• Clinical and Molecular Hepatology
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• v.24 no.4
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• pp.392-401
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• 2018

Background/Aims: Leptin is associated with metabolic disorders, which predispose one to non-alcoholic fatty liver disease (NAFLD). The role of leptin in NAFLD pathogenesis is not fully understood. We aim to investigate the association between serum leptin level and severity of NAFLD using U.S. nationally representative data. Methods: Data were obtained from the United States Third National Health and Nutrition Examination Survey. NAFLD was defined by ultrasound detection and severity of hepatic steatosis in the absence of other liver diseases. The severity of hepatic fibrosis was determined by NAFLD fibrosis score (NFS). We used multivariate survey-weighted generalized logistic regression to evaluate the association between leptin level and the degree of NAFLD. We also performed subgroup analyses by body mass index (lean vs. classic NAFLD). Results: Among 4,571 people, 1,610 (35%) had NAFLD. By ultrasound findings, there were 621 people with mild, 664 with moderate, and 325 with severe steatosis. There were 885 people with low NFS (<-1.455, no significant fibrosis), 596 with intermediate NFS, and 129 with high NFS (>0.676, advanced fibrosis). Leptin levels for normal, mild, moderate and severe steatosis were $10.7{\pm}0.3ng/mL$, $12.1{\pm}0.7ng/mL$, $15.6{\pm}0.8ng/mL$, $16{\pm}1.0ng/mL$, respectively (trend P-value<0.001). Leptin levels for low, intermediate, and high NFS were $11.8{\pm}0.5ng/mL$, $15.6{\pm}0.8ng/mL$, $28.5{\pm}3.5ng/mL$, respectively (trend P-value<0.001). This association remained significant even after adjusting for known demographic and metabolic risk factors. In the subgroup analysis, this association was only prominent in classic NAFLD, but not in lean NAFLD. Conclusions: Serum leptin level is associated with the severity of NAFLD, especially in classic NAFLD patients.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.9 no.3
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• pp.181-189
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• 2011

The smooth construction and operation of nuclear facilities requires understanding and support of both the local residents and the national people. It is essential that our country, which should maintain using nuclear energy for national energy security and economic growth, shall improve the social acceptance of nuclear energy. In order to identify the level of social acceptance of nuclear energy, this study investigated the perception of the local residents in Gyeongju and the public in other areas on a nuclear power plant and a low- and intermediate-level radioactive waste disposal facility through an individual interview. The subjects of the investigation were 450 persons. This study identified that perceptions of the respondents were somewhat dependent on the residential area, and derived the implications to be reflected in establishing the customized public-relation strategies.

• Journal of the Korean Society of School Health
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• v.6 no.1
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• pp.58-68
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• 1993

This study was designed to grasp the knowledge and practice the level about visual impairment protective care of the primary school students and also analyse the state of visual impairment. The subjects of this study ware 347 students composed of 456 boys and 391 girls in primary school students. The data were collected by questionaire developed for the purpose of this study which has been made through studying references. These were carried out from the 10th to 30th of June 1992. Analysis of the data was done utilizing SPSS for percentage, mean, S.D., T-test., ANOVA and Pearson's Correlation Coefficient. The major results obtained from this study were as follows: 1. The level of the knowledge about visual impairment protective care was in intermediate range (mean on 20 point scale of 12.34, with O=definitely no), but low in aspects of preventive care for overwork of eye (mean on 5 point scale of 2.67). 2. The level of the practice about visual impairment protective care was intermediate range (mean on 20 point scale of 12.34, with O=definitely no), but low in aspects of preventive care for overwork of eye (mean on 5 point scale of 2.58). 3. Significant variables influencing knowledge of visual impairment protective care were sex (p<0.01) and grade (p<0.001). 4. Significant variables influencing practice of visual impairment protective care was living area (p<0.01). 5. Correlation between knowledge and practice: Those who have more knowledge score have more practice score (p<0.001). 6. vision impairment state 1) Student with subnormal in 0.9 or less were 26.3% in left eye and 28.4% in right eye. 2) Student with subnormal in 0.6 or less were 11.9% in left eye and 10.9% in right eye. 7. Vision impairment programs 1) Males are slightly higher in the degree of visual impairment than females. 2) Visual impairment were increased in accordance with the increase of grade. 3) Urban students are higher in the degree of visual impairment than rural students, but these seem to have no statistical meaning.

• Nuclear Engineering and Technology
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• v.35 no.5
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• pp.482-496
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• 2003

effectiveness of the PAM graphite-electrode technology for the treatment of many types of low-level radioactive waste including : combustible material, solidified resins in cement, inorganic materials, steel, glass, and solidified boric acid cement. The objectives of PAM-200 evaluation were to verify that 1) the facility meets air emission regulations, 2) the facility can be safely operated when processing hazardous and radioactive materials and 3) satisfactory final waste forms can be produced. Results, derived from KAERI's(Korea Atomic Energy Research Institute) analyses for samples of vitrified product, scrubbing solution and offgas collected during test period, show that PAM-200 can treat radioactive wastes as well as hazardous wastes with toxic constituents and radionuclides contained in the offgas exiting from the stack to the environment controlled to be far lower than the limit regulated by air conservation law and atomic law.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.06a
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• pp.205-210
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• 2005

The proposed regulation for low and intermediate level radioactive waste disposal facility, scheduled to be revised, recommends that the waste generator should verify the radioactive waste conforms to the disposal requirements before disposing of it. According to the regulation, the radionuclide concentration of the radioactive waste, and its physical and chemical characteristics and safety must be confirmed prior to the disposal of low and intermediate level radioactive wastes, and the waste generator is required to deliver this information to the disposal facility operator. In addition, the disposal facility operator must assess the safety of the disposal site to establish the SWAC (Site Specific Waste Acceptance Criteria) in consideration of the characteristics of the site, whereas the waste generator must comply with the criteria in managing, disposing of and delivering low and intermediate level radioactive wastes. To abide by the afore-mentioned regulation and criteria, the waste generator must verify that the radioactive wastes to be disposed of are suitable for disposal before they are transported to the disposal facility, and to this end a radioactive waste certification program must be developed. This study conducted an in-depth analysis of the radioactive waste certification programs enforced in countries advanced in atomic energy to develop a draft of a certification program applicable to local power plants, and the program is currently applied as pilot to Uljin Power Plants No. 1 & 2 to prove its applicability. This study is going to analyze the results of the pilot application with a view to developing a radioactive waste certification program suitable to local conditions.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2003.11a
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• pp.524-531
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• 2003

The usefulness of vitrification technology for low- and intermediate- level radioactive wastes was demonstrated because of high volume reduction, mechanical and chemical stability of final waste forms. Thus, a construction of the commercial vitrification plant Is currently promoted. Due to the high radiation level of the waste, shielding analysis has to be carried out for safe design in a vitrification facility. Because there has been no experience in the construction and operation of the vitrification facility in Korea, in this study, in order to get some information for help the detailed design and plan for operation in vitrification facility, shielding analysis for each facility in pilot plant is carried out by using source term from established study. For the selection of the shielding material, concrete was chosen compared to the lead because of economic advantage, weight consideration, and thermal resistance.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.06a
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• pp.211-220
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• 2005

The concrete structure is being considered for the main engineered barrier of low and intermediate level radwaste disposal facility. Concrete of low permeability can minimize infiltration of water and effectively prevent release of nuclide to ecosystem. But if concrete degrades, structural stability of disposal structure will decrease while permeability increase, resulting in increased possibility of nuclide release due to water infiltration. Therefore disposal concrete structure degradation shall be minimized to maintain capacity of nuclide isolation. The typical causes of concrete structure degradation are sulfide attack, reinforcement corrosion due to chloride attack, leaching of calcium hydroxide, alkali-aggregate reaction and repeated freezing-thawing. The common cause of these degradation processes is infiltration of water or adverse chemicals into concrete. Based on the study of these degradation characteristics and mechanisms of concrete structure, the methodology of design and service life evaluation of concrete structure as an engineered barrier are reviewed to ensure its long-term durability.

• The Journal of Engineering Geology
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• v.11 no.3
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• pp.245-254
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• 2001

The experimental study on disposal cover through the performance test facility offers reliability in the safety of near surface disposal of low and intermediate level radioactive waste. To ensure the long-term safety of the repository, the impermeability, integrity, resistance to degradation and ease of maintenance might be considered as the basic performance requirement of the disposal cover. considering the difficulties to meet these performance requirement by using single layer, the disposal cover design which is composed of top layer, middle drainage layer and bottom low permeability layer is schemed for the test facility. The water balance of the cover was evaluated by using HELP code. For the long-term monitoring of the soil moisture content and matric potential, TDR probes and tensiometers will be installed in 6 test cells. Each test cell is dimensioned 3$\times$3$\times$3.3m.

• Economic and Environmental Geology
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• v.51 no.2
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• pp.131-147
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• 2018

In the present study, the safety of the near surface disposal facility for low- and intermediate-level radioactive waste (LILW) is examined based on the fluid-flow simulation model. The effects of the structural design and hydrological properties of the disposal system are quantitatively evaluated by estimating the flux of infiltrated water at the boundary of the structure. Additionally, the safety margins of the disposal system, especially for the cover layer and vault, are determined by applying the various scenarios with consideration of possible facility designs and precipitation conditions. The overall results suggest that the disposal system used in this study is sufficiently suitable for the safe operation of the facility. In addition, it is confirmed that the soundness of both the cover layer and the vault have great impact on the safety of the facility. Especially, as shown in the vault degradation scenario, capability of the concrete barrier of the vault make more positive contribution on the safe operation of the facility compared to that of the cover layer.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.4 no.2
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• pp.187-195
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• 2006

The regulation for the low and intermediate level radioactive waste to be transferred to the disposal facility, recently revised, require that radioactive waste generators should set up waste certification program to verify the radioactive waste conform to the waste acceptance criteria(WAC) before disposal. The radioactive waste disposal facility, scheduled to be constructed in Korea, will institute WAC for the wastes to be transferred to the facility. This WAC is expected to compose of the requirements for the radiological characterization, physical and chemical characterization, physical/chemical restriction, prohibited item, packaging, identification, labeling, and documentation. For the compliance with this regulation, The radioactive waste generators should verify that the waste meet WAC through performance of the waste certification program and are responsible for handing in all the certification documents to the disposal facility. This waste certification program plan was set up as a preliminary program for the certification of radioactive waste generated in Korea Atomic Energy Research Institute (KAERI) and should be further revised until preparation of WAC by disposal agent.