• Title/Summary/Keyword: Low effective index

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Anti-pruritic Effect of Botulinum Toxin Type A against Histamine-induced Pruritus on Canine Skin (개에서 Histamine으로 유발한 피부소양증에 대한 보툴리늄 톡신의 항소양 효과)

  • Jeong, Byung-Han;Kim, Tae-Wan;Lee, Keun-Woo;Oh, Tae-Ho
    • Journal of Veterinary Clinics
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    • v.28 no.3
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    • pp.273-279
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    • 2011
  • Botulinum toxin type A (BoNT/A) has been proven to be a safe and effective treatment for wrinkles in human. As well as the anti-wrinkle effects, the anti-pruritic effect of BoNT/A has been revealed from several researches for new therapy. The aim of this study was to investigate the anti-pruritic effect of BoNT/A against histamine-induced pruritus on canine skin. Five clinically healthy beagles were included in the study. All dogs were received 0.05 ml (5 Unit) of BoNT/A on the right dorsal thoracic region as an experiment and the same volume of saline solution was injected on the left dorsal thoracic region as a control, respectively. Intradermal histamine injections were performed four times (before treatment and days 1, 3 and 7 after BoNT/A injection). The severity of pruritus, the diameter and thickness of wheal, the erythema index and cutaneous temperature were assessed. The severity of pruritus was reduced on BoNT/A treated sides, compared with saline treated sides (p < 0.05). BoNT/A decreased wheal size, in both diameter and thickness (p < 0.05). Although, erythema index of both sides were increased after first histamine injection, BoNT/A treated sides showed the low-value as compared with saline treated sides. Cutaneous temperature was decreased significantly on BoNT/A treated sides. These results indicates that BoNT/A reduce histamine-induced pruritus on canine skin and suggested a possibility of application of BoNT/A for local intractable dermatologic problem in dogs.

Investigation on Influencing Environmental Factors on Health Status of Korean Septuagenarians Dwelling in Longevity Region in Jeonla Province (전라도 농촌장수지역 거주 70대 노인의 건강상태에 영향을 미치는 환경적 요인에 대한 탐색 연구)

  • Kwak, Chung Shil;Yon, Miyong;Lee, Mee Sook;Oh, Se In;Park, Sang Chul
    • Korean Journal of Community Nutrition
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    • v.19 no.2
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    • pp.142-162
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    • 2014
  • Objectives: To evaluate the critical environmental factors on healthy-aging of Korean people, we investigated the significant factors influencing health status of septuagenarians living in rural area of Jeonla province, known to be one of the representative longevity regions in Korea. Methods: We divided subjects into healthy group (36M/25F) or poor-health group (26M/73F) based on self-reported health status, body mass index, a number of prescription, and blood test data. General characteristics, physical measurements, lifestyle, dietary behavior and nutrient intake, physical health and mental health data were statistically compared between the two groups. Results: Average age was not different between healthy group and poor-health group in men and women, respectively. In men, significantly favorable factors to health were observed to be higher education, regular exercise, higher grip strength and walking function, body mass index (${\geq}18.5kg/m^2$), moderate frequency of drinking and eating-out, non-smoking, normal red blood cell (RBC) count, higher serum dehydroepiandrosterone-sulfate (DHEAS) level, good digestive function and appetite, normal hearing function, regular meals, adequate vegetable and fruit intake, diverse food intake, adequate energy and nutrients (protein, vitamin $B_1$, $B_6$, C and E, folate, niacin, P, Zn and K) intake, higher mini-nutrient status assessment (MNA) score and low level of depression. On the other hand, in women, those were literacy, living arrangement, moderate frequency of drinking, healthy teeth, higher grip strength and walking function, bone mineral density, normal RBC and white blood cell (WBC) count, higher DHEAS concentration, higher MNA score, normal cognition and memory function, having snack and adequate fruit intake. Conclusions: These results could be useful to plan effective strategies to increase health-life expectancy of Korean old people living in rural areas.

Development of Functional Hanji Added Citrus Peel(I) - Hanji added Korean citrus peel - (감귤박을 첨가한 기능성 한지제조 기술개발(제1보) - 한국산 감귤박 첨가 한지 -)

  • Kim, Hae-Gong;Lim, Hyun-A;Kim, So-Young;Kang, Sool-Saeng;Lee, Hyo-Yeon;Yun, Pil-Yong
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.39 no.1 s.119
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    • pp.38-47
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    • 2007
  • This study was carried out to develop a new application field and obtain the basic data of citrus peel as waste in Jeju island and traditional Hanji for producing functional Hanji. The results measuring physical and optical properties, water vapor permeance and antibacterial activity are as follows. It was revealed that apparent density go as down but bulk raise up in the structural view of Hanji with increasing of the addition various Korean citrus peel (citrus unshiu, cheonggyun and hanrabong peel, and citrus unshiu peel powder) percentages, and that the density of Hanji added citrus unshiu peel was higher, but bulk was lower in compared with Hanji added other kinds of peel. Those Hanji added citrus unshiu peel, cheonggyun peel, hanrabong peel and citrus unshiu powder were very great not only in the strength (breaking length, burst index, tear index and folding endurance) but also in water vapor permeant rate in comparison with Hanji. The pHs of Hanji were neutrality (7 to 8). The brightness of the Hanji added various citrus peel percentages was low in compared to Hanji, and the 40% addition of hanrabong peel was the lowest. When 40% hanrabong peel was added to Hanji, it was very yellow in the color degree. When cheonggyun peel was added to Hanji manufacture, water vapor permeant rate was highly effective. It is known that vacant space of intrafiber was reduced by image analysis of Hanji and the additions of peel of citrus unshiu, cheonggyun and hanrabong were distributed equally in the interior of Hanji. The antibacterial activity of Hanji added citrus unshiu peel is more than 98%. After all, it would be able to increase utilization of Hanji, extensively. Namely, production of high quality Hanji added functional materials is expected for new valuable industry of citrus peel and Hanji.

Factors and Countermeasures for Middle School Students' School Related Stress (중학생의 학교 스트레스 요인과 대처방식)

  • Jang, In-Yeol;Park, Young-Soo
    • The Journal of Korean Society for School & Community Health Education
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    • v.4
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    • pp.61-78
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    • 2003
  • This research was conducted to identify the factors that cause school related stress among middle school students, and to develop countermeasures in order to prevent the rebellious acts of middle school students that are on the rise and to pursue after effective guidance measures. To achieve these research objectives, 856 questionnaires were distributed to the two middle schools, situated in Goyang-si, Gyeonggi Province, and these questionnaires were analyzed, using the SPSS statistical package program. The conclusions were as follows; 1. Perceived factors for School Related Stress Overall average of the perceived degree school related stress factors was a level that goes beyond the normalcy. Stress on the grade was the highest Among these, the average of question items that addressed decrease in grade was the highest of all items followed by class factors, teacher-related factors, friend-related factors, and environmental factors. Accordingly, this research demonstrated that the students feel pressured by the university entrace examination and a school life that is focused on grades. The teacher-related factors and class factors were higher than the average, and others were relatively low. 2. School Related Stress according by Individual All the factors for school related stress were statistically significant difference according to the gender, and teacher-related factors, class factors, and environmental factors were statistically significant difference according to their school years. Their grade made their grade factors statistically significant difference, and the number of friends produced a statistically significant difference result on the teacher-related factors. Wheather they had extra classes or not made a statistically significant difference result on the class factors and environmental factors, and especially the time of doing physical exercises produced statistically significant difference on the environmental factors. 3. Countermeasures for School Related Stress according by Individual As for the countermeasures for school related stress according to the individuality, the active reacting was statistically significant difference according to the gender index, and the student's degree to react passively was statistically significant difference according to their grade. The students in different school years showed statistically significant difference reactions in both passive ways and active ways. students tended to react differently in an unreality index. Lastly, Wheather they had extra classes and physical exercises made then to react passively or actively. When the results are compiled, students are most affected by the stress related to grades, which reflected the university entrance examination oriented school life. An alternative is that the development of educational program that factors in the students' talents and aptitude is needed urgently. Moreover, character and career path related guidance and education are just as important as the academics. Given that the stress factors exert some degree of influence on the countermeasures, it is necessary to block the factors in advance and for all the teachers and parents to make an effort to react actively.

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Adaptation Policy of ISO 27001 ISMS (Information Security Management System) for e-Government (전자정부 정보보호관리체계(G-ISMS) 적용 정책)

  • Han, Keun-Hee
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.19 no.5
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    • pp.119-130
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    • 2009
  • Korea ranked 2nd in the UN Global e-Participation Index and ranked number one as the leader in e-Government for the third consecutive year. However, Korea ranked 51 in the level of information security published by WEF(World Economic Forum), relatively a low level comparing with its great number of users and excellent environments for the Internet service. A series of critical hacking accidents such as the information leak at Auction and GS Caltex emerged consecutively in 2008 year, resulting in the leak of personal & critical information. This led to a strong interest in the necessity and importance of information security and personal information so that demand for IT security is growing fast. In this paper, we survey to benchmark information security in the perspective of service level, system, investment and policy about major foreign countries. Then we research on an effective way to make the most of the benchmark result to Korea e-Government. In addition, the purpose of this paper is to improve national information security index by developing a policy for ISO 27001 ISMS, an international standard for Information Security Management System, and elevate safety and security of the e-Government serviced by central administrative organizations and local authorities.

A Study on the Cloud Detection Technique of Heterogeneous Sensors Using Modified DeepLabV3+ (DeepLabV3+를 이용한 이종 센서의 구름탐지 기법 연구)

  • Kim, Mi-Jeong;Ko, Yun-Ho
    • Korean Journal of Remote Sensing
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    • v.38 no.5_1
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    • pp.511-521
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    • 2022
  • Cloud detection and removal from satellite images is an essential process for topographic observation and analysis. Threshold-based cloud detection techniques show stable performance because they detect using the physical characteristics of clouds, but they have the disadvantage of requiring all channels' images and long computational time. Cloud detection techniques using deep learning, which have been studied recently, show short computational time and excellent performance even using only four or less channel (RGB, NIR) images. In this paper, we confirm the performance dependence of the deep learning network according to the heterogeneous learning dataset with different resolutions. The DeepLabV3+ network was improved so that channel features of cloud detection were extracted and learned with two published heterogeneous datasets and mixed data respectively. As a result of the experiment, clouds' Jaccard index was low in a network that learned with different kind of images from test images. However, clouds' Jaccard index was high in a network learned with mixed data that added some of the same kind of test data. Clouds are not structured in a shape, so reflecting channel features in learning is more effective in cloud detection than spatial features. It is necessary to learn channel features of each satellite sensors for cloud detection. Therefore, cloud detection of heterogeneous sensors with different resolutions is very dependent on the learning dataset.

Analysis of effects of drought on water quality using HSPF and QUAL-MEV (HSPF 및 QUAL-MEV를 이용한 가뭄이 수질에 미치는 영향 분석)

  • Lee, Sangung;Jo, Bugeon;Kim, Young Do;Lee, Joo-Heon
    • Journal of Korea Water Resources Association
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    • v.56 no.6
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    • pp.393-402
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    • 2023
  • Drought, which has been increasing in frequency and magnitude due to recent abnormal weather events, poses severe challenges in various sectors. To address this issue, it is important to develop technologies for drought monitoring, forecasting, and response in order to implement effective measures and safeguard the ecological health of aquatic systems during water scarcity caused by drought. This study aimed to predict water quality fluctuations during drought periods by integrating the watershed model HSPF and the water quality model QUAL-MEV. The researchers examined the SPI and RCP 4.5 scenarios, and analyzed water quality changes based on flow rates by simulating them using the HSPF and QUAL-MEV models. The study found a strong correlation between water flow and water quality during the low flow. However, the relationship between precipitation and water quality was deemed insignificant. Moreover, the flow rate and SPI6 exhibited different trends. It was observed that the relationship with the mid- to long-term drought index was not significant when predicting changes in water quality influenced by drought. Therefore, to accurately assess the impact of drought on water quality, it is necessary to employ a short-term drought index and develop an evaluation method that considers fluctuations in flow.

Utilization of Weather, Satellite and Drone Data to Detect Rice Blast Disease and Track its Propagation (벼 도열병 발생 탐지 및 확산 모니터링을 위한 기상자료, 위성영상, 드론영상의 공동 활용)

  • Jae-Hyun Ryu;Hoyong Ahn;Kyung-Do Lee
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.25 no.4
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    • pp.245-257
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    • 2023
  • The representative crop in the Republic of Korea, rice, is cultivated over extensive areas every year, which resulting in reduced resistance to pests and diseases. One of the major rice diseases, rice blast disease, can lead to a significant decrease in yields when it occurs on a large scale, necessitating early detection and effective control of rice blast disease. Drone-based crop monitoring techniques are valuable for detecting abnormal growth, but frequent image capture for potential rice blast disease occurrences can consume significant labor and resources. The purpose of this study is to early detect rice blast disease using remote sensing data, such as drone and satellite images, along with weather data. Satellite images was helpful in identifying rice cultivation fields. Effective detection of paddy fields was achieved by utilizing vegetation and water indices. Subsequently, air temperature, relative humidity, and number of rainy days were used to calculate the risk of rice blast disease occurrence. An increase in the risk of disease occurrence implies a higher likelihood of disease development, and drone measurements perform at this time. Spectral reflectance changes in the red and near-infrared wavelength regions were observed at the locations where rice blast disease occurred. Clusters with low vegetation index values were observed at locations where rice blast disease occurred, and the time series data for drone images allowed for tracking the spread of the disease from these points. Finally, drone images captured before harvesting was used to generate spatial information on the incidence of rice blast disease in each field.

The Effect of Red-Yeast-Rice Supplement on Serum Lipid Profile and Glucose Control in Subjects with Impaired Fasting Glucose or Impaired Glucose Tolerance (공복 혈당장애 및 내당능장애자에서 홍국의 섭취가 혈중지질 및 혈당 조절에 미치는 영향)

  • Kang, Mi-Ran;Kim, Ji-Young;Hyun, Yae-Jung;Kim, Hyae-Jin;Yeo, Hyun-Yang;Song, Young-Duk;Lee, Jong-Ho
    • Journal of Nutrition and Health
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    • v.41 no.1
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    • pp.31-40
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    • 2008
  • This study was aimed at evaluating the effect of red-yeast-rice supplementation on cholesterol-lowering and glucose control in subjects with impaired fasting glucose (IFT) or impaired glucose tolerance (IGT). We conducted a doubleblind, placebo-controlled study with 3 groups; placebo, low dose group (red yeast rice 210.0mg/capsule, 2.52g/day) and high dose group (red yeast rice 420.0mg/capsule, 5.04g/day), which were randomly assigned to subjects with impaired fasting glucose or impaired glucose tolerance. We measured fasting serum concentrations of total-, LDL-, HDL-cholesterol, triglyceride, glucose, insulin, free fatty acid (FFA) and 2 h oral glucose tolerence test (OGTT) before and after the supplementation. Both low dose and high dose groups had significant decrease in LDL cholesterol and atherogenic index (AI) compared with placebo group (p<0.05). Additionally, total and HDL cholesterol improved significantly in high dose group compared with placebo group (p<0.05). Fasting serum glucose decreased in test groups and increased in placebo group after intervention. However, it was not significant differences. In subjects which fasting blood glucose is more than 110mg/dL, fasting glucose had a tendency to decrease in high dose group (p<0.1) and Hemoglobin A1c (HbA1c) had significant decrease in low dose group (p<0.05), while insulin and HOMA-IR had a tendency to increase in placebo group after intervention. Mean changes of glucose related parameters (fasting glucose, insulin, HOMA-IR) compared with placebo group did not show significant differences. In conclusion, subjects with impaired fasting glucose or impaired glucose tolerance were significantly improved in serum lipid profile by red yeast rice supplementation without serious side effects. These are more effective in the case of a high dose. The effects of red yeast rice supplementation on glucose control were insignificant.

Correlation between Carotid Intima-media Thickness and Risk Factors for Atherosclerosis (경동맥 내중막 두께에 따른 죽상경화반의 위험요인과의 상관관계)

  • An, Hyun;Lee, Hyo Yeong
    • Journal of the Korean Society of Radiology
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    • v.13 no.3
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    • pp.339-348
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    • 2019
  • The purpose of this study was to investigate the effect of carotid artery ultrasound Respectively. The carotid intima-media thickness is known to have a significant correlation with cardiovascular disease and cerebrovascular disease. We investigated the relationship between carotid intima - media thickness, body mass index, waist circumference, the blood lipid value, fasting blood glucose, glycated hemoglobin, and blood pressure using carotid artery ultrasound. The carotid artery ultrasound was considered to be abnormality of IMT thickness over 0.8 mm and the presence or absence of atherosclerotic plaque was evaluated. Serological tests were used to compare the geologic value, fasting blood glucose level, and glycated hemoglobin. As a result, waist circumference (=.022), low density cholesterol (=.004), fasting blood glucose level (.019), and glycemic index (.002) were analyzed as predictors of atherosclerosis. In the ROC curve analysis, sensitivity was 87.80% (95% CI: 73.8-95.9), specificity was 41.67% (95% CI: 30.2-53.9), sensitivity was 78.05% (95% CI: 62.4-89.4) in low density lipoprotein, Specificity was 50.00% (95% CI: 38.0-62.0), sensitivity was 73.11% (95% CI: 57.1-85.8), specificity was 61.11 (95% CI: 48.9-72.4) and sensitivity was 82.93%-91.8) and a specificity of 43.06% (31.4-55.3). In logistic regression analysis, the risk of atherosclerosis was 0.248 times at waist circumference (WC)> 76 cm, 3.475 times at low-density lipoprotein (LDL-C) ${\geq}124mg/dL$, 0.618 at HbA1c> 5.4% It appeared as a times. We suggest that prospective study of carotid artery ultrasound should be performed for the effective prevention of cardiovascular diseases.