Browse > Article
http://dx.doi.org/10.7742/jksr.2019.13.3.339

Correlation between Carotid Intima-media Thickness and Risk Factors for Atherosclerosis  

An, Hyun (Department of Radiology, Inje University Busan Paik Hospital)
Lee, Hyo Yeong (Department of Radiological Science, Dongeui University)
Publication Information
Journal of the Korean Society of Radiology / v.13, no.3, 2019 , pp. 339-348 More about this Journal
Abstract
The purpose of this study was to investigate the effect of carotid artery ultrasound Respectively. The carotid intima-media thickness is known to have a significant correlation with cardiovascular disease and cerebrovascular disease. We investigated the relationship between carotid intima - media thickness, body mass index, waist circumference, the blood lipid value, fasting blood glucose, glycated hemoglobin, and blood pressure using carotid artery ultrasound. The carotid artery ultrasound was considered to be abnormality of IMT thickness over 0.8 mm and the presence or absence of atherosclerotic plaque was evaluated. Serological tests were used to compare the geologic value, fasting blood glucose level, and glycated hemoglobin. As a result, waist circumference (=.022), low density cholesterol (=.004), fasting blood glucose level (.019), and glycemic index (.002) were analyzed as predictors of atherosclerosis. In the ROC curve analysis, sensitivity was 87.80% (95% CI: 73.8-95.9), specificity was 41.67% (95% CI: 30.2-53.9), sensitivity was 78.05% (95% CI: 62.4-89.4) in low density lipoprotein, Specificity was 50.00% (95% CI: 38.0-62.0), sensitivity was 73.11% (95% CI: 57.1-85.8), specificity was 61.11 (95% CI: 48.9-72.4) and sensitivity was 82.93%-91.8) and a specificity of 43.06% (31.4-55.3). In logistic regression analysis, the risk of atherosclerosis was 0.248 times at waist circumference (WC)> 76 cm, 3.475 times at low-density lipoprotein (LDL-C) ${\geq}124mg/dL$, 0.618 at HbA1c> 5.4% It appeared as a times. We suggest that prospective study of carotid artery ultrasound should be performed for the effective prevention of cardiovascular diseases.
Keywords
Intima media thickness; Plaque; Hematological test; atherosclerosis;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Y. H. Lee, L. H. Cui, M. H Shin, S. S. Kweon, K. S. Park, S. K Jeong, E. K. Chung, J. S. Choi, "Associations between Carotid Intima-media Thickness Plaque and Cardiovascular Risk Factors J Prev Med Public Health, Vol. 39, No. 6, pp. 477-484, 2006.
2 Korean Statistical Information Service [Internet]. Available from: http://www.kosis.kr/
3 J. T. Salonen, R. Salonen, "Ultrasound B-mode imaging in observational studies of atherosclerotic progression," Circulation: Journal of the American Heart Association, Vol. 87, No. 3(Suppy l), pp. 1156-1165, 1993.
4 J. F. Polak, D. H. O'Leary, R. A. Kronmal, S. K. Wolfson, M. G. Bond, R. P. Tracy, J. M. Gardin, S. J. Kittner, T. R. Price, P. J. Savage, "Sonographic evaluation of carotid artery atherosclerosis in the elderly: relationship of disease severity to stroke and transient ischemic attack," Radiology, Vol. 188, No. 2, pp. 363-370, 1993.   DOI
5 R. Kawamoto, M. Abe, "Risk factors related to the wall thickness of the common carotid artery in elderly patients," Nihon Ronen Igakkai Zasshi, Vol. 33, No. 11, pp. 835-839, 1996.   DOI
6 K. S. Kim, "Do we need individual measurement of carotid intima and media thickness?," The Korean Association of Internal Medicine, Vol. 75, No. 2, pp. 176-178, 2008.
7 S. Ebrahim, O. Papacosta, P. Whincup, et al. "Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women", Stoke, Vol. 30, No. 4, pp. 841-50, 1999.
8 D. H. O'Leary, J. F. Polak, R. A. Kronmal, T. A. Manolio, G. L. Burke, S. K. Wolfson Jr, "Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults", the New England Journal of Medicine, Vol. 340, No. 1, pp. 14-22, 1999.   DOI
9 D. K. Cho, S. U. Kwon, S. W. Kim, J. I. Park, S. H. Lim, S. J. Lim, Y. J. Choi, J. D. Sung, S. H. Lee, K. P. Hong, J. E. Park, D. I. Kim, Y. W. Kim, Y. H. Choi, "Risk Factors and Predictors for the Progression of Carotid Atherosclerotic Stenosis in Korean Adults," The Korean Society of Circulation, Vol. 35, No. 11, pp. 834-840, 2005.   DOI
10 S. M. Grundy, J. I. Cleeman, S. R. Daniels, K. A. Donato, R. H. Eckel, B. A. Franklin, D. J. Gordon, R. M. Krauss, P. J. Savage, S. C. Smith, J. A. Spertus, F. Costa, "Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement," Circulation: Journal of the American Heart Association, Vol. 112, No. 17, pp. 2735-2752, 2005.   DOI
11 O. Onbas, M. Kantarci, A. Okur, U. Bayraktutan, Edis A, Ceviz N. Carotid intima-mediathickness: is it correlated with stroke side? Acta Neurol Scand Vol. 111, No. 3, pp. 169-171, 2005.   DOI
12 A. Kitamura, H. Iso, Imano H, T. Ohira, T. Okada, Sato S, et al. "Carotid intima-media thickness and plaque characteristics as a risk factor for stroke in Japanese elderly men," Stroke, Vol. 35, No. 12, pp. 2788-2794, 2004.   DOI
13 C. S. Kim, H. J. Kim, Y. J. Won, D. J. Kim, E. S. Kang, C. W. Ahn, B. S. Cha, S. K. Lim, K. R. Kim, H. C. Lee, K. B. Huh, "Normative values of carotid artery intima-media thickness in healthy Korean adults and estimation of macrovascular diseases relative risk using this data in type 2 diabetes patients," Diabetes Research and Clinical Practice, Vol. 72, No. 2, pp. 183-189, 2006.   DOI
14 Y. H. Choi, "Principles of Carotid Sonography and Sonographic Anatomy," Korean Journal of Stroke, Vol. 3, No. 1, pp. 31-39, 2001.
15 R. Salonen, J. T. Salonen, "Progression of carotid atherosclerosis and its determinants: A population-based ultrasonography study", Atherosclerosis Vol. 81, No. 1, pp. 33-40, 1990.   DOI
16 Y. Sun, C. H. Lin, C. J. Lu, P. K. Yip, R. C. Chen, "Carotid atherosclerosis, intima media thickness and risk factors-an analysis of 1781 asymptomatic subjects in Taiwan", Atherosclerosis, Vol. 164, No. 1, pp. 89-94, 2002   DOI
17 Y. L. Cho, D. J. Kim, H. D. Kim, S. H. Choi, S. K. Kim, H. J. Kim, C. W. Ahn, B. S. Cha, S. K. Lim, K. R. Kim, H. C. Lee, K. B. Huh, "Reference values of carotid artery intima-media thickness and association with atherosclerotic risk factors in healthy subjects in Korea," The Korean Association of Internal Medicine, Vol. 64, No. 3, pp. 275-293, 2003.
18 T. Mannami, M. Konishi, S. Baba, N. Nishi, A. Terao, "Prevalence of asymptomatic carotid atherosclerotic lesions detected by high-resolution ultrasonography and its relation to cardiovascular risk factors in the general population of a Japanese city", Stroke, Vol. 28, No. 3, pp. 518-525, 1997.   DOI