• 한국인구학
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• 제16권2호
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• pp.1-23
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• 1993

Korea fertility level has dropped since the 1960's and speed of decline has accelerated in the 1980's. In the resuls, the growth rate reached to less then 1 percent in 1990 and will be $\ulcorner$0 $\lrcorner$ percent growth in 2021. The total population will increase to 50, 586 thousand persons in 2021 then will decrease. With the rapid fertility decline the age structure of Korean population has changed : while the proportion of child population aged 0-14 is decreasing sharply, that of old-age population aged 65 and over is increasing. Because of the recent increase of sex ratio at birth, the sex structure among the young generation has been destorted; the sex ratio at age 0-4 was as high as high as 112.0 in 1990. The effects of these population phenomena on Korean society are the followings: 1) Old age dependency ratio is increasing rapidly and continuously and will be about 40.0 from the 2050's. 2) Because of the rapid decline of the number of births, the absolute number of the major labour force at age 25-34 will decrease after around 2000 and then from the 2010's become less than that in 1990. 3) Since the large fertility defferentials by womens's educational level have continued and the relation between the educational levels of mothers and children are very strong, level has dropped among higher educated women first when the average fertility level has declined in Korea, the average educational level of the children is may be expected to be relatively low and then the future productivity is will be also low, which causes the decline of 'quality of population. 4) When the high sex ratio at birth (over 110 since 1986) continues, number of brides will be short by over 20 percent from the 2010s, which will bring various kinds of social prblems. Therefore, the counter measures in concrete to relieve the heavy problems are recommended as follows: 1) The extention of the birth intervals, which helps to drop the population growth rate at the same level of number of children per women. 2) The positive supports for out-migrants, which helps to reduce the population size without any destortion of age-sex structure. 3) The defferent supports of family planning for the higher and lower classes, which helps to reduce the gaps between different ferility levels of the classes and to keep and improve the quality of population. 4)population education for both students and adults, which helps to minimize the gap between the private and public requirements.

• 한국토양비료학회지
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• 제12권1호
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• pp.1-14
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• 1979

한국(韓國) 답토양(畓土壤) 92개(個) 지점(地点)을 선정조사(選定調査)하고, 채취(採取)된 시료(施料)로 입도(粒度), 산도(酸度), 전도도(電導度), 전질소(全窒素), 유기물(有機物), 양(陽)이온 치환용량(置換容量), 치환성염기(置換性鹽基), 전인산(全燐酸), 유효인산(有效燐酸), 유리산화물(遊離酸化物) 및 유효규소(有效珪素) 등등(等等)의 26개(個) 항목(項目)의 토양분석(土壤分析) 결과(結果)를 가지고 쌀 생산력(生産力)에 미치는 중요인자(重要因)子 중(中)의 하나인 비옥도(肥沃度)를 정량적(定量的)으로 평가(評價)하고, 이 비옥도(肥沃度) 평가(評價)에 근거(根據)하여 객관적(客觀的)인 비옥도(肥沃度) 분류(分類)를 실행(實行)코저 한 바 다음과 같은 결과(結果)를 얻을 수 있었다. (1) 상관분석(相關分析) 및 예비자료(豫備資料) 분석(分析)을 통(通)하여 사(砂),미사(徵砂)+점토(粘土), 산도(酸度), 양(陽)이온 치환용량(置換容量), 치환성(置換性) 석회(石灰)+고토(苦土), 유기물(有機物), 전질소(全窒素), 암모니아태(態) 질소(窒素), Bray-P,0.2 N HCl-P, 전도도(電導度), 0.2N HCl-K, 치환성(置換性)나트륨, 유리산화철(遊離 酸化鐵), 유리산화(遊離酸化) 망간 등(等) 토양(土壤) 비옥도(肥沃度) 공통인자(共通因子) 추출(抽出)에 유용(有用)한 15개(個)의 변수(變數)가 얻어졌다. (2) 비옥도(肥沃度) 공통인자(共通因子)를 추출(抽出)하기 위하여 주성분(主成分) 분석(分析)(principal component analysis)을 행(行)하였든 바 고유치(固有値)(eigen value)가 1.0이상(以上)이고 누적기여율(累積寄與率)(Cumullative %)이 약(約) 80%인 5개(個)의 주성분(主成分)이 얻어졌다. (3) 주성분(主成分) 분석결과(分析結果) 얻어진 5개(個)의 주성분(主成分)은 각(各) 특성간(特性間)의 분리(分離)가 불명확(不明確)하여 해석(解析)이 곤란(困難)한 점(点)이 있었으므로 인자분석(因子分析)(factor analysis)의 일종(一種)인 Varimax 방법(方法)을 적용(適用)한 결과(結果) 해석(解析)이 가능(可能)한 5개(個)의 비옥도(肥沃度) 공통인자(共通因子) 즉 토성(土性)과 유효인산(有效燐酸), 유기물(有機物), 염분(鹽分), 염기(鹽基) 및 유리산화물(遊離酸化物) 상태(相態)를 나타내는 비옥도(肥沃度) 인자(因子)들이 추출(抽出)되었다. (4) 추출(抽出)된 비옥도(肥沃度) 인자평점계수행렬(因子評点係數行列)을 이용(利用)하여 각개체(各個體)에 대한 인자평점(因子評点)을 계산(計算)하여 수치분류(數値分類)(numerical taxonomy)를 행(行)한 결과(結果) 각각(各各) 특징(特徵)을 가진 7개(個)의 비옥도군(肥沃度群)으로 분류(分類)할 수 있었다. (5) 미분수(未分數)된 시료(試料)는 판별개수(判別關數)(discriminant function)법(法)에 의하여 7개군(個群) 중(中) 어느 한 군(群)으로 재분류(再分類)할 수 있었다.

• Clinical and Experimental Reproductive Medicine
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• 제39권4호
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• pp.144-152
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• 2012

Objective: Concerns are growing about the decrease in male reproductive health. Caffeine is one of the popular nutrients that has been implicated as a risk factor for infertility. In the present study, we examined whether in utero and lactational exposure to caffeine affects the reproductive function of the offspring of rats. Methods: Pregnant rats received caffeine via drinking water during gestation (26 and 45 mg/kg) and lactation (25 and 35 mg/kg). Body and reproductive organ weight, seminiferous tubule diameter, germinal epithelium height, sperm parameters, fertility rate, number of implantations, and testosterone level of the offspring were assessed from birth to adulthood. Results: Significant dose-related decreases were observed in the body and reproductive organ weight, seminiferous tubule diameter, and germinal epithelium height of the offspring. Sperm density had declined significantly in offspring of the low-dose and high-dose groups, by 8.81% and 19.97%, respectively, by postnatal day 150. The number of viable fetuses had decreased significantly in females mated with male offspring of the high-dose group at postnatal days 60, 90, 120, and 150. There were also significant reductions in testosterone levels of high-dose group offspring from birth to postnatal day 150. Conclusion: It is concluded that maternal caffeine consumption impairs gonadal development and has long-term adverse effects on the reproductive efficiency of male offspring rats.

• 가정∙방문간호학회지
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• 제14권1호
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• pp.11-17
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• 2007

The purpose of this study was to describe the policy agenda and alternatives for the home health care system in Korea. The home health care system development was not fully integrated while the medical laws were established in 2000, community health law in 1995, and elderly long-term health insurance law in 2007. Because of the increasing population of people over the age of 65 and dramatically decreasing fertility rate, the burden of various health-care expenses has become a great obstacle for the Korean government. Under these circumstances, the home of home health care system in has taken on an important role under the mandate of the national health care system. The types of home health care system in Korean shows a greater contrast from those utilized in other more industrialized countries, such as, U.S. or Japan. In conclusion, the strategy in overcoming the obstacles to enhance home health care system under the national health system would be developing it as a comprehensive and exchangeable consumer-focused organization.

• 한국임상수의학회지
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• 제33권2호
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• pp.138-141
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• 2016

The aim of this study was to diagnose the fertility of a female western lowland gorilla kept in Seoul Zoo, in accordance with age by analyzing the fecal sex hormone metabolites. The study was conducted in two period of times, when the animal was from 35 to 37 years old and when the animal was from 40 to 42 years old. Non-invasive method by using fecal samples was used for safe and efficient fertility diagnosis. We collected the feces from the enclosure at least three times a week. Then $17{\beta}$-estradiol and progesterone, which are fecal sex hormone metabolites, were measured by time-resolved fluoro-immunoassay to compare the menstruation cycle and the annual reproductive cycle. For the duration of the primary study (when the animal was 35~37 years old), irregular menstruation and high concentrations of estradiol and progesterone were observed. However, menstruation was hardly observed and the concentrations of both hormones were statistically very low in the period of secondary study (when the animal was 40~42 years old). This observed phenomenon in our study was very comparable to menopause in adult women; therefore, it was confirmed that our female gorilla has reached menopause because of the natural aging, as they become older.

• Human Ecology Research
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• 제60권1호
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• pp.147-162
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• 2022

Although the globally known one-child policy in China was abolished in 2016, the overall fertility rate in the country declined to 1.3 in 2020. In this study, we examined whether the achievement of major developmental tasks during the childrearing stage was associated with intentions to have a second child among Chinese married women. Based on family development theory, we included parenting adaptation, division of childcare responsibilities with the partner, and marital adjustment as key developmental tasks during the childrearing stage. The participants of this study were 315 married Chinese women who lived with a spouse and a child who had not yet entered elementary school. Data were collected through an online survey in February and March 2021. A multiple regression analysis of the data revealed that a lower level of economic parenting stress, a higher level of fairness in dividing childcare responsibilities with the partner, and a more positive change in their marital relationship after having the first child were associated with greater intentions to have a second child.

• 문화기술의 융합
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• 제9권6호
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• pp.729-736
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• 2023

전통적으로 성별분업에 의한 남성 생계부양자모델을 추구해온 보수주의 복지국가 독일은 오랜 기간 현금급여 중심의 경제적 지원을 통해 저출생 문제를 해결하고자 하였으나 성공하지 못했다. 2007년 독일 정부는 "시간정책, 이전소득 및 인프라의 혼합"이라는 슬로건 아래 일·가정 양립을 위한 가족정책 패러다임의 전환을 시작하였다. 독일에서 저출생 문제가 국가문제로 부상하자 정부뿐 아니라 민간 기업도 가족친화적 인사정책과 근로조건을 제공함으로써 출산율 향상에 기여해야 한다는 사회적 분위기가 조성되었다. 민간 기업은 인력 확보와 이직 예방을 목적으로 법적 의무를 넘어 자발적으로 가정친화적 근로환경을 개선해나가고 있다. 독일의 출산율은 2023년 현재 유럽 평균 수준으로 상승하고 있어 정부의 일·가정 양립정책과 민간 기업의 참여가 출산율 향상에 기여한 것으로 평가될 수 있다. 한국의 일·가정 양립 정책 개선 방안으로 아버지의 육아 동참 필요성에 대한 인식 전환, 남성 육아휴직의 의무화, 출산 후 여성의 고용 보장, 돌봄시설 확충 그리고 기업의 가족친화정책 활성화를 제안하였다.

• 문화기술의 융합
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• 제10권4호
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• pp.451-456
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• 2024

본 연구는 한국의 급격한 저출산과 고령화로 인한 군 인력 부족 문제를 진단하고, 그에 대한 대응 방안을 모색하는 데 목적이 있다. 이를 위해 한국의 인구 구조 변화 추이와 군 인력 수급 전망을 분석하고, 여군 확대, 모병제 도입, 첨단 무기 도입 등 주요 대안을 평가하였다. 또한 미국, 일본, 독일 등 주요국의 군 인력 정책 사례를 통해 시사점을 도출하고자 하였다. 연구 결과, 한국군의 지속가능한 인력 확보를 위해서는 여군 비율 제고, 장기적 관점의 모병제 검토, 병력 감축에 따른 전력 공백 최소화, 숙련 인력에 대한 인센티브 강화, 병역제도 개선과 국방개혁에 대한 사회적 합의 도출 등이 필요한 것으로 나타났다. 본 연구는 향후 한국군의 인력 정책 수립에 기여할 것으로 기대된다.

• Molecules and Cells
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• 제25권1호
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• pp.20-29
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• 2008

Cytoplasmic male sterility (CMS), one of the most important traits in crop breeding, has been used for commercial seed production by $F_1$ hybrid cultivars of pepper (Capsicum annuum L.). To develop reliable molecular markers for allelic selection of the Restorer-of-fertility (Rf) gene, which is known to be a major determinant of pollen fertility restoration in peppers, a sequence of approximately 10 kb flanking an RAPD fragment closely linked to the Rf locus was obtained by genome walking. A homology search revealed that this sequence contained an LTR retrotransposon and a non-LTR LINE-like retrotransposon. Sequencing of this Rf-linked region to search for polymorphisms between a dominant and recessive allele revealed 98% nucleotide sequence identity between them. A third polymorphic haplotype of the Rf-linked sequence, which has 94-96% nucleotide sequence identity with the two previously isolated haplotypes, was identified among a large number of breeding lines. Utilizing polymorphic sequences in the haplotypes, PCR markers were developed for selection of particular haplotypes and used to examine the distribution of the haplotypes in diverse breeding lines, cultivars, and C. annuum germplasms. Surprisingly, the third haplotype was the predominant type in C. annuum germplasms, while its frequency in $F_1$ hybrid cultivars was relatively low. Meanwhile, analysis of breeding lines whose Rf allele genotypes and male-sterility phenotypes were already known revealed that the third haplotype was mainly present in exotic breeding lines that cause unstable male-sterility when combined with sterile cytoplasms.

• 한국발생생물학회지:발생과생식
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• 제24권4호
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• pp.297-306
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• 2020

Repetitive changes in the intracellular calcium concentration ([Ca²⁺]i) triggers egg activation, including cortical granule exocytosis, resumption of second meiosis, block to polyspermy, and initiating embryonic development. [Ca²⁺]i oscillations that continue for several hours, are required for the early events of egg activation and possibly connected to further development to the blastocyst stage. The sources of Ca²⁺ ion elevation during [Ca²⁺]i oscillations are Ca²⁺ release from endoplasmic reticulum through inositol 1,4,5 tri-phosphate receptor and Ca²⁺ ion influx through Ca²⁺ channel on the plasma membrane. Ca²⁺ channels have been characterized into voltage-dependent Ca²⁺ channels (VDCCs), ligand-gated Ca²⁺ channel, and leak-channel. VDCCs expressed on muscle cell or neuron is specified into L, T, N, P, Q, and R type VDCs by their activation threshold or their sensitivity to peptide toxins isolated from cone snails and spiders. The present study was aimed to investigate the localization pattern of N and P/Q type voltage-dependent calcium channels in mouse eggs and the role in fertilization. [Ca²⁺]i oscillation was observed in a Ca²⁺ contained medium with sperm factor or adenophostin A injection but disappeared in Ca²⁺ free medium. Ca²⁺ influx was decreased by Lat A. N-VDCC specific inhibitor, ω-Conotoxin CVIIA induced abnormal [Ca²⁺]i oscillation profiles in SrCl₂ treatment. N or P/Q type VDC were distributed on the plasma membrane in cortical cluster form, not in the cytoplasm. Ca²⁺ influx is essential for [Ca²⁺]i oscillation during mammalian fertilization. This Ca²⁺ influx might be controlled through the N or P/Q type VDCCs. Abnormal VDCCs expression of eggs could be tested in fertilization failure or low fertilization eggs in subfertility women.