• 한국약용작물학회지
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• 제10권4호
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• pp.298-302
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• 2002

The essential oils were isolated by hydrodistillation and their composition determined capillary GC method with standards. The essential oil content showed significant differences between the two populations on the vegetative organs. The essential oil level of the leaves and roots was considerably higher in the Korean population at full flowering and waxy ripening stage but essential oil content of the roots was significantly higher in the Hungarian taxon at leaf rosette stage. We observed the essential oil accumulation tendency was mianly dependent on plant organs and intra-specific taxon during the vegeation period. Butylidene-phthalide was proved to be the main component of the oil in both population roots (50.9-73.3%), while dimethyl-acetate was showed as a major compound on the over-ground parts (56.7-62.0%). The qualitative composition of the essential oil in the reproductive organs concerning the identified compounds was the same as the vegetative parts with the main component ${\alpha}-phellandrene$ (4.8-28.1%) and butylidene-phtalide (9.7-16.1%), The quantitative composition showed some changes during the ontogenesis phases. Most characteristic ones are the decreasing proportion of dimethyl-acetate (from 7.3% to 1.1%) and the appearance of ${\alpha}-pinene$ (from 0.5% to 1.5%) only after fruit setting in both population.

• 한국식품저장유통학회지
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• 제10권1호
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• pp.94-98
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• 2003

율무, 옥수수, 메밀, 표고버섯, 당귀, 감초 및 대추의 물추출 혼합물(13 : 50 : 15 : 2 : 5 : 5 : 5, v/v) 이 쥐 혈청과 피부의 testosterone(T) 및 dihydrotestosterone(DHT) 함량과 간독성 및 생화학적 및 조직학적 변화에 미치는 영향을 조사하기 위하여 1일 9 mL/kg-BW 씩 음용수에 섞어 SD(Sprague-Dawley)계의 흰쥐에 5주 동안 투여하였으며, 5-a -reductase의 저해제로 알려진 propecia와 비교하였다. GOT, GPT, ALP 및 ${\gamma}$-GTP의 활성도와 total cholesterol 및 total lipid 함량은 무처리, propecia 및 식품소재추출물 투여군 간의 뚜렷한 차이를 보이지 않아 간 손상이 유발되지 않았다. 간의 조직학적 소견에서도 식품소재 추출물의 독 작용은 없는 것으로 판단되었다. 또, 식품소재추출물의 투여로 모낭수가 대조군에 비해 많았다. 혈청 및 피부의 T+DHT 함량은 식품소재추출물 투여군이 대조군에 비하여 유의적으로 감소하여 5-a-reductase의 활성이 저해되는 것으로 나타났다. 그러나 식품소재추출물과 propecia와의 유의적인 차이는 보이지 않았다.