for oral cancer was evaluated. In vivo study, after HN22 cell line were xenografted in nude mice, the growth of tumor mass was observed, 3 mg/Kg taxol was injected intraperitoneally into nude mice containing tumor mass. The methods of these study were measurement of total volume of tumor mass, histopathologic study, immunohistochemical study, drug resistance assay, growth curve, MTT assay, flow cytometry, cDNA microarray in vivo and in vitro. The results were obtained as following. 1. The visual inspection of the experimental group showed that the volume of the tumor mass was slightly decreased but no significant difference with control group. 2. Ki-67 index was decreased at weeks 4 in experimental group. 3. Microscopic view of the xenografted tumor mass showed well differentiated squamous cell carcinoma and after Taxol injection, some necrotic tissue was seen weeks 4. 4. The growth curve of the tumor cells were decreased after 1day Taxol treatment. 5. According to the MTT assay, HN22 cell line showed relative drug resistancy above $5\;{\mu}g/ml$ concentrations of Taxol. 6. In drug resistance assay, the decrease of cell counts was seen relatively according to concentration. 7. In Flow cytometry, G2M phase cell arrests were seen in low concentration of the Taxol, while S phase cell arrests were seen in high concentration of the Taxol. 8. Using cDNA microarray technique, variable gene expression of ANGPTL4, TXNRD1, FAS, RRAGA, CTGF, CYCLINEA, P19, DUSP5, CEBPG, BTG1 were detacted in the oral squamous cell carcinoma cell after taxol treatment. In this study paclitaxel is effective against oral squamous cell carcinoma cell lines in vitro, but week effect was observed in vivo. So we need continuous study about anticancer effect of taxol in vivo in oral squamous cell carcinoma.

Adaptation Strategy in Dry Matter and Seed Production of Rice and Weed Species (벼와 잡초(雜草)의 건물생산(乾物生産) 및 종자생산(鐘子生産) 특성(特性)에 따른 환경적응(環境適應) 전략(戰略))

  • Kim, Soon-Chul;Moody, Keith
    • Korean Journal of Weed Science
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    • v.9 no.3
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    • pp.183-200
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    • 1989
  • An experiment was conducted at the greenhouse of the International Rice Research Institute in 1987 to find out the character of dry matter production, the potential seed production ability and the ecological and physiological strategies to adaptation. For these, two rice cultivars, IR64(lowland rice) and UPLRi-5(upland rice), and seven weed species were used ; Echinochloa glabrescens Munro ex Hook. f., E. cress-galls ssp. hispidula (Retz.) Honda, E. colons (L.) Link, Monochoria vaginalis (Burin. f.), Ludwigia octovalvis Jacq.) Raven, Fimbristylis miliacea Vahl and Cyperus difformis L. Adaptation strategies of weed species varied by species. However, they had efficient seed production strategy through different ways. In general, sedge weed species (F. miliacea and C. difformis) produced great amount of seeds at the expense of seed size through greater ratooning ability and low relative dry weight for flowering. For broadleaved weed species, greater number of descendants were obtained through high plasticity and low relative dry weight for flowering (M. vaginalis) or greater growth ability through effective photosynthetic efficiency (L. octovalvis). Grass weed species, on the other hand, produced their seeds through effective growth (net assimilation rate and relative growth rate), high ratooning ability (except E. crus-galls ssp. hispidula) or low relative dry weight to maximum dry weight for flowering (E. glabrescens). The harvest indices of the weed species were considerably lower than those of rice. Fimbristylis miliacea had the greatest ratooning ability followed by C. difformis, E. colons and E. glabrescens. The greatest seed productivity was recorded by C. difformis (279, 000) and L. octovalvis (268,000) while rice produced the least number of seeds (1300-6100). Log seed weight had a negative linear relationship with log seed number (y=6.30-1.48X, $R=-0.965^{**}$). For all species plant plasticity response was not directly correlated with mortality response.

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STUDIES ON THE EXTRACTION OF SEAWEED PROTEINS 4. Precipitation Conditions and Nutritional Evaluation of Isolated Seaweed proteins (해조단백질 추출에 관한 연구 4. 추출단백질의 심전조건 및 영양적 평가)

  • WOO Soon-Im;RYU Hong-Soo;LEE Kang-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.12 no.4
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    • pp.225-234
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    • 1979
  • For the effective utilization of diverse and abundant resource of seaweeds in Korea as a food protein supplment, extraction conditions of water, salt, and alkali soluble proteins were investigated in previous work(Ryu and Lee, 1977: Lee et al., 1977: Lee et al., 1978). The present study as a part of the serial work was thus aimed to find the conditions of isolation and purification of extracted proteins, and to evaluate the nutritional quality of the isolated seaweed proteins in terms of amino acid composition, chemical score, protein score, modified essential amino acid index(MEAAI), and in vitro digestibility presented as pepsin-pancreatin digest residue index (PPDRI). As for the isolation of extracted proteins, TCA treatment was more effective for the proteins from rhodophyceae and Chlorophyceae while the precipitation at isoelectric point was more desirable for Phaeophyceae proteins. In amino acid composition, water soluble protein fraction was superior to the other fractions in Porphyra suborbiculata whereas both water and alkali soluble fractions seemed to bo more benefitial for Enteromorpha linza and Ulva pertusa; the extraction with alcohol-alkali mixed solvent for Undaria pinnatifida and Sargassum fulvellum. Glutamic acid and aspartic acid content was particularly high in all protein fractions examined. The total amino acid content of Porphyra suborbiculata and Enteromorpha linza was almost equivalent to that of dried whole egg although the essential amino acid content was lower. A comparative analysis was made on the inedexes between raw seaweed powder and isolated protein. Chemical score of Porphyra suborbiculata and Ulva pertusa was approximately 35 and 56 in cafes of raw powder and isolated protein respectively while only 10 to 16 for raw powder of Undaria pinnatifida and Sargassum fulvellum and 30 to 35 for their isolated proteins. Protein score of all isolated proteins was in the range of 63 to 73 which indicates that isolated protein would be mere valuable than the fern of raw seaweed powder. Digestibility by means of PPDRI was found to be extremely low in case of raw powder but it could be doubled in case of isolated protein yielding 67 to 70 for Porphyra suborbiculata and Ulva pertusa.

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Agroclimatic Zone and Characters of the Area Subject to Climatic Disaster in Korea (농업 기후 지대 구분과 기상 재해 특성)

  • 최돈향;윤성호
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.34 no.s02
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    • pp.13-33
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    • 1989
  • Agroclimate should be analyzed and evaluated accurately to make better use of available chimatic resources for the establishment of optimum cropping systems. Introducing of appropriate cultivars and their cultivation techniques into classified agroclimatic zone could contribute to the stability and costs of crop production. To classify the agroclimatic zones, such climatic factors as temperature, precipitation, sunshine, humidity and wind were considered as major influencing factors on the crop growth and yield. For the classification of rice agroclimatic zones, precipitation and drought index during transplanting time, the first occurrence of effective growth temperature (above 15$^{\circ}C$) and its duration, the probability of low temperature occurrence, variation in temperature and sunshine hours, and climatic productivity index were used in the analysis. The agroclimatic zones for rice crop were classified into 19 zones as follows; (1) Taebaek Alpine Zone, (2) Taebaek Semi-Alpine Zone, (3) Sobaek Mountainous Zone, (4) Noryeong Sobaek Mountainous Zone, (5) Yeongnam Inland Mountainous Zone, (6) Northern Central Inland Zone, (7) Central Inland Zone, (8) Western Soebaek Inland Zone, (9) Noryeong Eastern and Western Inland Zone, (10) Honam Inland Zone, (ll) Yeongnam Basin Zone, (12) Yeongnam Inland Zone, (13) Western Central Plain Zone, (14) Southern Charyeong Plain Zone, (15) South Western Coastal Zone, (16) Southern Coastal Zone, (17) Northern Eastern Coastal Zone, (18) Central Eastern Coastal Zone, and (19) South Eastern Coastal Zone. The classification of agroclimatic zones for cropping systems was based on the rice agroclimatic zones considering zonal climatic factors for both summer and winter crops and traditional cropping systems. The agroclimatic zones were identified for cropping systems as follows: (I) Alpine Zone, (II) Mountainous Zone, (III) Central Northern Inland Zone, (IV) Central Northern West Coastal Zone, (V) Cental Southern West Coastal Zone, (VI) Gyeongbuk Inland Zone, (VII) Southern Inland Zone, (VIII) Southern Coastal Zone, and (IX) Eastern Coastal Zone. The agroclimatic zonal characteristics of climatic disasters under rice cultivation were identified: as frequent drought zones of (11) Yeongnam Basin Zone, (17) North Eastern Coastal Zone with the frequency of low temperature occurrence below 13$^{\circ}C$ at root setting stage above 9.1%, and (2) Taebaek Semi-Alpine Zone with cold injury during reproductive stages, as the thphoon and intensive precipitation zones of (10) Hanam Inland Zone, (15) Southern West Coastal Zone, (16) Southern Coastal Zone with more than 4 times of damage in a year and with typhoon path and heavy precipitation intensity concerned. Especially the three east coastal zones, (17), (18), and (19), were subjected to wind and flood damages 2 to 3 times a year as well as subjected to drought and cold temperature injury.

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Early Changes after Death of Plaice, Paralichthys olivaceus Muscle -2. Temperature Dependency on Physicochemical and Rheological Properties- (넙치(Paralichthys olivaceus)육의 사후 조기 변화 -2. 물리 화학적 및 물성적 특성의 온도 의존성-)

  • CHO Young-Je;KIM Yuck-Yong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.26 no.1
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    • pp.1-7
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    • 1993
  • To clarify the effect of storage temperature on the physicochemical and rheological properties of plaice, Paralichthys olivaceus muscle, the changes in IMP accumulation rates, rigor index, breaking strength and K-value of muscle during storage at $0^{\circ},\;5^{\circ}C$ and $10^{\circ}C$ were studied. The maximum speed and content of IMP accumulation were showed in sample stored at $0^{\circ}C$ among the all samples. The content and time reached around the maximum IMP accumulation for each samples were $6.94{\mu}mole/g$ and 30hrs for samples stored at $0^{\circ}C,\;6.30{\mu}mole/g$ and 31.5hrs for $5^{\circ}C$ samples and $5.40{\mu}mole/g$ and 45hrs for $10^{\circ}C$ samples, respectively. Values of breaking strength in sample stored at $5^{\circ}C$ increased rapidly than samples at $0^{\circ}C$ showed maximum values after 10hrs. However, In case of fresh flesh stored at $10^{\circ}C$, there was no increase of breaking strength during storage. The breaking strength was not closely related with rigor index. The times reached around $5\%$ K-value which is representative excellent freshness index of sashimi were 14hrs for samples stored at $0^{\circ}C$, 13hrs for $5^{\circ}C$ samples and 4hrs for $10^{\circ}C$ samples. From the results above, it was suggested that the storage at low temperature($10^{\circ}C{\sim}5^{\circ}C$) was effective in increase the IMP contents and breaking strength, and maintenance the high-freshness of fresh plaice flesh at early periods after death.

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Application of satellite remote sensing-based vegetation index for evaluation of transplanted tree status (이식수목의 현황 평가를 위한 위성영상 기반 원격탐사 식생지수 적용 연구)

  • Mi Na Choi;Do-Hun Lee;Moon-Jeong Jang;Dong Ju Kim;Sun Mi Lee;Yoon Jung Moon;Yong Sung Kwon
    • Korean Journal of Environmental Biology
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    • v.41 no.1
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    • pp.18-30
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    • 2023
  • Forest destruction is an inevitable result of the development processes. According to the environmental impact assessment, over 10% of the destroyed trees need to be recycled and transplanted to minimize the impact of forest destruction. However, the rate of successful transplantation is low, leading to a high rate of tree death. This is attributable to a lack of consideration for environmental factors when choosing a temporary site for transplantation and inadequate management. To monitor transplanted trees, a field survey is essential; however, the spatio-temporal aspect is limited. This study evaluated the applicability of remote sensing for the effective monitoring of transplanted trees. Vegetation indices based on satellite remote sensing were derived to detect time-series changes in the status of the transplanted trees at three temporary transplantation sites. The mortality rate and vitality of transplanted trees before and after the transplant have a similar tendency to the changes in the vegetation indicators. The findings of this study showed that vegetation indices increased after transplantation of trees and decreased as the death rate increased and vitality decreased over time. This study presents a method for assessing newly transplanted trees using satellite images. The approach of utilizing satellite photos and the vegetation index is expected to detect changes in trees that have been transplanted across the country and help to manage tree transplantation for the environmental impact assessment.